836
Views
39
CrossRef citations to date
0
Altmetric
Research Paper

TGFβ-dependent induction of interleukin-11 and interleukin-8 involves SMAD and p38 MAPK pathways in breast tumor models with varied bone metastases potential

, , &
Pages 311-316 | Received 11 Jul 2010, Accepted 03 Nov 2010, Published online: 01 Feb 2011

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Nagat Frara, Paul W. Fisher, Yingjie Zhao, Joseph T. Tarr, Mamta Amin, Steven N. Popoff & Mary F. Barbe. (2018) Substance P increases CCN2 dependent on TGF-beta yet Collagen Type I via TGF-beta1 dependent and independent pathways in tenocytes. Connective Tissue Research 59:1, pages 30-44.
Read now
Donatella Vizza, Anna Perri, Giuseppina Toteda, Simona Lupinacci, Francesca Leone, Paolo Gigliotti, Danilo Lofaro, Antonella La Russa & Renzo Bonofiglio. (2015) Nerve growth factor exposure promotes tubular epithelial–mesenchymal transition via TGF-β1 signaling activation. Growth Factors 33:3, pages 169-180.
Read now

Articles from other publishers (37)

Kanako Sasaki, Shotaro Komamura & Kazuyuki Matsuda. (2023) Extracellular stimulation of lung fibroblasts with arachidonic acid increases interleukin 11 expression through p38 and ERK signaling. Biological Chemistry 404:1, pages 59-69.
Crossref
Bingzi Dong, Jingjing Zhu, Xian Chen, Hongyuan Jiang, Yujie Deng, Lili Xu, Yangang Wang & Shufa Li. (2023) The Emerging Role of Interleukin-(IL)-11/IL-11R in Bone Metabolism and Homeostasis: From Cytokine to Osteokine. Aging and disease 14:6, pages 2113.
Crossref
Jiaojiao Xu, Luyao Ma, Danqing Wang & Jianhong Yang. (2022) Uncarboxylated osteocalcin promotes proliferation and metastasis of MDA-MB-231 cells through TGF-β/SMAD3 signaling pathway. BMC Molecular and Cell Biology 23:1.
Crossref
Marie-Therese Haider, Daniel J. Smit & Hanna Taipaleenmäki. (2022) MicroRNAs: Emerging Regulators of Metastatic Bone Disease in Breast Cancer. Cancers 14:3, pages 729.
Crossref
Andrew G. Kunihiro, Julia A. Brickey, Jennifer B. Frye, Julia N. Cheng, Paula B. Luis, Claus Schneider & Janet L. Funk. (2022) Curcumin Inhibition of TGFβ signaling in bone metastatic breast cancer cells and the possible role of oxidative metabolites. The Journal of Nutritional Biochemistry 99, pages 108842.
Crossref
Paola Maroni, Paola Bendinelli, Anita Ferraretto & Giovanni Lombardi. (2021) Interleukin 11 (IL-11): Role(s) in Breast Cancer Bone Metastases. Biomedicines 9:6, pages 659.
Crossref
Dylan Dieters-Castator, Paola M. Dantonio, Matt Piaseczny, Guihua Zhang, Jiahui Liu, Miljan Kuljanin, Stephen Sherman, Michael Jewer, Katherine Quesnel, Eun Young Kang, Martin Köbel, Gabrielle M. Siegers, Andrew Leask, David Hess, Gilles Lajoie & Lynne-Marie Postovit. (2021) Embryonic protein NODAL regulates the breast tumor microenvironment by reprogramming cancer-derived secretomes. Neoplasia 23:4, pages 375-390.
Crossref
Ji‐Ming Bao, Qiang Dang, Chun‐Jung Lin, U‐Ging Lo, Boris Feldkoren, Andrew Dang, Elizabeth Hernandez, Fei Li, Vandana Panwar, Cheng‐Fan Lee, Jun‐Jie Cen, Bing Guan, Vitaly Margulis, Payal Kapur, Rolf A. Brekken, Jun‐Hang Luo, Jer‐Tsong Hsieh & Wan‐Long Tan. (2020) SPARC is a key mediator of TGF‐β‐induced renal cancer metastasis. Journal of Cellular Physiology 236:3, pages 1926-1938.
Crossref
Yucheng Wang, Shihong Ren, Zhan Wang, Zenan Wang, Ning Zhu, Danyang Cai, Zhaoming Ye & Jianwei Ruan. (2020) Chemokines in bone-metastatic breast cancer: Therapeutic opportunities. International Immunopharmacology 87, pages 106815.
Crossref
Weidong Xu, Yuefeng Yang, Zebin Hu, Maria Head, Kathy A. Mangold, Megan Sullivan, Edward Wang, Poornima Saha, Kamalakar Gulukota, Donald L. Helseth, Theresa Guise, Bellur S. Prabhkar, Karen Kaul, Hans SchreiberPrem Seth. (2020) LyP-1-Modified Oncolytic Adenoviruses Targeting Transforming Growth Factor β Inhibit Tumor Growth and Metastases and Augment Immune Checkpoint Inhibitor Therapy in Breast Cancer Mouse Models. Human Gene Therapy 31:15-16, pages 863-880.
