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Research Paper

Therapeutic potential of various β-glucan sources in conjunction with anti-tumor monoclonal antibody in cancer therapy

Pages 218-225 | Published online: 01 Feb 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (5)

Marcus Schmidt. (2022) Cereal beta-glucans: an underutilized health endorsing food ingredient. Critical Reviews in Food Science and Nutrition 62:12, pages 3281-3300.
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Olivier Fortin, Blanca R. Aguilar-Uscanga, Khanh D. Vu, Stephane Salmieri & Monique Lacroix. (2018) Effect of Saccharomyces Boulardii Cell Wall Extracts on Colon Cancer Prevention in Male F344 Rats Treated with 1,2-Dimethylhydrazine. Nutrition and Cancer 70:4, pages 632-642.
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Sun Hee Kang, Hye Ryun Kim, Jae Ho Kim, Byung Hak Ahn, Tae Wan Kim & Jang-Eun Kim. (2014) Identification of Wild Yeast Strains and Analysis of Their β-Glucan and Glutathione Levels for Use in Makgeolli Brewing. Mycobiology 42:4, pages 361-367.
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Catherine Ulbricht. (2014) An Evidence-Based Systematic Review of Beta-Glucan by the Natural Standard Research Collaboration. Journal of Dietary Supplements 11:4, pages 361-475.
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Shawn M. Talbott & Julie A. Talbott. (2012) Baker's Yeast Beta-Glucan Supplement Reduces Upper Respiratory Symptoms and Improves Mood State in Stressed Women. Journal of the American College of Nutrition 31:4, pages 295-300.
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Articles from other publishers (45)

Qing-Qing Dong, Qian Wu, Yi Lu, Yi Shi, Ke-Da Yang, Xiao-Ling Xu & Wei Chen. (2023) Exploring β-glucan as a micro-nano system for oral delivery targeted the colon. International Journal of Biological Macromolecules 253, pages 127360.
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Xi Huang, Si Li, Rong Ding, Yuan Li, Canlin Li & Rui Gu. (2023) Antitumor effects of polysaccharides from medicinal lower plants: A review. International Journal of Biological Macromolecules 252, pages 126313.
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Emma J. Murphy, Emanuele Rezoagli, Catherine Collins, Sushanta Kumar Saha, Ian Major & Patrick Murray. (2023) Sustainable production and pharmaceutical applications of β-glucan from microbial sources. Microbiological Research 274, pages 127424.
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Hossein Mehralizadeh, Ahmad Nazari, Farshid Oruji, Minoo Roostaie, Ghazaleh Hosseininozari, Omid Yazdani, Romina Esbati & Kamran Roudini. (2023) Cytokine sustained delivery for cancer therapy; special focus on stem cell- and biomaterial- based delivery methods. Pathology - Research and Practice 247, pages 154528.
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Ravindra Pal Singh & Aditi Bhardwaj. (2023) β-glucans: a potential source for maintaining gut microbiota and the immune system. Frontiers in Nutrition 10.
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Xin Hu, Yifang Shui, Hiroshi Hirano, Kisato Kusano, Wen-Zhi Guo, Masayuki Fujino & Xiao-Kang Li. (2022) PD-L1 antibody enhanced β-glucan antitumor effects via blockade of the immune checkpoints in a melanoma model. Cancer Immunology, Immunotherapy 72:3, pages 719-731.
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Shiu-Nan Chen, Fan-Hua Nan, Ming-Wei Liu, Min-Feng Yang, Ya-Chih Chang & Sherwin Chen. (2023) Evaluation of Immune Modulation by β-1,3; 1,6 D-Glucan Derived from Ganoderma lucidum in Healthy Adult Volunteers, A Randomized Controlled Trial. Foods 12:3, pages 659.
