453
Views
60
CrossRef citations to date
0
Altmetric
Research Paper

The metastasis-associated gene MTA1 is upregulated in advanced ovarian cancer, represses ERβ, and enhances expression of oncogenic cytokine GRO

Pages 1460-1467 | Published online: 01 Sep 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Sharareh Siamakpour-Reihani, Kouros Owzar, Chen Jiang, Peter M. Scarbrough, Oana I. Craciunescu, Janet K. Horton, Holly K. Dressman, Kimberly L. Blackwell & Mark W. Dewhirst. (2015) Genomic profiling in locally advanced and inflammatory breast cancer and its link to DCE-MRI and overall survival. International Journal of Hyperthermia 31:4, pages 386-395.
Read now
Marie-Luise Buchholtz, Julia Jückstock, Elena Weber, Ioannis Mylonas, Darius Dian & Ansgar Brüning. (2013) Loss of LDOC1 Expression by Promoter Methylation in Cervical Cancer Cells. Cancer Investigation 31:9, pages 571-577.
Read now

Articles from other publishers (58)

Giulia Wanka, Julia Jueckstock, Carl Mathis Wild, Aurelia Vattai, Sophie Fürst, Helene H. Heidegger, Christina Kuhn, Elisa Schmoeckel, Udo Jeschke & Christian Dannecker. (2023) MTA1 as negative prognostic marker in vulvar carcinoma. Journal of Cancer Research and Clinical Oncology 149:9, pages 6191-6201.
Crossref
Jan Korbecki, Mateusz Bosiacki, Katarzyna Barczak, Ryta Łagocka, Agnieszka Brodowska, Dariusz Chlubek & Irena Baranowska-Bosiacka. (2023) Involvement in Tumorigenesis and Clinical Significance of CXCL1 in Reproductive Cancers: Breast Cancer, Cervical Cancer, Endometrial Cancer, Ovarian Cancer and Prostate Cancer. International Journal of Molecular Sciences 24:8, pages 7262.
Crossref
Ieva Vaicekauskaitė, Rasa Sabaliauskaitė, Juozas Rimantas Lazutka & Sonata Jarmalaitė. (2022) The Emerging Role of Chromatin Remodeling Complexes in Ovarian Cancer. International Journal of Molecular Sciences 23:22, pages 13670.
Crossref
Jialu Ma, Chunxiao Li, Haili Qian & Yong Zhang. (2022) MTA1: A Vital Modulator in Prostate Cancer. Current Protein & Peptide Science 23:7, pages 456-464.
Crossref
Chaitanya Vattem & Suresh B Pakala. (2022) Metastasis-associated protein 1: A potential driver and regulator of the hallmarks of cancer. Journal of Biosciences 47:2.
Crossref
Anu Bansal, Vikas Kaushik & Neeta Raj Sharma. (2022) Synthesis and in silico anti-metastatic evaluation of carvacrol derivative, 2-hydroxy-6-isopropyl-3-methylbenzalehyde. Materials Today: Proceedings 57, pages 739-747.
Crossref
Mizuho Ishikawa, Mitsuhiko Osaki, Narumi Uno, Takahito Ohira, Hiroyuki Kugoh & Futoshi Okada. (2021) MTA1, a metastasis‑associated protein, in endothelial cells is an essential molecule for angiogenesis. Molecular Medicine Reports 25:1.
Crossref
Eun B. Lee, V. Praveen Chakravarthi, Michael W. Wolfe & M. A. Karim Rumi. (2021) ERβ Regulation of Gonadotropin Responses during Folliculogenesis. International Journal of Molecular Sciences 22:19, pages 10348.
Crossref
Cai Lv, Yuan Huang, Qingqing Lei, Zhenxiang Liu, Shixing Shen & Wenxia Si. (2020) Elevated MTA1 induced the migration and invasion of renal cell carcinoma through the NF-κB pathway. BMC Urology 20:1.
