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Research Paper

Caveolin-1 regulates VEGF-stimulated angiogenic activities in prostate cancer and endothelial cells

Pages 2284-2294 | Published online: 01 Dec 2009

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Tayfur Cift, Aydogan Mathyk Begum, Berna Aslan Cetin, Hakan Erenel, Abdullah Tuten, Berk Bulut, Nevin Yilmaz, Hakan Ekmekci & Altay Gezer. (2020) Serum caveolin-1 levels in patients with preeclampsia. The Journal of Maternal-Fetal & Neonatal Medicine 33:5, pages 712-717.
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Salahaldin A. Tahir, Shinji Kurosaka, Ryuta Tanimoto, Alexei A. Goltsov, Sanghee Park & Timothy C. Thompson. (2013) Serum caveolin-1, a biomarker of drug response and therapeutic target in prostate cancer models. Cancer Biology & Therapy 14:2, pages 117-126.
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Paul G Corn & Timothy C Thompson. (2010) Identification of a novel prostate cancer biomarker, caveolin-1: Implications and potential clinical benefit. Cancer Management and Research 2, pages 111-122.
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Ying Yu, Xing Huang, Chaoqi Liang & Peng Zhang. (2023) Evodiamine impairs HIF1A histone lactylation to inhibit Sema3A-mediated angiogenesis and PD-L1 by inducing ferroptosis in prostate cancer. European Journal of Pharmacology 957, pages 176007.
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Flavie Courtaut, Alessandra Scagliarini, Virginie Aires, Clarisse Cornebise, Jean-Paul Pais de Barros, Céline Olmiere & Dominique Delmas. (2021) VEGF-R2/Caveolin-1 Pathway of Undifferentiated ARPE-19 Retina Cells: A Potential Target as Anti-VEGF-A Therapy in Wet AMD by Resvega, an Omega-3/Polyphenol Combination. International Journal of Molecular Sciences 22:12, pages 6590.
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Takahiro Iwamiya, Bertrand-David Segard, Yuimi Matsuoka & Tomomi Imamura. (2020) Human cardiac fibroblasts expressing VCAM1 improve heart function in postinfarct heart failure rat models by stimulating lymphangiogenesis. PLOS ONE 15:9, pages e0237810.
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Fatma El-Zahraa Ammar Mohamed, El Zahraa Ibrahim Khalil & Nisreen D. M. Toni. (2019) Caveolin-1 Expression Together with VEGF can be a Predictor for Lung Metastasis and Poor Prognosis in Osteosarcoma. Pathology & Oncology Research 26:3, pages 1787-1795.
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Zeyad D. Nassar & Marie-Odile Parat. (2020) Caveola-forming proteins and prostate cancer. Cancer and Metastasis Reviews 39:2, pages 415-433.
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Dadong Deng, Xihong Tan, Kun Han, Ruimin Ren, Jianhua Cao & Mei Yu. (2020) Transcriptomic and ChIP-seq Integrative Analysis Reveals Important Roles of Epigenetically Regulated lncRNAs in Placental Development in Meishan Pigs. Genes 11:4, pages 397.
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Lu Zhai, Yuhua Liu, Wenpiao Zhao, Qingyun Chen, Tao Guo, Wei Wei, Zhuchun Luo, Yanfeng Huang, Cui Ma, Feng Huang & Xia Dai. (2020) Aerobic and resistance training enhances endothelial progenitor cell function via upregulation of caveolin-1 in mice with type 2 diabetes. Stem Cell Research & Therapy 11:1.
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Katharina Puzik, Veronika Tonnier, Isabell Opper, Antonia Eckert, Lu Zhou, Marie-Claire Kratzer, Ferdinand le Noble, Gerd Ulrich Nienhaus & Dietmar Gradl. (2019) Lef1 regulates caveolin expression and caveolin dependent endocytosis, a process necessary for Wnt5a/Ror2 signaling during Xenopus gastrulation. Scientific Reports 9:1.
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Rebecca Lee, Nicoletta Del Papa, Martin Introna, Charles F Reese, Marina Zemskova, Michael Bonner, Gustavo Carmen-Lopez, Kristi Helke, Stanley Hoffman & Elena Tourkina. (2019) Adipose-derived mesenchymal stromal/stem cells in systemic sclerosis: Alterations in function and beneficial effect on lung fibrosis are regulated by caveolin-1. Journal of Scleroderma and Related Disorders 4:2, pages 127-136.
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John E McDonough, Naftali Kaminski, Bernard Thienpont, James C Hogg, Bart M Vanaudenaerde & Wim A Wuyts. (2019) Gene correlation network analysis to identify regulatory factors in idiopathic pulmonary fibrosis. Thorax 74:2, pages 132-140.
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Esmeralda K. Bosma, Cornelis J. F. van Noorden, Reinier O. Schlingemann & Ingeborg Klaassen. (2018) The role of plasmalemma vesicle-associated protein in pathological breakdown of blood–brain and blood–retinal barriers: potential novel therapeutic target for cerebral edema and diabetic macular edema. Fluids and Barriers of the CNS 15:1.
