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Mini Review

Structural biology of the PCI-protein fold

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Pages 118-123 | Received 04 Jun 2012, Accepted 12 Jun 2012, Published online: 01 Jul 2012

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A. A. Glukhova, M. M. Kurshakova, E. N. Nabirochkina, S. G. Georgieva & D. V. Kopytova. (2021) PCID2, a subunit of the Drosophila TREX-2 nuclear export complex, is essential for both mRNA nuclear export and its subsequent cytoplasmic trafficking. RNA Biology 18:11, pages 1969-1980.
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Susan Wagner, Anna Herrmannová, Radek Malík, Lucie Peclinovská & Leoš Shivaya Valášek. (2014) Functional and Biochemical Characterization of Human Eukaryotic Translation Initiation Factor 3 in Living Cells. Molecular and Cellular Biology 34:16, pages 3041-3052.
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Articles from other publishers (30)

Yulia A. Vdovina, Maria M. Kurshakova, Sofia G. Georgieva & Daria V. Kopytova. (2023) PCID2 Subunit of the Drosophila TREX-2 Complex Has Two RNA-Binding Regions. Current Issues in Molecular Biology 45:7, pages 5662-5676.
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Hu Yajie, Wang Shenglan, Zhao Wei, Li Rufang, Yang Tingting, Zhang Yunhui & Song Jie. (2023) Global quantitative proteomic analysis profiles of host protein expression in response to enterovirus A71 infection in bronchial epithelial cells based on tandem mass tag (TMT) peptide labeling coupled with LC-MS/MS uncovers the key role of proteasome in virus replication. Virus Research 330, pages 199118.
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Joshua J Peter, Helge M Magnussen, Paul A DaRosa, David Millrine, Stephen P Matthews, Frederic Lamoliatte, Ramasubramanian Sundaramoorthy, Ron R Kopito & Yogesh Kulathu. (2022) A non‐canonical scaffold‐type E3 ligase complex mediates protein UFMylation . The EMBO Journal 41:21.
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Sarah F. Ruidiaz, Jesper E. Dreier, Rasmus Hartmann‐Petersen & Birthe B. Kragelund. (2021) The disordered PCI ‐binding human proteins CSNAP and DSS1 have diverged in structure and function . Protein Science 30:10, pages 2069-2082.
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Hassan Hayek, Lauriane Gross, Aurélie Janvier, Laure Schaeffer, Franck Martin, Gilbert Eriani & Christine Allmang. (2021) eIF3 interacts with histone H4 messenger RNA to regulate its translation. Journal of Biological Chemistry 296, pages 100578.
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Rosa Woldegebriel, Jouni Kvist, Noora Andersson, Katrin Õunap, Karit Reinson, Monica H Wojcik, Emilia K Bijlsma, Mariëtte J V Hoffer, Monique M Ryan, Zornitza Stark, Maie Walsh, Inge Cuppen, Marie-Jose´ H van den Boogaard, Diana Bharucha-Goebel, Sandra Donkervoort, Sara Winchester, Roberto Zori, Carsten G Bönnemann, Reza Maroofian, Emer O’Connor, Henry Houlden, Fang Zhao, Olli Carpén, Matthew White, Jemeen Sreedharan, Murray Stewart, Emil Ylikallio & Henna Tyynismaa. (2020) Distinct effects on mRNA export factor GANP underlie neurological disease phenotypes and alter gene expression depending on intron content. Human Molecular Genetics 29:9, pages 1426-1439.