Crossref
Pierrick G.J. Fournier, Liria M. Fajardo-Yamamoto & Patricia Juárez. 2020. Encyclopedia of Bone Biology. Encyclopedia of Bone Biology 281 293 .
Francesca Salamanna, Veronica Borsari, Deyanira Contartese, Viviana Costa, Gianluca Giavaresi & Milena Fini. (2019) What Is the Role of Interleukins in Breast Cancer Bone Metastases? A Systematic Review of Preclinical and Clinical Evidence. Cancers 11:12, pages 2018.
Crossref
Sheng-Jun Liao, Jing Luo, Dong Li, Yuan-Hong Zhou, Bin Yan, Jing-Jing Wei, Jian-Cheng Tu, Yi-Rong Li, Gui-Mei Zhang & Zuo-Hua Feng. (2019) TGF-β1 and TNF-α synergistically induce epithelial to mesenchymal transition of breast cancer cells by enhancing TAK1 activation. Journal of Cell Communication and Signaling 13:3, pages 369-380.
Crossref
Carmel Mothersill, Andrej Rusin & Colin Seymour. (2019) Relevance of Non-Targeted Effects for Radiotherapy and Diagnostic Radiology; A Historical and Conceptual Analysis of Key Players. Cancers 11:9, pages 1236.
Crossref
Ju-Suk NamAshish Ranjan SharmaLich Thi NguyenSupriya JaggaYeon-Hee LeeGarima SharmaSang-Soo Lee. (2018) Lysophosphatidic acid enhances breast cancer cells-mediated osteoclastogenesis. The Korean Journal of Physiology & Pharmacology 22:5, pages 503.
Crossref
Manica Negahdaripour, Navid Nezafat & Younes Ghasemi. (2016) A panoramic review and in silico analysis of IL-11 structure and function. Cytokine & Growth Factor Reviews 32, pages 41-61.
Crossref
Zhaoming Zhong, Zedong Hu, Yue Jiang, Ruimei Sun, Xue Chen, Hongying Chu, Musheng Zeng & Chuanzheng Sun. (2016) Interleukin-11 promotes epithelial-mesenchymal transition in anaplastic thyroid carcinoma cells through PI3K/Akt/GSK3β signaling pathway activation. Oncotarget 7:37, pages 59652-59663.
Crossref
Amy Winship, Ellen Menkhorst, Michelle Van Sinderen & Evdokia Dimitriadis. (2016) Interleukin 11: similar or opposite roles in female reproduction and reproductive cancer?. Reproduction, Fertility and Development 28:4, pages 395.
Crossref
Yuefeng Yang, Weidong Xu, Thomas Neill, Zebin Hu, Chi-Hsiung Wang, Xianghui Xiao, Stuart R. Stock, Theresa Guise, Chae-Ok YunCharles B. Brendler, Renato V. Iozzo & Prem Seth. (2015) Systemic Delivery of an Oncolytic Adenovirus Expressing Decorin for the Treatment of Breast Cancer Bone Metastases. Human Gene Therapy 26:12, pages 813-825.
Crossref
Lin Yu, Xin Liu, Kang Cui, Yanbo Di, Lingbiao Xin, Xiaoming Sun, Wei Zhang, Xi Yang, Minxin Wei, Zhi Yao & Jie Yang. (2015) SND1 Acts Downstream of TGFβ1 and Upstream of Smurf1 to Promote Breast Cancer Metastasis. Cancer Research 75:7, pages 1275-1286.
Crossref
Alexandra Stähli, Dieter Bosshardt, Anton Sculean & Reinhard Gruber. (2014) Emdogain-Regulated Gene Expression in Palatal Fibroblasts Requires TGF-βRI Kinase Signaling. PLoS ONE 9:9, pages e105672.
Crossref
Hassan Fazilaty & Parvin Mehdipour. (2014) Genetics of breast cancer bone metastasis: a sequential multistep pattern. Clinical & Experimental Metastasis 31:5, pages 595-612.
Crossref
Tilman D. Rachner & Lorenz C. Hofbauer. 2014. Knochenmetastasen. Knochenmetastasen 13 21 .
David Krimmer, Yukikazu Ichimaru, Janette Burgess, Judith Black & Brian Oliver. (2013) Exposure to Biomass Smoke Extract Enhances Fibronectin Release from Fibroblasts. PLoS ONE 8:12, pages e83938.
Crossref
Erin M McCoy, Huixian Hong, Hawley C Pruitt & Xu Feng. (2013) IL-11 produced by breast cancer cells augments osteoclastogenesis by sustaining the pool of osteoclast progenitor cells. BMC Cancer 13:1.
Crossref
Li Ren, Xia Wang, Zuoliang Dong, Jun Liu & Shiwu Zhang. (2013) Bone metastasis from breast cancer involves elevated IL-11 expression and the gp130/STAT3 pathway. Medical Oncology 30:3.
Crossref