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Shanshan Wang & Brian P. Head. (2018) Caveolin-1 in Stroke Neuropathology and Neuroprotection: A Novel Molecular Therapeutic Target for Ischemic-Related Injury. Current Vascular Pharmacology 17:1, pages 41-49.
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Vinoth Prasanna Gunasekaran, Kumari Nishi, Dakshinamurthy Sivakumar, Thirunavukkarasu Sivaraman & Ganeshan Mathan. (2018) Identification of 2,4-dihydroxy-5-pyrimidinyl imidothiocarbomate as a novel inhibitor to Y box binding protein-1 (YB-1) and its therapeutic actions against breast cancer. European Journal of Pharmaceutical Sciences 116, pages 2-14.
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Fengxia Tu, Qiongyi Pang, Xiang Chen, Tingting Huang, Meixia Liu & Qiongxiang Zhai. (2017) Angiogenic effects of apigenin on endothelial cells after hypoxia-reoxygenation via the caveolin-1 pathway. International Journal of Molecular Medicine.
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Shalini Gross, Kavi Devraj, Yuxi Feng, Jadranka Macas, Stefan Liebner & Thomas Wieland. (2016) Nucleoside diphosphate kinase B regulates angiogenic responses in the endothelium via caveolae formation and c-Src-mediated caveolin-1 phosphorylation. Journal of Cerebral Blood Flow & Metabolism 37:7, pages 2471-2484.
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Qiongyi Pang, Huimei Zhang, Zhenzhen Chen, Yudan Wu, Min Bai, Yidian Liu, Yun Zhao, Fengxia Tu, Chan Liu & Xiang Chen. (2017) Role of caveolin-1/vascular endothelial growth factor pathway in basic fibroblast growth factor-induced angiogenesis and neurogenesis after treadmill training following focal cerebral ischemia in rats. Brain Research 1663, pages 9-19.
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Dorea Pleasant-Jenkins, Charles Reese, Panneerselvem Chinnakkannu, Harinath Kasiganesan, Elena Tourkina, Stanley Hoffman & Dhandapani Kuppuswamy. (2017) Reversal of maladaptive fibrosis and compromised ventricular function in the pressure overloaded heart by a caveolin-1 surrogate peptide. Laboratory Investigation 97:4, pages 370-382.
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Kim Cuc Thi NguyenKyung A Cho. (2017) Versatile Functions of Caveolin-1 in Aging-related Diseases. Chonnam Medical Journal 53:1, pages 28.
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Miriam Stenzel, Aysegül Tura, Khaled Nassar, Jens Martin Rohrbach, Salvatore Grisanti, Matthias Lüke & Julia Lüke. (2016) Analysis of caveolin-1 and phosphoinositol-3 kinase expression in primary uveal melanomas. Clinical & Experimental Ophthalmology 44:5, pages 400-409.
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Luis F. de Castro, Marta Maycas, Beatriz Bravo, Pedro Esbrit & Arancha Gortazar. (2015) VEGF Receptor 2 (VEGFR2) Activation Is Essential for Osteocyte Survival Induced by Mechanotransduction. Journal of Cellular Physiology 230:2, pages 278-285.
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Luke H. Hoeppner, Sutapa Sinha, Ying Wang, Resham Bhattacharya, Shamit Dutta, Xun Gong, Victoria M. Bedell, Sandip Suresh, Chang zoon Chun, Ramani Ramchandran, Stephen C. Ekker & Debabrata Mukhopadhyay. (2015) RhoC maintains vascular homeostasis by regulating VEGF-induced signaling in endothelial cells. Journal of Cell Science.
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Tao Shan, Hongwei Lu, Hong Ji, Yiming Li, Jian Guo, Xi Chen & Tao Wu. (2014) Loss of Stromal Caveolin-1 Expression: A Novel Tumor Microenvironment Biomarker That Can Predict Poor Clinical Outcomes for Pancreatic Cancer. PLoS ONE 9:6, pages e97239.
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Hyeongsun Moon, Michelle M. Hill, Matthew J. Roberts, Robert A. Gardiner & Andrew J. Brown. (2014) Statins: protectors or pretenders in prostate cancer?. Trends in Endocrinology & Metabolism 25:4, pages 188-196.
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Zeyad D. Nassar, Michelle M. Hill, Robert G. Parton & Marie-Odile Parat. (2013) Caveola-forming proteins caveolin-1 and PTRF in prostate cancer. Nature Reviews Urology 10:9, pages 529-536.
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Anastasia Chillà, Francesca Magherini, Francesca Margheri, Anna Laurenzana, Tania Gamberi, Luca Bini, Laura Bianchi, Giovanna Danza, Benedetta Mazzanti, Simona Serratì, Alessandra Modesti, Mario Del Rosso & Gabriella Fibbi. (2013) Proteomic Identification of VEGF-dependent Protein Enrichment to Membrane Caveolar-raft Microdomains in Endothelial Progenitor Cells. Molecular & Cellular Proteomics 12:7, pages 1926-1938.
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Fabia Pancotti, Laura Roncuzzi, Marcello Maggiolini & Anna Gasperi-Campani. (2012) Caveolin-1 silencing arrests the proliferation of metastatic lung cancer cells through the inhibition of STAT3 signaling. Cellular Signalling 24:7, pages 1390-1397.
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