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Research Paper

Pheophorbide a based photodynamic therapy induces apoptosis via mitochondrial-mediated pathway in human uterine carcinosarcoma

Pages 533-539 | Published online: 15 Mar 2009

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Shuai Dong, Hongxi Shi, Xintong Zhang, Xi Chen, Donghui Cao, Chuanbin Mao, Xiang Gao & Li Wang. (2018) Difunctional bacteriophage conjugated with photosensitizers for Candida albicans-targeting photodynamic inactivation. International Journal of Nanomedicine 13, pages 2199-2216.
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Articles from other publishers (41)

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Andrew M. Korolchuk, Vladimir A. Zolottsev & Alexander Y. Misharin. (2023) Conjugates of Tetrapyrrolic Macrocycles as Potential Anticancer Target-Oriented Photosensitizers. Topics in Current Chemistry 381:2.
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Assunta Saide, Gennaro Riccio, Adrianna Ianora & Chiara Lauritano. (2023) The Diatom Cylindrotheca closterium and the Chlorophyll Breakdown Product Pheophorbide a for Photodynamic Therapy Applications. Applied Sciences 13:4, pages 2590.
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Manish Jain, Jordan Bouilloux, Ines Borrego, Stéphane Cook, Hubert van den Bergh, Norbert Lange, Georges Wagnieres & Marie-Noelle Giraud. (2022) Cathepsin B-Cleavable Polymeric Photosensitizer Prodrug for Selective Photodynamic Therapy: In Vitro Studies. Pharmaceuticals 15:5, pages 564.
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Tomasz Piotr Kubrak, Przemysław Kołodziej, Jan Sawicki, Anna Mazur, Katarzyna Koziorowska & David Aebisher. (2022) Some Natural Photosensitizers and Their Medicinal Properties for Use in Photodynamic Therapy. Molecules 27:4, pages 1192.
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Francesca Moret, Luca Menilli, Manuele Battan, Daniele Tedesco, Marta Columbaro, Andrea Guerrini, Greta Avancini, Claudia Ferroni & Greta Varchi. (2021) Pheophorbide A and Paclitaxel Bioresponsive Nanoparticles as Double-Punch Platform for Cancer Therapy. Pharmaceutics 13:8, pages 1130.
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Dominika Činčárová, Jan Hájek, Martin Dobřichovský, Martin Lukeš & Pavel Hrouzek. (2021) Recommendations on the quantitative analysis of pheophorbides, photosensitizers present in algal biomass intended as food supplement. Algal Research 56, pages 102298.
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Tushar Dubey & Subashchandrabose Chinnathambi. (2021) Photodynamic sensitizers modulate cytoskeleton structural dynamics in neuronal cells. Cytoskeleton 78:6, pages 232-248.
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Ratchanee Duangrat, Anuttara Udomprasert & Thaned Kangsamaksin. (2020) Tetrahedral DNA nanostructures as drug delivery and bioimaging platforms in cancer therapy. Cancer Science 111:9, pages 3164-3173.
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Assunta Saide, Chiara Lauritano & Adrianna Ianora. (2020) Pheophorbide a: State of the Art. Marine Drugs 18:5, pages 257.
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Sharan Bobbala, Sean D. Allen, Sijia Yi, Michael Vincent, Molly Frey, Nicholas B. Karabin & Evan A. Scott. (2020) Employing bicontinuous-to-micellar transitions in nanostructure morphology for on-demand photo-oxidation responsive cytosolic delivery and off–on cytotoxicity. Nanoscale 12:9, pages 5332-5340.
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Vladimíra Pavlíčková, Michal Jurášek, Silvie Rimpelová, Kamil Záruba, David Sedlák, Markéta Šimková, David Kodr, Eliška Staňková, Jan Fähnrich, Zdeňka Rottnerová, Petr Bartůněk, Oldřich Lapčík, Pavel Drašar & Tomáš Ruml. (2019) Oxime-based 19-nortestosterone–pheophorbide a conjugate: bimodal controlled release concept for PDT . Journal of Materials Chemistry B 7:36, pages 5465-5477.
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Babita Kaundal, Anup K. Srivastava, Mohammed Nadim Sardoiwala, Surajit Karmakar & Subhasree Roy Choudhury. (2019) A NIR-responsive indocyanine green-genistein nanoformulation to control the polycomb epigenetic machinery for the efficient combinatorial photo/chemotherapy of glioblastoma. Nanoscale Advances 1:6, pages 2188-2207.