Nicola Ferrari, Laura McDonald, Joanna S. Morris, Ewan R. Cameron & Karen Blyth. (2013) RUNX2 in mammary gland development and breast cancer. Journal of Cellular Physiology 228:6, pages 1137-1142.
Crossref
Barbara Onnis, Nicole Fer, Annamaria Rapisarda, Victor S. Perez & Giovanni Melillo. (2013) Autocrine production of IL-11 mediates tumorigenicity in hypoxic cancer cells. Journal of Clinical Investigation 123:4, pages 1615-1629.
Crossref
Neil E. Bhola, Justin M. Balko, Teresa C. Dugger, María Gabriela Kuba, Violeta Sánchez, Melinda Sanders, Jamie Stanford, Rebecca S. Cook & Carlos L. Arteaga. (2013) TGF-β inhibition enhances chemotherapy action against triple-negative breast cancer. Journal of Clinical Investigation 123:3, pages 1348-1358.
Crossref
Liang-Chih Liu, Thomas Chang-Yao Tsao, Shu-Rong Hsu, Hwei-Chung Wang, Tsuen-Chiuan Tsai, Jung-Yie Kao & Tzong-Der Way. (2012) EGCG Inhibits Transforming Growth Factor-β-Mediated Epithelial-to-Mesenchymal Transition via the Inhibition of Smad2 and Erk1/2 Signaling Pathways in Nonsmall Cell Lung Cancer Cells. Journal of Agricultural and Food Chemistry 60:39, pages 9863-9873.
Crossref
Z Zhang, Z Hu, J Gupta, J D Krimmel, H M Gerseny, A F Berg, J S Robbins, H Du, B Prabhakar & P Seth. (2012) Intravenous administration of adenoviruses targeting transforming growth factor beta signaling inhibits established bone metastases in 4T1 mouse mammary tumor model in an immunocompetent syngeneic host. Cancer Gene Therapy 19:9, pages 630-636.
Crossref
Zebin HuJanhavi GuptaZhenwei ZhangHelen GersenyArthur BergYun Ju ChenZhiling ZhangHongyan DuCharles B. BrendlerXianghui XiaoKenneth J. PientaTheresa GuiseChung LeePaula H. SternStuart StockPrem Seth. (2012) Systemic Delivery of Oncolytic Adenoviruses Targeting Transforming Growth Factor-β Inhibits Established Bone Metastasis in a Prostate Cancer Mouse Model. Human Gene Therapy 23:8, pages 871-882.
Crossref
Cinzia Raso, Carlo Cosentino, Marco Gaspari, Natalia Malara, Xuemei Han, Daniel McClatchy, Sung Kyu Park, Maria Renne, Nuria Vadalà, Ubaldo Prati, Giovanni Cuda, Vincenzo Mollace, Francesco Amato & John R. YatesIIIIII. (2012) Characterization of Breast Cancer Interstitial Fluids by TmT Labeling, LTQ-Orbitrap Velos Mass Spectrometry, and Pathway Analysis. Journal of Proteome Research 11:6, pages 3199-3210.
Crossref
Sirkku Pollari, Rami S. Käkönen, Khalid S. Mohammad, Jukka P. Rissanen, Jussi M. Halleen, Anni Wärri, Liisa Nissinen, Marjo Pihlavisto, Anne Marjamäki, Merja Perälä, Theresa A. Guise, Olli Kallioniemi & Sanna-Maria Käkönen. (2012) Heparin-like Polysaccharides Reduce Osteolytic Bone Destruction and Tumor Growth in a Mouse Model of Breast Cancer Bone Metastasis. Molecular Cancer Research 10:5, pages 597-604.
Crossref
Gary D. Slade, Mathew S. Conrad, Luda Diatchenko, Naim U. Rashid, Sheng Zhong, Shad Smith, Jesse Rhodes, Alex Medvedev, Sergei Makarov, William Maixner & Andrea G. Nackley. (2011) Cytokine biomarkers and chronic pain: Association of genes, transcription, and circulating proteins with temporomandibular disorders and widespread palpation tenderness. Pain 152:12, pages 2802-2812.
Crossref
Michelle M. Schiro, Sara E. Stauber, Tami L. Peterson, Chateen Krueger, Steven J. Darnell, Kenneth A. Satyshur, Norman R. Drinkwater, Michael A. Newton & F. Michael Hoffmann. (2011) Mutations in Protein-Binding Hot-Spots on the Hub Protein Smad3 Differentially Affect Its Protein Interactions and Smad3-Regulated Gene Expression. PLoS ONE 6:9, pages e25021.
Crossref
Zebin Hu, Helen Gerseny, Zhenwei Zhang, Yun-Ju Chen, Arthur Berg, Zhiling Zhang, Stuart Stock & Prem Seth. (2011) Oncolytic Adenovirus Expressing Soluble TGFβ Receptor II-Fc-mediated Inhibition of Established Bone Metastases: A Safe and Effective Systemic Therapeutic Approach for Breast Cancer. Molecular Therapy 19:9, pages 1609-1618.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.