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Cancer Biology & Therapy Volume 15, 2014 - Issue 3
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Research Paper

EZH2 participates in malignant biological behavior of epithelial ovarian cancer through regulating the expression of BRCA1

Tao Li Department of Obstetrics and Gynecology; Union Hospital; Tongji Medical College; Huazhong University of Science and Technology; Wuhan, PR China
,
Jing Cai Department of Obstetrics and Gynecology; Union Hospital; Tongji Medical College; Huazhong University of Science and Technology; Wuhan, PR China
,
Hui Ding Department of Obstetrics and Gynecology; Union Hospital; Tongji Medical College; Huazhong University of Science and Technology; Wuhan, PR China
,
Linjuan Xu Department of Obstetrics and Gynecology; Union Hospital; Tongji Medical College; Huazhong University of Science and Technology; Wuhan, PR China
,
Qiang Yang Department of Obstetrics and Gynecology; Union Hospital; Tongji Medical College; Huazhong University of Science and Technology; Wuhan, PR China
&
Zehua Wang Department of Obstetrics and Gynecology; Union Hospital; Tongji Medical College; Huazhong University of Science and Technology; Wuhan, PR ChinaCorrespondence[email protected]
Pages 271-278 | Received 15 Jun 2013, Accepted 21 Nov 2013, Published online: 12 Dec 2013

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Dongwei Dou, Xin Ge, Xinxing Wang, Xiaodong Xu, Zhe Zhang, Jingjing Seng, Zhang Cao, Yuanting Gu & Mingli Han. (2019) EZH2 Contributes To Cisplatin Resistance In Breast Cancer By Epigenetically Suppressing miR-381 Expression. OncoTargets and Therapy 12, pages 9627-9637.
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Articles from other publishers (20)

