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Postgraduate Medicine Volume 122, 2010 - Issue 3
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Clinical Focus: Diabetes

Insulin—Carcinogen or Mitogen? Preclinical and Clinical Evidence from Prostate, Breast, Pancreatic, and Colorectal Cancer Research

Rosemary Call University of Mississippi School of Pharmacy, Jackson, MS
, BPharm,
Molly Grimsley University of Mississippi School of Pharmacy, Jackson, MS
, BPharm,
Lucy Cadwallader University of Mississippi School of Pharmacy, Jackson, MS
, BPharm,
Laura Cialone University of Mississippi School of Pharmacy, Jackson, MS
, BPharm,
Matt Hill University of Mississippi School of Pharmacy, Jackson, MS
, BPharm,
Vera Hreish University of Mississippi School of Pharmacy, Jackson, MS
, BPharm,
S. Travis King University of Mississippi School of Pharmacy, Jackson, MS
, PharmD &
Daniel M. Riche University of Mississippi School of Pharmacy, Jackson, MS; University of Mississippi School of Medicine, Jackson, MSCorrespondence[email protected]
, PharmD, BCPS, CDE show all
Pages 158-165 | Published online: 13 Mar 2015

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Thomas Forst, Markolf Hanefeld & Andreas Pfützner. (2011) Review of approved pioglitazone combinations for type 2 diabetes. Expert Opinion on Pharmacotherapy 12:10, pages 1571-1584.
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Articles from other publishers (24)

