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Research Paper

Gene microarray analysis of human renal cell carcinoma: The effects of HDAC inhibition and retinoid treatment

Pages 1607-1618 | Published online: 01 Oct 2008

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Peter Kovacic & Corey L. Edwards. (2011) Hydroxamic acids (therapeutics and mechanism): chemistry, acyl nitroso, nitroxyl, reactive oxygen species, and cell signaling. Journal of Receptors and Signal Transduction 31:1, pages 10-19.
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Krysta M. DiKun & Lorraine J. Gudas. (2023) Vitamin A and retinoid signaling in the kidneys. Pharmacology & Therapeutics 248, pages 108481.
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Benedikt Linder, Miroslava Zoldakova, Zsuzsanna Kornyei, Leonhard H. F. Köhler, Sebastian Seibt, Dominic Menger, André Wetzel, Emília Madarász, Rainer Schobert, Donat Kögel & Bernhard Biersack. (2022) Antitumor Effects of a New Retinoate of the Fungal Cytotoxin Illudin M in Brain Tumor Models. International Journal of Molecular Sciences 23:16, pages 9056.
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Gizem Ozgun, Serif Senturk & Serap Erkek‐Ozhan. (2020) Retinoic acid signaling and bladder cancer: Epigenetic deregulation, therapy and beyond. International Journal of Cancer 148:10, pages 2364-2374.
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Ana M. Molina, Johannes C. van der Mijn, Paul Christos, John Wright, Charlene Thomas, Janice P. Dutcher, David M. Nanus, Scott T. Tagawa & Lorraine J. Gudas. (2020) NCI 6896: a phase I trial of vorinostat (SAHA) and isotretinoin (13-cis retinoic acid) in the treatment of patients with advanced renal cell carcinoma. Investigational New Drugs 38:5, pages 1383-1389.
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Aysegul Caliskan, Ahmet Cenk Andac & Kazim Yalcin Arga. (2020) Novel molecular signatures and potential therapeutics in renal cell carcinomas: Insights from a comparative analysis of subtypes. Genomics 112:5, pages 3166-3178.
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Joseph L. Napoli. 2020. Retinoid Signaling Pathways. Retinoid Signaling Pathways 27 54 .
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Pratim Chowdhury, Reid T. Powell, Clifford Stephan, Ivan P. Uray, Tia Talley, Menuka Karki, Durga Nand Tripathi, Yong Sung Park, Michael A. Mancini, Peter Davies & Ruhee Dere. (2018) Bexarotene – a novel modulator of AURKA and the primary cilium in VHL -deficient cells . Journal of Cell Science.
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Niraj Shenoy, Nishanth Vallumsetla, Yiyu Zou, Jose Nahun Galeas, Makardhwaj Shrivastava, Caroline Hu, Katalin Susztak & Amit Verma. (2015) Role of DNA methylation in renal cell carcinoma. Journal of Hematology & Oncology 8:1.
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Ki Cheong Park, Jun Hyeok Heo, Jeong Yong Jeon, Hye Ji Choi, A Ra Jo, Seung Won Kim, Ho Jeong Kwon, Sung Joon Hong & Kyung Seok Han. (2015) The novel histone deacetylase inhibitor, N-hydroxy-7-(2-naphthylthio) hepatonomide, exhibits potent antitumor activity due to cytochrome-c-release-mediated apoptosis in renal cell carcinoma cells. BMC Cancer 15:1.
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Xiulan Liu, Jun Wang, Hongjie Wang, Guoxiao Yin, Yang Liu, Xiang Lei & Ming Xiang. (2015) REG3A accelerates pancreatic cancer cell growth under IL-6-associated inflammatory condition: Involvement of a REG3A?JAK2/STAT3 positive feedback loop. Cancer Letters 362:1, pages 45-60.
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Mohammad Hojjat-Farsangi. (2015) Novel and emerging targeted-based cancer therapy agents and methods. Tumor Biology 36:2, pages 543-556.
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Xiaoguang Zhou, Yanis Tolstov, Aysenur Arslan, Wilfried Roth, Carsten Grüllich, Sascha Pahernik, Markus Hohenfellner & Stefan Duensing. (2014) Harnessing the p53-PUMA Axis to Overcome DNA Damage Resistance in Renal Cell Carcinoma. Neoplasia 16:12, pages 1028-1035.
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INGA PETERS, KAI GEBAUER, NATALIA DUBROWINSKAJA, FARANAZ ATSCHEKZEI, MARIO W. KRAMER, JOERG HENNENLOTTER, HOSSEIN TEZVAL, MAHMOUD ABBAS, RALPH SCHERER, AXEL S. MERSEBURGER, ARNULF STENZL, MARKUS A. KUCZYK & JUERGEN SERTH. (2014) GATA5 CpG island hypermethylation is an independent predictor for poor clinical outcome in renal cell carcinoma. Oncology Reports 31:4, pages 1523-1530.
