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Research Paper

Dysregulation of the mTOR pathway in p53-deficient mice

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Pages 1182-1188 | Received 14 Oct 2013, Accepted 24 Oct 2013, Published online: 01 Nov 2013

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Song Yang, Gaohua Han, Quan Chen, Lei Yu, Peng Wang, Qi Zhang, Jiang Dong, Wei Zhang & Junxing Huang. (2021) Au-Pt Nanoparticle Formulation as a Radiosensitizer for Radiotherapy with Dual Effects. International Journal of Nanomedicine 16, pages 239-248.
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Mikhail V. Blagosklonny. (2022) As expected, based on rapamycin-like p53-mediated gerosuppression, mTOR inhibition acts as a checkpoint in p53-mediated tumor suppression. Oncoscience 9, pages 38-41.
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Jin Young Lee, Brian K Kennedy & Chen-Yu Liao. (2020) Mechanistic target of rapamycin signaling in mouse models of accelerated aging. The Journals of Gerontology: Series A 75:1, pages 64-72.
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Valentino Bezzerri, Francesco Piacenza, Nicole Caporelli, Marco Malavolta, Mauro Provinciali & Marco Cipolli. (2019) Is cellular senescence involved in cystic fibrosis?. Respiratory Research 20:1.
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Jelena Krstic, Isabel Reinisch, Michael Schupp, Tim Schulz & Andreas Prokesch. (2018) p53 Functions in Adipose Tissue Metabolism and Homeostasis. International Journal of Molecular Sciences 19:9, pages 2622.
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Jin Zining, Xu Lu, He Caiyun & Yuan Yuan. (2016) Genetic polymorphisms of mTOR and cancer risk: a systematic review and updated meta-analysis . Oncotarget 7:35, pages 57464-57480.
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Olga V. Leontieva, Zoya N. Demidenko & Mikhail V. Blagosklonny. (2015) Dual mTORC1/C2 inhibitors suppress cellular geroconversion (a senescence program). Oncotarget 6:27, pages 23238-23248.
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Yair Argon & Tali Gidalevitz. 2015. Longevity Genes. Longevity Genes 45 72 .
Olga V. Leontieva & Mikhail V. Blagosklonny. (2014) Tumor promoter-induced cellular senescence: cell cycle arrest followed by geroconversion. Oncotarget 5:24, pages 12715-12727.
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Lorena Landuzzi, Marianna L. Ianzano, Giordano Nicoletti, Arianna Palladini, Valentina Grosso, Dario Ranieri, Massimiliano Dall’Ora, Elena Raschi, Roberta Laranga, Marco Gambarotti, Piero Picci, Carla De Giovanni, Patrizia Nanni & Pier-Luigi Lollini. (2014) Genetic prevention of lymphoma in p53 knockout mice allows the early development of p53-related sarcomas. Oncotarget 5:23, pages 11924-11938.
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Olga V. Leontieva, Geraldine M. Paszkiewicz & Mikhail V. Blagosklonny. (2014) Weekly administration of rapamycin improves survival and biomarkers in obese male mice on high‐fat diet. Aging Cell 13:4, pages 616-622.
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Olga V. Leontieva, Zoya N. Demidenko & Mikhail V. Blagosklonny. (2014) Contact inhibition and high cell density deactivate the mammalian target of rapamycin pathway, thus suppressing the senescence program. Proceedings of the National Academy of Sciences 111:24, pages 8832-8837.
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Wei-Lin Liu, Ming Gao, Kai-Yuan Tzen, Chiao-Ling Tsai, Feng-Ming Hsu, Ann-Lii Cheng & Jason Chia-Hsien Cheng. (2014) Targeting Phosphatidylinositide3-Kinase/Akt pathway by BKM120 for radiosensitization in hepatocellular carcinoma. Oncotarget 5:11, pages 3662-3672.
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Tatiana V. Pospelova & Valery A. Pospelov. (2014) Latest progress in tyrosine kinase inhibitors. Oncotarget 5:5, pages 1157-1161.
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