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Research Paper

PRL-3 promotes epithelial mesenchymal transition by regulating cadherin directly

Pages 1352-1359 | Published online: 15 Jul 2009

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Zhenying Ge, Tingxuan Gu, Lingge Zhang, Qingfang Fan, Li Ma & Na Fang. (2022) The phosphatase of regenerating liver-3 protein (PRL-3) promotes glioma cell invasiveness by interacting with β3 –tubulin. Bioengineered 13:2, pages 4112-4121.
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Articles from other publishers (33)

Mingyang Yu, Chunxu Lin & Min Wei. (2023) A pan-cancer analysis of oncogenic protein tyrosine phosphatase subfamily PTP4As. Journal of Holistic Integrative Pharmacy 4:2, pages 185-198.
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Shu-Fen Chen, Hsin-Lun Hsien, Ting-Fang Wang & Ming-Der Lin. (2023) Drosophila Phosphatase of Regenerating Liver Is Critical for Photoreceptor Cell Polarity and Survival during Retinal Development. International Journal of Molecular Sciences 24:14, pages 11501.
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Xiao-Cui Hong, Qi-Lian Liang, Man Chen, Hai-Xia Yang, Jie Huang, Si-Lin Yi, Zhen-Wei Wang, Hai-Yan Liang, Ding-Yue Zhang & Zeng-Yi Huang. (2022) PRL-3 and MMP9 Expression and Epithelial-Mesenchymal Transition Markers in Circulating Tumor Cells From Patients With Colorectal Cancer: Potential Value in Clinical Practice. Frontiers in Oncology 12.
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Heyang Xu, Qiusheng Lan, Yongliang Huang, Yang Zhang, Yujie Zeng, Pengwei Su, Ziqiang Chu, Wei Lai & Zhonghua Chu. (2021) The mechanisms of colorectal cancer cell mesenchymal-epithelial transition induced by hepatocyte exosome-derived miR-203a-3p. BMC Cancer 21:1.
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Miran Rada, Audrey Kapelanski-Lamoureux, Stephanie Petrillo, Sébastien Tabariès, Peter Siegel, Andrew R. Reynolds, Anthoula Lazaris & Peter Metrakos. (2021) Runt related transcription factor-1 plays a central role in vessel co-option of colorectal cancer liver metastases. Communications Biology 4:1.
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Yue Wang, Yubing Guo, Yumeng Hu, Yeqing Sun & Dan Xu. (2020) Endosulfan triggers epithelial-mesenchymal transition via PTP4A3-mediated TGF-β signaling pathway in prostate cancer cells. Science of The Total Environment 731, pages 139234.
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Laura Duciel, Luis Cristobal Monraz Gomez, Maria Kondratova, Inna Kuperstein & Simon Saule. (2019) The Phosphatase PRL-3 Is Involved in Key Steps of Cancer Metastasis. Journal of Molecular Biology 431:17, pages 3056-3067.
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Serge Hardy, Elie Kostantin, Teri Hatzihristidis, Yevgen Zolotarov, Noriko Uetani & Michel L. Tremblay. (2018) Physiological and oncogenic roles of the PRL phosphatases . The FEBS Journal 285:21, pages 3886-3908.
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Heyang Xu, Yongliang Huang, Qiusheng Lan, Yang Zhang, Yujie Zeng, Tao Zhang, Chisheng Chen, Pengwei Su, Ziqiang Chu, Wei Lai & Zhonghua Chu. (2018) The mechanisms of colorectal cancer cell mesenchymal–epithelial transition induced by hepatocyte exosome-derived miR-203a-3p. Journal of Bio-X Research 1:2, pages 62-72.
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Esperanza Martín-Sánchez, Saioa Mendaza, Ane Ulazia-Garmendia, Iñaki Monreal-Santesteban, Alicia Córdoba, Francisco Vicente-García, Idoia Blanco-Luquin, Susana De La Cruz, Ana Aramendia & David Guerrero-Setas. (2017) CDH22 hypermethylation is an independent prognostic biomarker in breast cancer. Clinical Epigenetics 9:1.
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Isabel Radke, Martin Götte, Martin Smollich, Ninette Scharle, Ludwig Kiesel & Pia Wülfing. (2017) Expression of PRL-3 regulates proliferation and invasion of breast cancer cells in vitro. Archives of Gynecology and Obstetrics 296:6, pages 1153-1160.
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Donna Edwards, Krzysztof Moroz, Haitao Zhang, David Mulholland, Asim Abdel-Mageed & Debasis Mondal. (2017) PRL‑3 increases the aggressive phenotype of prostate cancer cells in�vitro and its expression correlates with high-grade prostate tumors in patients. International Journal of Oncology.
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Liying Geng & Jing Wang. (2017) Molecular effectors of radiation resistance in colorectal cancer. Precision Radiation Oncology 1:1, pages 27-33.
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Yongyong Yang, Shenyi Lian, Lin Meng, Like Qu & Chengchao Shou. (2017) Antibody Array Revealed PRL-3 Affects Protein Phosphorylation and Cytokine Secretion. PLOS ONE 12:1, pages e0169665.
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Esten N. Vandsemb, Helena Bertilsson, Pegah Abdollahi, ?ystein St?rkersen, Thea Kristin V?tsveen, Morten Beck Rye, Torstein Baade R?Magne B?rset & Tobias S. Sl?rdahl. (2016) Phosphatase of regenerating liver 3 (PRL-3) is overexpressed in human prostate cancer tissue and promotes growth and migration. Journal of Translational Medicine 14:1.
