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Sundarapandian Thangapandian, Shalini John & Keun
Woo Lee. (2012) Molecular Dynamics Simulation Study Explaining Inhibitor Selectivity in Different Class of Histone Deacetylases. Journal of Biomolecular Structure and Dynamics 29:4, pages 677-698.
Read now
Read now
Qiu Zhang, Wei Feng, Hongyu Zhou & Bing Yan. (2009) Advances in preclinical small molecules for the treatment of NSCLC. Expert Opinion on Therapeutic Patents 19:6, pages 731-751.
Read now
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Roberto R Rosato & Steven Grant. (2005) Histone deacetylase inhibitors: insights into mechanisms of lethality. Expert Opinion on Therapeutic Targets 9:4, pages 809-824.
Read now
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Thea Kalebic. (2003) Epigenetic transitions: towards therapeutic targets. Expert Opinion on Therapeutic Targets 7:6, pages 693-699.
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Articles from other publishers (110)
Dehua Lu, Lailiang Qu, Cheng Wang, Heng Luo, Shang Li, Fucheng Yin, Xingchen Liu, Xinye Chen, Zhongwen Luo, Ningjie Cui, Wan Peng, Limei Ji, Lingyi Kong & Xiaobing Wang. (2022) Harmine-based dual inhibitors targeting histone deacetylase (HDAC) and DNA as a promising strategy for cancer therapy. Bioorganic Chemistry 120, pages 105604.
Crossref
Crossref
Marta Halasa, Kamila Adamczuk, Grzegorz Adamczuk, Syeda Afshan, Andrzej Stepulak, Marek Cybulski & Anna Wawruszak. (2021) Deacetylation of Transcription Factors in Carcinogenesis. International Journal of Molecular Sciences 22:21, pages 11810.
Crossref
Crossref
Han-Gyu Chang, Yong-Hyeon Choi, JinWoo Hong, Joung-Woo Choi, A-Rum Yoon & Chae-Ok Yun. (2021) GM101 in Combination with Histone Deacetylase Inhibitor Enhances Anti-Tumor Effects in Desmoplastic Microenvironment. Cells 10:11, pages 2811.
Crossref
Crossref
Yuka Ikeda, Nozomi Nagase, Ai Tsuji, Kurumi Taniguchi, Yasuko Kitagishi & Satoru Matsuda. (2021) Comprehension of the Relationship between Autophagy and Reactive Oxygen Species for Superior Cancer Therapy with Histone Deacetylase Inhibitors. Oxygen 1:1, pages 22-31.
Crossref
Crossref
Johannes Karges, Thirumal Yempala, Mickaël Tharaud, Dan Gibson & Gilles Gasser. (2020)
A Multi‐action and Multi‐target Ru
II
–Pt
IV
Conjugate Combining Cancer‐Activated Chemotherapy and Photodynamic Therapy to Overcome Drug Resistant Cancers
. Angewandte Chemie International Edition 59:18, pages 7069-7075.
Crossref
Crossref
Johannes Karges, Thirumal Yempala, Mickaël Tharaud, Dan Gibson & Gilles Gasser. (2020)
A Multi‐action and Multi‐target Ru
II
–Pt
IV
Conjugate Combining Cancer‐Activated Chemotherapy and Photodynamic Therapy to Overcome Drug Resistant Cancers
. Angewandte Chemie 132:18, pages 7135-7141.
Crossref
Crossref
Wen-juan Liu, Yue Du, Ru Wen, Ming Yang & Jian Xu. (2020) Drug resistance to targeted therapeutic strategies in non-small cell lung cancer. Pharmacology & Therapeutics 206, pages 107438.
Crossref
Crossref
Maria Cosenza & Samantha Pozzi. (2018) The Therapeutic Strategy of HDAC6 Inhibitors in Lymphoproliferative Disease. International Journal of Molecular Sciences 19:8, pages 2337.
Crossref
Crossref
Mengya ZhaoLin LiJundong ZhouXueyuan CuiQingmei TianYaqing JinYimin Zhu. (2018) MiR-2861 Behaves as a Biomarker of Lung Cancer Stem Cells and Regulates the HDAC5-ERK System Genes. Cellular Reprogramming 20:2, pages 99-106.
Crossref
Crossref
Ye Wei, Fangzheng Zhou, Zhenyu Lin, Liangliang Shi, Ai Huang, Tao Liu, Dandan Yu & Gang Wu. (2018) Antitumor effects of histone deacetylase inhibitor suberoylanilide hydroxamic acid in epidermal growth factor receptor-mutant non-small-cell lung cancer lines in vitro and in vivo. Anti-Cancer Drugs 29:3, pages 262-270.
Crossref
Crossref
Michal Schaap-FoglerIrit BaharAda RephaeliMor DahbashAbraham NudelmanEitan LivnyTilda BarliyaYael NisgavTami Livnat. (2017) Effect of Histone Deacetylase Inhibitor, Butyroyloxymethyl-Diethyl Phosphate (AN-7), on Corneal Neovascularization in a Mouse Model. Journal of Ocular Pharmacology and Therapeutics 33:6, pages 480-486.
