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Research Paper

ERK activation increases nitroprusside induced apoptosis in  human melanoma  cells  irrespective of p53 status: Role of  superoxide dismutases

Pages 1173-1182 | Published online: 15 Jun 2009

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Jaqueline Pereira Moura Soares, Diego Assis Gonçalves, Ricardo Xisto de Sousa, Margareth Gori Mouro, Elisa M. S. Higa, Letícia Paulino Sperandio, Carolina Moraes Vitoriano, Elisa Bachir Santa Rosa, Fernanda Oliveira dos Santos, Gustavo Nery de Queiroz, Roberta Sessa Stilhano Yamaguchi, Gustavo Pereira, Marcelo Yudi Icimoto & Fabiana Henriques Machado de Melo. (2022) Disruption of Redox Homeostasis by Alterations in Nitric Oxide Synthase Activity and Tetrahydrobiopterin along with Melanoma Progression. International Journal of Molecular Sciences 23:11, pages 5979.
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Manuel Rieber, Luis A. Gomez-Sarosi & Mary Strasberg Rieber. (2020) Nitroprusside induces melanoma ferroptosis with serum supplementation and prolongs survival under serum depletion or hypoxia. Biochemical and Biophysical Research Communications 525:3, pages 626-632.
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Yawen Qiang, Fan Ma, Ziran Wang, Zhengchao Nie, Liangfei Xu, Pengsheng Ding & Xiaoling Ma. (2020) LukS-PV induces cell cycle arrest and apoptosis through p38/ERK MAPK signaling pathway in NSCLC cells. Biochemical and Biophysical Research Communications 521:4, pages 846-852.
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Guangya Zhang, Jiangping He, Xiaofei Ye, Jing Zhu, Xi Hu, Minyan Shen, Yuru Ma, Ziming Mao, Huaidong Song & Fengling Chen. (2019) β-Thujaplicin induces autophagic cell death, apoptosis, and cell cycle arrest through ROS-mediated Akt and p38/ERK MAPK signaling in human hepatocellular carcinoma. Cell Death & Disease 10:4.
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Abudousaimi Aimaiti, Asihaerjiang Maimaitiyiming, Xu Boyong, Kaisaier Aji, Cao Li & Lei Cui. (2017) Low-dose strontium stimulates osteogenesis but high-dose doses cause apoptosis in human adipose-derived stem cells via regulation of the ERK1/2 signaling pathway. Stem Cell Research & Therapy 8:1.
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Ji-Ye Kee, Yo-Han Han, Dae-Seung Kim, Jeong-Geon Mun, Seong-Hwan Park, Hong-Seob So, Sung-Joo Park, Raekil Park, Jae-Young Um & Seung-Heon Hong. (2017) β-Lapachone suppresses the lung metastasis of melanoma via the MAPK signaling pathway. PLOS ONE 12:5, pages e0176937.
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Vitaliy O. KaminskyyBoris Zhivotovsky. (2014) Free Radicals in Cross Talk Between Autophagy and Apoptosis. Antioxidants & Redox Signaling 21:1, pages 86-102.
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Jian-Liang Li, Joseph Mazar, Cuncong Zhong, Geoffrey J. Faulkner, Subramaniam S. Govindarajan, Zhan Zhang, Marcel E. Dinger, Gavin Meredith, Christopher Adams, Shaojie Zhang, John S. Mattick, Animesh Ray & Ranjan J. Perera. (2013) Genome-wide methylated CpG island profiles of melanoma cells reveal a melanoma coregulation network. Scientific Reports 3:1.
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Marisol Godínez-Rubí, Argelia E. Rojas-Mayorquín & Daniel Ortuño-Sahagún. (2013) Nitric Oxide Donors as Neuroprotective Agents after an Ischemic Stroke-Related Inflammatory Reaction. Oxidative Medicine and Cellular Longevity 2013, pages 1-16.
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Đurđica Ignjatović, Danijela Vojnović Milutinović, Aleksandra Nikolić-Kokić, Marija Slavić, Deana Andrić, Mirko Tomić & Slađana Kostić-Rajačić. (2012) The mechanisms responsible for neuroprotective capacity of arylpiperazine dopaminergic ligands against cell death induced by sodium nitroprusside. European Journal of Pharmacology 683:1-3, pages 93-100.
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Yuko Kurokawa, Fumiko Sekiguchi, Satoko Kubo, Yoshiko Yamasaki, Sachi Matsuda, Yukari Okamoto, Teruki Sekimoto, Anna Fukatsu, Hiroyuki Nishikawa, Toshiaki Kume, Nobuyuki Fukushima, Akinori Akaike & Atsufumi Kawabata. (2011) Involvement of ERK in NMDA receptor-independent cortical neurotoxicity of hydrogen sulfide. Biochemical and Biophysical Research Communications 414:4, pages 727-732.
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Luis A. Gomez-Sarosi, Mary Strasberg-Rieber & Manuel Rieber. (2010) H2O2 preferentially synergizes with nitroprusside to induce apoptosis associated with superoxide dismutase dysregulation in human melanoma irrespective of p53 status: Antagonism by o-phenanthroline. Chemico-Biological Interactions 188:1, pages 134-143.
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Maricela Viola Rhenals, Mary Strasberg-Rieber & Manuel Rieber. (2010) Nitric Oxide Donors or Nitrite Counteract Copper-[dithiocarbamate] 2 -Mediated Tumor Cell Death and Inducible Nitric Oxide Synthase Down-Regulation: Possible Role of a Nitrosyl-Copper [Dithiocarbamate] 2 Complex . Journal of Medicinal Chemistry 53:4, pages 1627-1635.
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Sebastien Cagnol & Jean‐Claude Chambard. (2009) ERK and cell death: Mechanisms of ERK‐induced cell death – apoptosis, autophagy and senescence. The FEBS Journal 277:1, pages 2-21.
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