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Jerome H. Check & Diane L. Check. (2023) The role of progesterone and the progesterone receptor in cancer: progress in the last 5 years. Expert Review of Endocrinology & Metabolism 18:1, pages 5-18.
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Jian Wu, Simon Michaeli, Lorenzo Picchianti, Yasin Dagdas, Gad Galili & Hadas Peled-Zehavi. (2021) ATI1 (ATG8-interacting protein 1) and ATI2 define a plant starvation-induced reticulophagy pathway and serve as MSBP1/MAPR5 cargo receptors. Autophagy 17:11, pages 3375-3388.
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Faheem, Banoth Karan Kumar, Kondapalli Venkata Gowri Chandra Sekhar, Subhash Chander, Selvaraj Kunjiappan & Sankaranarayanan Murugesan. (2021) 1,2,3,4-Tetrahydroisoquinoline (THIQ) as privileged scaffold for anticancer de novo drug design. Expert Opinion on Drug Discovery 16:10, pages 1119-1147.
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Articles from other publishers (55)
Kayhan Yakin, Francesko Hela & Ozgur Oktem. (2023) Progesterone signaling in the regulation of luteal steroidogenesis. Molecular Human Reproduction 29:8.
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ZhenYu Zhu, Ting Cao, Hui Chen, BiKui Zhang, ChenQuan Lin & HuaLin Cai. (2023) Olanzapine-induced nonalcoholic fatty liver disease: The effects of differential food pattern and the involvement of PGRMC1 signaling. Food and Chemical Toxicology 176, pages 113757.
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Britney N. Lizama, Jennifer Kahle, Susan M. Catalano, Anthony O. Caggiano, Michael Grundman & Mary E. Hamby. (2023) Sigma-2 Receptors—From Basic Biology to Therapeutic Target: A Focus on Age-Related Degenerative Diseases. International Journal of Molecular Sciences 24:7, pages 6251.
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Yuanyao Chen, Lin Xiao, Jia Xu, Jingming Wang, Zhiquan Yu, Kai Zhao, Huiping Zhang, Shibin Cheng, Surendra Sharma, Aihua Liao & Chunyan Liu. (2023) Recent insight into autophagy and immunity at the maternal-fetal interface. Journal of Reproductive Immunology 155, pages 103781.
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Dora Maria Velázquez Hernández, Edgar Ricardo Vázquez-Martínez & Ignacio Camacho-Arroyo. (2022) The role of progesterone receptor membrane component (PGRMC) in the endometrium. Steroids 184, pages 109040.
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James K Pru. (2022) Pleiotropic Actions of PGRMC Proteins in Cancer. Endocrinology 163:7.
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Solaipriya Solairaja, Satish Ramalingam, Nageswara Rao Dunna & Sivaramakrishnan Venkatabalasubramanian. (2022) Progesterone Receptor Membrane Component 1 and its Accomplice:
Emerging Therapeutic Targets in Lung Cancer. Endocrine, Metabolic & Immune Disorders - Drug Targets 22:6, pages 601-611.
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Susan Catalano. 2022. Alzheimer's Disease Drug Development. Alzheimer's Disease Drug Development
513
523
.
Ying He, Xun-Hu Dong, Qiong Zhu, Ya-Li Xu, Ming-Liang Chen & Zheng Liu. (2022) Ultrasound-triggered microbubble destruction enhances the radiosensitivity of glioblastoma by inhibiting PGRMC1-mediated autophagy in vitro and in vivo. Military Medical Research 9:1.
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Sang Kwon Lee, Yeong Cheon Kweon, Ah Reum Lee, Yoon Young Lee & Chan Young Park. (2022) Metastasis enhancer PGRMC1 boosts store-operated Ca2+ entry by uncoiling Ca2+ sensor STIM1 for focal adhesion turnover and actomyosin formation. Cell Reports 38:3, pages 110281.
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Ji Hyeon You, Jaewang Lee & Jong-Lyel Roh. (2021) PGRMC1-dependent lipophagy promotes ferroptosis in paclitaxel-tolerant persister cancer cells. Journal of Experimental & Clinical Cancer Research 40:1.