Crossref
Cuina Han, Fangfei Zhao, Chongyang Wan, Yanfang He & Yan Chen. (2020) Associations between the expression of SCCA, MTA1, P16, Ki‑67 and the infection of high‑risk HPV in cervical lesions. Oncology Letters.
Crossref
Xiaofeng Xu, Xiangyi Kong, Tao Liu, Ling Zhou, Jun Wu, Jian Fu, Yijin Wang, Mengjing Zhu, Shuang Yao, Yue Ding, Ling Ding, Rong Li, Xianghong Zhu, Xiaoqiu Tang, Yan Zhang, Qian Yang, Jingxian Ling & Huaijun Zhou. (2019) Metastasis-associated protein 1, modulated by miR-30c, promotes endometrial cancer progression through AKT/mTOR/4E-BP1 pathway. Gynecologic Oncology 154:1, pages 207-217.
Crossref
Mizuho Ishikawa, Mitsuhiko Osaki, Makoto Yamagishi, Kunishige Onuma, Hisao Ito, Futoshi Okada & Hideya Endo. (2019) Correlation of two distinct metastasis-associated proteins, MTA1 and S100A4, in angiogenesis for promoting tumor growth. Oncogene 38:24, pages 4715-4728.
Crossref
Yu-yuan Qian, Zhi-su Liu, Hua-jun Yan, Yu-feng Yuan, Anait S. Levenson & Kun Li. (2018) Pterostilbene inhibits MTA1/HDAC1 complex leading to PTEN acetylation in hepatocellular carcinoma. Biomedicine & Pharmacotherapy 101, pages 852-859.
Crossref
Zan-Feng Xu, Xiao-Ke Sun, Gang Chen, Chao Han, Feng Wang & Yong-Dong Zhang. (2018) Oroxyloside inhibits human glioma progression by suppressing proliferation, metastasis and inducing apoptosis related pathways. Biomedicine & Pharmacotherapy 97, pages 1564-1574.
Crossref
Liang Du, Zhifeng Ning, Fuxing Liu & Hao Zhang. (2017) Corepressor metastasis-associated protein 3 modulates epithelial-to-mesenchymal transition and metastasis. Chinese Journal of Cancer 36:1.
Crossref
Yu-Yuan Qian, Zhi-Su Liu, Ding-Yu Pan & Kun Li. (2017) Tumoricidal activities of pterostilbene depend upon destabilizing the MTA1-NuRD complex and enhancing P53 acetylation in hepatocellular carcinoma. Experimental and Therapeutic Medicine 14:4, pages 3098-3104.
Crossref
Xizhou Lin, Liang Zheng, Hongliang Song, Jun Xiao, Bujian Pan, Haichuan Chen, Xiaodan Jin & Haibo Yu. (2017) Effects of microRNA-183 on epithelial-mesenchymal transition, proliferation, migration, invasion and apoptosis in human pancreatic cancer SW1900 cells by targeting MTA1. Experimental and Molecular Pathology 102:3, pages 522-532.
Crossref
Yi-Liang Wu, Nan-Yung Hsu, Frank Cheau-Feng Lin, Huei Lee & Ya-Wen Cheng. (2016) MiR-30c-2* negative regulated MTA-1 expression involved in metastasis and drug resistance of HPV-infected non-small cell lung cancer. Surgery 160:6, pages 1591-1598.
Crossref
Yoshinaga Okugawa, Yasuhiko Mohri, Koji Tanaka, Mikio Kawamura, Susumu Saigusa, Yuji Toiyama, Masaki Ohi, Yasuhiro Inoue, Chikao Miki & Masato Kusunoki. (2016) Metastasis-associated protein is a predictive biomarker for metastasis and recurrence in gastric cancer. Oncology Reports 36:4, pages 1893-1900.
Crossref
R Kumar, D-Q Li, S Müller & S Knapp. (2016) Epigenomic regulation of oncogenesis by chromatin remodeling. Oncogene 35:34, pages 4423-4436.
