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Klotho, the long sought-after elixir and a novel tumor suppressor?

Pages 20-21 | Published online: 16 Jan 2006

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (1)

Lingeng Lu, Dionyssios Katsaros, Andrew Wiley, Irene A. Rigault de la Longrais, Manuela Puopolo & Herbert Yu. (2008) Klotho Expression in Epithelial Ovarian Cancer and its Association with Insulin-Like Growth Factors and Disease Progression. Cancer Investigation 26:2, pages 185-192.
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Articles from other publishers (7)

Ella Zeldich, Ci-Di Chen, Emma Boden, Bryce Howat, Jason S. Nasse, Dean Zeldich, Anthony G. Lambert, Andrea Yuste, Jonathan D. Cherry, Rebecca M. Mathias, Qicheng Ma, Nelson C. Lau, Ann C. McKee, Theo Hatzipetros & Carmela R. Abraham. (2019) Klotho Is Neuroprotective in the Superoxide Dismutase (SOD1G93A) Mouse Model of ALS. Journal of Molecular Neuroscience 69:2, pages 264-285.
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Rik Mencke, Hannes Olauson & Jan-Luuk Hillebrands. (2017) Effects of Klotho on fibrosis and cancer: A renal focus on mechanisms and therapeutic strategies. Advanced Drug Delivery Reviews 121, pages 85-100.
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Yue Guo, Xiao-Dong Zhuang, Wen-Biao Xian, Ling-Ling Wu, Ze-Na Huang, Xun Hu, Xiang-Song Zhang, Ling Chen & Xin-Xue Liao. (2017) Serum Klotho, vitamin D, and homocysteine in combination predict the outcomes of Chinese patients with multiple system atrophy. CNS Neuroscience & Therapeutics 23:8, pages 657-666.
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Michael Bordonaro & Darina L. Lazarova. (2014) Hypothesis: cell signalling influences age‐related risk of colorectal cancer. Journal of Cellular and Molecular Medicine 19:1, pages 74-81.
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Ella Zeldich, Ci-Di Chen, Teresa A. Colvin, Erin A. Bove-Fenderson, Jennifer Liang, Tracey B. Tucker Zhou, David A. Harris & Carmela R. Abraham. (2014) The Neuroprotective Effect of Klotho is Mediated via Regulation of Members of the Redox System. Journal of Biological Chemistry 289:35, pages 24700-24715.
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Beate Rinner, Andreas Weinhaeusel, Birgit Lohberger, Elke Verena Froehlich, Walter Pulverer, Carina Fischer, Katharina Meditz, Susanne Scheipl, Slave Trajanoski, Christian Guelly, Andreas Leithner & Bernadette Liegl. (2013) Chordoma Characterization of Significant Changes of the DNA Methylation Pattern. PLoS ONE 8:3, pages e56609.
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Jie Pan, Jing Zhong, Li Hong Gan, Shu Jie Chen, Hong Chuan Jin, Xian Wang & Liang Jing Wang. (2011) Klotho, an anti-senescence related gene, is frequently inactivated through promoter hypermethylation in colorectal cancer. Tumor Biology 32:4, pages 729-735.
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