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Original Articles

Intravenous-to-oral antibiotic switch therapy

A cost-effective approach

, MD
Pages 111-128 | Published online: 30 Jun 2015

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Burke A. Cunha. (2008) Oral and i.v.-to-p.o. switch antibiotic therapy of hospitalized patients with serious infections. Scandinavian Journal of Infectious Diseases 40:11-12, pages 1004-1006.
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Nisha P. Shah, Prabashni Reddy, Joseph A. Paladino, Peggy S. McKinnon, Michael E. Klepser & Chris L. Pashos. (2004) Direct medical costs associated with using vancomycin in methicillin-resistant Staphylococcus aureus infections: an economic model. Current Medical Research and Opinion 20:6, pages 779-790.
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Articles from other publishers (35)

John Ndayishimiye, Amirali Popat, Mark Blaskovich & James Robert Falconer. (2020) Formulation technologies and advances for oral delivery of novel nitroimidazoles and antimicrobial peptides. Journal of Controlled Release 324, pages 728-749.
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Aun Raza, Fekade Bruck Sime, Peter J. Cabot, Faheem Maqbool, Jason A. Roberts & James Robert Falconer. (2019) Solid nanoparticles for oral antimicrobial drug delivery: a review. Drug Discovery Today 24:3, pages 858-866.
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Cheston B. Cunha. (2018) The Pharmacoeconomic Aspects of Antibiotic Stewardship Programs. Medical Clinics of North America 102:5, pages 937-946.
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Zuying Felicia Woo, Wei Teng Chung, Jia En Wu & Hui Hiong Chen. (2018) An evaluation of the intravenous to oral antimicrobial conversion program in the inpatient setting. Journal of Pharmacy Practice and Research 48:3, pages 269-276.
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Ashley E. Skeith, Brenda Niu, Amy M. Valent, Methodius G. Tuuli & Aaron B. Caughey. (2017) Adding Azithromycin to Cephalosporin for Cesarean Delivery Infection Prophylaxis. Obstetrics & Gynecology 130:6, pages 1279-1284.
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Christine ChangKristen A Feemster, Susan Coffin & Lori K Handy. (2017) Treatment-Related Complications in Children Hospitalized With Disseminated Lyme Disease. Journal of the Pediatric Infectious Diseases Society 6:3, pages e152-e154.
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Unn Ljøstad, Eirik Skogvoll, Randi Eikeland, Rune Midgard, Tone Skarpaas, Åse Berg & Åse Mygland. (2008) Oral doxycycline versus intravenous ceftriaxone for European Lyme neuroborreliosis: a multicentre, non-inferiority, double-blind, randomised trial. The Lancet Neurology 7:8, pages 690-695.
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Kristof Steurbaut, Sofie Van Hoecke, Kirsten Colpaert, Chris Danneels, Johan Decruyenaere & Filip De Turck. 2008. Advances in Intelligent and Distributed Computing. Advances in Intelligent and Distributed Computing 207 216 .
Robert Hernandez. (2006) The use of systemic antibiotics in the treatment of chronic wounds. Dermatologic Therapy 19:6, pages 326-337.
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Jean-Paul Rwabihama, Romain Aubourg, Juliette Oliary, Stéphane Mouly, Karine Champion, Roger Leverge & Jean-François Bergmann. (2006) Usage et mésusage de la voie intraveineuse pour l’administration de médicaments en médecine interne. La Presse Médicale 35:10, pages 1453-1460.
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E. Schwartzberg, S. Rubinovich, D. Hassin, J. Haspel, A. Ben-Moshe, M. Oren & S. Shani. (2006) Developing and implementing a model for changing physicians' prescribing habits - the role of clinical pharmacy in leading the change. Journal of Clinical Pharmacy and Therapeutics 31:2, pages 179-185.
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Richard A. Santucci & John N. Krieger. 2006. Drug Treatment in Urology. Drug Treatment in Urology 96 119 .
Gregory P. Samsa, David B. Matchar, James Harnett & Jerome Wilson. (2005) A Cost-Minimization Analysis Comparing Azithromycin-Based and Levofloxacin-Based Protocols for the Treatment of Patients Hospitalized With Community-Acquired Pneumonia. Chest 128:5, pages 3246-3254.
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C.M. Luna, A. Monteverde, A. Rodríguez, C. Apezteguia, G. Zabert, S. Ilutovich, G. Menga, W. Vasen, A.R. Díez & J. Mera. (2005) Neumonía intrahospitalaria: guía clínica aplicable a Latinoamérica preparada en común por diferentes especialistas. Archivos de Bronconeumología 41:8, pages 439-456.
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C.M. Luna, A. Monteverde, A. Rodríguez, C. Apezteguia, G. Zabert, S. Ilutovich, G. Menga, W. Vasen, A.R. Díez & J. Mera. (2005) Clinical Guidelines for the Treatment of Nosocomial Pneumonia in Latin America: an Interdisciplinary Consensus Document. Archivos de Bronconeumología ((English Edition)) 41:8, pages 439-456.
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Jared T. Hagaman, Peter Yurkowski, Alexander Trott & Gregory W. Rouan. (2016) Getting Physicians to Make “The Switch”: The Role of Clinical Guidelines in the Management of Community-Acquired Pneumonia. American Journal of Medical Quality 20:1, pages 15-21.
