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Cancer Biology & Therapy Volume 14, 2013 - Issue 9
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Research Paper

Combination treatment of PD98059 and DAPT in gastric cancer through induction of apoptosis and downregulation of WNT/β-catenin

Jun Yao Institute of Tumor; School of Medicine; Taizhou University; Taizhou, Zhejiang P.R. China
,
Cuijuan Qian Insitute of Gastroenterology; Sir Run Run Shaw Hospital; Zhejiang University; Hangzhou, Zhejiang P.R. China
,
Ting Shu Institute of Tumor; School of Medicine; Taizhou University; Taizhou, Zhejiang P.R. China
,
Xin Zhang Department of Gastroenterology; Taizhou Municipal Hospital; Taizhou, Zhejiang P.R. China
,
Zhiqiang Zhao Institute of Tumor; School of Medicine; Taizhou University; Taizhou, Zhejiang P.R. China
&
Yong Liang Institute of Tumor; School of Medicine; Taizhou University; Taizhou, Zhejiang P.R. ChinaCorrespondence[email protected]
Pages 833-839 | Received 05 May 2013, Accepted 08 Jun 2013, Published online: 14 Jun 2013

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Atul Kumar Singh & Shashank Kumar. (2023) Flavonoids as emerging notch signaling pathway modulators in cancer. Journal of Asian Natural Products Research 0:0, pages 1-13.
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Afsane Bahrami & Gordon A. Ferns. (2021) Effect of Curcumin and Its Derivates on Gastric Cancer: Molecular Mechanisms. Nutrition and Cancer 73:9, pages 1553-1569.
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Paul Dent. (2013) HDACIs and the inhibition of invasive potential. Cancer Biology & Therapy 14:9, pages 776-777.
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Elham Patrad, Ali Niapour, Faris Farassati & Mojtaba Amani. (2018) Combination treatment of all-trans retinoic acid (ATRA) and γ-secretase inhibitor (DAPT) cause growth inhibition and apoptosis induction in the human gastric cancer cell line. Cytotechnology 70:2, pages 865-877.
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Li Hou, Xiaofei Hou, Lijing Wang, Zenghui Li, Beibei Xin, Jing Chen, Xiaofei Gao & Haixia Mu. (2017) PD98059 impairs the cisplatin-resistance of ovarian cancer cells by suppressing ERK pathway and epithelial mesenchymal transition process. Cancer Biomarkers 21:1, pages 187-194.
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Shivaani KummarGeraldine O'Sullivan CoyneKhanh T. DoBaris TurkbeyPaul S. MeltzerEric PolleyPeter L. ChoykeRobert MeehanRasa VilimasYvonne HornefferLamin JuwaraAnn LihAmul ChoudharySandra A. MitchellLee J. HelmanJames H. DoroshowAlice P. Chen. (2017) Clinical Activity of the γ-Secretase Inhibitor PF-03084014 in Adults With Desmoid Tumors (Aggressive Fibromatosis). Journal of Clinical Oncology 35:14, pages 1561-1569.
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Xiao-Mei Mao, Qi-Rui Fu, Hua-Liang Li, Ya-Hui Zheng, Shu-Ming Chen, Xin-Yi Hu, Qing-Xi Chen & Qiong-Hua Chen. (2017) Crocodile choline from Crocodylus siamensis induces apoptosis of human gastric cancer . Tumor Biology 39:3, pages 101042831769432.
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Jiawei Guo, Weiwei Yu, Hui Su & Xiufeng Pang. (2016) Genomic landscape of gastric cancer: molecular classification and potential targets. Science China Life Sciences 60:2, pages 126-137.
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Xiaoyu Wu, Wentao Liu, Ding Tang, Haijuan Xiao, Zhenfeng Wu, Che Chen, Xuequan Yao, Fukun Liu & Gang Li. (2016) Prognostic values of four Notch receptor mRNA expression in gastric cancer. Scientific Reports 6:1.
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Timur Saliev, Loreto B. Feril Jr., Koichi Ogawa, Akiko Watanabe, Dinara Begimbetova, Askhat Molkenov, Dauren Alimbetov & Katsuro Tachibana. (2016) Induction of Apoptosis in U937 Cells by Using a Combination of Bortezomib and Low-Intensity Ultrasound. Medical Science Monitor 22, pages 5049-5057.
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Xun Yuan, Hua Wu, Hanxiao Xu, Huihua Xiong, Qian Chu, Shiying Yu, Gen Sheng Wu & Kongming Wu. (2015) Notch signaling: An emerging therapeutic target for cancer treatment. Cancer Letters 369:1, pages 20-27.
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Hui Shang, Danielle Braggio, Ya‐Jung Lee, Ghadah A. Al Sannaa, Chad J. Creighton, Svetlana Bolshakov, Alexander J. F. Lazar, Dina Lev & Raphael E. Pollock. (2015) Targeting the N otch pathway: A potential therapeutic approach for desmoid tumors . Cancer 121:22, pages 4088-4096.
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Miguel Angel Chiurillo. (2015) Role of the Wnt/β-catenin pathway in gastric cancer: An in-depth literature review. World Journal of Experimental Medicine 5:2, pages 84.
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Mei Hu, Hai-Feng Ou-Yang, Chang-Gui Wu, Shuo-Yao Qu, Xin-Ting Xu & Ping Wang. (2014) Notch signaling regulates col1α1 and col1α2 expression in airway fibroblasts. Experimental Biology and Medicine 239:12, pages 1589-1596.
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Suruchi Mittal, Ankur Sharma, Sai A. Balaji, Manju C. Gowda, Rajan R. Dighe, Rekha V. Kumar & Annapoorni Rangarajan. (2014) Coordinate Hyperactivation of Notch1 and Ras/MAPK Pathways Correlates with Poor Patient Survival: Novel Therapeutic Strategy for Aggressive Breast Cancers. Molecular Cancer Therapeutics 13:12, pages 3198-3209.
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Michael Kahn. (2014) Can we safely target the WNT pathway?. Nature Reviews Drug Discovery 13:7, pages 513-532.
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Emma R. Andersson & Urban Lendahl. (2014) Therapeutic modulation of Notch signalling — are we there yet?. Nature Reviews Drug Discovery 13:5, pages 357-378.
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Zhongchuan WangJiwei SunXuguang HuShiyong Huang. (2014) Interference of Mucin 1 Inhibits Progression of Colon Carcinoma by Repression of Wnt/β-Catenin Signaling . DNA and Cell Biology 33:3, pages 162-170.
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