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Behzad Mansoori, Ali Mohammadi, Mohammad Amin Doustvandi, Fatemeh Mohammadnejad, Farzin Kamari, Morten F. Gjerstorff, Behzad Baradaran & Michael R. Hamblin. (2019) Photodynamic therapy for cancer: Role of natural products. Photodiagnosis and Photodynamic Therapy 26, pages 395-404.
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Julien Massiot, Véronique Rosilio, Nada Ibrahim, Akihisa Yamamoto, Valérie Nicolas, Oleg Konovalov, Motomu Tanaka & Ali Makky. (2018) Newly Synthesized Lipid–Porphyrin Conjugates: Evaluation of Their Self‐Assembling Properties, Their Miscibility with Phospholipids and Their Photodynamic Activity In Vitro. Chemistry – A European Journal 24:72, pages 19179-19194.
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E. O. Sousa, R. Braz-Filho, H. D. M. Coutinho, I. R. A. Menezes, F. F. G. Rodrigues & J. G. M. Costa. (2018) New 132-epi-Phaeophorbide a Ethyl Ester from Lantana camara. Chemistry of Natural Compounds 54:6, pages 1114-1117.
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Taher Gheewala, Troy Skwor & Gnanasekar Munirathinam. (2018) Photodynamic therapy using pheophorbide and 670 nm LEDs exhibits anti-cancer effects in-vitro in androgen dependent prostate cancer. Photodiagnosis and Photodynamic Therapy 21, pages 130-137.
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Fabrizio Araniti, Teodoro Coba de la Peña & Adela M. Sánchez-Moreiras. 2018. Advances in Plant Ecophysiology Techniques. Advances in Plant Ecophysiology Techniques 195 213 .
Taher Gheewala, Troy Skwor & Gnanasekar Munirathinam. (2017) Photosensitizers in prostate cancer therapy. Oncotarget 8:18, pages 30524-30538.
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Rubén Ruiz-González, Paula Milán, Roger Bresolí-Obach, Juan Stockert, Angeles Villanueva, Magdalena Cañete & Santi Nonell. (2017) Photodynamic Synergistic Effect of Pheophorbide a and Doxorubicin in Combined Treatment against Tumoral Cells. Cancers 9:12, pages 18.
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Kavita Singh & Vinay Kumar Singh. (2016) Pheophorbide a Potential Source of Plant Molluscicide to Combat Against Neglected Tropical Disease Fasciolosis. Research Journal of Parasitology 11:1, pages 27-32.
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Ju Hee Kim, Jae Myung Park, Yoon Jin Roh, In-Wook Kim, Tayyaba Hasan & Myung-Gyu Choi. (2015) Enhanced efficacy of photodynamic therapy by inhibiting ABCG2 in colon cancers. BMC Cancer 15:1.
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Tilahun Debele, Sydney Peng & Hsieh-Chih Tsai. (2015) Drug Carrier for Photodynamic Cancer Therapy. International Journal of Molecular Sciences 16:9, pages 22094-22136.
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Josephine Modica-Napolitano & Volkmar Weissig. (2015) Treatment Strategies that Enhance the Efficacy and Selectivity of Mitochondria-Targeted Anticancer Agents. International Journal of Molecular Sciences 16:8, pages 17394-17421.
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Sook Moon, Jung Yoon Bae, Hwa-Kyung Son, Doo Young Lee, Gyeongju Park, Hyun You, Hyojin Ko, Yong-Chul Kim & Jin Kim. (2013) RUNX3 confers sensitivity to pheophorbide a-photodynamic therapy in human oral squamous cell carcinoma cell lines. Lasers in Medical Science 30:2, pages 499-507.
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K.-A. Jung, B.-h. Choi & M.-K. Kwak. (2014) The c-MET/PI3K Signaling Is Associated with Cancer Resistance to Doxorubicin and Photodynamic Therapy by Elevating BCRP/ABCG2 Expression. Molecular Pharmacology 87:3, pages 465-476.
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Zhenlong Zheng, Lianhua Zhu, Xianglan Zhang, Lianhua Li, Sook Moon, Mi Ryung Roh & Zhehu Jin. (2014) RUNX3 expression is associated with sensitivity to pheophorbide a-based photodynamic therapy in keloids. Lasers in Medical Science 30:1, pages 67-75.
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Bo-hyun Choi, In-geun Ryoo, Han Chang Kang & Mi-Kyoung Kwak. (2014) The Sensitivity of Cancer Cells to Pheophorbide a-Based Photodynamic Therapy Is Enhanced by NRF2 Silencing. PLoS ONE 9:9, pages e107158.