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Amin Abbasi, Tina Rahbar Saadat & Yalda Rahbar Saadat. (2022) Microbial exopolysaccharides–β-glucans–as promising postbiotic candidates in vaccine adjuvants. International Journal of Biological Macromolecules 223, pages 346-361.
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Pratsanee Hiengrach, Peerapat Visitchanakun, Malcolm A. Finkelman, Wiwat Chancharoenthana & Asada Leelahavanichkul. (2022) More Prominent Inflammatory Response to Pachyman than to Whole-Glucan Particle and Oat-β-Glucans in Dextran Sulfate-Induced Mucositis Mice and Mouse Injection through Proinflammatory Macrophages. International Journal of Molecular Sciences 23:7, pages 4026.
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Yazhuo Zhang, Xinning Liu, Jun Zhao, Jie Wang, Qiaoling Song & Chenyang Zhao. (2022) The phagocytic receptors of β-glucan. International Journal of Biological Macromolecules 205, pages 430-441.
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Emma J. Murphy, Emanuele Rezoagli, Robert Pogue, Bianca Simonassi-Paiva, Ismin Izwani Zainol Abidin, Gustavo Waltzer Fehrenbach, Emer O'Neil, Ian Major, John G. Laffey & Neil Rowan. (2022) Immunomodulatory activity of β-glucan polysaccharides isolated from different species of mushroom – A potential treatment for inflammatory lung conditions. Science of The Total Environment 809, pages 152177.
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Jean A. Boutros, Andrew S. Magee & Donald Cox. (2022) Comparison of structural differences between yeast β-glucan sourced from different strains of saccharomyces cerevisiae and processed using proprietary manufacturing processes. Food Chemistry 367, pages 130708.
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Swantje Fischer, Felix Stegmann, Vinayaga Srinivasan Gnanapragassam & Bernd Lepenies. (2022) From structure to function – Ligand recognition by myeloid C-type lectin receptors. Computational and Structural Biotechnology Journal 20, pages 5790-5812.
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S.N. Chen, C.S. Chang, M.F. Yang, S. Chen, M. Soni & B. Mahadevan. (2022) Subchronic toxicity and genotoxicity studies of Hericium erinaceus β-glucan extract preparation. Current Research in Toxicology 3, pages 100068.
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Peyman Abdeshahian, Jesús Jiménez Ascencio, Rafael R. Philippini, Felipe Antonio Fernandes Antunes, Andre S. de Carvalho, Mojgan Abdeshahian, Júlio César dos Santos & Silvio Silvério da Silva. (2020) Valorization of Lignocellulosic Biomass and Agri-food Processing Wastes for Production of Glucan Polymer. Waste and Biomass Valorization 12:6, pages 2915-2931.
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Anna Jéssica Duarte Silva, Larissa Silva de Macêdo, Lígia Rosa Sales Leal, André Luiz Santos de Jesus & Antonio Carlos Freitas. (2021) Yeasts as a promising delivery platform for DNA and RNA vaccines. FEMS Yeast Research 21:3.
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Vaclav Vetvicka, Tamara V. Teplyakova, Alexandra B. Shintyapina & Tatiana A. Korolenko. (2021) Effects of Medicinal Fungi-Derived β-Glucan on Tumor Progression. Journal of Fungi 7:4, pages 250.
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Shao-Hsiang Liu, Po-Sheng Chen, Chun-Chieh Huang, Yi-Tu Hung, Mei-Ying Lee, Wei-Hung Lin, Yuan-Chuan Lin & Alan Yueh-Luen Lee. (2021) Unlocking the Mystery of the Therapeutic Effects of Chinese Medicine on Cancer. Frontiers in Pharmacology 11.
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Tim Ebbecke, Christina Diersing, Dimitri L. Lindenwald, Felix Stegmann & Bernd Lepenies. 2021. Comprehensive Glycoscience. Comprehensive Glycoscience 185 214 .