Crossref
S. Tunçer, S. Tunçay Çağatay, A.G. Keşküş, M. Çolakoğlu, Ö. Konu & S. Banerjee. (2016) Interplay between 15-lipoxygenase-1 and metastasis-associated antigen 1 in the metastatic potential of colorectal cancer. Cell Proliferation 49:4, pages 448-459.
Crossref
Kazufumi Ohshiro & Rakesh Kumar. (2015) MTA1 regulation of ERβ pathway in salivary gland carcinoma cells. Biochemical and Biophysical Research Communications 464:4, pages 1016-1021.
Crossref
Loredana Campo, Catherine Zhang & Eun-Kyoung Breuer. (2015) EMT-Inducing Molecular Factors in Gynecological Cancers. BioMed Research International 2015, pages 1-12.
Crossref
Da-Qiang Li & Rakesh Kumar. 2015. 1 47 .
Evelyn Despierre, Matthieu Moisse, Betül Yesilyurt, Jalid Sehouli, Ioana Braicu, Sven Mahner, Dan Cacsire Castillo-Tong, Robert Zeillinger, Sandrina Lambrechts, Karin Leunen, Frédéric Amant, Philippe Moerman, Diether Lambrechts & Ignace Vergote. (2014) Somatic copy number alterations predict response to platinum therapy in epithelial ovarian cancer. Gynecologic Oncology 135:3, pages 415-422.
Crossref
Ekjot Kaur, Sudeep Gupta & Shilpee Dutt. (2014) Clinical implications of MTA proteins in human cancer. Cancer and Metastasis Reviews 33:4, pages 1017-1024.
Crossref
Sung Sun Kim & Yong-Koo Park. (2014) Significance of MTA1 in the molecular characterization of osteosarcoma. Cancer and Metastasis Reviews 33:4, pages 981-991.
Crossref
Soo Hyung Ryu, Myoung Kuk Jang, Woo Jean Kim, Danbi Lee & Young-Hwa Chung. (2014) Metastatic tumor antigen in hepatocellular carcinoma: golden roads toward personalized medicine. Cancer and Metastasis Reviews 33:4, pages 965-980.
Crossref
Hezlin Marzook, S. Deivendran, Rakesh Kumar & M. Radhakrishna Pillai. (2014) Role of MTA1 in head and neck cancers. Cancer and Metastasis Reviews 33:4, pages 953-964.
Crossref
Ansgar Brüning, Thomas Blankenstein, Julia Jückstock & Ioannis Mylonas. (2014) Function and regulation of MTA1 and MTA3 in malignancies of the female reproductive system. Cancer and Metastasis Reviews 33:4, pages 943-951.
Crossref
Anait S. Levenson, Avinash Kumar & Xu Zhang. (2014) MTA family of proteins in prostate cancer: biology, significance, and therapeutic opportunities. Cancer and Metastasis Reviews 33:4, pages 929-942.
Crossref
Yasushi Toh & Garth L. Nicolson. (2014) Properties and clinical relevance of MTA1 protein in human cancer. Cancer and Metastasis Reviews 33:4, pages 891-900.
Crossref
Jian Liu, Haijuan Wang, Changzhi Huang & Haili Qian. (2014) Subcellular localization of MTA proteins in normal and cancer cells. Cancer and Metastasis Reviews 33:4, pages 843-856.
Crossref
Heying Chu, Xudong Chen, Huaqi Wang, Yuwen Du, Yuanyuan Wang, Wenqiao Zang, Ping Li, Juan Li, Jingxia Chang, Guoqiang Zhao & Guojun Zhang. (2013) MiR-495 regulates proliferation and migration in NSCLC by targeting MTA3. Tumor Biology 35:4, pages 3487-3494.
Crossref
Shanshan Hong, Xiaoyan Zhang, Jun Chen, Jiabing Zhou, Yufang Zheng & Congjian Xu. (2013) Targeted gene silencing using a follicle-stimulating hormone peptide-conjugated nanoparticle system improves its specificity and efficacy in ovarian clear cell carcinoma in vitro. Journal of Ovarian Research 6:1.
