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The mitochondria-targeted antioxidant SkQ1 restores αB-crystallin expression and protects against AMD-like retinopathy in OXYS rats

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Pages 3499-3505 | Received 30 May 2014, Accepted 21 Aug 2014, Published online: 10 Dec 2014

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Darya V Telegina, Elena E Korbolina, Nikita I Ershov, Nataliya G Kolosova & Oyuna S Kozhevnikova. (2015) Identification of functional networks associated with cell death in the retina of OXYS rats during the development of retinopathy. Cell Cycle 14:22, pages 3544-3556.
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Articles from other publishers (22)

Natalia A. Muraleva & Nataliya G. Kolosova. (2023) Alteration of the MEK1/2–ERK1/2 Signaling Pathway in the Retina Associated with Age and Development of AMD-Like Retinopathy. Biochemistry (Moscow) 88:2, pages 179-188.
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Nataliya G. Kolosova, Oyuna S. Kozhevnikova, Natalia A. Muraleva, Ekaterina A. Rudnitskaya, Yuliya V. Rumyantseva, Natalia A. Stefanova, Darya V. Telegina, Mikhail A. Tyumentsev & Anzhella Zh. Fursova. (2023) SkQ1 as a Tool for Controlling Accelerated Senescence Program: Experiments with OXYS Rats. Biochemistry (Moscow) 87:12-13, pages 1552-1562.
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Yao Tong, Zunyi Zhang & Shusheng Wang. (2022) Role of Mitochondria in Retinal Pigment Epithelial Aging and Degeneration. Frontiers in Aging 3.
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Dan-Dan Chen, Xuyan Peng, Yuxuan Wang, Mingjun Jiang, Mengjiao Xue, Guohui Shang, Xuhui Liu, Xiaolin Jia, Baixue Liu, Yingwei Lu, Hongmei Mu, Fengyan Zhang & Yanzhong Hu. (2021) HSP90 acts as a senomorphic target in senescent retinal pigmental epithelial cells. Aging 13:17, pages 21547-21570.
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Mengling You, Rong Rong, Zhou Zeng, Haibo Li, Xiaobo Xia & Dan Ji. (2021) Single‐cell RNA sequencing: A new opportunity for retinal research . WIREs RNA 12:5.
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Andrea L. Blitzer, Sandra A. Ham, Kathryn A. Colby & Dimitra Skondra. (2021) Association of Metformin Use With Age-Related Macular Degeneration. JAMA Ophthalmology 139:3, pages 302.
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Д.В. Телегина, О.С. Кожевникова, А.Ж. Фурсова & Н.Г. Колосова. (2020) Аутофагия как мишень ретинопротекторного действия митохондриального антиоксиданта SkQ1. Биохимия 85:12, pages 1928-1938.
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D. V. Telegina, O. S. Kozhevnikova, A. Zh. Fursova & N. G. Kolosova. (2020) Autophagy as a Target for the Retinoprotective Effects of the Mitochondria-Targeted Antioxidant SkQ1. Biochemistry (Moscow) 85:12-13, pages 1640-1649.
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Anton G. Rogov, Tatyana N. Goleva, Evgeniya I. Sukhanova, Khoren K. Epremyan, Tatiana A. Trendeleva, Alexandra P. Ovchenkova, Dinara A. Aliverdieva & Renata A. Zvyagilskaya. (2020) Mitochondrial Dysfunctions May Be One of the Major Causative Factors Underlying Detrimental Effects of Benzalkonium Chloride. Oxidative Medicine and Cellular Longevity 2020, pages 1-14.
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Vasiliy A. Devyatkin, Olga E. Redina, Nataliya G. Kolosova & Natalia A. Muraleva. (2020) Single-Nucleotide Polymorphisms Associated with the Senescence-Accelerated Phenotype of OXYS Rats: A Focus on Alzheimer’s Disease-Like and Age-Related-Macular-Degeneration-Like Pathologies. Journal of Alzheimer's Disease 73:3, pages 1167-1183.
