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Future Science OA Volume 1, 2015 - Issue 4

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Research Article

Importance of Measuring Testosterone in Enzyme-Inhibited Plasma for Oral Testosterone Undecanoate Androgen Replacement Therapy Clinical Trials

Sylvain Lachance1 inVentiv Health clinical, Québec, CanadaCorrespondence[email protected]

Om Dhingra2 SOV Therapeutics, Morrisville, NC, USA

James Bernstein2 SOV Therapeutics, Morrisville, NC, USA

Stéphanie Gagnon1 inVentiv Health clinical, Québec, Canada

Caroline Savard1 inVentiv Health clinical, Québec, Canada

Nathalie Pelletier1 inVentiv Health clinical, Québec, Canada

Nadine Boudreau1 inVentiv Health clinical, Québec, Canada

Ann Lévesque1 inVentiv Health clinical, Québec, Canada

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Article: FSO55 | Published online: 26 Jun 2015

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Hua Gao, Jing-Yi Zhang, Li-Jie Zhao & Yuan-Yuan Guo. (2024) Synthesis and application of clinically approved small-molecule drugs targeting androgen receptor. Bioorganic Chemistry 143, pages 106998.
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Pratik Kanabur, Robert BrunnerDalia KheraHunter A. FloresMohit Khera. (2022) The Evolving Role of Novel Oral Agents for Testosterone Replacement Therapy; A Historical Perspective. Androgens: Clinical Research and Therapeutics 3:1, pages 224-232.
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William B. White, James S. Bernstein, Roger Rittmaster & Om Dhingra. (2021) Effects of the oral testosterone undecanoate Kyzatrex™ on ambulatory blood pressure in hypogonadal men. The Journal of Clinical Hypertension 23:7, pages 1420-1430.
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Atheer Zgair, Yousaf Dawood, Suhaib M. Ibrahem, Jong Bong Lee, Wanshan Feng, Peter M. Fischer & Pavel Gershkovich. (2021) Strawberry Decreases Intraluminal and Intestinal Wall Hydrolysis of Testosterone Undecanoate. Molecules 26:1, pages 233.
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Atheer Zgair, Yousaf Dawood, Suhaib M. Ibrahem, Hyun-moon Back, Leonid Kagan, Pavel Gershkovich & Jong Bong Lee. (2020) Predicting Intestinal and Hepatic First-Pass Metabolism of Orally Administered Testosterone Undecanoate. Applied Sciences 10:20, pages 7283.
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Ronald S Swerdloff, Christina Wang, William B White, Jed Kaminetsky, Marc C Gittelman, James A Longstreth, Robert E Dudley & Theodore M Danoff. (2020) A New Oral Testosterone Undecanoate Formulation Restores Testosterone to Normal Concentrations in Hypogonadal Men. The Journal of Clinical Endocrinology & Metabolism 105:8, pages 2515-2531.
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Ronald S. Swerdloff & Robert E. Dudley. (2020) A new oral testosterone undecanoate therapy comes of age for the treatment of hypogonadal men. Therapeutic Advances in Urology 12, pages 175628722093723.
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J. Ceponis, R. Swerdloff, A. Leung, L. Hull, F. Bai, J. Longstreth, R. Dudley, T. Danoff & C. Wang. (2018) Accurate measurement of androgen after androgen esters: problems created by ex vivo esterase effects and LC ‐ MS / MS interference . Andrology 7:1, pages 42-52.
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Importance of Measuring Testosterone in Enzyme-Inhibited Plasma for Oral Testosterone Undecanoate Androgen Replacement Therapy Clinical Trials

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Importance of Measuring Testosterone in Enzyme-Inhibited Plasma for Oral Testosterone Undecanoate Androgen Replacement Therapy Clinical Trials

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