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Dilip Nathwani, Jim Z Li, Dan A Balan, Richard J Willke, Brian E Rittenhouse, Essy Mozaffari, Manouche Tavakoli & Tom Tang. (2004) An economic evaluation of a European cohort from a multinational trial of linezolid versus teicoplanin in serious Gram-positive bacterial infections: the importance of treatment setting in evaluating treatment effects. International Journal of Antimicrobial Agents 23:4, pages 315-324.
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Marianne McCollum, David C. Rhew & Stephen Parodi. (2003) Cost analysis of switching from IV vancomycin to PO linezolid for the management of methicillin-resistant Staphylococcus species. Clinical Therapeutics 25:12, pages 3173-3189.
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Horacio López, Jim Z. Li, Dan A. Balan, Richard J. Willke, Brian E. Rittenhouse, Essy Mozaffari, Gabriela Vidal, Teresa Zitto & Tom Tang. (2003) Hospital resource use and cost of treatment with linezolid versus teicoplanin for treatment of serious gram-positive bacterial infections among hospitalized patients from South America and Mexico: Results from a multicenter trial. Clinical Therapeutics 25:6, pages 1846-1871.
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Erin R. Fox, M. Christina Beckwith & Linda S. Tyler. (2017) Pharmacy-Administered IV to Oral Therapeutic Interchange Program: Development, Implementation, and Cost-Assessment. Hospital Pharmacy 38:5, pages 444-452.
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Edward M. Grant, David P. Nicolau, Charles Nightingale & Richard Quintiliani. (2013) Minimal Interaction between Gatifloxacin and Oxycodone. The Journal of Clinical Pharmacology 42:8, pages 928-932.
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David C. Rhew & Scott R. Weingarten. (2001) ACHIEVING A SAFE AND EARLY DISCHARGE FOR PATIENTS WITH COMMUNITY-ACQUIRED PNEUMONIA. Medical Clinics of North America 85:6, pages 1427-1440.
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Burke A. Cunha. (2001) Oral or intravenous-to-oral antibiotic switch therapy for treating patients with community-acquired pneumonia. The American Journal of Medicine 111:5, pages 412-413.
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Thuan P. Le & Loren G. Miller. (2001) Empirical Therapy for Uncomplicated Urinary Tract Infections in an Era of Increasing Antimicrobial Resistance: A Decision and Cost Analysis. Clinical Infectious Diseases 33:5, pages 615-621.
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M. Lelekis & I.M. Gould. (2001) Sequential antibiotic therapy for cost containment in the hospital setting: why not?. Journal of Hospital Infection 48:4, pages 249-257.
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Linda D. Dresser, Michael S. Niederman & Joseph A. Paladino. (2001) Cost-effectiveness of Gatifloxacin vs Ceftriaxone With a Macrolide for the Treatment of Community-Acquired Pneumonia. Chest 119:5, pages 1439-1448.
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Edward M. Grant, Ming Kang Zhong, James F. Fitzgerald, David P. Nicolau, Charles Nightingale & Richard Quintiliani. (2013) Lack of Interaction between Levofloxacin and Oxycodone: Pharmacokinetics and Drug Disposition. The Journal of Clinical Pharmacology 41:2, pages 206-209.
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Burke A. Cunha. (2001) COMMUNITY-ACQUIRED PNEUMONIA. Medical Clinics of North America 85:1, pages 43-77.
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RICHARD A. SANTUCCI & JOHN N. KRIEGER &NA;. (2000) GENTAMICIN FOR THE PRACTICING UROLOGIST:. The Journal of Urology, pages 1076-1084.
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RICHARD A. SANTUCCI & JOHN N. KRIEGER. (2000) GENTAMICIN FOR THE PRACTICING UROLOGIST: REVIEW OF EFFICACY, SINGLE DAILY DOSING AND “SWITCH” THERAPY. Journal of Urology 163:4, pages 1076-1084.
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Gene A. Wetzstein. (2017) Intravenous to Oral (IV:PO) Anti-Infective Conversion Therapy. Cancer Control 7:2, pages 170-176.
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A. Béresniak & G. Bouvenot. (2000) Utilisation de la pharmacoéconomie en antibiothérapie. Médecine et Maladies Infectieuses 30:3, pages 133-140.
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Fahad A. Al-Eidan, James C. McElnay, M. G. Scott, M. P. Kearney, K. E. U. Troughton & J. Jenkins. (1999) Sequential antimicrobial therapy: treatment of severe lower respiratory tract infections in children. Journal of Antimicrobial Chemotherapy 44:5, pages 709-715.
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Burke A. Cunha. (1998) ANTIBIOTIC RESISTANCE. Critical Care Clinics 14:2, pages 309-327.
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S C ChienM C RoggeL G GisclonC CurtinF WongJ NatarajanR R WilliamsC L FowlerW K CheungA T Chow. (1997) Pharmacokinetic profile of levofloxacin following once-daily 500-milligram oral or intravenous doses. Antimicrobial Agents and Chemotherapy 41:10, pages 2256-2260.
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