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Cell Cycle Volume 14, 2015 - Issue 3
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Damage-induced BRCA1 phosphorylation by Chk2 contributes to the timing of end resection

Balaji ParameswaranDepartment of Molecular Medicine; University of Texas Health Science Center at San Antonio; San Antonio, TXUSA
,
Huai-Chin ChiangDepartment of Molecular Medicine; University of Texas Health Science Center at San Antonio; San Antonio, TXUSA
,
Yunzhe LuDepartment of Molecular Medicine; University of Texas Health Science Center at San Antonio; San Antonio, TXUSA
,
Julia CoatesThe Wellcome Trust and Cancer Research UK Gurdon Institute; and Department of Zoology; University of Cambridge; Cambridge, UK
,
Chu-Xia DengGenetics of Development and Disease Branch; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Health; Bethesda, MDUSA
,
Richard BaerInstitute for Cancer Genetics; Department of Pathology; Columbia University; New York, NYUSA
,
Hui-Kuan LinDepartment of Molecular and Cellular Oncology; The University of Texas MD Anderson Cancer Center; Houston, TX USA
,
Rong LiDepartment of Molecular Medicine; University of Texas Health Science Center at San Antonio; San Antonio, TXUSA
,
Tanya T PaullDepartment of Molecular Genetics and Microbiology; University of Texas; Austin, TXUSA
&
Yanfen HuDepartment of Molecular Medicine; University of Texas Health Science Center at San Antonio; San Antonio, TXUSACorrespondence[email protected]
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Pages 437-448 | Received 18 Jul 2014, Accepted 30 Sep 2014, Published online: 06 Feb 2015

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Wenwen Zhang, Lulu Cao, Zijia Sun, Jing Xu, Lin Tang, Weiwei Chen, Jiayan Luo, Fang Yang, Yucai Wang & Xiaoxiang Guan. (2016) Skp2 is over-expressed in breast cancer and promotes breast cancer cell proliferation. Cell Cycle 15:10, pages 1344-1351.
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Articles from other publishers (26)

