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Research Paper

Silencing of Wnt-1 by siRNA induces apoptosis of MCF-7 human breast cancer cells

Pages 268-274 | Published online: 04 Feb 2008

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Yunching Chen & Leaf Huang. (2008) Tumor-targeted delivery of siRNA by non-viral vector: safe and effective cancer therapy. Expert Opinion on Drug Delivery 5:12, pages 1301-1311.
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Jafar Poodineh, Majid Sirati‐Sabet, Masoumeh Rajabibazl, Majid Ghasemian & Samira Mohammadi‐Yeganeh. (2022) Downregulation of NRARP exerts anti‐tumor activities in the breast tumor cells depending on Wnt/β‐catenin‐mediated signals: The role of miR ‐130a‐3p . Chemical Biology & Drug Design 100:3, pages 334-345.
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Shokooh Salimimoghadam, Sina Taefehshokr, Reid Loveless, Yong Teng, Gloria Bertoli, Nima Taefehshokr, Fatemeh Musaviaroo, Khalil Hajiasgharzadeh & Behzad Baradaran. (2021) The role of tumor suppressor short non-coding RNAs on breast cancer. Critical Reviews in Oncology/Hematology 158, pages 103210.
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Dian-Hui Xiu, Gui-Feng Liu, Shao-Nan Yu, Long-Yun Li, Guo-Qing Zhao, Lin Liu & Xue-Feng Li. (2019) RETRACTED ARTICLE: Long non-coding RNA LINC00968 attenuates drug resistance of breast cancer cells through inhibiting the Wnt2/β-catenin signaling pathway by regulating WNT2. Journal of Experimental & Clinical Cancer Research 38:1.
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Changpo Ma, Xuejun Shi, Wenchao Guo, Jianxin Niu & Guangshun Wang. (2019) miR-107 enhances the sensitivity of breast cancer cells to paclitaxel. Open Medicine 14:1, pages 456-466.
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Liang Wu, Fulai Pei, Xiaojuan Men, Kai Wang & Deliang Ma. (2018) miR‑329 inhibits papillary thyroid cancer progression via direct targeting WNT1. Oncology Letters.
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Xiao‑Li Zheng & Hong‑Gang Yu. (2018) Wnt6 contributes tumorigenesis and development of colon cancer via its effects on cell proliferation, apoptosis, cell‑cycle and migration. Oncology Letters.
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Zhejia Zhang, Xinying Li, Qian Xiao & Zhiming Wang. (2018) MiR-574-5p mediates the cell cycle and apoptosis in thyroid cancer cells via Wnt/β-catenin signaling by repressing the expression of Quaking proteins. Oncology Letters.
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Zeinab Ahsani, Samira Mohammadi-Yeganeh, Vahid Kia, Hamzeh Karimkhanloo, Nosratollah Zarghami & Mahdi Paryan. (2016) WNT1 Gene from WNT Signaling Pathway Is a Direct Target of miR-122 in Hepatocellular Carcinoma. Applied Biochemistry and Biotechnology 181:3, pages 884-897.
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Fatten F. Elkomy, Andrew J. Levine, Elyse Singer, Charurut Somboonwit, Todd Wills, Kaley Tash, John T. Sinnott, Sally Alrabaa, Anteneh Addisu, Hector Rodriguez, Francesco Chiappelli, Toni Kazic & Paul Shapshak. 2017. Global Virology II - HIV and NeuroAIDS. Global Virology II - HIV and NeuroAIDS 533 578 .
Chong-Kuei Lii, Jer-Wei Chang, Jia-Jing Chen, Haw-Wen Chen, Kai-Li Liu, Shu-Lan Yeh, Tsu-Shing Wang, Shu-Hui Liu, Chia-Han Tsai & Chien-Chun Li. (2016) Docosahexaenoic acid inhibits 12- O -tetradecanoylphorbol-13- acetate-induced fascin-1-dependent breast cancer cell migration by suppressing the PKCδ- and Wnt-1/β-catenin-mediated pathways . Oncotarget 7:18, pages 25162-25179.
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Marzena Szwed, Katarzyna D. Kania & Zofia Jozwiak. (2015) Toxicity of doxorubicin-transferrin conjugate is connected to the modulation of Wnt/β-catenin pathway in human leukemia cells. Leukemia Research 39:10, pages 1096-1102.
