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Cell Cycle Volume 13, 2014 - Issue 22
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Inhibition of C-terminal binding protein attenuates transcription factor 4 signaling to selectively target colon cancer stem cells

Jagrut PatelHunter Holmes McGuire VA Medical Center; Richmond, VA USA
,
Somesh BaranwalDivision of Hematology; Oncology; and Palliative Care; Department of Internal Medicine; Virginia Commonwealth University; Richmond, VAUSA
,
Ian M LoveDivision of Hematology; Oncology; and Palliative Care; Department of Internal Medicine; Virginia Commonwealth University; Richmond, VAUSA
,
Nirmita J PatelHunter Holmes McGuire VA Medical Center; Richmond, VA USA
,
Steven R GrossmanDivision of Hematology; Oncology; and Palliative Care; Department of Internal Medicine; Virginia Commonwealth University; Richmond, VAUSA;VCU Massey Cancer Center; Virginia Commonwealth University; Richmond, VAUSA;Department of Human and Molecular Genetics; Virginia Commonwealth University, Richmond, VAUSA
&
Bhaumik B PatelHunter Holmes McGuire VA Medical Center; Richmond, VA USA;Division of Hematology; Oncology; and Palliative Care; Department of Internal Medicine; Virginia Commonwealth University; Richmond, VAUSA;VCU Massey Cancer Center; Virginia Commonwealth University; Richmond, VAUSACorrespondence[email protected]
Pages 3506-3518 | Received 24 Jun 2014, Accepted 21 Aug 2014, Published online: 10 Dec 2014

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M. Michael Dcona, Benjamin L. Morris, Keith C. Ellis & Steven R. Grossman. (2017) CtBP- an emerging oncogene and novel small molecule drug target: Advances in the understanding of its oncogenic action and identification of therapeutic inhibitors. Cancer Biology & Therapy 18:6, pages 379-391.
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Articles from other publishers (16)

Ravi Prakash Yadav & Somesh Baranwal. (2024) Kindlin-2 regulates colonic cancer stem-like cells survival and self-renewal via Wnt/β-catenin mediated pathway. Cellular Signalling 113, pages 110953.
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Di Wu, Wen Wu, Lan Tang, Xia Hu, Jing Zhang, Hanmei Li & Hui Li. (2022) Simulation-guided relationships and interaction characteristics of human CtBP1 in complex with protocatechualdehyde. Journal of Molecular Liquids 360, pages 119507.
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Linlin Fan, Xudong Yang, Minying Zheng, Xiaohui Yang, Yidi Ning, Ming Gao & Shiwu Zhang. (2022) Regulation of SUMOylation Targets Associated With Wnt/β-Catenin Pathway. Frontiers in Oncology 12.
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Weitao Zhang, Lu Kong, Hongbin Zhu, Decong Sun, Quanli Han, Bin Yan, Zhi Cui, Weiwei Zhang, Shurong Zhang, Xindan Kang, Guanghai Dai, Niansong Qian & Wenji Yan. (2022) Retinoic Acid-Induced 2 (RAI2) Is a Novel Antagonist of Wnt/β-Catenin Signaling Pathway and Potential Biomarker of Chemosensitivity in Colorectal Cancer. Frontiers in Oncology 12.
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Dávid Kis, Ilona Barbara Csordás, Eszter Persa, Bálint Jezsó, Rita Hargitai, Tünde Szatmári, Nikolett Sándor, Enikő Kis, Katalin Balázs, Géza Sáfrány & Katalin Lumniczky. (2022) Extracellular Vesicles Derived from Bone Marrow in an Early Stage of Ionizing Radiation Damage Are Able to Induce Bystander Responses in the Bone Marrow. Cells 11:1, pages 155.
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Zhi Chen. (2021) The transrepression and transactivation roles of CtBPs in the pathogenesis of different diseases. Journal of Molecular Medicine 99:10, pages 1335-1347.
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Bartolomeus J. Meijer, Wouter L. Smit, Pim J. Koelink, Barbara F. Westendorp, Ruben J. de Boer, Jonathan H. M. van der Meer, Jacqueline L. M. Vermeulen, James C. Paton, Adrienne W. Paton, Jun Qin, Evelien Dekker, Vanesa Muncan, Gijs R. van den Brink & Jarom Heijmans. (2021) Endoplasmic reticulum stress regulates the intestinal stem cell state through CtBP2. Scientific Reports 11:1.
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Yue-Wei Yin, Kai-Long Liu, Bao-Sai Lu, Wei Li, Ya-Lin Niu, Chen-Ming Zhao, Zhan Yang, Ping-Ying Guo & Jin-Chun Qi. (2021) RBM24 exacerbates bladder cancer progression by forming a Runx1t1/TCF4/miR-625-5p feedback loop. Experimental & Molecular Medicine 53:5, pages 933-946.
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Mira Kreuzer, Arindam Banerjee, Charles N. Birts, Matthew Darley, Ali Tavassoli, Mircea Ivan & Jeremy P. Blaydes. (2020) Glycolysis, via NADH‐dependent dimerisation of CtBPs, regulates hypoxia‐induced expression of CAIX and stem‐like breast cancer cell survival. FEBS Letters 594:18, pages 2988-3001.
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Christopher Gromisch, Motaz Qadan, Mariana Albuquerque Machado, Kebin Liu, Yolonda Colson & Mark W. Grinstaff. (2020) Pancreatic Adenocarcinoma: Unconventional Approaches for an Unconventional Disease. Cancer Research 80:16, pages 3179-3192.
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Ayesha T. Chawla, Agnes D. Cororaton, Michael O. Idowu, Priyadarshan K. Damle, Barbara Szomju, Keith C. Ellis, Bhaumik B. Patel & Steven R. Grossman. (2018) An intestinal stem cell niche in Apc mutated neoplasia targetable by CtBP inhibition . Oncotarget 9:65, pages 32408-32418.
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Xinghui Liu, Chengliang Zhu, Jie Li, Fengxia Xu, Gang Huang, Limin Xu & Binghong Zhang. (2018) HBV Upregulates CtBP2 Expression via the X Gene. BioMed Research International 2018, pages 1-6.
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Shriprakash Sinha. (2017) Hilbert-Schmidt and Sobol sensitivity indices for static and time series Wnt signaling measurements in colorectal cancer - part A. BMC Systems Biology 11:1.
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Melanie A. Blevins, Mingxia Huang & Rui Zhao. (2017) The Role of CtBP1 in Oncogenic Processes and Its Potential as a Therapeutic Target. Molecular Cancer Therapeutics 16:6, pages 981-990.
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Shirin R. Modarai, Lynn M. Opdenaker, Vignesh Viswanathan, Jeremy Z. Fields & Bruce M. Boman. (2016) Somatostatin signaling via SSTR1 contributes to the quiescence of colon cancer stem cells. BMC Cancer 16:1.
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Dusan Hrckulak, Michal Kolar, Hynek Strnad & Vladimir Korinek. (2016) TCF/LEF Transcription Factors: An Update from the Internet Resources. Cancers 8:7, pages 70.
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