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Research Paper

Induction of in vivo synthetic lethal RNAi responses to treat glioblastoma

Pages 2304-2311 | Published online: 01 Dec 2009

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Kimia Kardani, Alireza Milani, Samaneh H. Shabani & Azam Bolhassani. (2019) Cell penetrating peptides: the potent multi-cargo intracellular carriers. Expert Opinion on Drug Delivery 16:11, pages 1227-1258.
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Apollo D. Kacsinta & Steven F. Dowdy. (2016) Current views on inducing synthetic lethal RNAi responses in the treatment of cancer. Expert Opinion on Biological Therapy 16:2, pages 161-172.
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Khaled Messaoudi, Patrick Saulnier, Kim Boesen, Jean-Pierre Benoit & Frederic Lagarce. (2014) Anti-epidermal growth factor receptor siRNA carried by chitosan-transacylated lipid nanocapsules increases sensitivity of glioblastoma cells to temozolomide. International Journal of Nanomedicine 9, pages 1479-1490.
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Taavi Lehto, Kaido Kurrikoff & Ülo Langel. (2012) Cell-penetrating peptides for the delivery of nucleic acids. Expert Opinion on Drug Delivery 9:7, pages 823-836.
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Qingqing Zhang, Nanxin Liu, Jin Wang, Yuying Liu, Kai Wang, Jie Zhang & Xiaoyan Pan. (2023) The Recent Advance of Cell-Penetrating and Tumor-Targeting Peptides as Drug Delivery Systems Based on Tumor Microenvironment. Molecular Pharmaceutics 20:2, pages 789-809.
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Yuan Rui, Gabriella Quiñones & Jordan J. Green. (2017) Biodegradable and bioreducible poly(beta-amino ester) nanoparticles for intracellular delivery to treat brain cancer. AIChE Journal 63:5, pages 1470-1482.
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Giulia Guidotti, Liliana Brambilla & Daniela Rossi. (2017) Cell-Penetrating Peptides: From Basic Research to Clinics. Trends in Pharmacological Sciences 38:4, pages 406-424.
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Weili Ma & Won H. Suh. 2017. Control of Amphiphile Self-Assembling at the Molecular Level: Supra-Molecular Assemblies with Tuned Physicochemical Properties for Delivery Applications. Control of Amphiphile Self-Assembling at the Molecular Level: Supra-Molecular Assemblies with Tuned Physicochemical Properties for Delivery Applications 297 319 .
Taavi Lehto, Kariem Ezzat, Matthew J.A. Wood & Samir EL Andaloussi. (2016) Peptides for nucleic acid delivery. Advanced Drug Delivery Reviews 106, pages 172-182.
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Ana Dinca, Wei-Ming Chien & Michael Chin. (2016) Intracellular Delivery of Proteins with Cell-Penetrating Peptides for Therapeutic Uses in Human Disease. International Journal of Molecular Sciences 17:2, pages 263.
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Dana C Danielson, Natalie Sachrajda, Wei Wang, Roxana Filip & John Paul Pezacki. (2016) A Novel p19 Fusion Protein as a Delivery Agent for Short-interfering RNAs. Molecular Therapy - Nucleic Acids 5, pages e303.
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Thomas C. Roberts, Kariem Ezzat, Samir EL Andaloussi & Marc S. Weinberg. 2016. SiRNA Delivery Methods. SiRNA Delivery Methods 291 310 .
Yoshiya Iguchi, Hiroyuki Michiue, Mizuki Kitamatsu, Yuri Hayashi, Fumiaki Takenaka, Tei-ichi Nishiki & Hideki Matsui. (2015) Tumor-specific delivery of BSH-3R for boron neutron capture therapy and positron emission tomography imaging in a mouse brain tumor model. Biomaterials 56, pages 10-17.
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Prisca Boisguérin, Sébastien Deshayes, Michael J. Gait, Liz O'Donovan, Caroline Godfrey, Corinne A. Betts, Matthew J.A. Wood & Bernard Lebleu. (2015) Delivery of therapeutic oligonucleotides with cell penetrating peptides. Advanced Drug Delivery Reviews 87, pages 52-67.
