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Clinical Features

Iloperidone, Asenapine, and Lurasidone: A Brief Overview of 3 New Second-Generation Antipsychotics

, MD, MPH
Pages 153-162 | Published online: 13 Mar 2015

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L. Orsolini, C. Tomasetti, A. Valchera, R. Vecchiotti, I. Matarazzo, F. Vellante, F. Iasevoli, E. F. Buonaguro, M. Fornaro, A. L. C. Fiengo, G. Martinotti, M. Mazza, G. Perna, A. Carano, A. De Bartolomeis, M. Di Giannantonio & D. De Berardis. (2016) An update of safety of clinically used atypical antipsychotics. Expert Opinion on Drug Safety 15:10, pages 1329-1347.
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Rachel Franklin, Sam Zorowitz, Andrew K Corse, Alik S Widge & Thilo Deckersbach. (2015) Lurasidone for the treatment of bipolar depression: an evidence-based review. Neuropsychiatric Disease and Treatment 11, pages 2143-2152.
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Young Sup Woo, Hee Ryung Wang & Won-Myong Bahk. (2013) Lurasidone as a potential therapy for bipolar disorder. Neuropsychiatric Disease and Treatment 9, pages 1521-1529.
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Joshua T Kantrowitz & Leslie Citrome. (2012) Lurasidone for schizophrenia: what’s different?. Expert Review of Neurotherapeutics 12:3, pages 265-273.
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Leslie Citrome. (2011) Role of sublingual asenapine in treatment of schizophrenia. Neuropsychiatric Disease and Treatment 7, pages 325-339.
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Chris M. Kozma, Terra Slaton, Riad Dirani, John Fastenau, Srihari Gopal & David Hough. (2011) Changes in schizophrenia-related hospitalization and ER use among patients receiving paliperidone palmitate: results from a clinical trial with a 52-week open-label extension (OLE). Current Medical Research and Opinion 27:8, pages 1603-1611.
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Mohammed Sawan, Tarek Nayfeh, Abdul M Majzoub, Homam Alabaji, Saria Alnahas, Tareq Al Saadi & Adib Essali. (2015) Iloperidone versus placebo for schizophrenia. Cochrane Database of Systematic Reviews.
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Michelle A. Worthington & Rif S. El-Mallakh. (2015) A Naturalistic Retrospective Review of Weight Gain in Bipolar Patients Treated With Second Generation Antipsychotics. Journal of Clinical Psychopharmacology 35:2, pages 192-193.
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George Awad, Mariam Hassan, Antony Loebel, Jay Hsu, Andrei Pikalov & Krithika Rajagopalan. (2014) Health-related quality of life among patients treated with lurasidone: results from a switch trial in patients with schizophrenia. BMC Psychiatry 14:1.
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Tom Parke, Vladimir Dragalin, Ibrahim Turkoz, Olga Marchenko & Virginia Haynes. (2014) Adaptive Design Applied to Identification of the Minimum Effective Dose in Schizophrenia. Therapeutic Innovation & Regulatory Science 48:1, pages 41-50.
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Leslie Citrome. (2013) A Review of the Pharmacology, Efficacy and Tolerability of Recently Approved and Upcoming Oral Antipsychotics: An Evidence-Based Medicine Approach. CNS Drugs 27:11, pages 879-911.
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A. George Awad & Lakshmi N. P. Voruganti. (2013) The Impact of Newer Atypical Antipsychotics on Patient-Reported Outcomes in Schizophrenia. CNS Drugs 27:8, pages 625-636.
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Melvin George, Radhika Amrutheshwar, Ravi Philip Rajkumar, Shivanand Kattimani & Steven Aibor Dkhar. (2013) Newer antipsychotics and upcoming molecules for schizophrenia. European Journal of Clinical Pharmacology 69:8, pages 1497-1509.
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Lindsay N. Cates, Amanda J. Roberts, Salvador Huitron-Resendiz & Peter B. Hedlund. (2013) Effects of lurasidone in behavioral models of depression. Role of the 5-HT7 receptor subtype. Neuropharmacology 70, pages 211-217.
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Herbert Y. Meltzer. (2013) Update on Typical and Atypical Antipsychotic Drugs. Annual Review of Medicine 64:1, pages 393-406.
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Heidi N. Boyda, Ric M. Procyshyn, Catherine C. Y. Pang, Erin Hawkes, Daniel Wong, Chen Helen Jin, William G. Honer & Alasdair M. Barr. (2013) Metabolic Side-Effects of the Novel Second-Generation Antipsychotic Drugs Asenapine and Iloperidone: A Comparison with Olanzapine. PLoS ONE 8:1, pages e53459.
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Marc De Hert, Weiping Yu, Johan Detraux, Kim Sweers, Ruud van Winkel & Christoph U. Correll. (2012) Body Weight and Metabolic Adverse Effects of Asenapine, Iloperidone, Lurasidone and Paliperidone in the Treatment of Schizophrenia and Bipolar Disorder. CNS Drugs 26:9, pages 733-759.
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Amaia López de Torre, Unax Lertxundi, Rafael Hernández & Juan Medrano. (2012) Antipsychotic polypharmacy: a needle in a haystack?. General Hospital Psychiatry 34:4, pages 423-432.
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W. Wolfgang Fleischhacker & Alex Hofer. 2012. Handbuch der Psychopharmakotherapie. Handbuch der Psychopharmakotherapie 937 960 .
Marsal Sanches & Jair C. Soares. (2011) New Drugs for Bipolar Disorder. Current Psychiatry Reports 13:6, pages 513-521.
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Norman L. Keltner, Randy L. Moore & Joan S. Grant. (2011) Biological Perspectives: Update on Newer Antipsychotic Drugs: Are They Evidence Based?. Perspectives in Psychiatric Care 47:4, pages 220-226.
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Leslie Citrome. (2011) Treatment-refractory schizophrenia: what is it and what has been done about it?. Neuropsychiatry 1:4, pages 325-347.
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Young Sup WooWon-Myong Bahk. (2011) Recent advances in the pharmacotherapy of psychiatric disorders. Journal of the Korean Medical Association 54:10, pages 1061.
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