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Research Paper

Sorafenib inhibits ERK1/2 and MCL-1L phosphorylation levels resulting in caspase-independent cell death in malignant pleural mesothelioma

Pages 2406-2416 | Published online: 15 Dec 2009

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Marie D. Ralff & Wafik S. El-Deiry. (2018) TRAIL pathway targeting therapeutics. Expert Review of Precision Medicine and Drug Development 3:3, pages 197-204.
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Giovanni Luca Ceresoli & Paolo Andrea Zucali. (2012) Anti-angiogenic therapies for malignant pleural mesothelioma. Expert Opinion on Investigational Drugs 21:6, pages 833-844.
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Fernanda Antunes, Gustavo J. S. Pereira, Renata F. Saito, Marcus V. Buri, Mara Gagliardi, Claudia Bincoletto, Roger Chammas, Gian Maria Fimia, Mauro Piacentini, Marco Corazzari & Soraya Soubhi Smaili. (2020) Effective Synergy of Sorafenib and Nutrient Shortage in Inducing Melanoma Cell Death through Energy Stress. Cells 9:3, pages 640.
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Vasiliki Galani, Anna Varouktsi, Stamatis S. Papadatos, Antigoni Mitselou, Ioannis Sainis, Stavros Constantopoulos & Yotanna Dalavanga. (2019) The role of apoptosis defects in malignant mesothelioma pathogenesis with an impact on prognosis and treatment. Cancer Chemotherapy and Pharmacology 84:2, pages 241-253.
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Leticia Serrano-Oviedo, Marta Ortega-Muelas, Jesús García-Cano, María Ll. Valero, Francisco J. Cimas, Raquel Pascual-Serra, Diego M. Fernandez-Aroca, Olga Roche, María J. Ruiz-Hidalgo, Borja Belandia, José M. Giménez-Bachs, Antonio S. Salinas & Ricardo Sanchez-Prieto. (2018) Autophagic cell death associated to Sorafenib in renal cell carcinoma is mediated through Akt inhibition in an ERK1/2 independent fashion. PLOS ONE 13:7, pages e0200878.
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Shilan Ding, Min Wang, Song Fang, Huibo Xu, Huiting Fan, Yu Tian, Yadong Zhai, Shan Lu, Xin Qi, Fei Wei, Guibo Sun & Xiaobo Sun. (2018) D-dencichine Regulates Thrombopoiesis by Promoting Megakaryocyte Adhesion, Migration and Proplatelet Formation. Frontiers in Pharmacology 9.
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Zhaoxia Zou, Yufang Yin, Jenny Lin, Li-chen J. Hsu, Vanessa L. Brandon, Fan Yang, Richard Jove, Rahul Jandial, Gang Li & Mike Y. Chen. (2016) Convection-enhanced delivery of sorafenib and suppression of tumor progression in a murine model of brain melanoma through the inhibition of signal transducer and activator of transcription 3. Journal of Neurosurgery 124:5, pages 1310-1318.
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Aaron T. Wecksler, Sung Hee Hwang, Jun-Yan Liu, Hiromi I. Wettersten, Christophe Morisseau, Jian Wu, Robert H. Weiss & Bruce D. Hammock. (2014) Biological evaluation of a novel sorafenib analogue, t-CUPM. Cancer Chemotherapy and Pharmacology 75:1, pages 161-171.
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Susann Voigt, Stephan Philipp, Parvin Davarnia, Supandi Winoto-Morbach, Christian Röder, Christoph Arenz, Anna Trauzold, Dieter Kabelitz, Stefan Schütze, Holger Kalthoff & Dieter Adam. (2014) TRAIL-induced programmed necrosis as a novel approach to eliminate tumor cells. BMC Cancer 14:1.
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Gordan Srkalovic, Mohamad A. Hussein, Antje Hoering, Jeffrey A. Zonder, Leslie L. Popplewell, Harsha Trivedi, Sandy Mazzoni, Rachel Sexton, Robert Z. Orlowski & Bart Barlogie. (2014) A phase II trial of BAY 43‐9006 (sorafenib) ( NSC ‐724772) in patients with relapsing and resistant multiple myeloma: SWOG S0434 . Cancer Medicine 3:5, pages 1275-1283.
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Scott J Dixon, Darpan N Patel, Matthew Welsch, Rachid Skouta, Eric D Lee, Miki Hayano, Ajit G Thomas, Caroline E Gleason, Nicholas P Tatonetti, Barbara S Slusher & Brent R Stockwell. (2014) Pharmacological inhibition of cystine–glutamate exchange induces endoplasmic reticulum stress and ferroptosis. eLife 3.
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Vladimir Lazar, Nathalie Lassau, Guillaume Meurice, Yohann Loriot, Carol Peña, Christophe Massard, Caroline Robert, Thomas Robert, Marie-Aude Le Berre, Thierry de Baere, Philippe Dessen, Jean-Charles Soria & Jean-Pierre Armand. (2013) Sorafenib plus dacarbazine in solid tumors: a phase I study with dynamic contrast-enhanced ultrasonography and genomic analysis of sequential tumor biopsy samples. Investigational New Drugs 32:2, pages 312-322.
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Laurence A. Booth, Seyedmehrad Tavallai, Hossein A. Hamed, Nichola Cruickshanks & Paul Dent. (2014) The role of cell signalling in the crosstalk between autophagy and apoptosis. Cellular Signalling 26:3, pages 549-555.
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J Wan, T Liu, L Mei, J Li, K Gong, C Yu & W Li. (2013) Synergistic antitumour activity of sorafenib in combination with tetrandrine is mediated by reactive oxygen species (ROS)/Akt signaling. British Journal of Cancer 109:2, pages 342-350.
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Sarah Shirley & Olivier Micheau. (2013) Targeting c-FLIP in cancer. Cancer Letters 332:2, pages 141-150.
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R Wang, L Xia, J Gabrilove, S Waxman & Y Jing. (2012) Downregulation of Mcl-1 through GSK-3β activation contributes to arsenic trioxide-induced apoptosis in acute myeloid leukemia cells. Leukemia 27:2, pages 315-324.
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Roberto E Favoni, Antonio Daga, Paolo Malatesta & Tullio Florio. (2012) Preclinical studies identify novel targeted pharmacological strategies for treatment of human malignant pleural mesothelioma. British Journal of Pharmacology 166:2, pages 532-553.
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Vibeke Hervik Bull, Krishnaraj Rajalingam & Bernd Thiede. (2012) Sorafenib-Induced Mitochondrial Complex I Inactivation and Cell Death in Human Neuroblastoma Cells. Journal of Proteome Research 11:3, pages 1609-1620.
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Didier Jean, Julien Daubriac, Françoise Le Pimpec-Barthes, Françoise Galateau-Salle & Marie-Claude Jaurand. (2012) Molecular Changes in Mesothelioma With an Impact on Prognosis and Treatment. Archives of Pathology & Laboratory Medicine 136:3, pages 277-293.
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Roberto E. Favoni & Tullio Florio. (2011) Combined chemotherapy with cytotoxic and targeted compounds for the management of human malignant pleural mesothelioma. Trends in Pharmacological Sciences 32:8, pages 463-479.
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Ahmad R. Safa & Karen E. Pollok. (2011) Targeting the Anti-Apoptotic Protein c-FLIP for Cancer Therapy. Cancers 3:2, pages 1639-1671.
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