Crossref
Crossref
Reema Zeineldin & Joan Syoufjy. 2017. Cancer Nanotechnology. Cancer Nanotechnology
3
12
.
Mohamed I. Khalil, Bardees M. Foda, Susmitha Suresh & Upinder Singh. (2016) Technical advances in trigger-induced RNA interference gene silencing in the parasite Entamoeba histolytica. International Journal for Parasitology 46:3, pages 205-212.
Crossref
Crossref
Wu Yuanfeng, Xiao Gongnian, Mao Jianwei, Liu Shiwang, Huang Jun & Mei Lehe. (2015) Dietary sulforaphane inhibits histone deacetylase activity in B16 melanoma cells. Journal of Functional Foods 18, pages 182-189.
Crossref
Crossref
Dörthe Schaue & William H. McBride. (2015) Opportunities and challenges of radiotherapy for treating cancer. Nature Reviews Clinical Oncology 12:9, pages 527-540.
Crossref
Crossref
Fan-Suo Zeng, Feng-Kun Sun, Nan-Song Liang, Xing-Tang Zhao, Wei Luo & Ya-Guang Zhan. (2015) Dynamic change of DNA methylation and cell redox state at different micropropagation phases in birch. Trees 29:3, pages 917-930.
Crossref
Crossref
Vivek Vaish, Tripti Khare, Mukesh Verma & Sharad Khare. 2015. Cancer Epigenetics. Cancer Epigenetics
771
782
.
Victoria L. Luchenko, Thomas Litman, Arup R. Chakraborty, Aaron Heffner, Christopher Devor, Julia Wilkerson, Wilfred Stein, Robert W. Robey, Lois Bangiolo, David Levens & Susan E. Bates. (2014) Histone deacetylase inhibitor‐mediated cell death is distinct from its global effect on chromatin. Molecular Oncology 8:8, pages 1379-1392.
Crossref
Crossref
You Zhou, De-Si Pan, Song Shan, Jing-Zhong Zhu, Kun Zhang, Xu-Peng Yue, Li-Ping Nie, Jun Wan, Xian-Ping Lu, Wei Zhang & Zhi-Qiang Ning. (2014) Non-toxic dose chidamide synergistically enhances platinum-induced DNA damage responses and apoptosis in Non-Small-Cell lung cancer cells. Biomedicine & Pharmacotherapy 68:4, pages 483-491.
Crossref
Crossref
Rui‐Rong Ye, Zhuo‐Feng Ke, Cai‐Ping Tan, Liang He, Liang‐Nian Ji & Zong‐Wan Mao. (2013) Histone‐Deacetylase‐Targeted Fluorescent Ruthenium(II) Polypyridyl Complexes as Potent Anticancer Agents. Chemistry – A European Journal 19:31, pages 10160-10169.
Crossref
Crossref
Mi Hwa Park, You-Jin Jeon, Hak-Ju Kim & Ji Sook Han. (2013)
Effect of Diphlorethohydroxycarmalol Isolated From
Ishige okamurae
on Apoptosis in 3 t3-L1 Preadipocytes
. Phytotherapy Research 27:6, pages 931-936.
Crossref
Crossref
Patricia García-Domínguez, Carmela Dell’Aversana, Rosana Alvarez, Lucia Altucci & Ángel R. de Lera. (2013) Synthetic approaches to DNMT inhibitor SGI-1027 and effects on the U937 leukemia cell line. Bioorganic & Medicinal Chemistry Letters 23:6, pages 1631-1635.
Crossref
Crossref
Himashinie V.K. Diyabalanage, Michael L. Granda & Jacob M. Hooker. (2013) Combination therapy: Histone deacetylase inhibitors and platinum-based chemotherapeutics for cancer. Cancer Letters 329:1, pages 1-8.
Crossref
Crossref
Takuya Azechi, Dan Kanehira, Takashi Kobayashi, Ryo Sudo, Akiko Nishimura, Fumiaki Sato & Hiroshi Wachi. (2013) Trichostatin A, an HDAC Class I/II Inhibitor, Promotes Pi-Induced Vascular Calcification Via Up-Regulation of the Expression of Alkaline Phosphatase. Journal of Atherosclerosis and Thrombosis 20:6, pages 538-547.
Crossref
Crossref
Patricia García-Domínguez, Mélanie Weiss, Ilaria Lepore, Rosana Álvarez, Lucia Altucci, Hinrich Gronemeyer & Ángel R. de Lera. (2012) A DNA Methyltransferase Modulator Inspired by Peyssonenyne Natural Product Structures. ChemMedChem 7:12, pages 2101-2112.
Crossref
Crossref
Kimberley Kallsen, Ellen Andresen & Holger Heine. (2012) Histone Deacetylase (HDAC) 1 Controls the Expression of Beta Defensin 1 in Human Lung Epithelial Cells. PLoS ONE 7:11, pages e50000.
