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Cancer Biology & Therapy Volume 8, 2009 - Issue 10
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Research Paper

Histopathological analyses of the antitumor activity of anti-glypican-3 antibody (GC33) in human liver cancer xenograft models: The essential role of macrophages

Hirotake Takai
,
Atsuhiko Kato
,
Yasuko Kinoshita
,
Takahiro Ishiguro
,
Yayoi Takai
,
Yoshimi Ohtani
,
Masamichi Sugimoto
&
Masami Suzuki
 show all
Pages 930-938 | Published online: 15 May 2009

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Kazuya Ofuji, Keigo Saito, Toshiaki Yoshikawa & Tetsuya Nakatsura. (2014) Critical analysis of the potential of targeting GPC3 in hepatocellular carcinoma. Journal of Hepatocellular Carcinoma 1, pages 35-42.
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Articles from other publishers (16)

Jun‐Hua Nie, Tao Yang, Hong Li, Sheng Li, Ting‐Ting Li, Hai‐Shan Ye, Meng‐Di Lu, Xiao Chu, Guo‐Qing Zhong, Jie‐Long Zhou, Mo‐Li Wu, Yu Zhang & Jia Liu. (2022) Frequently expressed glypican‐3 as a promising novel therapeutic target for osteosarcomas. Cancer Science 113:10, pages 3618-3632.
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Dan Li, Shaoli Lin, Jessica Hong & Mitchell Ho. 2022. Hepatobiliary Cancers: Translational Advances and Molecular Medicine. Hepatobiliary Cancers: Translational Advances and Molecular Medicine 415 449 .
Anita Bakrania, Gang Zheng & Mamatha Bhat. (2021) Nanomedicine in Hepatocellular Carcinoma: A New Frontier in Targeted Cancer Treatment. Pharmaceutics 14:1, pages 41.
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Mikiko Nakamura, Chao Xu, Cheikh Diack, Norihisa Ohishi, Ruey‐min Lee, Satofumi Iida, Takehiko Kawanishi, Toshihiko Ohtomo, Ghassan K. Abou‐Alfa & Ya‐Chi Chen. (2018) Time‐to‐event modelling of effect of codrituzumab on overall survival in patients with hepatocellular carcinoma. British Journal of Clinical Pharmacology 84:5, pages 944-951.
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Fubo Zhou, Wenting Shang, Xiaoling Yu & Jie Tian. (2018) Glypican-3: A promising biomarker for hepatocellular carcinoma diagnosis and treatment. Medicinal Research Reviews 38:2, pages 741-767.
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Cristian Turato, Anna Balasso, Vinicio Carloni, Claudio Tiribelli, Francesca Mastrotto, Antonio Mazzocca & Patrizia Pontisso. (2017) New molecular targets for functionalized nanosized drug delivery systems in personalized therapy for hepatocellular carcinoma. Journal of Controlled Release 268, pages 184-197.
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Hongliang Yao, Zhulin Yang, Ziru Liu, Xiongying Miao, Leping Yang, Daiqiang Li, Qiong Zou & Yuan Yuan. (2017) Glypican-3 and KRT19 are markers associating with metastasis and poor prognosis of pancreatic ductal adenocarcinoma. Cancer Biomarkers 17:4, pages 397-404.
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Yi-Fan Zhang, Jessica Hong & Mitchell Ho. 2017. Immunotherapy of Hepatocellular Carcinoma. Immunotherapy of Hepatocellular Carcinoma 103 119 .
Ghassan K. Abou-Alfa, Oscar Puig, Bruno Daniele, Masatoshi Kudo, Philippe Merle, Joong-Won Park, Paul Ross, Jean-Marie Peron, Oliver Ebert, Stephen Chan, Tung Ping Poon, Massimo Colombo, Takuji Okusaka, Baek-Yeol Ryoo, Beatriz Minguez, Takayoshi Tanaka, Toshihiko Ohtomo, Stacey Ukrainskyj, Frederic Boisserie, Olga Rutman, Ya-Chi Chen, Chao Xu, Eliezer Shochat, Lori Jukofsky, Bernhard Reis, Gong Chen, Laura Di Laurenzio, Ray Lee & Chia-Jui Yen. (2016) Randomized phase II placebo controlled study of codrituzumab in previously treated patients with advanced hepatocellular carcinoma. Journal of Hepatology 65:2, pages 289-295.
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Ying Liu, Dongping Zheng, Mingming Liu, Jiao Bai, Xi Zhou, Baolan Gong, Jieyu Lü, Yi Zhang, Hui Huang, Wenying Luo & Guangrong Huang. (2015) Downregulation of glypican-3 expression increases migration, invasion, and tumorigenicity of human ovarian cancer cells. Tumor Biology 36:10, pages 7997-8006.
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Mingqian Feng & Mitchell Ho. (2014) Glypican-3 antibodies: A new therapeutic target for liver cancer. FEBS Letters 588:2, pages 377-382.
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Yonghai Li, Donald L Siegel, Nathalie Scholler & David E Kaplan. (2012) Validation of glypican-3-specific scFv isolated from paired display/secretory yeast display library. BMC Biotechnology 12:1.
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Daniel H. Palmer & Matthew E. Cramp. 2011. Clinical Dilemmas in Primary Liver Cancer. Clinical Dilemmas in Primary Liver Cancer 199 211 .
Mitchell Ho. (2011) Advances in Liver Cancer Antibody Therapies. BioDrugs 25:5, pages 275-284.
Crossref
Mitchell Ho & Heungnam Kim. (2011) Glypican-3: A new target for cancer immunotherapy. European Journal of Cancer 47:3, pages 333-338.
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Kiyotaka Nakano, Takahiro Ishiguro, Hiroko Konishi, Megumi Tanaka, Masamichi Sugimoto, Izumi Sugo, Tomoyuki Igawa, Hiroyuki Tsunoda, Yasuko Kinoshita, Kiyoshi Habu, Tetsuro Orita, Masayuki Tsuchiya, Kunihiro Hattori & Hisafumi Yamada-Okabe. (2010) Generation of a humanized anti-glypican 3 antibody by CDR grafting and stability optimization. Anti-Cancer Drugs 21:10, pages 907-916.
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