3,781
Views
54
CrossRef citations to date
0
Altmetric
REVIEW

Modify or die? - RNA modification defects in metazoans

&
Pages 1555-1567 | Received 30 Jun 2014, Accepted 10 Nov 2014, Published online: 26 Feb 2015

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Nicky Jonkhout, Sonia Cruciani, Helaine Graziele Santos Vieira, Julia Tran, Huanle Liu, Ganqiang Liu, Russell Pickford, Dominik Kaczorowski, Gloria R. Franco, Franz Vauti, Noelia Camacho, Seyedeh Sedigheh Abedini, Hossein Najmabadi, Lluís Ribas de Pouplana, Daniel Christ, Nicole Schonrock, John S. Mattick & Eva Maria Novoa. (2021) Subcellular relocalization and nuclear redistribution of the RNA methyltransferases TRMT1 and TRMT1L upon neuronal activation. RNA Biology 18:11, pages 1905-1919.
Read now
Jo Marie Bacusmo, Silvia S. Orsini, Jennifer Hu, Michael DeMott, Patrick C. Thiaville, Ameer Elfarash, Mellie June Paulines, Diego Rojas-Benítez, Birthe Meineke, Chris Deutsch, Dirk Iwata-Reuyl, Patrick A. Limbach, Peter C. Dedon, Kelly C. Rice, Stewart Shuman & Valérie de Crécy-Lagard. (2018) The t6A modification acts as a positive determinant for the anticodon nuclease PrrC, and is distinctively nonessential in Streptococcus mutans . RNA Biology 15:4-5, pages 508-517.
Read now
Joshua M. Dewe, Benjamin L. Fuller, Jenna M. Lentini, Stefanie M. Kellner & Dragony Fu. (2017) TRMT1-Catalyzed tRNA Modifications Are Required for Redox Homeostasis To Ensure Proper Cellular Proliferation and Oxidative Stress Survival. Molecular and Cellular Biology 37:21.
Read now
Raffael Schaffrath & Sebastian A. Leidel. (2017) Wobble uridine modifications–a reason to live, a reason to die?!. RNA Biology 14:9, pages 1209-1222.
Read now

Articles from other publishers (50)

Fiona Alings, Karin Scharmann, Cristian Eggers, Bettina Böttcher, Mikołaj Sokołowski, Ekaterina Shvetsova, Puneet Sharma, Joël Roth, Leon Rashiti, Sebastian Glatt, Sascha Brunke & Sebastian A Leidel. (2023) Ncs2* mediates in vivo virulence of pathogenic yeast through sulphur modification of cytoplasmic transfer RNA . Nucleic Acids Research.
Crossref
Yan-Yue Wang, Yuan Tian, Yong-Zhen Li, Yi-Fan Liu, Yu-Yan Zhao, Lin-Hui Chen & Chi Zhang. (2023) The role of m5C methyltransferases in cardiovascular diseases. Frontiers in Cardiovascular Medicine 10.
Crossref
Yu-shan Chen, Jing Dong, Wei Tan, Hui Liu, Si-ming Zhang, Jia Zou, Yi-qi Chen, Shu-yan Bai & Yan Zeng. (2023) The potential role of ribonucleic acid methylation in the pathological mechanisms of fragile X syndrome. Behavioural Brain Research, pages 114586.
Crossref
Junya Lv, Lijuan Xing, Xin Zhong, Kai Li, Mingyan Liu & Ke Du. (2023) Role of N6-methyladenosine modification in central nervous system diseases and related therapeutic agents. Biomedicine & Pharmacotherapy 162, pages 114583.
Crossref
Timothy Balmorez, Amy Sakazaki & Shin Murakami. (2023) Genetic Networks of Alzheimer’s Disease, Aging, and Longevity in Humans. International Journal of Molecular Sciences 24:6, pages 5178.
Crossref
Hongmiao Tao, Lihua Dong & Lin Li. (2022) N6-methyladenosine modulation classes and immune microenvironment regulation in ischemic stroke. Frontiers in Molecular Neuroscience 15.
Crossref
Olubodun Michael Lateef, Michael Olawale Akintubosun, Olamide Tosin Olaoba, Sunday Ocholi Samson & Malgorzata Adamczyk. (2022) Making Sense of “Nonsense” and More: Challenges and Opportunities in the Genetic Code Expansion, in the World of tRNA Modifications. International Journal of Molecular Sciences 23:2, pages 938.