Crossref
Crossref
Ke Gong, Chao Chen, Yao Zhan, Yan Chen, Zebo Huang & Wenhua Li. (2012) Autophagy-related Gene 7 (ATG7) and Reactive Oxygen Species/Extracellular Signal-regulated Kinase Regulate Tetrandrine-induced Autophagy in Human Hepatocellular Carcinoma. Journal of Biological Chemistry 287:42, pages 35576-35588.
Crossref
Crossref
Zi-jian Shi, Dong-yun Ouyang, Jun-shan Zhu, Li-hui Xu & Xian-hui He. (2012) Histone deacetylase inhibitor suberoylanilide hydroxamic acid exhibits anti-inflammatory activities through induction of mitochondrial damage and apoptosis in activated lymphocytes. International Immunopharmacology 12:4, pages 580-587.
Crossref
Crossref
Nataly Tarasenko, Gania Kessler-Icekson, Pnina Boer, Aida Inbal, Hadassa Schlesinger, Don R. Phillips, Suzanne M. Cutts, Abraham Nudelman & Ada Rephaeli. (2010) The histone deacetylase inhibitor butyroyloxymethyl diethylphosphate (AN-7) protects normal cells against toxicity of anticancer agents while augmenting their anticancer activity. Investigational New Drugs 30:1, pages 130-143.
Crossref
Crossref
Wei-Jian Sun, Xiang Zhou, Ji-Hang Zheng, Ming-Dong Lu, Jian-Yun Nie, Xiang-Jiao Yang & Zhi-Qiang Zheng. (2012) Histone acetyltransferases and deacetylases: molecular and clinical implications to gastrointestinal carcinogenesis. Acta Biochimica et Biophysica Sinica 44:1, pages 80-91.
Crossref
Crossref
Wayne Bidlack & Raymond RodriguezSharon Ross. 2011. Nutritional Genomics. Nutritional Genomics
3
24
.
Hwang Gyun Jeon, Cheol Yong Yoon, Ji Hyeong Yu, Mi Jeong Park, Jung Eun Lee, Seong Jin Jeong, Sung Kyu Hong, Seok-Soo Byun & Sang Eun Lee. (2011) Induction of Caspase Mediated Apoptosis and Down-Regulation of Nuclear Factor-κB and Akt Signaling are Involved in the Synergistic Antitumor Effect of Gemcitabine and the Histone Deacetylase Inhibitor Trichostatin A in Human Bladder Cancer Cells. Journal of Urology 186:5, pages 2084-2093.
Crossref
Crossref
Markus Weiller, Timo Weiland, Georg Dünstl, Ulrike Sack, Gerald Künstle & Albrecht Wendel. (2011) Differential immunotoxicity of histone deacetylase inhibitors on malignant and naïve hepatocytes. Experimental and Toxicologic Pathology 63:5, pages 511-517.
Crossref
Crossref
M. M. Lino & A. Merlo. (2010) PI3Kinase signaling in glioblastoma. Journal of Neuro-Oncology 103:3, pages 417-427.
Crossref
Crossref
Eun-Ra Jang, Yun Jeong Kim, Soon Chul Myung, Wonyong Kim & Chung Soo Lee. (2011) Different effect of protein kinase B/Akt and extracellular signal-regulated kinase inhibition on trichostatin A-induced apoptosis in epithelial ovarian carcinoma cell lines. Molecular and Cellular Biochemistry 353:1-2, pages 1-11.
Crossref
Crossref
José García, Gianluigi Franci, Raquel Pereira, Rosaria Benedetti, Angela Nebbioso, Fátima Rodríguez-Barrios, Hinrich Gronemeyer, Lucia Altucci & Angel R. de Lera. (2011) Epigenetic profiling of the antitumor natural product psammaplin A and its analogues. Bioorganic & Medicinal Chemistry 19:12, pages 3637-3649.
Crossref
Crossref
Eun Jin Lim, Thomas X. Lu, Carine Blanchard & Marc E. Rothenberg. (2011) Epigenetic Regulation of the IL-13-induced Human Eotaxin-3 Gene by CREB-binding Protein-mediated Histone 3 Acetylation. Journal of Biological Chemistry 286:15, pages 13193-13204.
Crossref
Crossref
Cindy Davis & Sharon Ross. 2010. Nutrition, Epigenetic Mechanisms, and Human Disease. Nutrition, Epigenetic Mechanisms, and Human Disease
77
108
.
Chung Soo Lee, Jae Chon Yang, Yun Jeong Kim, Eun-Ra Jang, Wonyong Kim & Soon Chul Myung. (2010) 18β-Glycyrrhetinic acid potentiates apoptotic effect of trichostatin A on human epithelial ovarian carcinoma cell lines. European Journal of Pharmacology 649:1-3, pages 354-361.