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Nilda Gonzalez-Roibon, Sheila F. Faraj, Enrico Munari, Stephania M. Bezerra, Roula Albadine, Rajni Sharma, Pedram Argani, Mohamad E. Allaf & George J. Netto. (2014) Comprehensive profile of GATA binding protein 3 immunohistochemical expression in primary and metastatic renal neoplasms. Human Pathology 45:2, pages 244-248.
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Alison Urvalek, Kristian Bruun Laursen & Lorraine J. Gudas. 2014. The Biochemistry of Retinoic Acid Receptors I: Structure, Activation, and Function at the Molecular Level. The Biochemistry of Retinoic Acid Receptors I: Structure, Activation, and Function at the Molecular Level 129 149 .
Swathi Ramakrishnan & Roberto Pili. (2013) Histone Deacetylase Inhibitors and Epigenetic Modifications as a Novel Strategy in Renal Cell Carcinoma. The Cancer Journal 19:4, pages 333-340.
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Miriam Schiffgen, Doris H. Schmidt, Alexander von Rücker, Stefan C. Müller & Jörg Ellinger. (2013) Epigenetic regulation of microRNA expression in renal cell carcinoma. Biochemical and Biophysical Research Communications 436:1, pages 79-84.
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Jayashree Ramana. (2012) RCDB: Renal Cancer Gene Database. BMC Research Notes 5:1.
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R Pili, B Salumbides, M Zhao, S Altiok, D Qian, J Zwiebel, M A Carducci & M A Rudek. (2011) Phase I study of the histone deacetylase inhibitor entinostat in combination with 13-cis retinoic acid in patients with solid tumours. British Journal of Cancer 106:1, pages 77-84.
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Swathi Ramakrishnan & Roberto Pili. 2012. Renal Cell Carcinoma. Renal Cell Carcinoma 193 211 .
Xiao-Han TangLorraine J. Gudas. (2011) Retinoids, Retinoic Acid Receptors, and Cancer. Annual Review of Pathology: Mechanisms of Disease 6:1, pages 345-364.
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Soledad Negrotto, Zhenbo Hu, Oscar Alcazar, Kwok Peng Ng, Pierre Triozzi, Daniel Lindner, Brian Rini & Yogen Saunthararajah. (2011) Noncytotoxic Differentiation Treatment of Renal Cell Cancer. Cancer Research 71:4, pages 1431-1441.
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Marcella M Baldewijns, Iris JH van Vlodrop, Peter B Vermeulen, Patricia MMB Soetekouw, Manon van Engeland & Adriaan P de Bruïne. (2010) VHL and HIF signalling in renal cell carcinogenesis. The Journal of Pathology 221:2, pages 125-138.
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S J Cooper, H Zou, S N LeGrand, L A Marlow, C A von Roemeling, D C Radisky, K J Wu, N Hempel, V Margulis, H W Tun, G C Blobe, C G Wood & J A Copland. (2010) Loss of type III transforming growth factor-β receptor expression is due to methylation silencing of the transcription factor GATA3 in renal cell carcinoma. Oncogene 29:20, pages 2905-2915.
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Kateřina Kuželová, Michaela Pluskalová, Barbora Brodská, Petra Otevřelová, Klára Elknerová, Dana Grebeňová & Zbyněk Hrkal. (2010) Suberoylanilide hydroxamic acid (SAHA) at subtoxic concentrations increases the adhesivity of human leukemic cells to fibronectin. Journal of Cellular Biochemistry 109:1, pages 184-195.
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Melissa J LaBonte, Peter M Wilson, William Fazzone, Susan Groshen, Heinz-Josef Lenz & Robert D Ladner. (2009) DNA microarray profiling of genes differentially regulated by the histone deacetylase inhibitors vorinostat and LBH589 in colon cancer cell lines. BMC Medical Genomics 2:1.
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Limin Liu, Fadila Derguini & Lorraine J. Gudas. (2009) Metabolism and regulation of gene expression by 4-oxoretinol versus all- trans retinoic acid in normal human mammary epithelial cells . Journal of Cellular Physiology 220:3, pages 771-779.
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H. Nian, W. H. Bisson, W.-M. Dashwood, J. T. Pinto & R. H. Dashwood. (2009)  -Keto acid metabolites of organoselenium compounds inhibit histone deacetylase activity in human colon cancer cells. Carcinogenesis 30:8, pages 1416-1423.
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