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Teresa Rubio & Maja Köhn. (2016) Regulatory mechanisms of phosphatase of regenerating liver (PRL)-3. Biochemical Society Transactions 44:5, pages 1305-1312.
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Qian Dong, Xueqiang Ding, Boyang Chang, Haihe Wang & Anxun Wang. (2015) PRL ‐3 promotes migration and invasion and is associated with poor prognosis in salivary adenoid cystic carcinoma . Journal of Oral Pathology & Medicine 45:2, pages 111-118.
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Cheng Xing, Xing-Xing Lu, Peng-Da Guo, Tong Shen, Shen Zhang, Xiao-Shun He, Wen-Juan Gan, Xiu-Ming Li, Jing-Ru Wang, Yuan-Yuan Zhao, Hua Wu & Jian-Ming Li. (2016) Ubiquitin-Specific Protease 4-Mediated Deubiquitination and Stabilization of PRL-3 Is Required for Potentiating Colorectal Oncogenesis. Cancer Research 76:1, pages 83-95.
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Cameron A. Rogers & Catherine J. Pallen. 2016. Protein Tyrosine Phosphatases in Cancer. Protein Tyrosine Phosphatases in Cancer 261 282 .
Hsin-Chih Yeh, Ching-Chia Li, Chun-Nung Huang, Tzyh-Chyuan Hour, Bi-Wen Yeh, Wei-Ming Li, Peir-In Liang, Lin-Li Chang, Chien-Feng Li & Wen-Jeng Wu. (2015) PTP4A3 Independently Predicts Metastasis and Survival in Upper Tract Urothelial Carcinoma Treated with Radical Nephroureterectomy. The Journal of Urology 194:5, pages 1449-1455.
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Anna Pryczynicz, Katarzyna Guzi?ska-Ustymowicz, Katarzyna Niewiarowska, Dariusz Cepowicz & Andrzej Kemona. (2014) PRL-3 and E-cadherin show mutual interactions and participate in lymph node metastasis formation in gastric cancer. Tumor Biology 35:7, pages 6587-6592.
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Xiaofang Xing, Shenyi Lian, Ying Hu, Ziyu Li, Lianhai Zhang, Xianzi Wen, Hong Du, Yongning Jia, Zhixue Zheng, Lin Meng, Chengchao Shou & Jiafu Ji. (2013) Phosphatase of regenerating liver-3 (PRL-3) is associated with metastasis and poor prognosis in gastric carcinoma. Journal of Translational Medicine 11:1.
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Chad D. Walls, Anton Iliuk, Yunpeng Bai, Mu Wang, W. Andy Tao & Zhong-Yin Zhang. (2013) Phosphatase of Regenerating Liver 3 (PRL3) Provokes a Tyrosine Phosphoproteome to Drive Prometastatic Signal Transduction. Molecular & Cellular Proteomics 12:12, pages 3759-3777.
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J Lv, C Liu, H Huang, L Meng, B Jiang, Y Cao, Z Zhou, T She, L Qu, S Wei Song & C Shou. (2013) Suppression of breast tumor growth by DNA vaccination against phosphatase of regenerating liver 3. Gene Therapy 20:8, pages 834-845.
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Wei Lai, Lu Liu, Yujie Zeng, Heng Wu, Heyang Xu, Shuang Chen & Zhonghua Chu. (2013) KCNN4 Channels participate in the EMT induced by PRL-3 in colorectal cancer. Medical Oncology 30:2.
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Pablo Rios, Xun Li & Maja Köhn. (2012) Molecular mechanisms of the PRL phosphatases. The FEBS Journal 280:2, pages 505-524.
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J Zhang, Z Xiao, D Lai, J Sun, C He, Z Chu, H Ye, S Chen & J Wang. (2012) miR-21, miR-17 and miR-19a induced by phosphatase of regenerating liver-3 promote the proliferation and metastasis of colon cancer. British Journal of Cancer 107:2, pages 352-359.
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David P. Labbé, Serge Hardy & Michel L. Tremblay. 2012. Protein Phosphorylation in Health and Disease. Protein Phosphorylation in Health and Disease 253 306 .
Victoria McParland, Giulia Varsano, Xun Li, Janet Thornton, Jancy Baby, Ajay Aravind, Christoph Meyer, Karolina Pavic, Pablo Rios & Maja Köhn. (2011) The Metastasis-Promoting Phosphatase PRL-3 Shows Activity toward Phosphoinositides. Biochemistry 50:35, pages 7579-7590.
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Keishi Yamashita, Shinichi Sakuramoto & Masahiko Watanabe. (2010) Genomic and epigenetic profiles of gastric cancer: Potential diagnostic and therapeutic applications. Surgery Today 41:1, pages 24-38.
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Abdul Qader O. Al-Aidaroos & Qi Zeng. (2010) PRL-3 phosphatase and cancer metastasis. Journal of Cellular Biochemistry 111:5, pages 1087-1098.
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Ping Zheng, Yong-Xia Liu, Lin Chen, Xun-Hua Liu, Zheng-Quan Xiao, Liang Zhao, Guang-Qiu Li, Jun Zhou, Yan-Qing Ding & Jian-Ming Li. (2010) Stathmin, a New Target of PRL-3 Identified by Proteomic Methods, Plays a Key Role in Progression and Metastasis of Colorectal Cancer. Journal of Proteome Research 9:10, pages 4897-4905.
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Akira Ooki, Keishi Yamashita, Shiro Kikuchi, Shinichi Sakuramoto, Natsuya Katada & Masahiko Watanabe. (2010) Phosphatase of regenerating liver-3 as a convergent therapeutic target for lymph node metastasis in esophageal squamous cell carcinoma. International Journal of Cancer 127:3, pages 543-554.
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