Roshanak Sambrani, Jalal Abdolalizadeh, Leila Kohan & Behboud Jafari. (2021) Recent advances in the application of probiotic yeasts, particularly Saccharomyces, as an adjuvant therapy in the management of cancer with focus on colorectal cancer. Molecular Biology Reports 48:1, pages 951-960.
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Elena De Marco Castro, Philip C. Calder & Helen M. Roche. (2020) β‐1,3/1,6‐Glucans and Immunity: State of the Art and Future Directions. Molecular Nutrition & Food Research 65:1, pages 1901071.
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Emma J. Murphy, Emanuele Rezoagli, Ian Major, Neil J. Rowan & John G. Laffey. (2020) β-Glucan Metabolic and Immunomodulatory Properties and Potential for Clinical Application. Journal of Fungi 6:4, pages 356.
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Guillaume Déjean, Kazune Tamura, Adriana Cabrera, Namrata Jain, Nicholas A. Pudlo, Gabriel Pereira, Alexander Holm Viborg, Filip Van Petegem, Eric C. Martens & Harry Brumer. (2020) Synergy between Cell Surface Glycosidases and Glycan-Binding Proteins Dictates the Utilization of Specific Beta(1,3)-Glucans by Human Gut Bacteroides . mBio 11:2.
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Nikolina Markovina, Ines Banjari, Viljemka Bucevic Popovic, Antonia Jelicic Kadic & Livia Puljak. (2020) Efficacy and safety of oral and inhalation commercial beta-glucan products: Systematic review of randomized controlled trials. Clinical Nutrition 39:1, pages 40-48.
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Muthukumaran Jayachandran, Jiali Chen, Stephen Sum Man Chung & Baojun Xu. (2018) A critical review on the impacts of β-glucans on gut microbiota and human health. The Journal of Nutritional Biochemistry 61, pages 101-110.
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Yiming Jin, Pingli Li & Fengshan Wang. (2018) β-glucans as potential immunoadjuvants: A review on the adjuvanticity, structure-activity relationship and receptor recognition properties. Vaccine 36:35, pages 5235-5244.
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Mark Joseph Desamero, Shigeru Kakuta, James Kenn Chambers, Kazuyuki Uchida, Satoshi Hachimura, Masaya Takamoto, Jun Nakayama, Hiroyuki Nakayama & Shigeru Kyuwa. (2018) Orally administered brown seaweed-derived β-glucan effectively restrained development of gastric dysplasia in A4gnt KO mice that spontaneously develop gastric adenocarcinoma. International Immunopharmacology 60, pages 211-220.
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S.N. Chen, C.S. Chang, S. Chen & Madhu Soni. (2017) Subchronic toxicity and genotoxicity studies of Antrodia mushroom β-glucan preparation. Regulatory Toxicology and Pharmacology.
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Raheleh Roudi, Shahla Roudbar Mohammadi, Maryam Roudbary & Monireh Mohsenzadegan. (2017) Lung cancer and β-glucans: review of potential therapeutic applications. Investigational New Drugs 35:4, pages 509-517.
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Monice M. Fiume, Bart Heldreth, Wilma F. Bergfeld, Donald V. Belsito, Ronald A. Hill, Curtis D. Klaassen, Daniel C. Liebler, James G. MarksJrJr, Ronald C. Shank, Thomas J. Slaga, Paul W. Snyder & F. Alan Andersen. (2016) Safety Assessment of Microbial Polysaccharide Gums as Used in Cosmetics. International Journal of Toxicology 35:1_suppl, pages 5S-49S.
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Filomena Freitas, Christophe Roca & Maria A. M. Reis. 2015. Handbook of Polymers for Pharmaceutical Technologies. Handbook of Polymers for Pharmaceutical Technologies 61 103 .
Lizhen Zeng, Chen Yu, Da Fu, Huangping Lu, Ruiyu Zhu, Laifeng Lu, Xiaodong Zheng & Ting Yu. (2015) Improvement in the effectiveness of Cryptococcus laurentii to control postharvest blue mold of pear by its culture in β-glucan amended nutrient broth. Postharvest Biology and Technology 104, pages 26-32.
