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Review

Recombinant BCG as a vaccine vehicle to protect against tuberculosis

Pages 110-115 | Received 20 Sep 2009, Accepted 02 Nov 2009, Published online: 01 Mar 2010

Keep up to date with the latest research on this topic with citation updates for this article.

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Andreon Santos Machado da Silva, Lawrence Henrique Paz Albuquerque, Carlos Germano Garrido de Ponte, Matheus Rogério de Almeida, Sandra Elizabete Ribeiro de Faria, Mariana da Silva Ribeiro, Evelyn Nunes Goulart da Silva Pereira & Paulo Renato Zuquim Antas. (2022) Time to face the proofs: the BCG Moreau vaccine promotes superior inflammatory cytokine profile in vitro when compared with Russia, Pasteur, and Danish strains. Human Vaccines & Immunotherapeutics 18:1.
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Jin-Feng Zhong, Wei-Gao Wu, Xiao-Qing Zhang, Wei Tu, Zhen-Xiang Liu & Re-Jun Fang. (2016) Effects of dietary addition of heat-killed Mycobacterium phlei on growth performance, immune status and anti-oxidative capacity in early weaned piglets. Archives of Animal Nutrition 70:4, pages 249-262.
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Articles from other publishers (10)

Annuurun Nisa, Claudio Counoupas, Rachel Pinto, Warwick J. Britton & James A. Triccas. (2022) Characterization of the Protective Immune Responses Conferred by Recombinant BCG Overexpressing Components of Mycobacterium tuberculosis Sec Protein Export System. Vaccines 10:6, pages 945.
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Alok Kumar Singh, Monali Praharaj, Kara A. Lombardo, Takahiro Yoshida, Andres Matoso, Alex S. Baras, Liang Zhao, Geetha Srikrishna, Joy Huang, Pankaj Prasad, Jonathan D. Powell, Max Kates, David McConkey, Drew M. Pardoll, William R. Bishai & Trinity J. Bivalacqua. (2022) Re-engineered BCG overexpressing cyclic di-AMP augments trained immunity and exhibits improved efficacy against bladder cancer. Nature Communications 13:1.
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Sadiya Parveen, John R. Murphy & William R. Bishai. 2021. Advances in Host-Directed Therapies Against Tuberculosis. Advances in Host-Directed Therapies Against Tuberculosis 169 203 .
Peyman Habibi, Henry Daniell, Carlos Ricardo Soccol & Maria Fatima Grossi‐de‐Sa. (2019) The potential of plant systems to break the HIV‐TB link. Plant Biotechnology Journal 17:10, pages 1868-1891.
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Claudio Counoupas, Rachel Pinto, Gayathri Nagalingam, Warwick J. Britton & James A. Triccas. (2018) Protective efficacy of recombinant BCG over-expressing protective, stage-specific antigens of Mycobacterium tuberculosis. Vaccine 36:19, pages 2619-2629.
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James A. Triccas & Claudio Counoupas. (2016) Novel vaccination approaches to prevent tuberculosis in children. Pneumonia 8:1.
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Natalia V. Permyakova, Alla A. Zagorskaya, Pavel A. Belavin, Elena A. Uvarova, Olesya V. Nosareva, Andrey E. Nesterov, Anna A. Novikovskaya, Evgeniy L. Zav’yalov, Mikhail P. Moshkin & Elena V. Deineko. (2015) Transgenic Carrot Expressing Fusion Protein Comprising M. tuberculosis Antigens Induces Immune Response in Mice . BioMed Research International 2015, pages 1-11.
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Haniyeh Aghababa, Ashraf Mohabati Mobarez, Nima Khoramabadi, Mehrdad Behmanesh, Mehdi Mahdavi, Majid Tebianian & Mehdi Nejati. (2014) A Comparative Approach to Strategies for Cloning, Expression, and Purification of Mycobacterium tuberculosis Mycolyl Transferase 85B and Evaluation of Immune Responses in BALB/c Mice. Molecular Biotechnology 56:6, pages 487-497.
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Priya Saikumar Lakshmi, Dheeraj Verma, Xiangdong Yang, Bethany Lloyd & Henry Daniell. (2013) Low Cost Tuberculosis Vaccine Antigens in Capsules: Expression in Chloroplasts, Bio-Encapsulation, Stability and Functional Evaluation In Vitro. PLoS ONE 8:1, pages e54708.
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I.P. Nascimento & L.C.C. Leite. (2012) Recombinant vaccines and the development of new vaccine strategies. Brazilian Journal of Medical and Biological Research 45:12, pages 1102-1111.
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