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Research Paper

A combination of Trastuzumab and 17-AAG induces enhanced ubiquitinylation and lysosomal pathway-dependent ErbB2 degradation and cytotoxicity in ErbB2-overexpressing breast cancer cells

Pages 1630-1640 | Published online: 01 Oct 2008

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Srikumar M. Raja, Robert J. Clubb, Cesar Ortega-Cava, Stetson H. Williams, Tameka A. Bailey, Lei Duan, Xiangshan Zhao, Alagarasamy L. Reddi, Abijah M. Nyong, Amarnath Natarajan, Vimla Band & Hamid Band. (2011) Anticancer activity of Celastrol in combination with ErbB2-targeted therapeutics for treatment of ErbB2-overexpressing breast cancers. Cancer Biology & Therapy 11:2, pages 263-276.
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