Crossref
Crossref
Annette Altmann, Michael Eisenhut, Ulrike Bauder-Wüst, Annette Markert, Vasileios Askoxylakis, Holger Hess-Stumpp & Uwe Haberkorn. (2010) Therapy of thyroid carcinoma with the histone deacetylase inhibitor MS-275. European Journal of Nuclear Medicine and Molecular Imaging 37:12, pages 2286-2297.
Crossref
Crossref
Shaoteng Han, Takuya Fukazawa, Tomoki Yamatsuji, Junji Matsuoka, Hiroyuki Miyachi, Yutaka Maeda, Mary Durbin & Yoshio Naomoto. (2010) Anti-Tumor Effect in Human Lung Cancer by a Combination Treatment of Novel Histone Deacetylase Inhibitors: SL142 or SL325 and Retinoic Acids. PLoS ONE 5:11, pages e13834.
Crossref
Crossref
Susan C. Modesitt & Sarah J. Parsons. (2010) In vitro and in vivo histone deacetylase inhibitor therapy with vorinostat and paclitaxel in ovarian cancer models: Does timing matter?. Gynecologic Oncology 119:2, pages 351-357.
Crossref
Crossref
Sandeep Singh, Jackie Johnson & Srikumar Chellappan. (2010) Small molecule regulators of Rb–E2F pathway as modulators of transcription. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1799:10-12, pages 788-794.
Crossref
Crossref
José A. Souto, Esther Vaz, Ilaria Lepore, Ann-Christin Pöppler, Gianluigi Franci, Rosana Álvarez, Lucia Altucci & Ángel R. de Lera. (2010) Synthesis and Biological Characterization of the Histone Deacetylase Inhibitor Largazole and C7- Modified Analogues. Journal of Medicinal Chemistry 53:12, pages 4654-4667.
Crossref
Crossref
Chung Soo Lee, Eun-Ra Jang, Yun Jeong Kim, Soon Chul Myung & Wonyong Kim. (2009) Casein kinase 2 inhibition differentially modulates apoptotic effect of trichostatin A against epithelial ovarian carcinoma cell lines. Molecular and Cellular Biochemistry 338:1-2, pages 157-166.
Crossref
Crossref
Wei-Gang Tong, Yue Wei, William Stevenson, Shao-Qing Kuang, Zhihong Fang, Ming Zhang, Janine Arts & Guillermo Garcia-Manero. (2010) Preclinical antileukemia activity of JNJ-26481585, a potent second-generation histone deacetylase inhibitor. Leukemia Research 34:2, pages 221-228.
Crossref
Crossref
Charles S. DietrichIIIIII, Victoria L. Greenberg, Christopher P. DeSimone, Susan C. Modesitt, John R. van Nagell, Rolf Craven & Stephen G. Zimmer. (2010) Suberoylanilide hydroxamic acid (SAHA) potentiates paclitaxel-induced apoptosis in ovarian cancer cell lines. Gynecologic Oncology 116:1, pages 126-130.
Crossref
Crossref
Sharon A. Ross. 2010. Bioactive Compounds and Cancer. Bioactive Compounds and Cancer
101
123
.
. 2009. Nutrients and Epigenetics. Nutrients and Epigenetics
207
227
.
Hui Nian, Barbara Delage, Emily Ho & Roderick H. Dashwood. (2009) Modulation of histone deacetylase activity by dietary isothiocyanates and allyl sulfides: Studies with sulforaphane and garlic organosulfur compounds. Environmental and Molecular Mutagenesis 50:3, pages 213-221.
Crossref
Crossref
Shiyu Song, Paul Dent & Steven Grant. 2009. The Impact of Tumor Biology on Cancer Treatment and Multidisciplinary Strategies. The Impact of Tumor Biology on Cancer Treatment and Multidisciplinary Strategies
191
219
.
J. S. Bates, D. B. Petry, J. Eudy, L. Bough & R. K. Johnson. (2008) Differential expression in lung and bronchial lymph node of pigs with high and low responses to infection with porcine reproductive and respiratory syndrome virus1,2. Journal of Animal Science 86:12, pages 3279-3289.
Crossref
Crossref
Nataly Tarasenko, Abraham Nudelman, Igor Tarasenko, Michal Entin-Meer, Daphne Hass-Kogan, Aida Inbal & Ada Rephaeli. (2008) Histone deacetylase inhibitors: the anticancer, antimetastatic and antiangiogenic activities of AN-7 are superior to those of the clinically tested AN-9 (Pivanex). Clinical & Experimental Metastasis 25:7, pages 703-716.
Crossref
Crossref
Cesare Gridelli, Antonio Rossi & Paolo Maione. (2008) The potential role of histone deacetylase inhibitors in the treatment of non-small-cell lung cancer. Critical Reviews in Oncology/Hematology 68:1, pages 29-36.
Crossref
Crossref
Degui Wang, Zhiping Wang, Binqiang Tian, Xiaoming Li, Shigang Li & Yingxia Tian. (2008) Two hour exposure to sodium butyrate sensitizes bladder cancer to anticancer drugs. International Journal of Urology 15:5, pages 435-441.