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Megan E. Rosa‐Caldwell, Marie Mortreux, Ursula B. Kaiser, Dong‐Min Sung, Mary L. Bouxsein, Kirsten R. Dunlap, Nicholas P. Greene & Seward B. Rutkove. (2021) The oestrous cycle and skeletal muscle atrophy: Investigations in rodent models of muscle loss. Experimental Physiology 106:12, pages 2472-2488.
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Meredith R. McGuire, Debaditya Mukhopadhyay, Stephanie L. Myers, Eric P. Mosher, Rita T. Brookheart, Kai Kammers, Alfica Sehgal, Ebru S. Selen, Michael J. Wolfgang, Namandjé N. Bumpus & Peter J. Espenshade. (2021) Progesterone receptor membrane component 1 (PGRMC1) binds and stabilizes cytochromes P450 through a heme-independent mechanism. Journal of Biological Chemistry 297:5, pages 101316.
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Meijian Wang, Min Xie, Shuyan Yu, Pan Shang, Cong Zhang, Xiaolin Han, Cuiqin Fan, Li Chen, Xianghua Zhuang & Shihong Chen. (2021) Lipin1 Alleviates Autophagy Disorder in Sciatic Nerve and Improves Diabetic Peripheral Neuropathy. Molecular Neurobiology 58:11, pages 6049-6061.
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Yu-Jie Chen, Jeffrey Knupp, Anoop Arunagiri, Leena Haataja, Peter Arvan & Billy Tsai. (2021) PGRMC1 acts as a size-selective cargo receptor to drive ER-phagic clearance of mutant prohormones. Nature Communications 12:1.
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Stefania Salsano, Roberto González-Martín, Alicia Quiñonero, Silvia Pérez-Debén & Francisco Domínguez. (2021) Deciphering the Role of PGRMC1 During Human Decidualization Using an In Vitro Approach. The Journal of Clinical Endocrinology & Metabolism 106:8, pages 2313-2327.
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Colleen S. Limegrover, Raymond Yurko, Nicholas J. Izzo, Kelsie M. LaBarbera, Courtney Rehak, Gary Look, Gilbert Rishton, Hank Safferstein & Susan M. Catalano. (2021) Sigma‐2 receptor antagonists rescue neuronal dysfunction induced by Parkinson’s patient brain‐derived α‐synuclein. Journal of Neuroscience Research 99:4, pages 1161-1176.
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Kai Yang, Cheng Zeng, Changcai Wang, Meng Sun, Dan Yin & Taolei Sun. (2020) Sigma-2 Receptor—A Potential Target for Cancer/Alzheimer’s Disease Treatment via Its Regulation of Cholesterol Homeostasis. Molecules 25:22, pages 5439.
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Amir Ajoolabady, Hamid Aslkhodapasandhokmabad, Ayuob Aghanejad, Yingmei Zhang & Jun Ren. (2020) Mitophagy Receptors and Mediators: Therapeutic Targets in the Management of Cardiovascular Ageing. Ageing Research Reviews 62, pages 101129.
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Claudia Espinosa-Garcia, Fahim Atif, Seema Yousuf, Iqbal Sayeed, Gretchen N. Neigh & Donald G. Stein. (2020) Progesterone Attenuates Stress-Induced NLRP3 Inflammasome Activation and Enhances Autophagy Following Ischemic Brain Injury. International Journal of Molecular Sciences 21:11, pages 3740.
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Stefania Salsano, Roberto González-Martín, Alicia Quiñonero, Soraya López-Martín, Ana Pilar Gómez-Escribano, Silvia Pérez-Debén, Maria Yañez-Mo & Francisco Domínguez. (2020) Novel nonclassic progesterone receptor PGRMC1 pulldown-precipitated proteins reveal a key role during human decidualization. Fertility and Sterility 113:5, pages 1050-1066.e7.
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Susana L. González, María F. Coronel, María C. Raggio & Florencia Labombarda. (2020) Progesterone receptor-mediated actions and the treatment of central nervous system disorders: An up-date of the known and the challenge of the unknown. Steroids 153, pages 108525.
