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Research Paper

Hypoxia induced overexpression of PrPC in gastric cancer cell lines

Pages 769-774 | Published online: 30 May 2007

Keep up to date with the latest research on this topic with citation updates for this article.

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Han Sung Hwang, Seung Hwa Park, Yong Won Park, Han Sung Kwon & In Sook Sohn. (2010) Expression of cellular prion protein in the placentas of women with normal and preeclamptic pregnancies. Acta Obstetricia et Gynecologica Scandinavica 89:9, pages 1155-1161.
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Houman Khosravani, Yunfeng Zhang & Gerald W. Zamponi. (2008) Cellular prion protein null mice display normal AMPA receptor mediated long term depression. Prion 2:2, pages 48-50.
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Articles from other publishers (28)

JingFeng Li, SaSa Li, ShuPei Yu, Jie Yang, JingRu Ke, Huan Li, Heng Chen, MingJian Lu, Man-Sun Sy, ZhenXing Gao & Chaoyang Li. (2023) Persistent ER stress causes GPI anchor deficit to convert a GPI-anchored prion protein into pro-PrP via the ATF6–miR449c-5p–PIGV axis. Journal of Biological Chemistry 299:8, pages 104982.
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Izabella Grimaldi, Felipe Saceanu Leser, José Marcos Janeiro, Bárbara Gomes da Rosa, Ana Clara Campanelli, Luciana Romão & Flavia Regina Souza Lima. (2022) The multiple functions of PrPC in physiological, cancer, and neurodegenerative contexts. Journal of Molecular Medicine 100:10, pages 1405-1425.
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Doris Loh & Russel J. Reiter. (2022) Melatonin: Regulation of Prion Protein Phase Separation in Cancer Multidrug Resistance. Molecules 27:3, pages 705.
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Sophie Mouillet-Richard, Alexandre Ghazi & Pierre Laurent-Puig. (2021) The Cellular Prion Protein and the Hallmarks of Cancer. Cancers 13:19, pages 5032.
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Alexey P. Galkin & Evgeniy I. Sysoev. (2021) Stress Response Is the Main Trigger of Sporadic Amyloidoses. International Journal of Molecular Sciences 22:8, pages 4092.
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Berta Puig, Denise Yang, Santra Brenna, Hermann Clemens Altmeppen & Tim Magnus. (2020) Show Me Your Friends and I Tell You Who You Are: The Many Facets of Prion Protein in Stroke. Cells 9:7, pages 1609.
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Sabino Russi, Henu Kumar Verma, Simona Laurino, Pellegrino Mazzone, Giovanni Storto, Anna Nardelli, Pietro Zoppoli, Giovanni Calice, Francesco La Rocca, Alessandro Sgambato, Valeria Lucci, Geppino Falco & Vitalba Ruggieri. (2019) Adapting and Surviving: Intra and Extra-Cellular Remodeling in Drug-Resistant Gastric Cancer Cells. International Journal of Molecular Sciences 20:15, pages 3736.
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Lidia De Riccardis, Francesca Rizzo, Emanuela Urso, Valeria Garzarelli, Vincenza Intini, Marco Greco, Maria Chiara Maffia, Antonio Danieli & Michele Maffia. (2019) Physiological role of Prion Protein in Copper homeostasis and angiogenic mechanisms of endothelial cells. The EuroBiotech Journal 3:2, pages 57-70.
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Hidenori KANDA, Takeharu KANEDA, Yuta NAGAI, Norimoto URAKAWA & Kazumasa SHIMIZU. (2018) Aerobic metabolism on muscle contraction in porcine gastric smooth muscle. Journal of Veterinary Medical Science 80:5, pages 846-850.
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Guanhong Luo, Weijie Wang, Qiong Wu, Yuanyuan Lu, Tao Su, Nan Gu, Kai Li, Jingbo Wang, Rui Du, Xiaodi Zhao, Xiaohua Li, Rui Fan, Hongbo Zhang, Yongzhan Nie, Xinmin Zhou, Yongquan Shi, Jie Liang, Xin Wang & Daiming Fan. (2017) MGr1-Antigen/37 kDa laminin receptor precursor promotes cellular prion protein induced multi-drug-resistance of gastric cancer. Oncotarget 8:42, pages 71630-71641.
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Jiang Wang, Hongbo You, Jun Qi, Caihong Yang, Ye Ren & Hao Cheng. (2017) Autocrine and paracrine STIP1 signaling promote osteolytic bone metastasis in renal cell carcinoma. Oncotarget 8:10, pages 17012-17026.
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Marc-André Déry & Andréa C. LeBlanc. (2017) Luman contributes to brefeldin A-induced prion protein gene expression by interacting with the ERSE26 element. Scientific Reports 7:1.
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Susan F. Godsave, Peter J. Peters & Holger Wille. (2015) Subcellular distribution of the prion protein in sickness and in health. Virus Research 207, pages 136-145.