Crossref
Crossref
Guillermina Estiu, Edward Greenberg, Christopher B. Harrison, Nicholas P. Kwiatkowski, Ralph Mazitschek, James E. Bradner & Olaf Wiest. (2008) Structural Origin of Selectivity in Class II-Selective Histone Deacetylase Inhibitors. Journal of Medicinal Chemistry 51:10, pages 2898-2906.
Crossref
Crossref
Ming-Tsung Lai, Chuan-Ching Yang, Tsai-Yun Lin, Fuu-Jen Tsai & Wen-Chi Chen. (2008) Depsipeptide (FK228) inhibits growth of human prostate cancer cells. Urologic Oncology: Seminars and Original Investigations 26:2, pages 182-189.
Crossref
Crossref
Sudhakar Ammanamanchi & Michael G. Brattain. 2008. Transforming Growth Factor-β in Cancer Therapy, Volume II. Transforming Growth Factor-β in Cancer Therapy, Volume II
463
474
.
Diana Blank-Porat, Tal Gruss-Fischer, Nataly Tarasenko, Zvi Malik, Abraham Nudelman & Ada Rephaeli. (2007) The anticancer prodrugs of butyric acid AN-7 and AN-9, possess antiangiogenic properties. Cancer Letters 256:1, pages 39-48.
Crossref
Crossref
Sharon A Ross & John A Milner. (2007) Epigenetic modulation and cancer: effect of metabolic syndrome?. The American Journal of Clinical Nutrition 86:3, pages 872S-877S.
Crossref
Crossref
Chin-Lin Hsu, Wen-Hsieh Lo & Gow-Chin Yen. (2007) Gallic Acid Induces Apoptosis in 3T3-L1 Pre-adipocytes via a Fas- and Mitochondrial-Mediated Pathway. Journal of Agricultural and Food Chemistry 55:18, pages 7359-7365.
Crossref
Crossref
Holger Hess-Stumpp, Tomke Ute Bracker, David Henderson & Oliver Politz. (2007) MS-275, a potent orally available inhibitor of histone deacetylases—The development of an anticancer agent. The International Journal of Biochemistry & Cell Biology 39:7-8, pages 1388-1405.
Crossref
Crossref
Daniel Riester, Christian Hildmann & Andreas Schwienhorst. (2007) Histone deacetylase inhibitors—turning epigenic mechanisms of gene regulation into tools of therapeutic intervention in malignant and other diseases. Applied Microbiology and Biotechnology 75:3, pages 499-514.
Crossref
Crossref
Rino RagnoSilvia SimeoniSabrina CastellanoCaterina VicidominiAntonello MaiAntonella CaroliAnna TramontanoClaudia BonacciniPatrick TrojerIngo BauerGerald BroschGianluca Sbardella. (2007) Small Molecule Inhibitors of Histone Arginine Methyltransferases: Homology Modeling, Molecular Docking, Binding Mode Analysis, and Biological Evaluations. Journal of Medicinal Chemistry 50:6, pages 1241-1253.
Crossref
Crossref
Amy L. Cooper, Victoria L. Greenberg, Pamela S. Lancaster, John R. van NagellJr.Jr., Stephen G. Zimmer & Susan C. Modesitt. (2007) In vitro and in vivo histone deacetylase inhibitor therapy with suberoylanilide hydroxamic acid (SAHA) and paclitaxel in ovarian cancer. Gynecologic Oncology 104:3, pages 596-601.
Crossref
Crossref
Daniel Riester, Christian Hildmann, Andreas Schwienhorst & Franz-Josef Meyer-Almes. (2007) Histone deacetylase inhibitor assay based on fluorescence resonance energy transfer. Analytical Biochemistry 362:1, pages 136-141.
Crossref
Crossref
Kristin Moreth, Daniel Riester, Christian Hildmann, René Hempel, Dennis Wegener, Andreas Schober & Andreas Schwienhorst. (2007) An active site tyrosine residue is essential for amidohydrolase but not for esterase activity of a class 2 histone deacetylase-like bacterial enzyme. Biochemical Journal 401:3, pages 659-665.
Crossref
Crossref
Songyan Han, Jun Lu, Yu Zhang, Cao Cheng, Lin Li, Liping Han & Baiqu Huang. (2007) HDAC inhibitors TSA and sodium butyrate enhanced the human IL-5 expression by altering histone acetylation status at its promoter region. Immunology Letters 108:2, pages 143-150.
Crossref
Crossref
Erica Rockabrand, Natalia Slepko, Antonello Pantalone, Vidya N. Nukala, Aleksey Kazantsev, J. Lawrence Marsh, Patrick G. Sullivan, Joan S. Steffan, Stefano L. Sensi & Leslie Michels Thompson. (2007) The first 17 amino acids of Huntingtin modulate its sub-cellular localization, aggregation and effects on calcium homeostasis. Human Molecular Genetics 16:1, pages 61-77.