Crossref
Shangen Zheng, Yuwen Du, Heying Chu, Xudong Chen, Ping Li, Yuanyuan Wang, Yunyun Ma, Huaqi Wang, Wenqiao Zang, Guojun Zhang & Guoqiang Zhao. (2013) Analysis of MAT3 gene expression in NSCLC. Diagnostic Pathology 8:1.
Crossref
Haiying Li, Liangliang Sun, Ying Xu, Zixuan Li, Wenting Luo, Zhongping Tang, Xueshan Qiu & Enhua Wang. (2013) Overexpression of MTA3 Correlates with Tumor Progression in Non-Small Cell Lung Cancer. PLoS ONE 8:6, pages e66679.
Crossref
Hongmei Dong, Hong Guo, Liangxi Xie, Geng Wang, Xueyun Zhong, Thaer Khoury, Dongfeng Tan & Hao Zhang. (2013) The Metastasis-Associated Gene MTA3, a Component of the Mi-2/NuRD Transcriptional Repression Complex, Predicts Prognosis of Gastroesophageal Junction Adenocarcinoma. PLoS ONE 8:5, pages e62986.
Crossref
Seda Tuncay Cagatay, Ismail Cimen, Berna Savas & Sreeparna Banerjee. (2013) MTA-1 expression is associated with metastasis and epithelial to mesenchymal transition in colorectal cancer cells. Tumor Biology 34:2, pages 1189-1204.
Crossref
Yu-mei Rao, Mei Ji, Cai-hong Chen & Hui-rong Shi. (2013) Effect of siRNA targeting MTA1 on metastasis malignant phenotype of ovarian cancer A2780 cells. Journal of Huazhong University of Science and Technology [Medical Sciences] 33:2, pages 266-271.
Crossref
Yasushi Toh & Garth L. Nicolson. 2013. Trends in Stem Cell Proliferation and Cancer Research. Trends in Stem Cell Proliferation and Cancer Research 251 275 .
Hongyan Wang, Liangsheng Fan, Juncheng Wei, Yanjie Weng, Li Zhou, Ying Shi, Wenjuan Zhou, Ding Ma & Changyu Wang. (2012) Akt Mediates Metastasis-Associated Gene 1 (MTA1) Regulating the Expression of E-cadherin and Promoting the Invasiveness of Prostate Cancer Cells. PLoS ONE 7:12, pages e46888.
Crossref
Katherine A. Burns & Kenneth S. Korach. (2012) Estrogen receptors and human disease: an update. Archives of Toxicology 86:10, pages 1491-1504.
Crossref
Claudia PalenaDuane H Hamilton & Romaine I Fernando. (2012) Influence of IL-8 on the epithelial–mesenchymal transition and the tumor microenvironment. Future Oncology 8:6, pages 713-722.
Crossref
Ioannis Mylonas & Ansgar Brüning. (2012) The metastasis‐associated gene MTA3 is an independent prognostic parameter in uterine non‐endometrioid carcinomas . Histopathology 60:4, pages 665-670.
Crossref
Maria Grazia Prisco, Gian Franco Zannoni, Ilaria De Stefano, Valerio Gaetano Vellone, Lucia Tortorella, Anna Fagotti, Liliana Mereu, Giovanni Scambia & Daniela Gallo. (2012) Prognostic role of metastasis tumor antigen 1 in patients with ovarian cancer: a clinical study. Human Pathology 43:2, pages 282-288.
Crossref
Da-Qiang Li, Suresh B. Pakala, Sujit S. Nair, Jeyanthy Eswaran & Rakesh Kumar. (2012) Metastasis-Associated Protein 1/Nucleosome Remodeling and Histone Deacetylase Complex in Cancer. Cancer Research 72:2, pages 387-394.