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Maria Mazur, Anna Bujak, Mikolaj Matloka, Sylwia Janowska, Pawel Gunerka, Lukasz Bojarski, Aleksandra Stanczak, Agata Klejman, Andrzej Bednarek, Monika Lamparska-Przybysz & Maciej Wieczorek. (2015) Cell-based assay for low- and high-scale screening of the Wnt/β-catenin signaling modulators. Analytical Biochemistry 475, pages 56-67.
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Jun-gang Zhang, Ying Shi, De-fei Hong, Mengqi Song, Dongsheng Huang, Chun-you Wang & Gang Zhao. (2015) MiR-148b suppresses cell proliferation and invasion in hepatocellular carcinoma by targeting WNT1/β-catenin pathway. Scientific Reports 5:1.
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LUN DONG, XIAO-CHUN DUAN, CHONG-XU HAN, HENGZHU ZHANG & YONGKANG WU. (2015) Suppression of wingless-type MMTV integration site family, member 1 expression by small interfering RNA inhibits U251 glioma cell growth in vitro. Oncology Letters 9:1, pages 81-85.
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K. M. Pawłowski, D. Popielarz, K. Szyszko, M. Gajewska, T. Motyl & M. Król. (2011) Growth hormone receptor ( ghr ) RNAi decreases proliferation and enhances apoptosis in CMT‐U27 canine mammary carcinoma cell line . Veterinary and Comparative Oncology 10:1, pages 2-15.
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Peggy Benad, Martina Rauner, Tilman D. Rachner & Lorenz C. Hofbauer. (2011) The anti-progestin RU-486 inhibits viability of MCF-7 breast cancer cells by suppressing WNT1. Cancer Letters 312:1, pages 101-108.
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Yu Yin, Zhengduo Yang & Shiwu Zhang. (2011) Combined treatment with exogenous estradiol and progesterone increases the incidence of breast cancer in TA2 mice without ovaries. Cancer Letters 311:2, pages 171-176.
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Roman Anton, Sujash S. Chatterjee, Julia Simundza, Pamela Cowin & Ramanuj DasGupta. (2011) A Systematic Screen for Micro-RNAs Regulating the Canonical Wnt Pathway. PLoS ONE 6:10, pages e26257.
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Tao Lin, Lingjun Meng, Yi Li & Robert Y.L. Tsai. (2010) Tumor-Initiating Function of Nucleostemin-Enriched Mammary Tumor Cells. Cancer Research 70:22, pages 9444-9452.
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Jin LvXiu-Feng CaoLv JiBin ZhuLei TaoDong-Dong Wang. (2010) Association of Wnt1/β-Catenin with Clinical Pathological Characteristics and Prognosis of Esophageal Squamous Cell Carcinoma . Genetic Testing and Molecular Biomarkers 14:3, pages 363-369.
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James S. Lawson, Wendy K. Glenn, Brian Salmons, Yulan Ye, Benjamin Heng, Patrick Moody, Harpreet Johal, William D. Rawlinson, Warick Delprado, Louise Lutze-Mann & Noel J. Whitaker. (2010) Mouse Mammary Tumor Virus–like Sequences in Human Breast Cancer. Cancer Research 70:9, pages 3576-3585.
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Z. Liu & J. F. Habener. (2009) Stromal cell-derived factor-1 promotes survival of pancreatic beta cells by the stabilisation of beta-catenin and activation of transcription factor 7-like 2 (TCF7L2). Diabetologia 52:8, pages 1589-1598.
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Yu-Cheng Tseng, Subho Mozumdar & Leaf Huang. (2009) Lipid-based systemic delivery of siRNA. Advanced Drug Delivery Reviews 61:9, pages 721-731.
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Hye-Jin Min, Il-Rae Cho, Ratakorn Srisuttee, Eun-Hee Park, Dae Ho Cho, Jin-Hyun Ahn, Im-Soon Lee, Randal N. Johnston, Sangtaek Oh & Young-Hwa Chung. (2009) Hexachlorophene suppresses β-catenin expression by up-regulation of Siah-1 in EBV-infected B lymphoma cells. Cancer Letters 276:2, pages 136-142.
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