Harold Edward Bays, Shagun Bindlish & Tiffany Lowe Clayton. (2023) Obesity, diabetes mellitus, and cardiometabolic risk: An Obesity Medicine Association (OMA) Clinical Practice Statement (CPS) 2023. Obesity Pillars 5, pages 100056.
Crossref
Marjan Sharifi Nasab, Hamide Yazdimoghaddam, Seyedeh Tahereh Mohaddes & Mohammad Hasan Rakhshani. (2022) Association between Diabetes and Controlling Risk Factors with Survival Rate in Colorectal Cancer. Journal of Advances in Medical and Biomedical Research 30:1, pages 1-6.
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Mayur S. Mitra, Steven DeMarco, Brad Holub, Lakshmanan Thiruneelakantapillai & Evan A. Thackaberry. (2020) Development of peptide therapeutics: A nonclinical safety assessment perspective. Regulatory Toxicology and Pharmacology 117, pages 104766.
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Adrian Stelzl, Faisal Aziz, Jakob M. Riedl, Florian Posch, Maria A. Smolle, Tatjana Stojakovic, Angelika Terbuch, Martin Pichler, Marko Bergovec, Andreas Leithner, Bernadette Liegl-Atzwanger, Michael Stotz, Armin Gerger, Harald Sourij & Joanna Szkandera. (2020) Diabetes mellitus is independently associated with adverse clinical outcome in soft tissue sarcoma patients. Scientific Reports 10:1.
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Sasikumar Ponnusamy, Rodrigo Mosca, Karishma Desai & Praveen Arany. 2020. Wound Healing, Tissue Repair, and Regeneration in Diabetes. Wound Healing, Tissue Repair, and Regeneration in Diabetes 305 321 .
Yi-Chun Liu, Phung-Anh Nguyen, Ayesha Humayun, Shuo-Chen Chien, Hsuan-Chia Yang, Rahma Novita Asdary, Shabbir Syed-Abdul, Min-Huei Hsu, Max Moldovan, Yun Yen, Yu-Chuan (Jack) Li, Wen-Shan Jian & Usman Iqbal. (2019) Does long-term use of antidiabetic drugs changes cancer risk?. Medicine 98:40, pages e17461.
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Hao-Jun Shi, Chen Jin & De-Liang Fu. (2017) Impact of postoperative glycemic control and nutritional status on clinical outcomes after total pancreatectomy. World Journal of Gastroenterology 23:2, pages 265.
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Chin-Hsiao Tseng. (2015) Prolonged use of human insulin increases breast cancer risk in Taiwanese women with type 2 diabetes. BMC Cancer 15:1.
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Jennifer W. Harris, Tianyan Gao & B. Mark Evers. 2015. Intestinal Tumorigenesis. Intestinal Tumorigenesis 101 135 .
Muhammad Shaalan Beg, Alok Kumar Dwivedi, Syed Arif Ahmad, Sadia Ali & Olugbenga Olowokure. (2014) Impact of Diabetes Mellitus on the Outcome of Pancreatic Cancer. PLoS ONE 9:5, pages e98511.
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J Luo, H-C Lin, K He & M Hendryx. (2014) Diabetes and prognosis in older persons with colorectal cancer. British Journal of Cancer 110:7, pages 1847-1854.
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Chin-Hsiao Tseng. (2014) Human Insulin Does Not Increase Prostate Cancer Risk in Taiwanese. Clinical Genitourinary Cancer 12:1, pages e7-e12.
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Melissa Kang & Temitope O. Keku. 2014. Impact of Energy Balance on Cancer Disparities. Impact of Energy Balance on Cancer Disparities 131 163 .
Jennifer H. Gunter, Phoebe L. Sarkar, Amy A. Lubik & Colleen C. Nelson. (2013) New Players for Advanced Prostate Cancer and the Rationalisation of Insulin-Sensitising Medication. International Journal of Cell Biology 2013, pages 1-13.
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L. Braccini, E. Ciraolo, M. Martini, T. Pirali, G. Germena, K. Rolfo & E. Hirsch. (2012) PI3K keeps the balance between metabolism and cancer. Advances in Biological Regulation 52:3, pages 389-405.
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Yingmei Wang, Yuanxi Zhu, Lizhi Zhang, Wenyan Tian, Shaofang Hua, Jing Zhao, Huiying Zhang & Fengxia Xue. (2012) Insulin promotes proliferation, survival, and invasion in endometrial carcinoma by activating the MEK/ERK pathway. Cancer Letters 322:2, pages 223-231.
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P. Blin, R. Lassalle, C. Dureau-Pournin, B. Ambrosino, M. A. Bernard, A. Abouelfath, H. Gin, C. Le Jeunne, A. Pariente, C. Droz & N. Moore. (2012) Insulin glargine and risk of cancer: a cohort study in the French National Healthcare Insurance Database. Diabetologia 55:3, pages 644-653.
Crossref
Jennifer H. Gunter, Amy A. Lubik, Ian McKenzie, Michael Pollak & Colleen C. Nelson. (2012) The Interactions between Insulin and Androgens in Progression to Castrate-Resistant Prostate Cancer. Advances in Urology 2012, pages 1-11.
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Elaine Manoela Porto, Sérgio Alexandre De Alcântara Dos Santos, Larissa Mayumi Ribeiro, Lívia Maria Lacorte, Jaqueline Carvalho Rinaldi, Luis Antonio JustulinJrJr & Sérgio Luís Felisbino. (2011) Lobe variation effects of experimental diabetes and insulin replacement on rat prostate. Microscopy Research and Technique 74:11, pages 1040-1048.
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Amal Melhem-BertrandtMariana Chavez-MacGregorXiudong LeiErika N. BrownRichard T. LeeFunda Meric-BernstamAnil K. SoodSuzanne D. ConzenGabriel N. HortobagyiAna-Maria Gonzalez-Angulo. (2011) Beta-Blocker Use Is Associated With Improved Relapse-Free Survival in Patients With Triple-Negative Breast Cancer. Journal of Clinical Oncology 29:19, pages 2645-2652.
Crossref
Ryaz B. Chagpar, Robert C. G. Martin, Syed A. Ahmad, Hong Jin Kim, Christopher Rupp, Sharon Weber, Andrew Ebelhar, Juliana Gilbert, Adam Brinkman, Emily Winslow, Clifford S. Cho, David Kooby, Carrie K. Chu, Charles A. Staley, Kelly M. McMasters & Charles R. Scoggins. (2011) Medically Managed Hypercholesterolemia and Insulin-Dependent Diabetes Mellitus Preoperatively Predicts Poor Survival after Surgery for Pancreatic Cancer. Journal of Gastrointestinal Surgery 15:4, pages 551-557.
Crossref
M. V. Seeman. (2011) Preventing breast cancer in women with schizophrenia. Acta Psychiatrica Scandinavica 123:2, pages 107-117.
Crossref
T. A. Chowdhury. (2010) Diabetes and Cancer. QJM 103:12, pages 905-915.
Crossref
Hungdai Kim. (2010) Does Diabetes Really Impact on Postoperative Survival in Patients with Colorectal Cancer?. Journal of the Korean Society of Coloproctology 26:6, pages 376.
Crossref

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