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Daniele Armaleo, Olaf Müller, François Lutzoni, Ólafur S. Andrésson, Guillaume Blanc, Helge B. Bode, Frank R. Collart, Francesco Dal Grande, Fred Dietrich, Igor V. Grigoriev, Suzanne Joneson, Alan Kuo, Peter E. Larsen, John M. LogsdonJrJr, David Lopez, Francis Martin, Susan P. May, Tami R. McDonald, Sabeeha S. Merchant, Vivian Miao, Emmanuelle Morin, Ryoko Oono, Matteo Pellegrini, Nimrod Rubinstein, Maria Virginia Sanchez-Puerta, Elizabeth Savelkoul, Imke Schmitt, Jason C. Slot, Darren Soanes, Péter Szövényi, Nicholas J. Talbot, Claire Veneault-Fourrey & Basil B. Xavier. (2019) The lichen symbiosis re-viewed through the genomes of Cladonia grayi and its algal partner Asterochloris glomerata. BMC Genomics 20:1.
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Karel Raabe, David Honys & Christos Michailidis. (2019) The role of eukaryotic initiation factor 3 in plant translation regulation. Plant Physiology and Biochemistry 145, pages 75-83.
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Murray Stewart. 2019. Macromolecular Protein Complexes II: Structure and Function. Macromolecular Protein Complexes II: Structure and Function 461 470 .
Ji-Ye Yin, Jian-Ting Zhang, Wei Zhang, Hong-Hao Zhou & Zhao-Qian Liu. (2018) eIF3a: A new anticancer drug target in the eIF family. Cancer Letters 412, pages 81-87.
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Leoš Shivaya Valášek, Jakub Zeman, Susan Wagner, Petra Beznosková, Zuzana Pavlíková, Mahabub Pasha Mohammad, Vladislava Hronová, Anna Herrmannová, Yaser Hashem & Stanislava Gunišová. (2017) Embraced by eIF3: structural and functional insights into the roles of eIF3 across the translation cycle. Nucleic Acids Research 45:19, pages 10948-10968.
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Lauren Budenholzer, Chin Leng Cheng, Yanjie Li & Mark Hochstrasser. (2017) Proteasome Structure and Assembly. Journal of Molecular Biology 429:22, pages 3500-3524.
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James M. B. Gordon, Shintaro Aibara & Murray Stewart. (2017) Structure of the Sac3 RNA-binding M-region in the Saccharomyces cerevisiae TREX-2 complex. Nucleic Acids Research 45:9, pages 5577-5585.
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Adetutu T. Egunsola, Yangjin Bae, Ming-Ming Jiang, David S. Liu, Yuqing Chen-Evenson, Terry Bertin, Shan Chen, James T. Lu, Lisette Nevarez, Nurit Magal, Annick Raas-Rothschild, Eric C. Swindell, Daniel H. Cohn, Richard A. Gibbs, Philippe M. Campeau, Mordechai Shohat & Brendan H. Lee. (2017) Loss of DDRGK1 modulates SOX9 ubiquitination in spondyloepimetaphyseal dysplasia. Journal of Clinical Investigation 127:4, pages 1475-1484.
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Prasanna Parasuraman, Peter Mulligan, James A. Walker, Bihua Li, Myriam Boukhali, Wilhelm Haas & Andre Bernards. (2017) Interaction of p190A RhoGAP with eIF3A and Other Translation Preinitiation Factors Suggests a Role in Protein Biosynthesis. Journal of Biological Chemistry 292:7, pages 2679-2689.
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Susan Wagner, Anna Herrmannová, Darina Šikrová & Leoš Shivaya Valášek. (2016) Human eIF3b and eIF3a serve as the nucleation core for the assembly of eIF3 into two interconnected modules: the yeast-like core and the octamer. Nucleic Acids Research 44:22, pages 10772-10788.
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Parimal Kumar, Christopher U.T. Hellen & Tatyana V. Pestova. (2016) Toward the mechanism of eIF4F-mediated ribosomal attachment to mammalian capped mRNAs. Genes & Development 30:13, pages 1573-1588.
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Birthe B. Kragelund, Signe M. Schenstrøm, Caio A. Rebula, Vikram Govind Panse & Rasmus Hartmann-Petersen. (2016) DSS1/Sem1, a Multifunctional and Intrinsically Disordered Protein. Trends in Biochemical Sciences 41:5, pages 446-459.