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Agnes Lipecz, Lauren Miller, Illes Kovacs, Cecília Czakó, Tamas Csipo, Judit Baffi, Anna Csiszar, Stefano Tarantini, Zoltan Ungvari, Andriy Yabluchanskiy & Shannon Conley. (2019) Microvascular contributions to age-related macular degeneration (AMD): from mechanisms of choriocapillaris aging to novel interventions. GeroScience 41:6, pages 813-845.
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Natalia A. Muraleva, Oyuna S. Kozhevnikova, Anzhela Z. Fursova & Nataliya G. Kolosova. (2019) Suppression of AMD-Like Pathology by Mitochondria-Targeted Antioxidant SkQ1 Is Associated with a Decrease in the Accumulation of Amyloid β and in mTOR Activity. Antioxidants 8:6, pages 177.
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Darya V. Telegina, Nataliya G. Kolosova & Oyuna S. Kozhevnikova. (2019) Immunohistochemical localization of NGF, BDNF, and their receptors in a normal and AMD-like rat retina. BMC Medical Genomics 12:S2.
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Nataliya G. Kolosova, Oyuna S. Kozhevnikova, Darya V. Telegina, Anzhela Zh. Fursova, Natalia A. Stefanova, Natalia A. Muraleva, Franco Venanzi, Michael Y. Sherman, Sergey I. Kolesnikov, Albert A. Sufianov, Vladimir L. Gabai & Alexander M. Shneider. (2018) p62 /SQSTM1 coding plasmid prevents age related macular degeneration in a rat model. Aging 10:8, pages 2136-2147.
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Oyuna S. Kozhevnikova, Darya V. Telegina, Vasiliy A. Devyatkin & Nataliya G. Kolosova. (2018) Involvement of the autophagic pathway in the progression of AMD-like retinopathy in senescence-accelerated OXYS rats. Biogerontology 19:3-4, pages 223-235.
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Boris A. Feniouk & Maxim V. Skulachev. 2018. Mitochondrial Biology and Experimental Therapeutics. Mitochondrial Biology and Experimental Therapeutics 637 645 .
Natalia A. Muraleva, Vasiliy A. Devyatkin & Nataliya G. Kolosova. (2017) Phosphorylation of αB-crystallin in the myocardium: Analysis of relations with aging and cardiomyopathy. Experimental Gerontology 95, pages 26-33.
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Mario Ost, Susanne Keipert & Susanne Klaus. (2017) Targeted mitochondrial uncoupling beyond UCP1 – The fine line between death and metabolic health. Biochimie 134, pages 77-85.
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Darya V. Telegina, Oyuna S. Kozhevnikova, Sergey I. Bayborodin & Nataliya G. Kolosova. (2017) Contributions of age-related alterations of the retinal pigment epithelium and of glia to the AMD-like pathology in OXYS rats. Scientific Reports 7:1.
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Ram Kannan, Parameswaran G. Sreekumar & David R. Hinton. (2016) Alpha crystallins in the retinal pigment epithelium and implications for the pathogenesis and treatment of age-related macular degeneration. Biochimica et Biophysica Acta (BBA) - General Subjects 1860:1, pages 258-268.
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Anton Petrov, Natalia Perekhvatova, Maxim Skulachev, Linda Stein & George Ousler. (2016) SkQ1 Ophthalmic Solution for Dry Eye Treatment: Results of a Phase 2 Safety and Efficacy Clinical Study in the Environment and During Challenge in the Controlled Adverse Environment Model. Advances in Therapy 33:1, pages 96-115.
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Rodrigue Rossignol. (2015) Energy metabolism disorders in rare and common diseases. Toward bioenergetic modulation therapy and the training of a new generation of European scientists. The International Journal of Biochemistry & Cell Biology 63, pages 2-9.
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