Crossref
Marc Graille. (2021) Division of labor in epitranscriptomics: What have we learnt from the structures of eukaryotic and viral multimeric RNA methyltransferases? . WIREs RNA 13:1.
Crossref
Markus Hillmeier, Mirko Wagner, Timm Ensfelder, Eva Korytiakova, Peter Thumbs, Markus Müller & Thomas Carell. (2021) Synthesis and structure elucidation of the human tRNA nucleoside mannosyl-queuosine. Nature Communications 12:1.
Crossref
Xiaohua Yi, Shuai He, Shuhui Wang, Haidong Zhao, Mingli Wu, Shirong Liu & Xiuzhu Sun. (2021) Detection of genetic variation and activity analysis of the promoter region of the cattle tRNA-modified gene <i>TRDMT1</i>. Archives Animal Breeding 64:1, pages 147-155.
Crossref
Martin Termathe & Sebastian A. Leidel. (2021) Urm1: A Non-Canonical UBL. Biomolecules 11:2, pages 139.
Crossref
Oguzhan Begik, Morghan C. Lucas, Huanle Liu, Jose Miguel Ramirez, John S. Mattick & Eva Maria Novoa. (2020) Integrative analyses of the RNA modification machinery reveal tissue- and cancer-specific signatures. Genome Biology 21:1.
Crossref
Diana Andrea Fernandes De Abreu, Thalia Salinas-Giegé, Laurence Drouard & Jean-Jacques Remy. (2020) Alanine tRNAs Translate Environment Into Behavior in Caenorhabditis elegans. Frontiers in Cell and Developmental Biology 8.
Crossref
Joshua A Arribere, Hidehito Kuroyanagi & Heather A Hundley. (2020) mRNA Editing, Processing and Quality Control in Caenorhabditis elegans . Genetics 215:3, pages 531-568.
Crossref
Carole Trzaska, Séverine Amand, Christine Bailly, Catherine Leroy, Virginie Marchand, Evelyne Duvernois-Berthet, Jean-Michel Saliou, Hana Benhabiles, Elisabeth Werkmeister, Thierry Chassat, Romain Guilbert, David Hannebique, Anthony Mouray, Marie-Christine Copin, Pierre-Arthur Moreau, Eric Adriaenssens, Andreas Kulozik, Eric Westhof, David Tulasne, Yuri Motorin, Sylvie Rebuffat & Fabrice Lejeune. (2020) 2,6-Diaminopurine as a highly potent corrector of UGA nonsense mutations. Nature Communications 11:1.
Crossref
Britta Meyer, Carina Immer, Steffen Kaiser, Sunny Sharma, Jun Yang, Peter Watzinger, Lena Weiß, Annika Kotter, Mark Helm, Hans-Michael Seitz, Peter Kötter, Stefanie Kellner, Karl-Dieter Entian & Jens Wöhnert. (2020) Identification of the 3-amino-3-carboxypropyl (acp) transferase enzyme responsible for acp3U formation at position 47 in Escherichia coli tRNAs. Nucleic Acids Research 48:3, pages 1435-1450.
Crossref
Diego Rojas-Benítez & Miguel L. Allende. (2020) Elongator Subunit 3 (Elp3) Is Required for Zebrafish Trunk Development. International Journal of Molecular Sciences 21:3, pages 925.
Crossref
Huanle Liu, Oguzhan Begik, Morghan C. Lucas, Jose Miguel Ramirez, Christopher E. Mason, David Wiener, Schraga Schwartz, John S. Mattick, Martin A. Smith & Eva Maria Novoa. (2019) Accurate detection of m6A RNA modifications in native RNA sequences. Nature Communications 10:1.
Crossref
Pauline Mosca, Bruno Leheup & Natacha Dreumont. (2019) Nutrigenomics and RNA methylation: Role of micronutrients. Biochimie 164, pages 53-59.
Crossref
Namit Ranjan & Sebastian A. Leidel. (2019) The epitranscriptome in translation regulation: mRNA and tRNA modifications as the two sides of the same coin? . FEBS Letters 593:13, pages 1483-1493.
