Advanced search
Publication Cover
Cancer Biology & Therapy Volume 15, 2014 - Issue 10
Submit an article Journal homepage
975
Views
21
CrossRef citations to date
0
Altmetric
Research Paper

A novel small-molecule compound diaporine A inhibits non-small cell lung cancer growth by regulating miR-99a/mTOR signaling

Yuxian Song The State Key Laboratory of Pharmaceutical Biotechnology; Division of Immunology; Medical School; Nanjing University; Nanjing, PR China
,
Huan Dou The State Key Laboratory of Pharmaceutical Biotechnology; Division of Immunology; Medical School; Nanjing University; Nanjing, PR China
,
Ping Wang The State Key Laboratory of Pharmaceutical Biotechnology; Division of Immunology; Medical School; Nanjing University; Nanjing, PR China
,
Shuli Zhao Central Laboratory of Nanjing First Hospital; Nanjing Medical University; Nanjing, PR China
,
Tingting Wang The State Key Laboratory of Pharmaceutical Biotechnology; Division of Immunology; Medical School; Nanjing University; Nanjing, PR China
,
Wei Gong The State Key Laboratory of Pharmaceutical Biotechnology; Division of Immunology; Medical School; Nanjing University; Nanjing, PR China
,
Junli Zhao Nanjing Xiaozhuang College; Nanjing, PR China
,
Erguang Li The State Key Laboratory of Pharmaceutical Biotechnology; Division of Immunology; Medical School; Nanjing University; Nanjing, PR China
,
Renxiang Tan Institute of Functional Biomolecules; State Key Laboratory of Pharmaceutical Biotechnology; School of Lifesciences; Nanjing University; Nanjing, PR China
&
Yayi Hou The State Key Laboratory of Pharmaceutical Biotechnology; Division of Immunology; Medical School; Nanjing University; Nanjing, PR China; Jiangsu Key Laboratory of Molecular Medicine; Nanjing, PR ChinaCorrespondence[email protected]
 show all
Pages 1423-1430 | Received 15 May 2014, Accepted 13 Jul 2014, Published online: 21 Jul 2014

Citations (21)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (2)

Jiali Zhao, Fengli Chen, Quan Zhou, Wei Pan, Xinhong Wang, Jin Xu, Li Ni & Huilin Yang. (2016) Aberrant expression of microRNA-99a and its target gene mTOR associated with malignant progression and poor prognosis in patients with osteosarcoma. OncoTargets and Therapy 9, pages 1589-1597.
Read now
Xiukun Lin, Ammad Ahmad Farooqi & Muhammad Ismail. (2015) Recent progress in fungus-derived bioactive agents for targeting of signaling machinery in cancer cells. Drug Design, Development and Therapy 9, pages 1797-1804.
Read now

Articles from other publishers (19)

