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Cancer Biology & Therapy Volume 15, 2014 - Issue 11
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Research Paper

Polymorphisms of p53 and MDM2 genes are associated with severe toxicities in patients with non-small cell lung cancer

Datong ZhengDepartment of Biological Science and Technology and State Key Laboratory of Pharmaceutical Biotechnology; School of Life Sciences; Nanjing University; Nanjing, China;The Research Center; Second Hospital; Nanjing Medical University; Nanjing, China
,
Yanping ChenThe Research Center; Second Hospital; Nanjing Medical University; Nanjing, China
,
Caijie GaoThe Research Center; Second Hospital; Nanjing Medical University; Nanjing, China
,
Yongyue WeiThe Research Center; Second Hospital; Nanjing Medical University; Nanjing, China
,
Guochun CaoNanjing Medical University Affiliated Cancer Hospital; Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research; Nanjing, China
,
Nan LuSchool of Clinical Medicine; Shanghai Medical College; Fudan University; Shanghai, China
,
Yayi HouImmunology and Reproductive Biology Lab & Jiangsu Key Laboratory of Molecular Medicine; Medical School; Nanjing University; Nanjing, China
,
Xiuqin JiangThe Research Center; Second Hospital; Nanjing Medical University; Nanjing, ChinaCorrespondence[email protected] [email protected]
&
Jianjun WangDepartment of Biological Science and Technology and State Key Laboratory of Pharmaceutical Biotechnology; School of Life Sciences; Nanjing University; Nanjing, ChinaCorrespondence[email protected] [email protected]
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Pages 1542-1551 | Received 10 Jan 2014, Accepted 16 Aug 2014, Published online: 16 Dec 2014

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Ramón Cacabelos, Natalia Cacabelos & Juan C. Carril. (2019) The role of pharmacogenomics in adverse drug reactions. Expert Review of Clinical Pharmacology 12:5, pages 407-442.
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Articles from other publishers (10)

Jelena Spasić, Davorin Radosavljević & Ljudmila Nagorni-Obradović. (2021) The influence of genetic polymorphisms on the toxicity of platinum-based chemotherapy in the treatment of non-small cell lung cancer. Medicinski podmladak 72:2, pages 40-47.
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Yi Zheng, Zheng Deng, Mimi Tang, Di Xiao & Pei Cai. (2020) Impact of genetic factors on platinum-induced gastrointestinal toxicity. Mutation Research/Reviews in Mutation Research 786, pages 108324.
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Ericka Francislaine Dias Costa, Tathiane Regine Penna Lima, Leisa Lopes-Aguiar, Guilherme Augusto Silva Nogueira, Marília Berlofa Visacri, Julia Coelho França Quintanilha, Eder Carvalho Pincinato, Luciane Calonga, Fernanda Viviane Mariano, Albina Messias de Almeida Milani Altemani, João Maurício Carrasco Altemani, Patrícia Moriel, Carlos Takahiro Chone, Celso Dario Ramos & Carmen Silvia Passos Lima. (2020) FAS and FASL variations in outcomes of tobacco- and alcohol-related head and neck squamous cell carcinoma patients . Tumor Biology 42:7, pages 101042832093849.
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Wenhui Liu, Ying Wang, Jianquan Luo, Haiyan Yuan & Zhiying Luo. (2020) Genetic Polymorphisms and Platinum-Based Chemotherapy-Induced Toxicities in Patients With Lung Cancer: A Systematic Review and Meta-Analysis. Frontiers in Oncology 9.
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Bingjie Zou, Nan Sheng, Liying Feng & Guohua Zhou. 2020. Pharmacogenomics in Precision Medicine. Pharmacogenomics in Precision Medicine 201 218 .
Mette Marcussen, Conni Skrubbeltrang, Julie Støve Bødker, Ilse Christiansen, Martin Bøgsted, Karen Dybkær, Olav Jonas Bergmann & Hans Erik Johnsen. (2017) A systematic review of molecular responses to cancer therapy in normal human mucosa. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 124:4, pages 355-366.
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Cristina Pérez-Ramírez, Marisa Cañadas-Garre, Miguel Ángel Molina, Ana I. Robles, María José Faus-Dáder & Miguel Ángel Calleja-Hernández. (2017) Contribution of genetic factors to platinum-based chemotherapy sensitivity and prognosis of non-small cell lung cancer. Mutation Research/Reviews in Mutation Research 771, pages 32-58.
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Nannan Feng, Guoqiao Zheng, Yanhui Hao, Yong Li, Yandan Xu, Xiaowen Xu, Guanghui Zhang, Jinwei Wang, Yongliang Li, Paul Brandt-Rauf & Zhao-lin Xia. (2017) Mutations in apoptotic genes and micronucleus occurrence in vinyl chloride-exposed workers in China. Environmental and Molecular Mutagenesis 58:1, pages 39-45.
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Irene Vanni, Simona Coco, Anna Truini, Marta Rusmini, Maria Dal Bello, Angela Alama, Barbara Banelli, Marco Mora, Erika Rijavec, Giulia Barletta, Carlo Genova, Federica Biello, Claudia Maggioni & Francesco Grossi. (2015) Next-Generation Sequencing Workflow for NSCLC Critical Samples Using a Targeted Sequencing Approach by Ion Torrent PGM™ Platform. International Journal of Molecular Sciences 16:12, pages 28765-28782.
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Ji Qian, Hongliang Liu, Shaohua Gu, Qihan Wu, Xueying Zhao, Wenting Wu, Haijian Wang, Jiucun Wang, Hongyan Chen, Wei Zhang, Qingyi Wei, Li Jin & Daru Lu. (2015) Genetic Variants of the MDM2 Gene Are Predictive of Treatment-Related Toxicities and Overall Survival in Patients With Advanced NSCLC. Clinical Lung Cancer 16:5, pages e37-e53.
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