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Cancer Biology & Therapy Volume 15, 2014 - Issue 3

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Research Paper

Overexpression of the pp32r1 (ANP32C) oncogene or its functional mutant pp32r1Y140H confers enhanced resistance to FTY720 (Finguimod)

Salma Buddaseth Institute for Transfusion Medicine; Hannover Medical School; Hannover, Germany

Wiebke Göttmann Institute for Transfusion Medicine; Hannover Medical School; Hannover, Germany

Rainer Blasczyk Institute for Transfusion Medicine; Hannover Medical School; Hannover, Germany

Trevor Huyton Institute for Transfusion Medicine; Hannover Medical School; Hannover, GermanyCorrespondence[email protected]

Pages 289-296 | Received 18 Jul 2013, Accepted 21 Nov 2013, Published online: 12 Dec 2013

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https://doi.org/10.4161/cbt.27307
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Mengmeng Yu, Yuxing Qu, Haili Zhang & Xiaojun Wang. (2022) Roles of ANP32 proteins in cell biology and viral replication. Animal Diseases 2:1.
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Cassandra P. Nader, Aylin Cidem, Nicole M. Verrills & Alaina J. Ammit. (2019) Protein phosphatase 2A (PP2A): a key phosphatase in the progression of chronic obstructive pulmonary disease (COPD) to lung cancer. Respiratory Research 20:1.
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Md. Mostafizur Rahman, Laura Prünte, Leonard F. Lebender, Brijeshkumar S. Patel, Ingrid Gelissen, Philip M. Hansbro, Jonathan C. Morris, Andrew R. Clark, Nicole M. Verrills & Alaina J. Ammit. (2016) The phosphorylated form of FTY720 activates PP2A, represses inflammation and is devoid of S1P agonism in A549 lung epithelial cells. Scientific Reports 6:1.
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Christopher White, Heba Alshaker, Colin Cooper, Matthias Winkler & Dmitri Pchejetski. (2016) The emerging role of FTY720 (Fingolimod) in cancer treatment. Oncotarget 7:17, pages 23106-23127.
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Yuliia Yuzefovych, Rainer Blasczyk & Trevor Huyton. (2015) Oncogenic acidic nuclear phosphoproteins ANP32C/D are novel clients of heat shock protein 90. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1853:10, pages 2338-2348.
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Shanshan Wang, Yunliang Wang, Qingshan Lu, Xinshan Liu, Fuyu Wang, Xiaodong Ma, Chunping Cui, Chenghe Shi, Jinfeng Li & Dajin Zhang. (2015) The Expression and Distributions of ANP32A in the Developing Brain. BioMed Research International 2015, pages 1-8.
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Nikolas K. Haass, Najah Nassif & Eileen M. McGowan. (2015) Switching the Sphingolipid Rheostat in the Treatment of Diabetes and Cancer Comorbidity from a Problem to an Advantage. BioMed Research International 2015, pages 1-9.
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Patrick T. Reilly, Yun Yu, Ali Hamiche & Lishun Wang. (2014) Cracking the ANP32 whips: Important functions, unequal requirement, and hints at disease implications. BioEssays 36:11, pages 1062-1071.
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Overexpression of the pp32r1 (ANP32C) oncogene or its functional mutant pp32r1Y140H confers enhanced resistance to FTY720 (Finguimod)

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Overexpression of the pp32r1 (ANP32C) oncogene or its functional mutant pp32r1Y140H confers enhanced resistance to FTY720 (Finguimod)

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