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Cindy Meister, Miriam Kolog Gulko, Anna M. Köhler & Gerhard H. Braus. (2015) The devil is in the details: comparison between COP9 signalosome (CSN) and the LID of the 26S proteasome. Current Genetics 62:1, pages 129-136.
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Amedee des Georges, Vidya Dhote, Lauriane Kuhn, Christopher U. T. Hellen, Tatyana V. Pestova, Joachim Frank & Yaser Hashem. (2015) Structure of mammalian eIF3 in the context of the 43S preinitiation complex. Nature 525:7570, pages 491-495.
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Lyudmila Dimitrova, Eugene Valkov, Shintaro Aibara, Dirk Flemming, Stephen H. McLaughlin, Ed Hurt & Murray Stewart. (2015) Structural Characterization of the Chaetomium thermophilum TREX-2 Complex and its Interaction with the mRNA Nuclear Export Factor Mex67:Mtr2. Structure 23:7, pages 1246-1257.
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Qianjun Liu, Guodong Hu, Zanxia Cao, Jihua Wang & Haifeng Chen. (2015) Conformational stability of PCID2 upon DSS1 binding with molecular dynamics simulation. Journal of Molecular Modeling 21:5.
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Ruth Singer, Shimshi Atar, Osnat Atias, Efrat Oron, Daniel Segal, Joel A. Hirsch, Tamir Tuller, Amir Orian & Daniel A. Chamovitz. (2014) Drosophila COP9 signalosome subunit 7 interacts with multiple genomic loci to regulate development. Nucleic Acids Research 42:15, pages 9761-9770.
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Gondichatnahalli M. Lingaraju, Richard D. Bunker, Simone Cavadini, Daniel Hess, Ulrich Hassiepen, Martin Renatus, Eric S. Fischer & Nicolas H. Thomä. (2014) Crystal structure of the human COP9 signalosome. Nature 512:7513, pages 161-165.
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Jan P. Erzberger, Florian Stengel, Riccardo Pellarin, Suyang Zhang, Tanja Schaefer, Christopher H.S. Aylett, Peter Cimermančič, Daniel Boehringer, Andrej Sali, Ruedi Aebersold & Nenad Ban. (2014) Molecular Architecture of the 40S⋅eIF1⋅eIF3 Translation Initiation Complex. Cell 158:5, pages 1123-1135.
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Sohail Khoshnevis, Stanislava Gunišová, Vladislava Vlčková, Tomáš Kouba, Piotr Neumann, Petra Beznosková, Ralf Ficner & Leoš Shivaya Valášek. (2022) Structural integrity of the PCI domain of eIF3a/TIF32 is required for mRNA recruitment to the 43S pre-initiation complexes. Nucleic Acids Research 42:6, pages 4123-4139.
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Corey N. Cunningham, Casey A. Schmidt, Nathaniel J. Schramm, Michelle R. Gaylord & Karen K. Resendes. (2014) Human TREX2 components PCID2 and centrin 2, but not ENY2, have distinct functions in protein export and co-localize to the centrosome. Experimental Cell Research 320:2, pages 209-218.
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Stephan Wagner, Johannes Stuttmann, Steffen Rietz, Raphael Guerois, Elena Brunstein, Jaqueline Bautor, Karsten Niefind & Jane E. Parker. (2013) Structural Basis for Signaling by Exclusive EDS1 Heteromeric Complexes with SAG101 or PAD4 in Plant Innate Immunity. Cell Host & Microbe 14:6, pages 619-630.
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Encar García-Oliver, Pau Pascual-García, Varinia García-Molinero, Tineke L. Lenstra, Frank C. P. Holstege & Susana Rodríguez-Navarro. (2013) A novel role for Sem1 and TREX-2 in transcription involves their impact on recruitment and H2B deubiquitylation activity of SAGA. Nucleic Acids Research 41:11, pages 5655-5668.
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Giovanna Serino & Elah Pick. (2013) Duplication and familial promiscuity within the proteasome lid and COP9 signalosome kin complexes. Plant Science 203-204, pages 89-97.
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