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Research Paper

Pharmacologic synergy between dual phosphoinositide-3-kinase and mammalian target of rapamycin inhibition and 5-Fluorouracil in PIK3CA mutant gastric cancer cells

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Pages 34-42 | Received 07 Jul 2011, Accepted 16 Oct 2011, Published online: 01 Jan 2012

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Hong Zou, Li Li, Ines Garcia Carcedo, Zhi Ping Xu, Michael Monteiro & Wenyi Gu. (2016) Synergistic inhibition of colon cancer cell growth with nanoemulsion-loaded paclitaxel and PI3K/mTOR dual inhibitor BEZ235 through apoptosis. International Journal of Nanomedicine 11, pages 1947-1958.
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Jiezhong Chen, Renfu Shao, Li Li, Zhi Ping Xu & Wenyi Gu. (2014) Effective inhibition of colon cancer cell growth with MgAl-layered double hydroxide (LDH) loaded 5-FU and PI3K/mTOR dual inhibitor BEZ-235 through apoptotic pathways. International Journal of Nanomedicine 9, pages 3403-3411.
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Mikhail V. Blagosklonny. (2012) Rapalogs in cancer prevention. Cancer Biology & Therapy 13:14, pages 1349-1354.
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Shikha Satendra Singh. (2015) Targeting the PI3K/Akt signaling pathway in gastric carcinoma: A reality for personalized medicine?. World Journal of Gastroenterology 21:43, pages 12261.
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Wei Yang, Alexander Raufi & Samuel J. Klempner. (2014) Targeted therapy for gastric cancer: Molecular pathways and ongoing investigations. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1846:1, pages 232-237.
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B Bhattacharya, S H H Low, C Soh, N Kamal Mustapa, M Beloueche-Babari, K X Koh, J Loh & R Soong. (2014) Increased drug resistance is associated with reduced glucose levels and an enhanced glycolysis phenotype. British Journal of Pharmacology 171:13, pages 3255-3267.
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