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Postgraduate Medicine Volume 124, 2012 - Issue 6
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Clinical Features

Effects of Multiple Doses of Albiglutide on the Pharmacokinetics, Pharmacodynamics, and Safety of Digoxin, Warfarin, or a Low-Dose Oral Contraceptive

Mark Bush Formerly GlaxoSmithKline, Clinical Pharmacology Modeling and Simulation, Research Triangle Park, NCCorrespondence[email protected]
, PhD,
Rhona Scott GlaxoSmithKline, Biopharm R&D, Stockley Park, United Kingdom
, BSc Hons,
Prapoch Watanalumlerd PPD, Inc., Clinical Pharmacology, Richmond, VA
, PhD,
Hui Zhi GlaxoSmithKline, Discovery Biometrics, Research Triangle Park, NC
, PhD &
Eric Lewis GlaxoSmithKline, Biopharm R&D, Research Triangle Park, NC
, MD
Pages 55-72 | Published online: 13 Mar 2015

Citations (16)

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Heather N Woodward & Sarah L Anderson. (2014) Once-weekly albiglutide in the management of type 2 diabetes: patient considerations. Patient Preference and Adherence 8, pages 789-803.
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Malcolm A. Young, Jeffrey A. Wald, Jessica E. Matthews, Rhona Scott, Rebecca J. Hodge, Hui Zhi & Rickey R. Reinhardt. (2014) Clinical Pharmacology of Albiglutide, a GLP-1 Receptor Agonist. Postgraduate Medicine 126:7, pages 84-97.
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Articles from other publishers (14)

Yaochen Xie, Qian Zhou, Qiaojun He, Xiaoyi Wang & Jincheng Wang. (2023) Opportunities and challenges of incretin-based hypoglycemic agents treating type 2 diabetes mellitus from the perspective of physiological disposition. Acta Pharmaceutica Sinica B 13:6, pages 2383-2402.
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Katrijn Bogman, Jochen Brumm, Carsten Hofmann, Mylène Giraudon, Markus Niggli, Carolina Sturm-Pellanda, Annette Sauter, Stefan Sturm, Bernhard Mangold & Christophe Schmitt. (2019) Assessment of Drug–Drug Interactions between Taspoglutide, a Glucagon-Like Peptide-1 Agonist, and Drugs Commonly Used in Type 2 Diabetes Mellitus: Results of Five Phase I Trials. Clinical Pharmacokinetics 58:9, pages 1205-1214.
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Bonnie C. Shaddinger, Georgios Vlasakakis, Joseph Soffer, Karl M. Thorpe, Daniel Hatch & Antonio J. Nino. (2018) A Randomized, Double‐Blind, Single‐Dose, Crossover Study to Demonstrate the Bioequivalence of 2 Formulations of Albiglutide in Healthy Adult Participants. Clinical Pharmacology in Drug Development 8:3, pages 361-370.
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Naina Mohamed Pakkir Maideen . (2019) Pharmacologically relevant drug interactions of Glucagon-like peptide-1 receptor agonists. Journal of Analytical & Pharmaceutical Research 8:2, pages 51-53.
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Helene Hausner, Julie Derving Karsbøl, Anders G. Holst, Jacob B. Jacobsen, Frank-Dietrich Wagner, Georg Golor & Thomas W. Anderson. (2017) Effect of Semaglutide on the Pharmacokinetics of Metformin, Warfarin, Atorvastatin and Digoxin in Healthy Subjects. Clinical Pharmacokinetics 56:11, pages 1391-1401.
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Amparo de la Peña, Xuewei Cui, Jeanne Geiser & Corina Loghin. (2017) No Dose Adjustment is Recommended for Digoxin, Warfarin, Atorvastatin or a Combination Oral Contraceptive When Coadministered with Dulaglutide. Clinical Pharmacokinetics 56:11, pages 1415-1427.
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Andreas Brønden, Filip K. Knop & Mikkel B. Christensen. (2017) Clinical Pharmacokinetics and Pharmacodynamics of Albiglutide. Clinical Pharmacokinetics 56:7, pages 719-731.
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Lei Chen, Yu-Hang Zhang, Quan Zou, Chen Chu & Zhiliang Ji. (2016) Analysis of the chemical toxicity effects using the enrichment of Gene Ontology terms and KEGG pathways. Biochimica et Biophysica Acta (BBA) - General Subjects 1860:11, pages 2619-2626.
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Arun K. Sharma, Punniyakoti V. Thanikachalam & Satyendra K. Rajput. (2016) Albiglutide: Is a better hope against diabetes mellitus?. Biomedicine & Pharmacotherapy 77, pages 120-128.
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Portia N. Davis, Uche Anadu Ndefo, Ashley Oliver & Enryka Payton. (2015) Albiglutide: A once-weekly glucagon-like peptide-1 receptor agonist for type 2 diabetes mellitus. American Journal of Health-System Pharmacy 72:13, pages 1097-1103.
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Christoph Kapitza, Leszek Nosek, Lene Jensen, Helle Hartvig, Christine B. Jensen & Anne Flint. (2015) Semaglutide, a once‐weekly human GLP‐1 analog, does not reduce the bioavailability of the combined oral contraceptive, ethinylestradiol/levonorgestrel. The Journal of Clinical Pharmacology 55:5, pages 497-504.
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Hannah A. Blair & Gillian M. Keating. (2015) Albiglutide: A Review of Its Use in Patients with Type 2 Diabetes Mellitus. Drugs 75:6, pages 651-663.
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Jennifer M. Trujillo & Wesley Nuffer. (2014) Albiglutide. Annals of Pharmacotherapy 48:11, pages 1494-1501.
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Raewyn M. Poole & Mary L. Nowlan. (2014) Albiglutide: First Global Approval. Drugs 74:8, pages 929-938.
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