Pamela Vrabl, Bianka Siewert, Jacqueline Winkler, Harald Schöbel, Christoph W. Schinagl, Ludwig Knabl, Dorothea Orth-Höller, Johannes Fiala, Michael S. Meijer, Sylvestre Bonnet & Wolfgang Burgstaller. (2022) Xanthoepocin, a photolabile antibiotic of Penicillium ochrochloron CBS 123823 with high activity against multiresistant gram-positive bacteria. Microbial Cell Factories 21:1.
Crossref
Tamires Cunha Almeida, Isadora Oliveira Ansaloni Pereira, Edymara Dos Anjos Oliveira, Daniel Vitor de Souza, Daniel Araki Ribeiro & Glenda Nicioli da Silva. (2022) Modulation of non-coding RNAs by natural compounds as a potential therapeutical approach in oral cancer: A comprehensive review. Pathology - Research and Practice 239, pages 154166.
Crossref
Shiliu Tian, Rui Su, Ke Wu, Xuhan Zhou, Jaydutt V. Vadgama & Yong Wu. (2022) Diaporine Potentiates the Anticancer Effects of Oxaliplatin and Doxorubicin on Liver Cancer Cells. Journal of Personalized Medicine 12:8, pages 1318.
Crossref
Yue Jiang, Xiangpan Li, Yu Yang, Jiajun Luo, Xunshan Ren, Jingwen Yuan & Qiang Tong. (2022) LncRNA HOXC-AS1 Sponges miR-99a-3p and Upregulates MMP8, Ultimately Promoting Gastric Cancer. Cancers 14:14, pages 3534.
Crossref
Rebecca Raue, Ann-Christin Frank, Shahzad Nawaz Syed & Bernhard Brüne. (2021) Therapeutic Targeting of MicroRNAs in the Tumor Microenvironment. International Journal of Molecular Sciences 22:4, pages 2210.
Crossref
H.C. Yashavantha Rao, D. Sruthi, Subban Kamalraj, Ramalingam Parthasarathy & Chelliah Jayabaskaran. 2021. Volatiles and Metabolites of Microbes. Volatiles and Metabolites of Microbes 305 323 .
Natalia Gablo, Karolina Trachtova, Vladimir Prochazka, Jan Hlavsa, Tomas Grolich, Igor Kiss, Josef Srovnal, Alona Rehulkova, Martin Lovecek, Pavel Skalicky, Ioana Berindan-Neagoe, Zdenek Kala & Ondrej Slaby. (2020) Identification and Validation of Circulating Micrornas as Prognostic Biomarkers in Pancreatic Ductal Adenocarcinoma Patients Undergoing Surgical Resection. Journal of Clinical Medicine 9:8, pages 2440.
Crossref
Shunbin Shi, Guiping Yu, Bin Huang, Yedong Mi, Yan Kang & Julia Pia Simon. (2020) PPARG Could Work as a Valid Therapeutic Strategy for the Treatment of Lung Squamous Cell Carcinoma. PPAR Research 2020, pages 1-9.
Crossref
Moumita Kundu, Subhayan Das, Dibakar Dhara & Mahitosh Mandal. (2019) Prospect of natural products in glioma: A novel avenue in glioma management. Phytotherapy Research 33:10, pages 2571-2584.
Crossref
Mohammadhassan Gholami-Shabani, Masoomeh Shams-Ghahfarokhi & Mehdi Razzaghi-Abyaneh. 2019. Recent Advancement in White Biotechnology Through Fungi. Recent Advancement in White Biotechnology Through Fungi 195 228 .
Yin Tang, Lan Zhang, Tianchi Tu, Yijia Li, Dana Murray, Qisheng Tu & Jake Jinkun Chen. (2018) MicroRNA‐99a is a novel regulator of KDM6B‐mediated osteogenic differentiation of BMSCs. Journal of Cellular and Molecular Medicine 22:4, pages 2162-2176.
Crossref
Huimin Yue, Yarong Zhao, Haining Wang, Feiya Ma, Fei Liu, Sunan Shen, Yayi Hou & Huan Dou. (2017) Anti-fibrosis effect for Hirsutella sinensis mycelium based on inhibition of mTOR p70S6K phosphorylation . Innate Immunity 23:7, pages 615-624.
Crossref
Qian Lin, Leina Ma, Zhantao Liu, Zhihong Yang, Jin Wang, Jia Liu & Guohui Jiang. (2016) Targeting microRNAs: a new action mechanism of natural compounds. Oncotarget 8:9, pages 15961-15970.
Crossref
Glenn W. Vicary & Jesse Roman. (2016) Targeting the Mammalian Target of Rapamycin in Lung Cancer. The American Journal of the Medical Sciences 352:5, pages 507-516.
Crossref
Xiujing Feng, Wen Yu, Feifei Zhou, Jiajia Chen & Pingping Shen. (2016) A novel small molecule compound diaporine inhibits breast cancer cell proliferation via promoting ROS generation. Biomedicine & Pharmacotherapy 83, pages 1038-1047.
Crossref
Bin Lu, Yuchen Sheng, Jiaqi Zhang, Zhiyong Zheng & Lili Ji. (2016) The altered microRNA profile in andrographolide-induced inhibition of hepatoma tumor growth. Gene 588:2, pages 124-133.
Crossref
Ji Hoon Jung, Moon Joon Kim, Hyemin Lee, Jihyun Lee, Jaekwang Kim, Hyun Joo Lee, Eun Ah Shin, Yoon Hyeon Kim, Bonglee Kim, Bum Sang Shim & Sung-Hoon Kim. (2016) Farnesiferol c induces apoptosis via regulation of L11 and c-Myc with combinational potential with anticancer drugs in non-small-cell lung cancers. Scientific Reports 6:1.
Crossref
MEI SUN, SHUNMING HONG, WENHAN LI, PENGFEI WANG, JINQIANG YOU, XUEBIN ZHANG, FAN TANG, PING WANG & CHUNZHI ZHANG. (2016) miR-99a regulates ROS-mediated invasion and migration of lung adenocarcinoma cells by targeting NOX4. Oncology Reports 35:5, pages 2755-2766.
Crossref
Scott M. Riester, Diren Arsoy, Emily T. Camilleri, Amel Dudakovic, Christopher R. Paradise, Jared M. Evans, Jorge Torres-Mora, Marco Rizzo, Peter Kloen, Marianna Kruithof-de Julio, Andre J. van Wijnen & Sanjeev Kakar. (2015) RNA sequencing reveals a depletion of collagen targeting microRNAs in Dupuytren’s disease. BMC Medical Genomics 8:1.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.