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Research Paper

Role of p53/p21Waf1/Cip1 in the regulation of polyamine analogue-induced growth inhibition and cell death in human breast cancer cells

Pages 1006-1013 | Published online: 23 Jun 2005

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C. O. Soares, M. Boiani, L. J. Marnett & E. J. H. Bechara. (2013) Cytotoxicity of 1,4-diamino-2-butanone, a putrescine analogue, to RKO cells: mechanism and redox imbalance. Free Radical Research 47:9, pages 672-682.
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Shaymaa M.M. Yahya, Abdou O. Abdelhamid, Mervat M. Abd-Elhalim, Ghada H. Elsayed & Emad F. Eskander. (2017) The effect of newly synthesized progesterone derivatives on apoptotic and angiogenic pathway in MCF-7 breast cancer cells. Steroids 126, pages 15-23.
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Gamal A. Elmegeed, Shaymaa M.M. Yahya, Mervat M. Abd-Elhalim, Mervat S. Mohamed, Rafat M. Mohareb & Ghada H. Elsayed. (2016) Evaluation of heterocyclic steroids and curcumin derivatives as anti-breast cancer agents: Studying the effect on apoptosis in MCF-7 breast cancer cells. Steroids 115, pages 80-89.
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Yu Zhu, Jing Li, Shrey Kanvinde, Zhiyi Lin, Stuart Hazeldine, Rakesh K. Singh & David Oupický. (2014) Self-Immolative Polycations as Gene Delivery Vectors and Prodrugs Targeting Polyamine Metabolism in Cancer. Molecular Pharmaceutics 12:2, pages 332-341.
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Qingsong Zhu, Lihua Jin, Robert A. Casero, Nancy E. Davidson & Yi Huang. (2012) Role of ornithine decarboxylase in regulation of estrogen receptor alpha expression and growth in human breast cancer cells. Breast Cancer Research and Treatment 136:1, pages 57-66.
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Yanmei Dong, Yu Zhu, Jing Li, Qing-Hui Zhou, Chao Wu & David Oupický. (2012) Synthesis of Bisethylnorspermine Lipid Prodrug as Gene Delivery Vector Targeting Polyamine Metabolism in Breast Cancer. Molecular Pharmaceutics 9:6, pages 1654-1664.
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Xuan Zhang, Ridhwi Mukerji, Abbas K Samadi & Mark S Cohen. (2011) Down-regulation of estrogen receptor-alpha and rearranged during transfection tyrosine kinase is associated with withaferin a-induced apoptosis in MCF-7 breast cancer cells. BMC Complementary and Alternative Medicine 11:1.
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Yi Huang, Laurence J. Marton & Patrick M. Woster. 2011. Polyamine Drug Discovery. Polyamine Drug Discovery 238 256 .
D.-I. Kim, S.-J. Lee, S.-B. Lee, K. Park, W.-J. Kim & S.-K. Moon. (2008) Requirement for Ras/Raf/ERK pathway in naringin-induced G1-cell-cycle arrest via p21WAF1 expression. Carcinogenesis 29:9, pages 1701-1709.
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Robert A. CaseroJrJr & Laurence J. Marton. (2007) Targeting polyamine metabolism and function in cancer and other hyperproliferative diseases. Nature Reviews Drug Discovery 6:5, pages 373-390.
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Yi Huang, Judith C. Keen, Allison Pledgie, Laurence J. Marton, Tao Zhu, Saraswati Sukumar, Ben Ho Park, Brian Blair, Keith Brenner, Robert A. CaseroJrJr & Nancy E. Davidson. (2006) Polyamine Analogues Down-regulate Estrogen Receptor α Expression in Human Breast Cancer Cells. Journal of Biological Chemistry 281:28, pages 19055-19063.
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