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Barbara Del Bello, Paola Marcolongo, Pasquapina Ciarmela, Flavia Sorbi, Felice Petraglia, Stefano Luisi & Emilia Maellaro. (2019) Autophagy up-regulation by ulipristal acetate as a novel target mechanism in the treatment of uterine leiomyoma: an in vitro study. Fertility and Sterility 112:6, pages 1150-1159.
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Robert B. PielIIIIII, Harry A. DaileyJr.Jr. & Amy E. Medlock. (2019) The mitochondrial heme metabolon: Insights into the complex(ity) of heme synthesis and distribution. Molecular Genetics and Metabolism 128:3, pages 198-203.
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Domenica Roberto, Shamini Selvarajah, Paul C. Park, David Berman & Vasundara Venkateswaran. (2019) Functional validation of metabolic genes that distinguish Gleason 3 from Gleason 4 prostate cancer foci. The Prostate 79:15, pages 1777-1788.
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Iredia D. Iyamu, Wei Lv, Neha Malik, Rama K. Mishra & Gary E. Schiltz. (2019) Development of Tetrahydroindazole‐Based Potent and Selective Sigma‐2 Receptor Ligands. ChemMedChem 14:13, pages 1248-1256.
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Mohammad Golam Sabbir. (2019) Progesterone induced Warburg effect in HEK293 cells is associated with post-translational modifications and proteasomal degradation of progesterone receptor membrane component 1. The Journal of Steroid Biochemistry and Molecular Biology 191, pages 105376.
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Anna Tesei, Michela Cortesi, Sara Pignatta, Chiara Arienti, Giulio Massimo Dondio, Chiara Bigogno, Alessio Malacrida, Mariarosaria Miloso, Cristina Meregalli, Alessia Chiorazzi, Valentina Carozzi, Guido Cavaletti, Marta Rui, Annamaria Marra, Daniela Rossi & Simona Collina. (2019) Anti-tumor Efficacy Assessment of the Sigma Receptor Pan Modulator RC-106. A Promising Therapeutic Tool for Pancreatic Cancer. Frontiers in Pharmacology 10.
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Ji Yea Kim, So Young Kim, Hong Seo Choi, Sungkwan An & Chun Jeih Ryu. (2019) Epitope mapping of anti-PGRMC1 antibodies reveals the non-conventional membrane topology of PGRMC1 on the cell surface. Scientific Reports 9:1.
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Carmen Abate, Mauro Niso & Francesco Berardi. (2018) Sigma-2 receptor: past, present and perspectives on multiple therapeutic exploitations. Future Medicinal Chemistry 10:16, pages 1997-2018.
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Anna Tesei, Michela Cortesi, Alice Zamagni, Chiara Arienti, Sara Pignatta, Michele Zanoni, Mayra Paolillo, Daniela Curti, Marta Rui, Daniela Rossi & Simona Collina. (2018) Sigma Receptors as Endoplasmic Reticulum Stress “Gatekeepers” and their Modulators as Emerging New Weapons in the Fight Against Cancer. Frontiers in Pharmacology 9.
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Laura Terzaghi, Alberto Maria Luciano, Priscila C Dall’Acqua, Silvia C Modina, John J Peluso & Valentina Lodde. (2018) PGRMC1 localization and putative function in the nucleolus of bovine granulosa cells and oocytes. Reproduction 155:3, pages 273-282.
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Ji Yea Kim, So Young Kim, Hong Seo Choi, Min Kyu Kim, Hyun Min Lee, Young-Joo Jang & Chun Jeih Ryu. (2018) Progesterone Receptor Membrane Component 1 suppresses the p53 and Wnt/β-catenin pathways to promote human pluripotent stem cell self-renewal. Scientific Reports 8:1.
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Yasuaki KabeHiroshi Handa & Makoto Suematsu. (2018) Function and structural regulation of the carbon monoxide (CO)-responsive membrane protein PGRMC1. Journal of Clinical Biochemistry and Nutrition 63:1, pages 12-17.