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T.P. Smina, D.K. Maurya, T.P.A. Devasagayam & K.K. Janardhanan. (2015) Protection of radiation induced DNA and membrane damages by total triterpenes isolated from Ganoderma lucidum (Fr.) P. Karst. Chemico-Biological Interactions 233, pages 1-7.
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Meng Li, Huashan Shi, Yandong Mu, Zichao Luo, Hailong Zhang, Yang Wan, Dongmei Zhang, Lian Lu, Ke Men, Yaomei Tian, Xiaozhe Wu, Xiaoyan Liu, Ying Pan, Yingzi Fan, Chaoheng Yu, Bailing Zhou, Rong Xiang, Xiancheng Chen & Li Yang. (2014) Effective inhibition of melanoma tumorigenesis and growth via a new complex vaccine based on NY-ESO-1-alum-polysaccharide-HH2. Molecular Cancer 13:1.
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Hongliang Dong, Hui Dai, Xiaomin Hu, Si-Dong Xiong & Xiao-Ming Gao. (2014) The (1→6)-β-Glucan Moiety Represents a Cross-Reactive Epitope of Infection-Induced Malignancy Surveillance. The Journal of Immunology 192:3, pages 1302-1312.
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Shiu-Nan Chen, Ching-Sheng Chang, Ming-Hsin Hung, Sherwin Chen, William Wang, Cheng-Jeng Tai & Chung-Lun Lu. (2014) The Effect of Mushroom Beta-Glucans from Solid Culture of Ganoderma lucidum on Inhibition of the Primary Tumor Metastasis . Evidence-Based Complementary and Alternative Medicine 2014, pages 1-7.
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Bin Du & Baojun Xu. (2014) Oxygen radical absorbance capacity (ORAC) and ferric reducing antioxidant power (FRAP) of β-glucans from different sources with various molecular weight. Bioactive Carbohydrates and Dietary Fibre 3:1, pages 11-16.
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Iuliana Shapira, Keith Sultan, Annette Lee & Emanuela Taioli. (2013) Evolving Concepts: How Diet and the Intestinal Microbiome Act as Modulators of Breast Malignancy. ISRN Oncology 2013, pages 1-10.
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K. C. Carpenter, W. L. Breslin, T. Davidson, A. Adams & B. K. McFarlin. (2012) Baker's yeast β-glucan supplementation increases monocytes and cytokines post-exercise: implications for infection risk?. British Journal of Nutrition 109:3, pages 478-486.
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Shawn M. Talbott, Julie A. Talbott, Tracy L. Talbott & Elaine Dingler. (2012) β ‐Glucan supplementation, allergy symptoms, and quality of life in self‐described ragweed allergy sufferers . Food Science & Nutrition 1:1, pages 90-101.
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H. Dai, X.-Q. Han, F.-Y. Gong, H. Dong, P.-F. Tu & X.-M. Gao. (2012) Structure elucidation and immunological function analysis of a novel  -glucan from the fruit bodies of Polyporus umbellatus (Pers.) Fries. Glycobiology 22:12, pages 1673-1683.
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S.N. Chen, F.H. Nan, S. Chen, J.F. Wu, C.L. Lu & Madhu G. Soni. (2011) Safety assessment of mushroom β-glucan: Subchronic toxicity in rodents and mutagenicity studies. Food and Chemical Toxicology 49:11, pages 2890-2898.
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Vaclav Vetvicka, Sujata Saraswat-Ohri, Aruna Vashishta, Karine Descroix, Frank Jamois, Jean-Claude Yvin & Vincent Ferrières. (2011) New 4-deoxy-(1→3)-β-d-glucan-based oligosaccharides and their immunostimulating potential. Carbohydrate Research 346:14, pages 2213-2221.
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