Crossref
Crossref
Paul Dent, David T. Curiel & Paul B. Fisher. 2007. Apoptosis, Senescence, and Cancer. Apoptosis, Senescence, and Cancer
281
298
.
Sandeep Akare, Samira Jean-Louis, Wemin Chen, Daniel J. Wood, Ashley A. Powell & Jesse D. Martinez. (2006) Ursodeoxycholic acid modulates histone acetylation and induces differentiation and senescence. International Journal of Cancer 119:12, pages 2958-2969.
Crossref
Crossref
Jin Woong CHUNG, Jun-Ho JEON, Suk-Ran YOON & Inpyo CHOI. (2006)
Vitamin D
3
upregulated protein 1 (VDUP1) is a regulator for redox signaling and stress-mediated diseases
. The Journal of Dermatology 33:10, pages 662-669.
Crossref
Crossref
Dikla Engel, Abraham Nudelman, Inesa Levovich, Tal Gruss-Fischer, Michal Entin-Meer, Don R. Phillips, Suzanne M. Cutts & Ada Rephaeli. (2006) Mode of interaction between butyroyloxymethyl-diethyl phosphate (AN-7) and doxorubicin in MCF-7 and resistant MCF-7/Dx cell lines. Journal of Cancer Research and Clinical Oncology 132:10, pages 673-683.
Crossref
Crossref
Ada Rephaeli, Michal Entin-Meer, Dikla Angel, Nataly Tarasenko, Tal Gruss-Fischer, Irena Bruachman, Don R. Phillips, Suzanne M. Cutts, Daphne Haas-Kogan & Abraham Nudelman. (2006) The selectivty and anti-metastatic activity of oral bioavailable butyric acid prodrugs. Investigational New Drugs 24:5, pages 383-392.
Crossref
Crossref
Adisa Causevic, Marie-Véronique Gentil, Alain Delaunay, Walid Abu El-Soud, Zacarias Garcia, Christophe Pannetier, Franck Brignolas, Daniel Hagège & Stéphane Maury. (2006) Relationship between DNA methylation and histone acetylation levels, cell redox and cell differentiation states in sugarbeet lines. Planta 224:4, pages 812-827.
Crossref
Crossref
Wafik S. El-Deiry, Caroline C. Sigman & Gary J. Kelloff. (2006) Imaging and Oncologic Drug Development. Journal of Clinical Oncology 24:20, pages 3261-3273.
Crossref
Crossref
Z. Alexander Cao, Kathryn E. Bass, Sriram Balasubramanian, Liang Liu, Brian Schultz, Erik Verner, YuQin Dai, Rafael A. Molina, Jack R. Davis, Shawn Misialek, Martin Sendzik, Christine J. Orr, Ling Leung, Ondine Callan, Peter Young, Stacie A. Dalrymple & Joseph J. Buggy. (2006)
CRA-026440: a potent, broad-spectrum, hydroxamic histone deacetylase inhibitor with antiproliferative and antiangiogenic activity
in vitro
and
in vivo
. Molecular Cancer Therapeutics 5:7, pages 1693-1701.
Crossref
Crossref
Christian Hildmann, Dennis Wegener, Daniel Riester, René Hempel, Andreas Schober, Joachim Merana, Laura Giurato, Salvatore Guccione, Tine Kragh Nielsen, Ralf Ficner & Andreas Schwienhorst. (2006) Substrate and inhibitor specificity of class 1 and class 2 histone deacetylases. Journal of Biotechnology 124:1, pages 258-270.
Crossref
Crossref
Melinda C. Myzak, Emily Ho & Roderick H. Dashwood. (2006) Dietary agents as histone deacetylase inhibitors. Molecular Carcinogenesis 45:6, pages 443-446.
Crossref
Crossref
Melinda C. Myzak, Karin Hardin, Rong Wang, Roderick H. Dashwood & Emily Ho. (2006) Sulforaphane inhibits histone deacetylase activity in BPH-1, LnCaP and PC-3 prostate epithelial cells. Carcinogenesis 27:4, pages 811-819.
Crossref
Crossref
Pedro Miura & Bernard J. Jasmin. (2006) Utrophin upregulation for treating Duchenne or Becker muscular dystrophy: how close are we?. Trends in Molecular Medicine 12:3, pages 122-129.
Crossref
Crossref
Paul A. Marks. 2006. Apoptosis and Cancer Therapy. Apoptosis and Cancer Therapy
1014
1032
.
Roderick H. Dashwood, Melinda C. Myzak & Emily Ho. (2006) Dietary HDAC inhibitors: time to rethink weak ligands in cancer chemoprevention?. Carcinogenesis 27:2, pages 344-349.
Crossref
Crossref
Hiroshi Okamoto, Yoshio Fujioka, Akihiro Takahashi, Tomosaburo Takahashi, Takahiro Taniguchi, Yuichi Ishikawa & Mitsuhiro Yokoyama. (2006) Trichostatin A, an Inhibitor of Histone Deacetylase, Inhibits Smooth Muscle Cell Proliferation via Induction of p21WAF1. Journal of Atherosclerosis and Thrombosis 13:4, pages 183-191.