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Yu NagaiShin AizawaTakanori IriuchishimaBunsei GotoMasahiro NagaokaYasuaki TokuhashiAkiyoshi Saito. (2014) Phototoxic Effect of Na-Pheophorbide A Toward Osteosarcoma Cells in Vitro Using a Laser Diode . Photomedicine and Laser Surgery 32:9, pages 481-489.
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Laure Gibot, Arnaud Lemelle, Ugo Till, Béatrice Moukarzel, Anne-Françoise Mingotaud, Véronique Pimienta, Pascale Saint-Aguet, Marie-Pierre Rols, Mireille Gaucher, Frédéric Violleau, Christophe Chassenieux & Patricia Vicendo. (2014) Polymeric Micelles Encapsulating Photosensitizer: Structure/Photodynamic Therapy Efficiency Relation. Biomacromolecules 15:4, pages 1443-1455.
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Sang-Gun Ahn. (2013) Pheophorbide a-mediated photodynamic therapy induces autophagy and apoptosis via the activation of MAPKs in human skin cancer cells. Oncology Reports.
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D. D. Xu, W. C. S. Cho, P. Wu, H. M. Lam & A. W. N. Leung. (2011) Photo-activated pheophorbide a inhibits the growth of prostate cancer cells. Laser Physics 21:9, pages 1670-1674.
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Siang Hui Lim, Hong Boon Lee & Anthony Siong Hock Ho. (2011) A New Naturally Derived Photosensitizer and Its Phototoxicity on Head and Neck Cancer Cells. Photochemistry and Photobiology 87:5, pages 1152-1158.
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Li Li, Byoung-chan Bae, Thanh Huyen Tran, Kwon Hyeok Yoon, Kun Na & Kang Moo Huh. (2011) Self-quenchable biofunctional nanoparticles of heparin–folate-photosensitizer conjugates for photodynamic therapy. Carbohydrate Polymers 86:2, pages 708-715.
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Li Li, Hyun Tae Moon, Jin-Young Park, Yu Jung Heo, Yongdoo Choi, Thanh Huyen Tran, Yong-kyu Lee, So Yeon Kim & Kang Moo Huh. (2011) Heparin-based self-assembled nanoparticles for photodynamic therapy. Macromolecular Research 19:5, pages 487-494.
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Ngoc-Ha Bui-Xuan, Patrick Ming-Kuen Tang, Chun-Kwok Wong, Judy Yuet-Wa Chan, Karen Ka Yan Cheung, Jonney Lei Jiang & Kwok-Pui Fung. (2011) Pheophorbide a: A photosensitizer with immunostimulating activities on mouse macrophage RAW 264.7 cells in the absence of irradiation. Cellular Immunology 269:1, pages 60-67.
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Rabie Khattab, Erin Goldberg, Lin Lin & Usha Thiyam. (2010) Quantitative analysis and free-radical-scavenging activity of chlorophyll, phytic acid, and condensed tannins in canola. Food Chemistry 122:4, pages 1266-1272.
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Ngoc-Ha Bui-Xuan, Patrick Ming-Kuen Tang, Chun-Kwok Wong & Kwok-Pui Fung. (2010) Photo-activated pheophorbide-a, an active component of Scutellaria barbata, enhances apoptosis via the suppression of ERK-mediated autophagy in the estrogen receptor-negative human breast adenocarcinoma cells MDA-MB-231. Journal of Ethnopharmacology 131:1, pages 95-103.
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Byoung-chan Bae & Kun Na. (2010) Self-quenching polysaccharide-based nanogels of pullulan/folate-photosensitizer conjugates for photodynamic therapy. Biomaterials 31:24, pages 6325-6335.
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Patrick Ming-Kuen Tang, Ngoc-Ha Bui-Xuan, Chun-Kwok Wong, Wing-Ping Fong & Kwok-Pui Fung. (2010) Pheophorbide a-Mediated Photodynamic Therapy Triggers HLA Class I-Restricted Antigen Presentation in Human Hepatocellular Carcinoma. Translational Oncology 3:2, pages 114-122.
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Patrick Ming-Kuen Tang, Dong-Mei Zhang, Ngoc-Ha Bui Xuan, Stephen Kwok-Wing Tsui, Mary Miu-Yee Waye, Siu-Kai Kong, Wing-Ping Fong & Kwok-Pui Fung. (2009) Photodynamic therapy inhibits p-glycoprotein mediated multidrug resistance via JNK activation in human hepatocellular carcinoma using the photosensitizer pheophorbide a. Molecular Cancer 8:1.
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