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Kristen M. Turner, Youting Sun, Ping Ji, Kirsi J. Granberg, Brady Bernard, Limei Hu, David E. Cogdell, Xinhui Zhou, Olli Yli-Harja, Matti Nykter, Ilya Shmulevich, W. K. Alfred YungGregory N. Fuller & Wei Zhang. (2015) Genomically amplified Akt3 activates DNA repair pathway and promotes glioma progression. Proceedings of the National Academy of Sciences 112:11, pages 3421-3426.
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Meenakshi Malhotra, André Toulouse, Bruno M. D. C. Godinho, David John Mc Carthy, John F. Cryan & Caitriona M. O'Driscoll. (2015) RNAi therapeutics for brain cancer: current advancements in RNAi delivery strategies. Molecular BioSystems 11:10, pages 2635-2657.
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X. X. Yang, X. N. Hou, B. Xu, X. Hao, G. J. Jiang & T. J. Fan. (2014) Cell-penetrating peptide delivery of biologically active oct4 protein into cultured Takifugu rubripes spermary cells . Journal of Fish Biology 85:5, pages 1369-1380.
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Nanako Ookubo, Hiroyuki Michiue, Mizuki Kitamatsu, Maho Kamamura, Tei-ichi Nishiki, Iori Ohmori & Hideki Matsui. (2014) The transdermal inhibition of melanogenesis by a cell-membrane-permeable peptide delivery system based on poly-arginine. Biomaterials 35:15, pages 4508-4516.
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Benjamin M Luby, Arash Farhadi, Mojdeh Shakiba, Danielle M Charron, Áron Roxin & Gang Zheng. (2014) Research Highlights: Highlights from the latest articles in nanomedicine. Nanomedicine 9:4, pages 385-388.
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Paul Diehl, Donato Tedesco & Alex Chenchik. (2014) Use of RNAi screens to uncover resistance mechanisms in cancer cells and identify synthetic lethal interactions. Drug Discovery Today: Technologies 11, pages 11-18.
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Hiroyuki Michiue, Yoshinori Sakurai, Natsuko Kondo, Mizuki Kitamatsu, Feng Bin, Kiichiro Nakajima, Yuki Hirota, Shinji Kawabata, Tei-ichi Nishiki, Iori Ohmori, Kazuhito Tomizawa, Shin-ichi Miyatake, Koji Ono & Hideki Matsui. (2014) The acceleration of boron neutron capture therapy using multi-linked mercaptoundecahydrododecaborate (BSH) fused cell-penetrating peptide. Biomaterials 35:10, pages 3396-3405.
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Meong Cheol Shin, Jian Zhang, Kyoung Ah Min, Kyuri Lee, Youngro Byun, Allan E. David, Huining He & Victor C. Yang. (2014) Cell-penetrating peptides: Achievements and challenges in application for cancer treatment. Journal of Biomedical Materials Research Part A 102:2, pages 575-587.
Crossref
Lisa Gherardini, Giuseppe Bardi, Mariangela Gennaro & Tommaso Pizzorusso. (2013) Novel siRNA delivery strategy: a new “strand” in CNS translational medicine?. Cellular and Molecular Life Sciences 71:1, pages 1-20.
Crossref
Kazunori Watanabe & Takashi Ohtsuki. 2014. Intracellular Delivery II. Intracellular Delivery II 403 416 .
Ewa Szczurek, Navodit Misra & Martin Vingron. (2013) Synthetic sickness or lethality points at candidate combination therapy targets in glioblastoma. International Journal of Cancer 133:9, pages 2123-2132.
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Pauline Resnier, Stephanie David, Nolwenn Lautram, Gaëtan J.-R. Delcroix, Anne Clavreul, Jean-Pierre Benoit & Catherine Passirani. (2013) EGFR siRNA lipid nanocapsules efficiently transfect glioma cells in vitro. International Journal of Pharmaceutics 454:2, pages 748-755.
Crossref
Sandesh Subramanya & Lance Ford. 2013. Advanced Delivery and Therapeutic Applications of RNAi. Advanced Delivery and Therapeutic Applications of RNAi 45 62 .
Caroline Palm-Apergi & Steven Dowdy. 2013. Nanotechnology for the Delivery of Therapeutic Nucleic Acids. Nanotechnology for the Delivery of Therapeutic Nucleic Acids 93 106 .
Ikuhiko Nakase, Gen Tanaka & Shiroh Futaki. (2013) Cell-penetrating peptides (CPPs) as a vector for the delivery of siRNAs into cells. Molecular BioSystems 9:5, pages 855.