Yimeng Zhang, Yuexin Zhang, Chao Song, Xilong Zhao, Bo Ai, Yuezhu Wang, Liwei Zhou, Jiang Zhu, Chenchen Feng, Liyan Xu, Qiuyu Wang, Hong Sun, Qiaoli Fang, Xiaozheng Xu, Enmin Li & Chunquan Li. (2023) CRdb: a comprehensive resource for deciphering chromatin regulators in human. Nucleic Acids Research 51:D1, pages D88-D100.
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Anne-Marie Baird & Steven G. Gray. 2023. Epigenetic Cancer Therapy. Epigenetic Cancer Therapy 577 611 .
Ivana Samaržija, Marko Tomljanović, Renata Novak Kujundžić & Koraljka Gall Trošelj. (2022) EZH2 Inhibition and Cisplatin as a Combination Anticancer Therapy: An Overview of Preclinical Studies. Cancers 14:19, pages 4761.
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Lin Zhao, Hongjie Guo, Xi Chen, Wenxin Zhang, Qiaojun He, Ling Ding & Bo Yang. (2022) Tackling drug resistance in ovarian cancer with epigenetic targeted drugs. European Journal of Pharmacology 927, pages 175071.
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Pengfei Gao, Xin Zeng, Lin Zhang, Long Wang, Lu-Lu Shen, Ya-Yun Hou, Fang Zhou & Xianlong Zhang. (2021) Overexpression of miR-378 Alleviates Chronic Sciatic Nerve Injury by Targeting EZH2. Neurochemical Research 46:12, pages 3213-3221.
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Sarah Brunty, Lauren Clower, Brenda Mitchell, Taylor Fleshman, Nadim Bou Zgheib & Nalini Santanam. (2021) Peritoneal Modulators of Endometriosis-Associated Ovarian Cancer. Frontiers in Oncology 11.
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Roberts, Cardenas & Tedja. (2019) The Role of Intra-Tumoral Heterogeneity and Its Clinical Relevance in Epithelial Ovarian Cancer Recurrence and Metastasis. Cancers 11:8, pages 1083.
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Qilian Yang, Yuqing Yang, Nianxin Zhou, Kexin Tang, Wayne Bond Lau, Bonnie Lau, Wei Wang, Lian Xu, Zhengnan Yang, Shuang Huang, Xin Wang, Tao Yi, Xia Zhao, Yuquan Wei, Hongjing Wang, Linjie Zhao & Shengtao Zhou. (2018) Epigenetics in ovarian cancer: premise, properties, and perspectives. Molecular Cancer 17:1.
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Si Sun, Simei Zhao, Qiang Yang, Wenwen Wang, E Cai, Yiping Wen, Lili Yu, Zehua Wang & Jing Cai. (2018) Enhancer of zeste homolog 2 promotes cisplatin resistance by reducing cellular platinum accumulation. Cancer Science 109:6, pages 1853-1864.
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H Yamaguchi, Y Du, K Nakai, M Ding, S-S Chang, J L Hsu, J Yao, Y Wei, L Nie, S Jiao, W-C Chang, C-H Chen, Y Yu, G N Hortobagyi & M-C Hung. (2017) EZH2 contributes to the response to PARP inhibitors through its PARP-mediated poly-ADP ribosylation in breast cancer. Oncogene 37:2, pages 208-217.
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Margaret Nieborowska-SkorskaSilvia MaifredeYashodhara DasguptaKatherine SullivanSylwia FlisBac Viet LeMartyna SoleckaElizaveta A. BelyaevaLucia KubovcakovaMorgan NawrockiMartin KirschnerHuaqing ZhaoJosef T. PrchalKatarzyna PiwockaAlison R. Moliterno, Mariusz WasikSteffen KoschmiederTony R. Green, Radek C. SkodaTomasz Skorski. (2017) Ruxolitinib-induced defects in DNA repair cause sensitivity to PARP inhibitors in myeloproliferative neoplasms. Blood 130:26, pages 2848-2859.
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Jill K. Alldredge & Ramez N. Eskander. (2017) EZH2 inhibition in ARID1A mutated clear cell and endometrioid ovarian and endometrioid endometrial cancers. Gynecologic Oncology Research and Practice 4:1.
Crossref
Teodora Nikolova, Nicole Kiweler & Oliver H. Krämer. (2017) Interstrand Crosslink Repair as a Target for HDAC Inhibition. Trends in Pharmacological Sciences 38:9, pages 822-836.
Crossref
Xiaoqing Yi, Jianfeng Guo, Jing Guo, Si Sun, Ping Yang, Junjie Wang, Yuan Li, Lisha Xie, Jing Cai & Zehua Wang. (2017) EZH2-mediated epigenetic silencing of TIMP2 promotes ovarian cancer migration and invasion. Scientific Reports 7:1.
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Yuxiang Huang, Xuanyi Wang, Xiaoshuang Niu, Xiaoshen Wang, Rui Jiang, Tingting Xu, Yong Liu, Liping Liang, Xiaomin Ou, Xing Xing, Weiwei Li & Chaosu Hu. (2017) EZH2 suppresses the nucleotide excision repair in nasopharyngeal carcinoma by silencing XPA gene. Molecular Carcinogenesis 56:2, pages 447-463.
Crossref
Shuangping Guo, Xia Li, Joseph Rohr, Yingmei Wang, Shirong Ma, Peng Chen & Zhe Wang. (2016) EZH2 overexpression in different immunophenotypes of breast carcinoma and association with clinicopathologic features. Diagnostic Pathology 11:1.
Crossref
Fenmei Zhou, Juan Chen & Hairong Wang. (2016) MicroRNA-298 inhibits malignant phenotypes of epithelial ovarian cancer by regulating the expression of EZH2. Oncology Letters 12:5, pages 3926-3932.
Crossref
Mónica Martínez-Fernández, Carolina Rubio, Cristina Segovia, Fernando López-Calderón, Marta Dueñas & Jesús Paramio. (2015) EZH2 in Bladder Cancer, a Promising Therapeutic Target. International Journal of Molecular Sciences 16:11, pages 27107-27132.
Crossref
Song Fan, Bodu Liu, Lijuan Sun, Xiao-bin Lv, Zhaoyu Lin, Weixiong Chen, Weiliang Chen, Qionglan Tang, Youyuan Wang, Yuxiong Su, Shaowen Jin, Daming Zhang, Jianglong Zhong, Yilin Li, Bin Wen, Zhang Zhang, Pu Yang, Bin Zhou, Qixiang Liang, Xing Yu, Yinghua Zhu, Pengnan Hu, Junjun Chu, Wei Huang, Yuhuan Feng, Hongzhuang Peng, Qihong Huang, Erwei Song & Jinsong Li. (2015) Mitochondrial fission determines cisplatin sensitivity in tongue squamous cell carcinoma through the BRCA1-miR-593-5p–MFF axis. Oncotarget 6:17, pages 14885-14904.
Crossref
Steven G. Gray. 2015. Epigenetic Cancer Therapy. Epigenetic Cancer Therapy 613 637 .

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