Crossref
LIANGSHENG FAN, HONGYAN WANG, XI XIA, YUMEI RAO, XIANGYI MA, DING MA, PENG WU & GANG CHEN. (2012) Loss of E-cadherin promotes prostate cancer metastasis via upregulation of metastasis-associated gene 1 expression. Oncology Letters 4:6, pages 1225-1233.
Crossref
YASUHITO TANASE, YOSHIHIKO YAMADA, HIROSHI SHIGETOMI, HIROTAKA KAJIHARA, AKIRA OONOGI, YORIKO YOSHIZAWA, NAOTO FURUKAWA, SHOJI HARUTA, SHOZO YOSHIDA, TOSHIYUKI SADO, HIDEKAZU OI & HIROSHI KOBAYASHI. (2012) Modulation of estrogenic action in clear cell carcinoma of the ovary (Review). Experimental and Therapeutic Medicine 3:1, pages 18-24.
Crossref
Romaine I. Fernando, Marianne D. Castillo, Mary Litzinger, Duane H. Hamilton & Claudia Palena. (2011) IL-8 Signaling Plays a Critical Role in the Epithelial–Mesenchymal Transition of Human Carcinoma Cells. Cancer Research 71:15, pages 5296-5306.
Crossref
Darius Dian, Ansgar Brüning & Ioannis Mylonas. (2010) E-cadherin as a prognostic marker in human serous carcinomas of the ovary: an immunohistochemical analysis. Archives of Gynecology and Obstetrics 284:2, pages 437-443.
Crossref
S B Pakala, K Singh, S D N Reddy, K Ohshiro, D-Q Li, L Mishra & R Kumar. (2011) TGF-β1 signaling targets metastasis-associated protein 1, a new effector in epithelial cells. Oncogene 30:19, pages 2230-2241.
Crossref
Li Kai, Jun Wang, Marina Ivanovic, Yeon‐Tae Chung, William B. Laskin, Frank Schulze‐Hoepfner, Yelena Mirochnik, Robert L. SatcherJr.Jr. & Anait S. Levenson. (2010) Targeting prostate cancer angiogenesis through metastasis‐associated protein 1 (MTA1). The Prostate 71:3, pages 268-280.
Crossref
Yumei Rao, Hongyan Wang, Liangsheng Fan & Gang Chen. (2011) Silencing MTA1 by RNAi reverses adhesion, migration and invasiveness of cervical cancer cells (SiHa) via altered expression of p53, and E-cadherin/β-catenin complex. Journal of Huazhong University of Science and Technology [Medical Sciences] 31:1, pages 1-9.
Crossref
Alexander Burges, Ansgar Brüning, Christine Dannenmann, Thomas Blankenstein, Udo Jeschke, Naim Shabani, Klaus Friese & Ioannis Mylonas. (2009) Prognostic significance of estrogen receptor alpha and beta expression in human serous carcinomas of the ovary. Archives of Gynecology and Obstetrics 281:3, pages 511-517.
Crossref
Keiko Abe, Yasuhiro Miki, Katsuhiko Ono, Miki Mori, Hideaki Kakinuma, Yuki Kou, Nobutaka Kudo, Masashi Koguchi, Hiromichi Niikawa, Satoshi Suzuki, Dean B. Evans, Shunichi Sugawara, Takashi Suzuki & Hironobu Sasano. (2010) Highly concordant coexpression of aromatase and estrogen receptor β in non–small cell lung cancer. Human Pathology 41:2, pages 190-198.
Crossref
Ansgar Brüning, Josef Makovitzky, Andrea Gingelmaier, Klaus Friese & Ioannis Mylonas. (2009) The metastasis-associated genes MTA1 and MTA3 are abundantly expressed in human placenta and chorionic carcinoma cells. Histochemistry and Cell Biology 132:1, pages 33-38.
Crossref
Yasushi Toh & Garth L. Nicolson. (2008) The role of the MTA family and their encoded proteins in human cancers: molecular functions and clinical implications. Clinical & Experimental Metastasis 26:3, pages 215-227.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.