Crossref
Thibault CoursindelPeter JärverMichael J. Gait. (2012) Peptide-Based In Vivo Delivery Agents for Oligonucleotides and siRNA . Nucleic Acid Therapeutics 22:2, pages 71-76.
Crossref
Garrett R Rettig & Mark A Behlke. (2012) Progress Toward In Vivo Use of siRNAs-II. Molecular Therapy 20:3, pages 483-512.
Crossref
Peter Järver, Thibault Coursindel, Samir EL Andaloussi, Caroline Godfrey, Matthew JA Wood & Michael J Gait. (2012) Peptide-mediated Cell and In Vivo Delivery of Antisense Oligonucleotides and siRNA. Molecular Therapy - Nucleic Acids 1, pages e27.
Crossref
Arjen van den Berg & Steven F Dowdy. (2011) Protein transduction domain delivery of therapeutic macromolecules. Current Opinion in Biotechnology 22:6, pages 888-893.
Crossref
Kaido Kurrikoff, Julia Suhorut & ülo Langel. 2011. Drug Delivery in Oncology. Drug Delivery in Oncology 1187 1217 .
S Dharmapuri, D Peruzzi, E Marra, F Palombo, A J Bett, S R Bartz, M Yong, G Ciliberto, N La Monica, C A Buser, C Toniatti & L Aurisicchio. (2011) Intratumor RNA interference of cell cycle genes slows down tumor progression. Gene Therapy 18:7, pages 727-733.
Crossref
Raelene Endersby, Xiaoyan Zhu, Nissim Hay, David W. Ellison & Suzanne J. Baker. (2011) Nonredundant Functions for Akt Isoforms in Astrocyte Growth and Gliomagenesis in an Orthotopic Transplantation Model. Cancer Research 71:12, pages 4106-4116.
Crossref
Samir EL Andaloussi, Taavi Lehto, Imre Mäger, Katri Rosenthal-Aizman, Iulian I. Oprea, Oscar E. Simonson, Helena Sork, Kariem Ezzat, Dana M. Copolovici, Kaido Kurrikoff, Joana R. Viola, Eman M. Zaghloul, Rannar Sillard, Henrik J. Johansson, Fatouma Said Hassane, Peter Guterstam, Julia Suhorutšenko, Pedro M. D. Moreno, Nikita Oskolkov, Jonas Hälldin, Ulf Tedebark, Andres Metspalu, Bernard Lebleu, Janne Lehtiö, C. I. Edvard Smith & Ülo Langel. (2011) Design of a peptide-based vector, PepFect6, for efficient delivery of siRNA in cell culture and systemically in vivo. Nucleic Acids Research 39:9, pages 3972-3987.
Crossref
Robyn P. Hickerson, Manuel A. Flores, Devin Leake, Maria F. Lara, Christopher H. Contag, Sancy A. Leachman & Roger L. Kaspar. (2011) Use of Self-Delivery siRNAs to Inhibit Gene Expression in an Organotypic Pachyonychia Congenita Model. Journal of Investigative Dermatology 131:5, pages 1037-1044.
Crossref
Wouter P.R. Verdurmen & Roland Brock. (2011) Biological responses towards cationic peptides and drug carriers. Trends in Pharmacological Sciences 32:2, pages 116-124.
Crossref
Aliasger K. Salem & Mark A. Behlke. 2011. RNA Interference. RNA Interference 174 215 .
Staffan Lindberg, Dana M Copolovici & Ülo Langel. (2011) Therapeutic delivery opportunities, obstacles and applications for cell-penetrating peptides. Therapeutic Delivery 2:1, pages 71-82.
Crossref
Taavi Lehto, Kariem Ezzat & Ülo Langel. 2011. Nanoparticles in Translational Science and Medicine. Nanoparticles in Translational Science and Medicine 397 426 .
Shinji Mizuarai & Hidehito Kotani. (2010) Synthetic lethal interactions for the development of cancer therapeutics: biological and methodological advancements. Human Genetics 128:6, pages 567-575.
Crossref
Peter Järver, Imre Mäger & Ülo Langel. (2010) In vivo biodistribution and efficacy of peptide mediated delivery. Trends in Pharmacological Sciences 31:11, pages 528-535.
Crossref