Crossref
Martin Müller, Carine Legrand, Francesca Tuorto, Vincent P Kelly, Yaser Atlasi, Frank Lyko & Ann E Ehrenhofer-Murray. (2019) Queuine links translational control in eukaryotes to a micronutrient from bacteria. Nucleic Acids Research 47:7, pages 3711-3727.
Crossref
Sabrina Huber, Andrea Leonardi, Peter Dedon & Thomas Begley. (2019) The Versatile Roles of the tRNA Epitranscriptome during Cellular Responses to Toxic Exposures and Environmental Stress. Toxics 7:1, pages 17.
Crossref
Valérie de Crécy-Lagard, Pietro Boccaletto, Carl G Mangleburg, Puneet Sharma, Todd M Lowe, Sebastian A Leidel & Janusz M Bujnicki. (2019) Matching tRNA modifications in humans to their known and predicted enzymes. Nucleic Acids Research 47:5, pages 2143-2159.
Crossref
Ya-Ming Hou, Isao Masuda & Howard Gamper. (2019) Codon-Specific Translation by m1G37 Methylation of tRNA. Frontiers in Genetics 9.
Crossref
Adeline Galvanin, Lilia Ayadi, Mark Helm, Yuri Motorin & Virginie Marchand. 2019. Epitranscriptomics. Epitranscriptomics 273 295 .
Virginie Marchand, Lilia Ayadi, Felix G. M. Ernst, Jasmin Hertler, Valérie Bourguignon‐Igel, Adeline Galvanin, Annika Kotter, Mark Helm, Denis L. J. Lafontaine & Yuri Motorin. (2018) AlkAniline‐Seq: Profiling of m 7 G and m 3 C RNA Modifications at Single Nucleotide Resolution . Angewandte Chemie International Edition 57:51, pages 16785-16790.
Crossref
Virginie Marchand, Lilia Ayadi, Felix G. M. Ernst, Jasmin Hertler, Valérie Bourguignon‐Igel, Adeline Galvanin, Annika Kotter, Mark Helm, Denis L. J. Lafontaine & Yuri Motorin. (2018) AlkAniline‐Seq: Profiling of m 7 G and m 3 C RNA Modifications at Single Nucleotide Resolution . Angewandte Chemie 130:51, pages 17027-17032.
Crossref
Vera Oberbauer & Matthias Schaefer. (2018) tRNA-Derived Small RNAs: Biogenesis, Modification, Function and Potential Impact on Human Disease Development. Genes 9:12, pages 607.
Crossref
Andrew J Fisher & Peter A Beal. (2018) Structural basis for eukaryotic mRNA modification. Current Opinion in Structural Biology 53, pages 59-68.
Crossref
L. Peter Sarin, Sandra D. Kienast, Johannes Leufken, Robert L. Ross, Agnieszka Dziergowska, Katarzyna Debiec, Elzbieta Sochacka, Patrick A. Limbach, Christian Fufezan, Hannes C.A. Drexler & Sebastian A. Leidel. (2018) Nano LC-MS using capillary columns enables accurate quantification of modified ribonucleosides at low femtomol levels. RNA 24:10, pages 1403-1417.
Crossref
Manasses Jora, Congliang Sun, Patrick A. Limbach & Balasubrahmanyam Addepalli. (2018) Global Profiling of the Oxidative Stress Induced Effects on RNA Modifications by Liquid Chromatography‐Tandem Mass Spectrometry. The FASEB Journal 32:S1.
Crossref
Anne Hoffmann, Jörg Fallmann, Elisa Vilardo, Mario Mörl, Peter F Stadler & Fabian Amman. (2018) Accurate mapping of tRNA reads. Bioinformatics 34:7, pages 1116-1124.
Crossref
Cha San Koh & L. Peter Sarin. (2018) Transfer RNA modification and infection – Implications for pathogenicity and host responses. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1861:4, pages 419-432.
Crossref
Mikołaj Sokołowski, Roland Klassen, Alexander Bruch, Raffael Schaffrath & Sebastian Glatt. (2018) Cooperativity between different tRNA modifications and their modification pathways. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1861:4, pages 409-418.
Crossref
Maria I. Dauden, Marcin Jaciuk, Christoph W. Müller & Sebastian Glatt. (2017) Structural asymmetry in the eukaryotic Elongator complex. FEBS Letters 592:4, pages 502-515.
