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Yan-Yang Wang, Yin-Xue Yang, Hong Zhe, Zhi-Xu He & Shu-Feng Zhou. (2014) Bardoxolone methyl (CDDO-Me) as a therapeutic agent: an update on its pharmacokinetic and pharmacodynamic properties. Drug Design, Development and Therapy 8, pages 2075-2088.
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Donna D. Zhang & Eli Chapman. (2020) The role of natural products in revealing NRF2 function. Natural Product Reports 37:6, pages 797-826.
Crossref
Crossref
Namrata Chaudhari & Palaniyandi Ravanan. (2018) Bardoxolone methyl induces neuritogenesis in Neuro2a cells. Pharmacological Reports 70:4, pages 730-736.
Crossref
Crossref
Ping Gong, Kun Li, Ying Li, Dan Liu, Linxiang Zhao & Yongkui Jing. (2018) HDAC and Ku70 axis- an effective target for apoptosis induction by a new 2-cyano-3-oxo-1,9-dien glycyrrhetinic acid analogue. Cell Death & Disease 9:6.
Crossref
Crossref
You-Take Oh, Liang Deng, Jiusheng Deng & Shi-Yong Sun. (2017) The proteasome deubiquitinase inhibitor b-AP15 enhances DR5 activation-induced apoptosis through stabilizing DR5. Scientific Reports 7:1.
Crossref
Crossref
Yonas Getachew, Frank A. Cusimano, Purva Gopal, Scott A. Reisman & Jerry W. Shay. (2016) The Synthetic Triterpenoid RTA 405 (CDDO-EA) Halts Progression of Liver Fibrosis and Reduces Hepatocellular Carcinoma Size Resulting in Increased Survival in an Experimental Model of Chronic Liver Injury. Toxicological Sciences 149:1, pages 111-120.
Crossref
Crossref
Weilong Yao, Ping Yue, Fadlo R. Khuri & Shi-Yong Sun. (2015) The BET bromodomain inhibitor, JQ1, facilitates c-FLIP degradation and enhances TRAIL-induced apoptosis independent of BRD4 and c-Myc inhibition. Oncotarget 6:33, pages 34669-34679.
Crossref
Crossref
Soo Ah Jeong, In Young Kim, A Reum Lee, Mi Jin Yoon, Hyeseong Cho, Jong-Soo Lee & Kyeong Sook Choi. (2015) Ca2+ influx-mediated dilation of the endoplasmic reticulum and c-FLIPL downregulation trigger CDDO-Me-induced apoptosis in breast cancer cells. Oncotarget 6:25, pages 21173-21192.
Crossref
Crossref
Brandon L. Probst, Isaac Trevino, Lyndsey McCauley, Ron Bumeister, Irina Dulubova, W. Christian Wigley & Deborah A. Ferguson. (2015) RTA 408, A Novel Synthetic Triterpenoid with Broad Anticancer and Anti-Inflammatory Activity. PLOS ONE 10:4, pages e0122942.
Crossref
Crossref
Vitali Alexeev, Elizabeth Lash, April Aguillard, Laura Corsini, Avi Bitterman, Keith Ward, Adam P. Dicker, Alban Linnenbach & Ulrich Rodeck. (2014) Radiation Protection of the Gastrointestinal Tract and Growth Inhibition of Prostate Cancer Xenografts by a Single Compound. Molecular Cancer Therapeutics 13:12, pages 2968-2977.
Crossref
Crossref
Muthu K. Shanmugam, Xiaoyun Dai, Alan Prem Kumar, Benny K.H. Tan, Gautam Sethi & Anupam Bishayee. (2014) Oleanolic acid and its synthetic derivatives for the prevention and therapy of cancer: Preclinical and clinical evidence. Cancer Letters 346:2, pages 206-216.
Crossref
Crossref
Yan-Yang Wang, Hong Zhe & Ren Zhao. (2014) Preclinical evidences toward the use of triterpenoid CDDO-Me for solid cancer prevention and treatment. Molecular Cancer 13:1, pages 30.
Crossref
Crossref
Xiaojing Li, Yuetong Wang, Yuan Gao, Lei Li, Xin Guo, Dan Liu, Yongkui Jing & Linxiang Zhao. (2014) Synthesis of methyl 2-cyano-3,12-dioxo-18β-olean-1,9(11)-dien-30-oate analogues to determine the active groups for inhibiting cell growth and inducing apoptosis in leukemia cells. Organic & Biomolecular Chemistry 12:34, pages 6706.