Crossref
Crossref
Michal Entin-Meer, Ada Rephaeli, Xiaodong Yang, Abraham Nudelman, Scott R. VandenBerg & Daphne Adele Haas-Kogan. (2005) Butyric acid prodrugs are histone deacetylase inhibitors that show antineoplastic activity and radiosensitizing capacity in the treatment of malignant gliomas. Molecular Cancer Therapeutics 4:12, pages 1952-1961.
Crossref
Crossref
Søren Skov, Marianne Terndrup Pedersen, Lars Andresen, Per Thor Straten, Anders Woetmann & Niels Ødum. (2005) Cancer Cells Become Susceptible to Natural Killer Cell Killing after Exposure to Histone Deacetylase Inhibitors Due to Glycogen Synthase Kinase-3–Dependent Expression of MHC Class I–Related Chain A and B. Cancer Research 65:23, pages 11136-11145.
Crossref
Crossref
Roberto R. Rosato, Jorge A. Almenara, Sonia C. Maggio, Peter Atadja, Ruth Craig, Julie Vrana, Paul Dent & Steven Grant. (2005) Potentiation of the lethality of the histone deacetylase inhibitor LAQ824 by the cyclin-dependent kinase inhibitor roscovitine in human leukemia cells. Molecular Cancer Therapeutics 4:11, pages 1772-1785.
Crossref
Crossref
Susana B. Bravo, María E.R. García-Rendueles, Rafael Seoane, Vanesa Dosil, José Cameselle-Teijeiro, Luis López-Lázaro, Juan Zalvide, Francisco Barreiro, Celia M. Pombo & Clara V. Álvarez. (2005) Plitidepsin Has a Cytostatic Effect in Human Undifferentiated (Anaplastic) Thyroid Carcinoma. Clinical Cancer Research 11:21, pages 7664-7673.
Crossref
Crossref
Tine Kragh Nielsen, Christian Hildmann, Achim Dickmanns, Andreas Schwienhorst & Ralf Ficner. (2005) Crystal Structure of a Bacterial Class 2 Histone Deacetylase Homologue. Journal of Molecular Biology 354:1, pages 107-120.
Crossref
Crossref
Milos Dokmanovic & Paul A. Marks. (2005) Prospects: Histone deacetylase inhibitors. Journal of Cellular Biochemistry 96:2, pages 293-304.
Crossref
Crossref
Ada Rephaeli, Diana Blank-Porat, Nataly Tarasenko, Michal Entin-Meer, Inesa Levovich, Suzanne M. Cutts, Don R. Phillips, Zvi Malik & Abraham Nudelman. (2005) In vivo andin vitro antitumor activity of butyroyloxymethyl-diethyl phosphate (AN-7), a histone deacetylase inhibitor, in human prostate cancer. International Journal of Cancer 116:2, pages 226-235.
Crossref
Crossref
Mikhail V. Blagosklonny, Shana Trostel, Ganesh Kayastha, Zoya N. Demidenko, Lyubomir T. Vassilev, Larisa Y. Romanova, Susan Bates & Tito Fojo. (2005) Depletion of Mutant p53 and Cytotoxicity of Histone Deacetylase Inhibitors. Cancer Research 65:16, pages 7386-7392.
Crossref
Crossref
Pilar García-Morales, Angeles Gómez-Martínez, Alfredo Carrato, Isabel Martínez-Lacaci, Víctor M. Barberá, José L. Soto, Estefanía Carrasco-García, María P. Menéndez-Gutierrez, María D. Castro-Galache, José A. Ferragut & Miguel Saceda. (2005) Histone deacetylase inhibitors induced caspase-independent apoptosis in human pancreatic adenocarcinoma cell lines. Molecular Cancer Therapeutics 4:8, pages 1222-1230.
Crossref
Crossref
Thiyam Ramsing Singh, Sharmila Shankar & Rakesh K Srivastava. (2005) HDAC inhibitors enhance the apoptosis-inducing potential of TRAIL in breast carcinoma. Oncogene 24:29, pages 4609-4623.
Crossref
Crossref
Anupama Munshi, John F. Kurland, Takashi Nishikawa, Toshimitsu Tanaka, Marvette L. Hobbs, Susan L. Tucker, Sheikh Ismail, Craig Stevens & Raymond E. Meyn. (2005) Histone Deacetylase Inhibitors Radiosensitize Human Melanoma Cells by Suppressing DNA Repair Activity. Clinical Cancer Research 11:13, pages 4912-4922.
Crossref
Crossref
Ana M. Aparicio, Anthony B. Elkhouiery & David I. Quinn. (2005) The Current and Future Application of Adjuvant Systemic Chemotherapy in Patients with Bladder Cancer Following Cystectomy. Urologic Clinics of North America 32:2, pages 217-230.