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Maria Laura Pati, Mauro Niso, Dirk Spitzer, Francesco Berardi, Marialessandra Contino, Chiara Riganti, William G. Hawkins & Carmen Abate. (2018) Multifunctional thiosemicarbazones and deconstructed analogues as a strategy to study the involvement of metal chelation, Sigma-2 (σ2) receptor and P-gp protein in the cytotoxic action: In vitro and in vivo activity in pancreatic tumors. European Journal of Medicinal Chemistry 144, pages 359-371.
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Maria Laura Pati, John R. Hornick, Mauro Niso, Francesco Berardi, Dirk Spitzer, Carmen Abate & William Hawkins. (2017) Sigma-2 receptor agonist derivatives of 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) induce cell death via mitochondrial superoxide production and caspase activation in pancreatic cancer. BMC Cancer 17:1.
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V. Russo, C. Inglese, L. Avallone, F. Roperto, C. Abate, N. Zizzo, J. S. Munday, F. Berardi, N. A. Colabufo & S. Roperto. (2017) Sigma 2 receptor expression levels in blood and bladder from healthy and bladder cancer cattle. Veterinary and Comparative Oncology 15:4, pages 1503-1512.
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Markos-Orestis Georgiadis, Olga Karoutzou, Angeliki-Sofia Foscolos & Ioannis Papanastasiou. (2017) Sigma Receptor (σR) Ligands with Antiproliferative and Anticancer Activity. Molecules 22:9, pages 1408.
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Chang S. Ryu, Kathrin Klein & Ulrich M. Zanger. (2017) Membrane Associated Progesterone Receptors: Promiscuous Proteins with Pleiotropic Functions – Focus on Interactions with Cytochromes P450. Frontiers in Pharmacology 8.
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Xiaofei Zhu, Mingde Ji, Yue Han, Yuanyuan Guo, Wenqiang Zhu, Feng Gao, Xuewen Yang & Chunbing Zhang. (2017) PGRMC1-dependent autophagy by hyperoside induces apoptosis and sensitizes ovarian cancer cells to cisplatin treatment. International Journal of Oncology 50:3, pages 835-846.
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Maria Laura Pati, Diana Groza, Chiara Riganti, Joanna Kopecka, Mauro Niso, Francesco Berardi, Sonja Hager, Petra Heffeter, Miwa Hirai, Hitoshi Tsugawa, Yasuaki Kabe, Makoto Suematsu & Carmen Abate. (2017) Sigma-2 receptor and progesterone receptor membrane component 1 (PGRMC1) are two different proteins: Proofs by fluorescent labeling and binding of sigma-2 receptor ligands to PGRMC1. Pharmacological Research 117, pages 67-74.
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Michael A. Cahill, Jalal A. Jazayeri, Susan M. Catalano, Shinya Toyokuni, Zaklina Kovacevic & Des R. Richardson. (2016) The emerging role of progesterone receptor membrane component 1 (PGRMC1) in cancer biology. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1866:2, pages 339-349.
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Marta Rui, Daniela Rossi, Annamaria Marra, Mayra Paolillo, Sergio Schinelli, Daniela Curti, Anna Tesei, Michela Cortesi, Alice Zamagni, Erik Laurini, Sabrina Pricl, Dirk Schepmann, Bernhard Wűnsch, Ernst Urban, Vittorio Pace & Simona Collina. (2016) Synthesis and biological evaluation of new aryl-alkyl(alkenyl)-4-benzylpiperidines, novel Sigma Receptor (SR) modulators, as potential anticancer-agents. European Journal of Medicinal Chemistry 124, pages 649-665.
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Robert B. PielIIIIII, Mesafint T. Shiferaw, Ajay A. Vashisht, Jason R. Marcero, Jeremy L. Praissman, John D. Phillips, James A. Wohlschlegel & Amy E. Medlock. (2016) A Novel Role for Progesterone Receptor Membrane Component 1 (PGRMC1): A Partner and Regulator of Ferrochelatase. Biochemistry 55:37, pages 5204-5217.
Crossref
Crossref
Mauro Niso, Maria Laura Pati, Francesco Berardi & Carmen Abate. (2016)
Rigid versus flexible anilines or anilides confirm the bicyclic ring as the hydrophobic portion for optimal σ
2
receptor binding and provide novel tools for the development of future σ
2
receptor PET radiotracers
. RSC Advances 6:91, pages 88508-88518.
