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Cancer Biology & Therapy Volume 13, 2012 - Issue 12
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Research Paper

CDX2 serves as a Wnt signaling inhibitor and is frequently methylated in lung cancer

Xuefeng Liu Department of Gastroenterology and Hepatology; Chinese PLA General Hospital; Beijing, China; State Key Laboratory of Molecular Oncology; Cancer Institute and Cancer Hospital; Chinese Academy of Medical Sciences and Peking Union Medical College; Beijing, China
,
Xiaomei Zhang Department of Gastroenterology and Hepatology; Chinese PLA General Hospital; Beijing, China
,
Qimin Zhan State Key Laboratory of Molecular Oncology; Cancer Institute and Cancer Hospital; Chinese Academy of Medical Sciences and Peking Union Medical College; Beijing, China
,
Malcolm V. Brock The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins; The Bunting-Blaustein Cancer Research Building; Baltimore, MD USA
,
James G. Herman The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins; The Bunting-Blaustein Cancer Research Building; Baltimore, MD USACorrespondence[email protected] [email protected]
&
Mingzhou Guo Department of Gastroenterology and Hepatology; Chinese PLA General Hospital; Beijing, ChinaCorrespondence[email protected] [email protected]
Pages 1152-1157 | Received 12 Mar 2012, Accepted 03 Jul 2012, Published online: 23 Aug 2012

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Amit Kumar, Ravindra B. Chalamalasetty, Mark W. Kennedy, Sara Thomas, Shreya N. Inala, Robert J. Garriock & Terry P. Yamaguchi. (2016) Zfp703 Is a Wnt/β-Catenin Feedback Suppressor Targeting the β-Catenin/Tcf1 Complex. Molecular and Cellular Biology 36:12, pages 1793-1802.
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Articles from other publishers (13)

Hongxia Li, Weili Yang, Meiying Zhang, Tao He, Fuyou Zhou, James G Herman, Liming Hu & Mingzhou Guo. (2021) Methylation of TMEM176A , a key ERK signaling regulator, is a novel synthetic lethality marker of ATM inhibitors in human lung cancer . Epigenomics 13:17, pages 1403-1419.
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Aiai Gao & Mingzhou Guo. (2020) Epigenetic based synthetic lethal strategies in human cancers. Biomarker Research 8:1.
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Qiyu Tian, Zhixin Xu, Xiaofei Sun, Jeanene Deavila, Min Du & Meijun Zhu. (2020) Grape pomace inhibits colon carcinogenesis by suppressing cell proliferation and inducing epigenetic modifications. The Journal of Nutritional Biochemistry 84, pages 108443.
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Chang Feng, Man Feng, Yujun Gao, Xiaogang Zhao, Chuanliang Peng, Xiangshan Yang & Jing Zhang. (2019) Clinicopathologic Significance of Intestinal-type Molecules’ Expression and Different EGFR Gene Status in Pulmonary Adenocarcinoma. Applied Immunohistochemistry & Molecular Morphology 27:5, pages 364-372.
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Hong-Bin Wang, Hong Wei, Jin-Song Wang, Lin Li, An-Yue Chen & Zhi-Gao Li. (2019) Down-regulated expression of LINC00518 prevents epithelial cell growth and metastasis in breast cancer through the inhibition of CDX2 methylation and the Wnt signaling pathway. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1865:3, pages 708-723.
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Junhui Yu, Dong Liu, Xuejun Sun, Kui Yang, Jianfeng Yao, Chen Cheng, Chunbao Wang & Jianbao Zheng. (2019) CDX2 inhibits the proliferation and tumor formation of colon cancer cells by suppressing Wnt/β-catenin signaling via transactivation of GSK-3β and Axin2 expression. Cell Death & Disease 10:1.
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Dabeiba Adriana García Robayo, Diego Andres Castañeda, Juvenal Dario Baena, Angel Cid Arregui & Fabio Ancizar Aristizabal. (2018) Expresión de EDNRB y CDX2 posibles biomarcadores en progresión al cáncer cervical. Revista Colombiana de Biotecnología 20:1, pages 6-15.
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Kevin Tong, Oscar Pellón-Cárdenas, Veerin R. Sirihorachai, Bailey N. Warder, Om A. Kothari, Ansu O. Perekatt, Emily E. Fokas, Robert L. Fullem, Anbo Zhou, Joshua K. Thackray, Hiep Tran, Lanjing Zhang, Jinchuan Xing & Michael P. Verzi. (2017) Degree of Tissue Differentiation Dictates Susceptibility to BRAF-Driven Colorectal Cancer. Cell Reports 21:13, pages 3833-3845.
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Matthias Lienhard, Sabrina Grasse, Jana Rolff, Steffen Frese, Uwe Schirmer, Michael Becker, Stefan Börno, Bernd Timmermann, Lukas Chavez, Holger Sültmann, Gunda Leschber, Iduna Fichtner, Michal R Schweiger & Ralf Herwig. (2017) QSEA—modelling of genome-wide DNA methylation from sequencing enrichment experiments. Nucleic Acids Research 45:6, pages e44-e44.
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Renhua Song, Daniel R. Catchpoole, Paul J. Kennedy & Jinyan Li. (2015) Identification of lung cancer miRNA–miRNA co-regulation networks through a progressive data refining approach. Journal of Theoretical Biology 380, pages 271-279.
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Kausilia K. Krishnadath & Kenneth K. Wang. (2015) Molecular Pathogenesis of Barrett Esophagus. Gastroenterology Clinics of North America 44:2, pages 233-247.
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D. J. Stewart. (2013) Wnt Signaling Pathway in Non-Small Cell Lung Cancer. JNCI Journal of the National Cancer Institute 106:1, pages djt356-djt356.
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Guang-Xi Zhou, Xiao-Yu Li, Qi Zhang, Kun Zhao, Cui-Ping Zhang, Chang-Hu Xue, Kun Yang & Zi-Bin Tian. (2013) Effects of the Hippo Signaling Pathway in Human Gastric Cancer. Asian Pacific Journal of Cancer Prevention 14:9, pages 5199-5205.
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