Crossref
Crossref
Antonello Mai, Silvio Massa, Dante Rotili, Ilaria Cerbara, Sergio Valente, Riccardo Pezzi, Silvia Simeoni & Rino Ragno. (2005) Histone deacetylation in epigenetics: An attractive target for anticancer therapy. Medicinal Research Reviews 25:3, pages 261-309.
Crossref
Crossref
Abraham NudelmanInesa LevovichSuzanne M. CuttsDon R. PhillipsAda Rephaeli. (2005) The Role of Intracellularly Released Formaldehyde and Butyric Acid in the Anticancer Activity of Acyloxyalkyl Esters. Journal of Medicinal Chemistry 48:4, pages 1042-1054.
Crossref
Crossref
Paul Marks & William Kevin Kelly. 2005. DNA Methylation, Epigenetics and Metastasis. DNA Methylation, Epigenetics and Metastasis
269
305
.
Jiuhong Kang, Jie Chen, Dawei Zhang, Wanming Da & Yingxian Ou. (2004) Synergistic killing of human leukemia cells by antioxidants and trichostatin A. Cancer Chemotherapy and Pharmacology 54:6, pages 537-545.
Crossref
Crossref
Hidefumi Sasaki, Satoru Moriyama, Yoshiaki Nakashima, Yoshihiro Kobayashi, Masanobu Kiriyama, Ichiro Fukai, Yosuke Yamakawa & Yoshitaka Fujii. (2004) Histone deacetylase 1 mRNA expression in lung cancer. Lung Cancer 46:2, pages 171-178.
Crossref
Crossref
Tania M. Schroeder, Rachel A. Kahler, Xiaodong Li & Jennifer J. Westendorf. (2004) Histone Deacetylase 3 Interacts with Runx2 to Repress the Osteocalcin Promoter and Regulate Osteoblast Differentiation. Journal of Biological Chemistry 279:40, pages 41998-42007.
Crossref
Crossref
Keiichiro Nishida, Takamitsu Komiyama, Shin‐ichi Miyazawa, Zheng‐Nan Shen, Takayuki Furumatsu, Hideyuki Doi, Aki Yoshida, Jiro Yamana, Masahiro Yamamura, Yoshihumi Ninomiya, Hajime Inoue & Hiroshi Asahara. (2004)
Histone deacetylase inhibitor suppression of autoantibody‐mediated arthritis in mice via regulation of p16
INK4a
and p21
WAF1/Cip1
expression
. Arthritis & Rheumatism 50:10, pages 3365-3376.
Crossref
Crossref
Melinda C. Myzak, P. Andrew Karplus, Fung-Lung Chung & Roderick H. Dashwood. (2004) A Novel Mechanism of Chemoprotection by Sulforaphane. Cancer Research 64:16, pages 5767-5774.
Crossref
Crossref
Angela Brieger, Simone Boehrer, Simone Schaaf, Daniel Nowak, Martin Ruthardt, Soo-Zin Kim, Peter Atadja, Dieter Hoelzer, Paris S Mitrou, Eckhart Weidmann & Kai Uwe Chow. (2004) In bcr-abl-positive myeloid cells resistant to conventional chemotherapeutic agents, expression of Par-4 increases sensitivity to imatinib (STI571) and histone deacetylase-inhibitors. Biochemical Pharmacology 68:1, pages 85-93.
Crossref
Crossref
Xin-Yan Pei, Yun Dai & Steven Grant. (2004) Synergistic Induction of Oxidative Injury and Apoptosis in Human Multiple Myeloma Cells by the Proteasome Inhibitor Bortezomib and Histone Deacetylase Inhibitors. Clinical Cancer Research 10:11, pages 3839-3852.
Crossref
Crossref
IvanV Gregoretti, Yun-Mi Lee & Holly V Goodson. (2004) Molecular Evolution of the Histone Deacetylase Family: Functional Implications of Phylogenetic Analysis. Journal of Molecular Biology 338:1, pages 17-31.
Crossref
Crossref
Dimitrios Zgouras, Ute Becker, Stefan Loitsch & Jürgen Stein. (2004) Modulation of angiogenesis-related protein synthesis by valproic acid. Biochemical and Biophysical Research Communications 316:3, pages 693-697.
Crossref
Crossref
Marcus Schuchmann & Peter R Galle. (2004) Sensitizing to apoptosis—sharpening the medical sword. Journal of Hepatology 40:2, pages 335-336.
Crossref
Crossref
Masataka Hoshino, Kazuhiko Tagawa, Tomohiro Okuda, Miho Murata, Kiyomitsu Oyanagi, Nobutaka Arai, Toshio Mizutani, Ichiro Kanazawa, Erich E. Wanker & Hitoshi Okazawa. (2003) Histone deacetylase activity is retained in primary neurons expressing mutant huntingtin protein. Journal of Neurochemistry 87:1, pages 257-267.
Crossref
Crossref