Crossref
Crossref
Li Feng, Xiaoyu Liu, Weiliang Zhu, Fujiang Guo, YingchunWu, Rui Wang, Kaixian Chen, Cheng Huang & Yiming Li. (2013) Inhibition of Human Neutrophil Elastase by Pentacyclic Triterpenes. PLoS ONE 8:12, pages e82794.
Crossref
Crossref
Sarah Shirley & Olivier Micheau. (2013) Targeting c-FLIP in cancer. Cancer Letters 332:2, pages 141-150.
Crossref
Crossref
Christian L. Barrett, Richard B. Schwab, HyunChul Jung, Brian Crain, Daniel J. Goff, Catriona H. M. Jamieson, Patricia A. Thistlethwaite, Olivier Harismendy, Dennis A. Carson & Kelly A. Frazer. (2013) Transcriptome Sequencing of Tumor Subpopulations Reveals a Spectrum of Therapeutic Options for Squamous Cell Lung Cancer. PLoS ONE 8:3, pages e58714.
Crossref
Crossref
Sahdeo Prasad, Subash C. Gupta, Bokyung Sung & Bharat B. Aggarwal. 2013. Cancer Chemoprevention and Treatment by Diet Therapy. Cancer Chemoprevention and Treatment by Diet Therapy
233
267
.
Natalia Aptsiauri, Teresa Cabrera, Angel Garcia-Lora, Francisco Ruiz-Cabello & Federico Garrido. 2013. The Tumor Immunoenvironment. The Tumor Immunoenvironment
253
286
.
Natalia Aptsiauri, Angel Miguel Garcia-Lora & Teresa CabreraNatalia Aptsiauri, Angel Miguel Garcia-Lora & Teresa Cabrera. 2013. MHC Class I Antigens In Malignant Cells. MHC Class I Antigens In Malignant Cells
1
11
.
Karen T. Liby & Michael B. Sporn. (2012) Synthetic Oleanane Triterpenoids: Multifunctional Drugs with a Broad Range of Applications for Prevention and Treatment of Chronic Disease. Pharmacological Reviews 64:4, pages 972-1003.
Crossref
Crossref
Muthu K. Shanmugam, An H. Nguyen, Alan P. Kumar, Benny K.H. Tan & Gautam Sethi. (2012) Targeted inhibition of tumor proliferation, survival, and metastasis by pentacyclic triterpenoids: Potential role in prevention and therapy of cancer. Cancer Letters 320:2, pages 158-170.
Crossref
Crossref
C. I. Delebinski, S. Jaeger, K. Kemnitz‐Hassanin, G. Henze, H. N. Lode & G. J. Seifert. (2012)
A new development of triterpene acid‐containing extracts from
Viscum album
L. displays synergistic induction of apoptosis in acute lymphoblastic leukaemia
. Cell Proliferation 45:2, pages 176-187.
Crossref
Crossref
Ivan Scudiero, Tiziana Zotti, Angela Ferravante, Mariangela Vessichelli, Carla Reale, Maria C. Masone, Antonio Leonardi, Pasquale Vito & Romania Stilo. (2012) Tumor Necrosis Factor (TNF) Receptor-associated Factor 7 Is Required for TNFα-induced Jun NH2-terminal Kinase Activation and Promotes Cell Death by Regulating Polyubiquitination and Lysosomal Degradation of c-FLIP Protein. Journal of Biological Chemistry 287:8, pages 6053-6061.
Crossref
Crossref
Peter Hersey & Xu Dong Zhang. 2012. Targeted Therapeutics in Melanoma. Targeted Therapeutics in Melanoma
125
153
.
Palaniyandi Ravanan, Renata Sano, Priti Talwar, Satoshi Ogasawara, Shu-ichi Matsuzawa, Michael Cuddy, Sanjay K. Singh, G.S.R. Subba Rao, Paturu Kondaiah & John C. Reed. (2011) Synthetic Triterpenoid Cyano Enone of Methyl Boswellate Activates Intrinsic, Extrinsic, and Endoplasmic Reticulum Stress Cell Death Pathways in Tumor Cell Lines. Molecular Cancer Therapeutics 10:9, pages 1635-1643.
Crossref
Crossref
Yingqi Hua, Zhiyu Zhang, Jianxin Li, Quan Li, Shuo Hu, Jian Li, Mengxiong Sun & Zhengdong Cai. (2009) Oleanolic acid derivative Dex-OA has potent anti-tumor and anti-metastatic activity on osteosarcoma cells in vitro and in vivo. Investigational New Drugs 29:2, pages 258-265.