Crossref
Crossref
Uyen B. Chu, Timur A. Mavlyutov, Ming-Liang Chu, Huan Yang, Amanda Schulman, Christophe Mesangeau, Christopher R. McCurdy, Lian-Wang Guo & Arnold E. Ruoho. (2015) The Sigma-2 Receptor and Progesterone Receptor Membrane Component 1 are Different Binding Sites Derived From Independent Genes. EBioMedicine 2:11, pages 1806-1813.
Crossref
Crossref
Aren van Waarde, Anna A. Rybczynska, Nisha K. Ramakrishnan, Kiichi Ishiwata, Philip H. Elsinga & Rudi A.J.O. Dierckx. (2015) Potential applications for sigma receptor ligands in cancer diagnosis and therapy. Biochimica et Biophysica Acta (BBA) - Biomembranes 1848:10, pages 2703-2714.
Crossref
Crossref
Carmen Abate, Mauro Niso, Vittoria Infantino, Alessio Menga & Francesco Berardi. (2015) Elements in support of the ‘non-identity’ of the PGRMC1 protein with the σ2 receptor. European Journal of Pharmacology 758, pages 16-23.
Crossref
Crossref
Mauro Niso, Chiara Riganti, Maria Laura Pati, Dario Ghigo, Francesco Berardi & Carmen Abate. (2015)
Novel and Selective Fluorescent σ
2
‐Receptor Ligand with a 3,4‐Dihydroisoquinolin‐1‐one Scaffold: A Tool to Study σ
2
Receptors in Living Cells
. ChemBioChem 16:7, pages 1078-1083.
Crossref
Crossref
Svetlana V. Selivanova, Annamaria Toscano, Carmen Abate, Francesco Berardi, Adrienne Müller, Stefanie D. Krämer, Roger Schibli & Simon M. Ametamey. (2015) Synthesis and pharmacological evaluation of 11C-labeled piperazine derivative as a PET probe for sigma-2 receptor imaging. Nuclear Medicine and Biology 42:4, pages 399-405.
Crossref
Crossref
Kaia K. Hampton, Rachel Stewart, Dana Napier, Pier Paolo Claudio & Rolf J. Craven. (2015) PGRMC1 Elevation in Multiple Cancers and Essential Role in Stem Cell Survival. Advances in Lung Cancer 04:03, pages 37-51.
Crossref
Crossref
Maria Laura Pati, Mauro Niso, Savina Ferorelli, Carmen Abate & Francesco Berardi. (2015)
Novel metal chelators thiosemicarbazones with activity at the σ
2
receptors and P-glycoprotein: an innovative strategy for resistant tumor treatment
. RSC Advances 5:125, pages 103131-103146.
Crossref
Crossref
Birgit Gellersen & Jan J. Brosens. (2014) Cyclic Decidualization of the Human Endometrium in Reproductive Health and Failure. Endocrine Reviews 35:6, pages 851-905.
Crossref
Crossref
Nicholas J. Izzo, Jinbin Xu, Chenbo Zeng, Molly J. Kirk, Kelsie Mozzoni, Colleen Silky, Courtney Rehak, Raymond Yurko, Gary Look, Gilbert Rishton, Hank Safferstein, Carlos Cruchaga, Alison Goate, Michael A. Cahill, Ottavio Arancio, Robert H. Mach, Rolf Craven, Elizabeth Head, Harry LeVine, Tara L. Spires-Jones & Susan M. Catalano. (2014) Alzheimer's Therapeutics Targeting Amyloid Beta 1–42 Oligomers II: Sigma-2/PGRMC1 Receptors Mediate Abeta 42 Oligomer Binding and Synaptotoxicity. PLoS ONE 9:11, pages e111899.
Crossref
Crossref
Noor O. Baqader, Marko Radulovic, Mark Crawford, Kai Stoeber & Jasminka Godovac-Zimmermann. (2014) Nuclear Cytoplasmic Trafficking of Proteins is a Major Response of Human Fibroblasts to Oxidative Stress. Journal of Proteome Research 13:10, pages 4398-4423.
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