Chao Liu, Shuwen Kuang, Lei Wu, Quan Cheng, Xuan Gong, Jun Wu & Longbo Zhang. (2023) Radiotherapy and radio‐sensitization in H3 K27M ‐mutated diffuse midline gliomas . CNS Neuroscience & Therapeutics 29:7, pages 1721-1737.
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Leilei Qi, Reka Chakravarthy, Monica M. Li, Chu-Xia Deng, Rong Li & Yanfen Hu. (2022) Phosphorylation of BRCA1 by ATM upon double-strand breaks impacts ATM function in end-resection: A potential feedback loop. iScience 25:9, pages 104944.
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Dongju Park, Mehdi Gharghabi, Colleen R. Reczek, Rebecca Plow, Charles Yungvirt, C. Marcelo Aldaz & Kay Huebner. (2022) Wwox Binding to the Murine Brca1-BRCT Domain Regulates Timing of Brip1 and CtIP Phospho-Protein Interactions with This Domain at DNA Double-Strand Breaks, and Repair Pathway Choice. International Journal of Molecular Sciences 23:7, pages 3729.
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Rick A.C.M. Boonen, Wouter W. Wiegant, Nandi Celosse, Bas Vroling, Stephan Heijl, Zsofia Kote-Jarai, Martina Mijuskovic, Simona Cristea, Nienke Solleveld-Westerink, Tom van Wezel, Niko Beerenwinkel, Rosalind Eeles, Peter Devilee, Maaike P.G. Vreeswijk, Giancarlo Marra & Haico van Attikum. (2022) Functional Analysis Identifies Damaging CHEK2 Missense Variants Associated with Increased Cancer Risk . Cancer Research 82:4, pages 615-631.
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José Antonio Pedroza‐Garcia, Yanli Xiang & Lieven De Veylder. (2021) Cell cycle checkpoint control in response to DNA damage by environmental stresses. The Plant Journal 109:3, pages 490-507.
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Dongju Park, Mehdi Gharghabi, Morgan S. Schrock, Rebecca Plow, Teresa Druck, Charles Yungvirt, C. Marcelo Aldaz & Kay Huebner. (2022) Interaction of Wwox with Brca1 and associated complex proteins prevents premature resection at double-strand breaks and aberrant homologous recombination. DNA Repair 110, pages 103264.
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Jae Jin Kim, Seo Yun Lee, Yiseul Hwang, Soyeon Kim, Jee Min Chung, Sangwook Park, Junghyun Yoon, Hansol Yun, Jae-Hoon Ji, Sunyoung Chae, Hyeseong Cho, Chan Gil Kim, Ted M Dawson, Hongtae Kim, Valina L Dawson & Ho Chul Kang. (2021) USP39 promotes non-homologous end-joining repair by poly(ADP-ribose)-induced liquid demixing. Nucleic Acids Research 49:19, pages 11083-11102.
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Caroline Molinaro, Alain Martoriati & Katia Cailliau. (2021) Proteins from the DNA Damage Response: Regulation, Dysfunction, and Anticancer Strategies. Cancers 13:15, pages 3819.
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Talia Golan, Grainne M. O’Kane, Robert E. Denroche, Maria Raitses-Gurevich, Robert C. Grant, Spring Holter, Yifan Wang, Amy Zhang, Gun Ho Jang, Chani Stossel, Dikla Atias, Sharon Halperin, Raanan Berger, Yulia Glick, J. Patrick Park, Adeline Cuggia, Laura Williamson, Hui-Li Wong, David F. Schaeffer, Daniel J. Renouf, Ayelet Borgida, Anna Dodd, Julie M. Wilson, Sandra E. Fischer, Faiyaz Notta, Jennifer J. Knox, George Zogopoulos & Steven Gallinger. (2021) Genomic Features and Classification of Homologous Recombination Deficient Pancreatic Ductal Adenocarcinoma. Gastroenterology 160:6, pages 2119-2132.e9.
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Rayhaan M. M. Ali, Stuart A. McIntosh & Kienan I. Savage. (2020) Homologous recombination deficiency in breast cancer: Implications for risk, cancer development, and therapy. Genes, Chromosomes and Cancer 60:5, pages 358-372.
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Man-Li Luo, Fang Zheng, Wenying Chen, Zhi-Mei Liang, Gurushankar Chandramouly, Jianan Tan, Nicholas A. Willis, Chun-Hau Chen, Mateus de Oliveira Taveira, Xiao Zhen Zhou, Kun Ping Lu, Ralph Scully, Gerburg M. Wulf & Hai Hu. (2020) Inactivation of the Prolyl Isomerase Pin1 Sensitizes BRCA1-Proficient Breast Cancer to PARP Inhibition. Cancer Research 80:14, pages 3033-3045.
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Martina Rama & Benjamin Bonavida. 2020. Prognostic and Therapeutic Applications of RKIP in Cancer. Prognostic and Therapeutic Applications of RKIP in Cancer 175 209 .
Jaana van Gastel, Hanne Leysen, Paula Santos-Otte, Jhana O. Hendrickx, Abdelkrim Azmi, Bronwen Martin & Stuart Maudsley. (2019) The RXFP3 receptor is functionally associated with cellular responses to oxidative stress and DNA damage. Aging 11:23, pages 11268-11313.
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Beril Tutuncuoglu & Nevan J. Krogan. (2019) Mapping genetic interactions in cancer: a road to rational combination therapies. Genome Medicine 11:1.
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Ádám Póti, Hella Gyergyák, Eszter Németh, Orsolya Rusz, Szilárd Tóth, Csenger Kovácsházi, Dan Chen, Bernadett Szikriszt, Sándor Spisák, Shunichi Takeda, Gergely Szakács, Zoltan Szallasi, Andrea L. Richardson & Dávid Szüts. (2019) Correlation of homologous recombination deficiency induced mutational signatures with sensitivity to PARP inhibitors and cytotoxic agents. Genome Biology 20:1.
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Gayathri SrinivasanElizabeth A. WilliamsonKimi KongAruna S. JaiswalGuangcun HuangHyun-Suk KimOrlando SchärerWeixing ZhaoSandeep Burma, Patrick SungRobert Hromas. (2019) MiR223-3p promotes synthetic lethality in BRCA1-deficient cancers. Proceedings of the National Academy of Sciences 116:35, pages 17438-17443.
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Jing An, Huixin He, Lu Wang, Yingying Jin, Jiexing Kong, Yufang Zhong, Mingyuan Liu & Yu Shang. (2019) Fresh and ozonized black carbon promoted DNA damage and repair responses in A549 cells. Toxicology Research 8:2, pages 180-187.
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Debjani Pal & Matthew K. Summers. 2018. Ubiquitination Governing DNA Repair - Implications in Health and Disease. Ubiquitination Governing DNA Repair - Implications in Health and Disease.
Charlotte Trussart, Céline Pirlot, Emmanuel Di Valentin, Jacques Piette & Yvette Habraken. (2018) Melanoma antigen-D2 controls cell cycle progression and modulates the DNA damage response. Biochemical Pharmacology 153, pages 217-229.
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Rachel Reichman, Zhuoyue Shi, Robert Malone & Sarit Smolikove. (2018) Mitotic and Meiotic Functions for the SUMOylation Pathway in the Caenorhabditis elegans Germline . Genetics 208:4, pages 1421-1441.
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Nozomi Tomimatsu, Bipasha Mukherjee, Janelle Louise Harris, Francesca Ludovica Boffo, Molly Catherine Hardebeck, Patrick Ryan Potts, Kum Kum Khanna & Sandeep Burma. (2017) DNA-damage-induced degradation of EXO1 exonuclease limits DNA end resection to ensure accurate DNA repair. Journal of Biological Chemistry 292:26, pages 10779-10790.
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David Lopez-Martinez, Chih-Chao Liang & Martin A. Cohn. (2016) Cellular response to DNA interstrand crosslinks: the Fanconi anemia pathway. Cellular and Molecular Life Sciences 73:16, pages 3097-3114.
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Sreejith J. Nair, Xiaowen Zhang, Huai-Chin Chiang, Md Jamiul Jahid, Yao Wang, Paula Garza, Craig April, Neeraj Salathia, Tapahsama Banerjee, Fahad S. Alenazi, Jianhua Ruan, Jian-Bing Fan, Jeffrey D. Parvin, Victor X. Jin, Yanfen Hu & Rong Li. (2016) Genetic suppression reveals DNA repair-independent antagonism between BRCA1 and COBRA1 in mammary gland development. Nature Communications 7:1.
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Jinho Heo, Rebeka Eki & Tarek Abbas. (2016) Deregulation of F-box proteins and its consequence on cancer development, progression and metastasis. Seminars in Cancer Biology 36, pages 33-51.
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Rosa Pennisi, Paolo Ascenzi & Alessandra di Masi. (2015) Hsp90: A New Player in DNA Repair?. Biomolecules 5:4, pages 2589-2618.
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Huai-Chin ChiangRichard ElledgePaula LarsonIsmail JatoiRong LiYanfen Hu. (2015) Effects of Radiation Therapy on Breast Epithelial Cells in BRCA1/2 Mutation Carriers . Breast Cancer: Basic and Clinical Research 9, pages BCBCR.S26774.
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