Crossref
Crossref
Ciric To, Brian H. Shilton & Gianni M. Di Guglielmo. (2010) Synthetic Triterpenoids Target the Arp2/3 Complex and Inhibit Branched Actin Polymerization. Journal of Biological Chemistry 285:36, pages 27944-27957.
Crossref
Crossref
Sujin Lee, Hideo Yagita, Thomas J. Sayers & Esteban Celis. (2010) Optimized combination therapy using bortezomib, TRAIL and TLR agonists in established breast tumors. Cancer Immunology, Immunotherapy 59:7, pages 1073-1081.
Crossref
Crossref
Ugur Eskiocak, Sang Bum Kim, Andres I. Roig, Erin Kitten, Kimberly Batten, Crystal Cornelius, Ying S. Zou, Woodring E. Wright & Jerry W. Shay. (2010) CDDO-Me Protects against Space Radiation-Induced Transformation of Human Colon Epithelial Cells. Radiation Research 174:1, pages 27.
Crossref
Crossref
J.H. Stegehuis, L.H.A.M. de Wilt, E.G.E. de Vries, H.J. Groen, S. de Jong & F.A.E. Kruyt. (2010) TRAIL receptor targeting therapies for non-small cell lung cancer: Current status and perspectives. Drug Resistance Updates 13:1-2, pages 2-15.
Crossref
Crossref
M R Abedini, E J Muller, R Bergeron, D A Gray & B K Tsang. (2009) Akt promotes chemoresistance in human ovarian cancer cells by modulating cisplatin-induced, p53-dependent ubiquitination of FLICE-like inhibitory protein. Oncogene 29:1, pages 11-25.
Crossref
Crossref
Alessia Petronelli, Gaetano Pannitteri & Ugo Testa. (2009) Triterpenoids as new promising anticancer drugs. Anti-Cancer Drugs 20:10, pages 880-892.
Crossref
Crossref
Peter Hersey & Xu Dong Zhang. (2009) Treatment combinations targeting apoptosis to improve immunotherapy of melanoma. Cancer Immunology, Immunotherapy 58:11, pages 1749-1759.
Crossref
Crossref
Alessia Petronelli, Ernestina Saulle, Luca Pasquini, Eleonora Petrucci, Gualtiero Mariani, Mauro Biffoni, Gianluigi Ferretti, Giovanni Scambia, Pierluigi Benedetti-Panici, Stefano Greggi, Francesco Cognetti, Matteo Antonio Russo, Michael Sporn & Ugo Testa. (2009) High sensitivity of ovarian cancer cells to the synthetic triterpenoid CDDO-Imidazolide. Cancer Letters 282:2, pages 214-228.
Crossref
Crossref
Daniel Nowak, Daphne Stewart & H. Phillip Koeffler. (2009) Differentiation therapy of leukemia: 3 decades of development. Blood 113:16, pages 3655-3665.
Crossref
Crossref
Yidan Lin, Xiangguo Liu, Ping Yue, Doris M. Benbrook, K. Darrell Berlin, Fadlo R. Khuri & Shi-Yong Sun. (2008) Involvement of c-FLIP and survivin down-regulation in flexible heteroarotinoid-induced apoptosis and enhancement of TRAIL-initiated apoptosis in lung cancer cells. Molecular Cancer Therapeutics 7:11, pages 3556-3565.
Crossref
Crossref
Mohammad R. Abedini, Emilie J. Muller, Jan Brun, Richard Bergeron, Douglas A. Gray & Benjamin K. Tsang. (2008) Cisplatin Induces p53-Dependent FLICE-Like Inhibitory Protein Ubiquitination in Ovarian Cancer Cells. Cancer Research 68:12, pages 4511-4517.
Crossref
Crossref
Gui-jin HE, Dan-dan SUN, Da-wei JI, Dong-ming SUI, Fa-qiang YU, Qin-yi GAO, Xian-wei DAI, Hong GAO, Tao JIANG & Chao-liu DAI. (2008) Induction of biliary cholangiocarcinoma cell apoptosis by 103Pd cholangial radioactive stent γ-rays. Chinese Medical Journal 121:11, pages 1020-1024.
Crossref
Crossref
Marc L. Hyer, Ranxin Shi, Maryla Krajewska, Colin Meyer, Irina V. Lebedeva, Paul B. Fisher & John C. Reed. (2008) Apoptotic Activity and Mechanism of 2-Cyano-3,12-Dioxoolean-1,9-Dien-28-Oic-Acid and Related Synthetic Triterpenoids in Prostate Cancer. Cancer Research 68:8, pages 2927-2933.
Crossref
Crossref