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Review

Cancer-selective therapy of the future: Apoptin and its mechanism of action

Pages 10-19 | Published online: 16 Jan 2006

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A. A. Rosenkranz, A. V. Ulasov, T. A. Slastnikova, Y. V. Khramtsov & A. S. Sobolev. (2014) Use of intracellular transport processes for targeted drug delivery into a specified cellular compartment. Biochemistry (Moscow) 79:9, pages 928-946.
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W A Pennant, S An, S-J Gwak, S Choi, D T Banh, A B L Nguyen, H Y Song, Y Ha & J-S Park. (2013) Local non-viral gene delivery of apoptin delays the onset of paresis in an experimental model of intramedullary spinal cord tumor. Spinal Cord 52:1, pages 3-8.
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Suna Zhou, Mingxin Zhang, Jia Zhang, Hui Shen, Ermek Tangsakar & Jiansheng Wang. (2011) Mechanisms of Apoptin-induced cell death. Medical Oncology 29:4, pages 2985-2991.
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Qing Zhu. (2012) Systemic delivery of lentivirus-mediated secretable TAT-apoptin eradicates hepatocellular carcinoma xenografts in nude mice. International Journal of Oncology.
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Henriëtte L. Lanz, Bogdan I. Florea, Mathieu H.M. Noteborn & Claude Backendorf. (2012) Development and application of an in vitro apoptin kinase assay. Analytical Biochemistry 421:1, pages 68-74.
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Rong Zeng, Linlan Zeng, Yan Chen, Fei Zhao, Rui Li, Lu Wen & Chun Zhang. (2011) Triptolide-induced apoptosis by inactivating nuclear factor-kappa B apoptotic pathway in multiple myeloma in vitro. Journal of Huazhong University of Science and Technology [Medical Sciences] 31:4, pages 446-451.
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Chunyan WangYujing Zhang. (2011) Apoptin Gene Transfer via Modified Wheat Histone H4 Facilitates Apoptosis of Human Ovarian Cancer Cells. Cancer Biotherapy and Radiopharmaceuticals 26:1, pages 121-126.
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Liu Yan, Meng Xiangwei, Li Xiao, Gao Peng, Li Chang, Tian Mingyao, Yang Encheng, Xu Xiaohong, Jia Peng, Kan Shifu, Wen Zhongmei & Jin Ningyi. (2010) Construction, expression and characterization of a dual cancer-specific fusion protein targeting carcinoembryonic antigen in intestinal carcinomas. Protein Expression and Purification 69:1, pages 120-125.
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Yongfei Pan, Liurong Fang, Huiying Fan, Rui Luo, Qian Zhao, Huanchun Chen & Shaobo Xiao. (2010) Antitumor effects of a recombinant pseudotype baculovirus expressing Apoptin in vitro and in vivo . International Journal of Cancer, pages NA-NA.
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Yu Zhou, Hong Chen, Xiao-Li Ma, Hai-Jun Xie, Cun-Lin Wang, Sheng-Hua Zhang, Xin Wang & Bing-Ren Huang. (2009) Fusion protein of adenovirus E4orf4 and human epidermal growth factor inhibits tumor cell growth. International Journal of Cancer 125:5, pages 1186-1192.
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Jun Sun, Ying Yan, Xiao-Ting Wang, Xiao-Wen Liu, Dong-Jun Peng, Min Wang, Jun Tian, Yi-Qiang Zong, Ying-Hui Zhang, Mathieu H.M. Noteborn & Shen Qu. (2009) PTD4-apoptin protein therapy inhibits tumor growth in vivo . International Journal of Cancer 124:12, pages 2973-2981.
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