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Research Paper

Doxorubicin and 5-fluorouracil induced accumulation and transcriptional activity of p53 are independent of the phosphorylation at serine 15 in MCF-7 breast cancer cells

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Pages 1000-1012 | Received 06 Dec 2013, Accepted 05 May 2014, Published online: 06 May 2014

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Mohammed M. Alvi, Rachel E. Nicoletto, Bayan A. Eshmawi, Hyun (Kate) Kim, Christopher R. Cammarata & Clyde M. Ofner$suffix/text()$suffix/text(). (2020) Intracellular trafficking and cytotoxicity of a gelatine–doxorubicin conjugate in two breast cancer cell lines. Journal of Drug Targeting 28:5, pages 487-499.
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Liang Zhang, Weiping Yang, Xiao Zhu & Changyuan Wei. (2016) p53 inhibits the expression of p125 and the methylation of POLD1 gene promoter by downregulating the Sp1-induced DNMT1 activities in breast cancer. OncoTargets and Therapy 9, pages 1351-1360.
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Ahmed M. Elshazly, Melanie M. Sinanian, Victoria Neely, Eesha Chakraborty, Muruj A. Alshehri, Michael K. McGrath, Hisashi Harada, Patricia V. Schoenlein & David A. Gewirtz. (2023) BRD4 Inhibition as a Strategy to Prolong the Response to Standard of Care in Estrogen Receptor-Positive Breast Cancer. Cancers 15:16, pages 4066.
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G Radha, S Raghunandhakumar & S Balakumar. (2023) Dual therapeutic 5-fluorouracil and hesperidin loaded chitosan nanocarrier system: Understanding its synergism on anti-cancer activity. Journal of Drug Delivery Science and Technology 80, pages 104184.
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Mohamed A. El-Desouky, Abdelgawad A. Fahmi, Ibrahim Y. Abdelkader & Karima M. Nasraldin. (2020) Anticancer Effect of Amygdalin (Vitamin B-17) on Hepatocellular Carcinoma Cell Line (HepG2) in the Presence and Absence of Zinc. Anti-Cancer Agents in Medicinal Chemistry 20:4, pages 486-494.
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Maiyon Park, Danielle Upton, Melodie Blackmon, Valerie Dixon, Scott Craver, Dawn Neal & Derek Perkins. (2018) Anacardic acid inhibits pancreatic cancer cell growth, and potentiates chemotherapeutic effect by Chmp1A - ATM - p53 signaling pathway. BMC Complementary and Alternative Medicine 18:1.
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David Moulder, Diana Hatoum, Enoch Tay, Yiguang Lin & Eileen McGowan. (2018) The Roles of p53 in Mitochondrial Dynamics and Cancer Metabolism: The Pendulum between Survival and Death in Breast Cancer?. Cancers 10:6, pages 189.
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Xiao-Ling Ma, Xiao-Cui Li, Fu-Ju Tian, Si-Ming Zhang, Xiao-Rui Liu, Yan Zhang, Jian-Xia Fan & Yi Lin. (2017) Effect of the p53–tristetraprolin–stathmin-1 pathway on trophoblasts at maternal–fetal interface. PLOS ONE 12:6, pages e0179852.
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Diana Hatoum, Daniel Yagoub, Alireza Ahadi, Najah T. Nassif & Eileen M. McGowan. (2017) Annexin/S100A Protein Family Regulation through p14ARF-p53 Activation: A Role in Cell Survival and Predicting Treatment Outcomes in Breast Cancer. PLOS ONE 12:1, pages e0169925.
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Chih-Yang Huang, Wei-Wen Kuo, Jeng-Fan Lo, Tsung-Jung Ho, Pei-ying Pai, Shu-Fen Chiang, Pei-Yu Chen, Fu-Jen Tsai, Chang-Hai Tsai & Chih-Yang Huang. (2016) Doxorubicin attenuates CHIP-guarded HSF1 nuclear translocation and protein stability to trigger IGF-IIR-dependent cardiomyocyte death. Cell Death & Disease 7:11, pages e2455-e2455.
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