Crossref
Pierre Close, Debojit Bose, Alain Chariot & Sebastian A. Leidel. 2018. Cancer and Noncoding RNAs. Cancer and Noncoding RNAs 163 186 .
Nicky Jonkhout, Julia Tran, Martin A. Smith, Nicole Schonrock, John S. Mattick & Eva Maria Novoa. (2017) The RNA modification landscape in human disease. RNA 23:12, pages 1754-1769.
Crossref
Mónica Marín, Tamara Fernández-Calero & Ricardo Ehrlich. (2017) Protein folding and tRNA biology. Biophysical Reviews 9:5, pages 573-588.
Crossref
Heidelinde Glasner, Christian Riml, Ronald Micura & Kathrin Breuker. (2017) Label-free, direct localization and relative quantitation of the RNA nucleobase methylations m6A, m5C, m3U, and m5U by top-down mass spectrometry. Nucleic Acids Research 45:13, pages 8014-8025.
Crossref
Xushen Xiong, Chengqi Yi & Jinying Peng. (2017) Epitranscriptomics: Toward A Better Understanding of RNA Modifications. Genomics, Proteomics & Bioinformatics 15:3, pages 147-153.
Crossref
Matthias Schaefer, Utkarsh Kapoor & Michael F. Jantsch. (2017) Understanding RNA modifications: the promises and technological bottlenecks of the ‘epitranscriptome’. Open Biology 7:5, pages 170077.
Crossref
Anna GebhardtBeatrice T. LaudenbachAndreas Pichlmair. (2017) Discrimination of Self and Non-Self Ribonucleic Acids. Journal of Interferon & Cytokine Research 37:5, pages 184-197.
Crossref
Simon Edvardson, Laurence Prunetti, Aiman Arraf, Drago Haas, Jo Marie Bacusmo, Jennifer F Hu, Asas Ta-Shma, Peter C Dedon, Valérie de Crécy-Lagard & Orly Elpeleg. (2017) tRNA N6-adenosine threonylcarbamoyltransferase defect due to KAE1/TCS3 (OSGEP) mutation manifest by neurodegeneration and renal tubulopathy. European Journal of Human Genetics 25:5, pages 545-551.
Crossref
Valentin F. Reichle & Stefanie Kellner. (2017) Biochemie 2016: Der Einfluss des Epitranskriptoms auf Krankheiten und dessen Analytik. Nachrichten aus der Chemie 65:3, pages 316-320.
Crossref
Virginie Marchand, Florian Pichot, Kathrin Thüring, Lilia Ayadi, Isabel Freund, Alexander Dalpke, Mark Helm & Yuri Motorin. (2017) Next‐Generation Sequencing‐Based RiboMethSeq Protocol for Analysis of tRNA 2′‐O‐Methylation. Biomolecules 7:4, pages 13.
Crossref
Tamara Fernández-Calero, Florencia Cabrera-Cabrera, Ricardo Ehrlich & Mónica Marín. (2016) Silent Polymorphisms: Can the tRNA Population Explain Changes in Protein Properties?. Life 6:1, pages 9.
Crossref
Thomas Philipp Hoernes, Nina Clementi, Klaus Faserl, Heidelinde Glasner, Kathrin Breuker, Herbert Lindner, Alexander Hüttenhofer & Matthias David Erlacher. (2016) Nucleotide modifications within bacterial messenger RNAs regulate their translation and are able to rewire the genetic code. Nucleic Acids Research 44:2, pages 852-862.
Crossref
Martyna C. Popis, Sandra Blanco & Michaela Frye. (2016) Posttranscriptional methylation of transfer and ribosomal RNA in stress response pathways, cell differentiation, and cancer. Current Opinion in Oncology 28:1, pages 65-71.
Crossref
Shawn M. Lyons, Marta M. Fay & Pavel Ivanov. 2016. Modified Nucleic Acids in Biology and Medicine. Modified Nucleic Acids in Biology and Medicine 27 54 .
Diana Andrea Fernandes De Abreu, Thalia Salinas-Gieg&eacute;Laurence Mar&eacute;chal-Drouard & Jean-Jacques Remy. (2019) Alanine tRNA Translate Environment into Behavior in <i>Caenorhabditis Elegans</i>. SSRN Electronic Journal.
Crossref