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Jin-Young Park, Jae-Kyo Jeong, Ju-Hee Lee, Ji-Hong Moon, Sung-Wook Kim, You-Jin Lee & Sang-Youel Park. (2015) Induction of cellular prion protein (PrPc) under hypoxia inhibits apoptosis caused by TRAIL treatment. Oncotarget 6:7, pages 5342-5353.
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Emanuela Urso & Michele Maffia. (2015) Behind the Link between Copper and Angiogenesis: Established Mechanisms and an Overview on the Role of Vascular Copper Transport Systems. Journal of Vascular Research 52:3, pages 172-196.
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Séverine Martin-Lannerée, Théo Z. Hirsch, Julia Hernandez-Rapp, Sophie Halliez, Jean-Luc Vilotte, Jean-Marie Launay & Sophie Mouillet-Richard. (2014) PrP C from stem cells to cancer . Frontiers in Cell and Developmental Biology 2.
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Hui Zhang, Li Sun, Xiao Xiao, Rougang Xie, Changhao Liu, Yafang Wang, Yanling Wei, Hongbo Zhang & Lili Liu. (2014) Krüppel‐like factor 8 contributes to hypoxia‐induced MDR in gastric cancer cells . Cancer Science 105:9, pages 1109-1115.
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Marc-André Déry, Julie Jodoin, Josie Ursini-Siegel, Olga Aleynikova, Cristiano Ferrario, Saima Hassan, Mark Basik & Andréa C LeBlanc. (2013) Endoplasmic reticulum stress induces PRNP prion protein gene expression in breast cancer. Breast Cancer Research 15:2.
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Nadia AlfaidySylvain ChauvetSandrine Donadio-AndreiAude SalomonYasmina SaoudiPierre RichaudCatherine Aude-GarciaPascale HoffmannAnnie AndrieuxJean-Marc MoulisJean-Jacques FeigeMohamed Benharouga. (2013) Prion Protein Expression and Functional Importance in Developmental Angiogenesis: Role in Oxidative Stress and Copper Homeostasis. Antioxidants & Redox Signaling 18:4, pages 400-411.
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Jae-Kyo Jeong, Jae-Suk Seo, Myung-Hee Moon, You-Jin Lee, Jae-Won Seol & Sang-Youel Park. (2012) Hypoxia-inducible factor-1 alpha regulates prion protein expression to protect against neuron cell damage. Neurobiology of Aging 33:5, pages 1006.e1-1006.e10.
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Ji Heng WANG, Jing Ping DU, Shu Jun LI, Li Ping ZHAI, Xin Yan YANG, Zhi Hong WANG, Zi Tao WU & Ying HAN. (2012) Octarepeat peptides of prion are essential for multidrug resistance in gastric cancer cells. Journal of Digestive Diseases 13:3, pages 143-152.
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Qing-Quan Li, Yan-Ping Sun, Can-Ping Ruan, Xin-Yun Xu, Jun-Hui Ge, Jin He, Zu-De Xu, Qiang Wang & Wen-Chao Gao. (2011) Cellular prion protein promotes glucose uptake through the Fyn-HIF-2α-Glut1 pathway to support colorectal cancer cell survival. Cancer Science 102:2, pages 400-406.
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Dexin ZhangDaiming Fan. (2010) New insights into the mechanisms of gastric cancer multidrug resistance and future perspectives. Future Oncology 6:4, pages 527-537.
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Maryam Mehrpour & Patrice Codogno. (2010) Prion protein: From physiology to cancer biology. Cancer Letters 290:1, pages 1-23.
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Jae‐Suk Seo, Jae‐Won Seol, Myung‐Hee Moon, Jae‐Kyo Jeong, You‐Jin Lee & Sang‐Youel Park. (2010) Hypoxia protects neuronal cells from human prion protein fragment‐induced apoptosis. Journal of Neurochemistry 112:3, pages 715-722.
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Jie Liang, Jingbo Wang, Guanhong Luo, Yanglin Pan, Xin Wang, Changcun Guo, Dexin Zhang, Fang Yin, Xiaoyin Zhang, Jie Liu, Jianhong Wang, Xuegang Guo, Kaichun Wu & Daiming Fan. (2009) Function of PrP C (1-OPRD) in biological activities of gastric cancer cell lines . Journal of Cellular and Molecular Medicine 13:11-12, pages 4453-4464.
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Oriol Nicolas, Rosalina Gav?n & Jos? A. del R?o. (2009) New insights into cellular prion protein (PrPc) functions: The ?ying and yang? of a relevant protein. Brain Research Reviews 61:2, pages 170-184.
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Jerzy Krupinski, Marta M. Turu, Ana Luque, Lina Badimon & Mark Slevin. (2008) Increased PrPC expression correlates with endoglin (CD105) positive microvessels in advanced carotid lesions. Acta Neuropathologica 116:5, pages 537-545.
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