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Cell Cycle Volume 10, 2011 - Issue 2
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Nuclear translocation of Skp2 facilitates its destruction in response to TGFβ signaling

Dong Hu University of Pittsburgh School of Medicine and University of Pittsburgh Cancer Institute; Pittsburgh, PA USA
,
Weijun Liu University of Pittsburgh School of Medicine and University of Pittsburgh Cancer Institute; Pittsburgh, PA USA
,
George Wu University of Pittsburgh School of Medicine and University of Pittsburgh Cancer Institute; Pittsburgh, PA USA
&
Yong Wan University of Pittsburgh School of Medicine and University of Pittsburgh Cancer Institute; Pittsburgh, PA USACorrespondence[email protected]
Pages 285-292 | Received 13 Dec 2010, Accepted 16 Dec 2010, Published online: 15 Jan 2011

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Savvas C. Pavlides, Jon Lecanda, Julien Daubriac, Unnati M. Pandya, Patricia Gama, Stephanie Blank, Khushbakhat Mittal, Pratibha Shukla & Leslie I. Gold. (2016) TGF-β activates APC through Cdh1 binding for Cks1 and Skp2 proteasomal destruction stabilizing p27kip1 for normal endometrial growth. Cell Cycle 15:7, pages 931-947.
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Articles from other publishers (12)

Jia Jing, Li Rui, Sun Junyuan, Yang Jinfeng, Hong Zhihao, Lu Weiguo & Jia Zhenyu. (2023) Small-molecule compounds inhibiting S-phase kinase-associated protein 2: A review. Frontiers in Pharmacology 14.
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Rongxin Shang, Jiakuan Chen, Yang Gao, Jijun Chen & Guoliang Han. (2023) TRIM58 Interacts with ZEB1 to Suppress NSCLC Tumor Malignancy by Promoting ZEB1 Protein Degradation via UPP. Disease Markers 2023, pages 1-13.
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Xiang Ma, Yongqing Guo, Yuehong Qi, Hongpeng Zhang, Yuhua Hao, Huaping Zhang & Xiaona Li. (2019) APC-Cdh1 Inhibits the Proliferation and Activation of Oligodendrocyte Precursor Cells after Mechanical Stretch Injury. BioMed Research International 2019, pages 1-9.
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Norman E. Davey & David O. Morgan. (2016) Building a Regulatory Network with Short Linear Sequence Motifs: Lessons from the Degrons of the Anaphase-Promoting Complex. Molecular Cell 64:1, pages 12-23.
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Lea Arnold, Sebastian Höckner & Wolfgang Seufert. (2015) Insights into the cellular mechanism of the yeast ubiquitin ligase APC/C-Cdh1 from the analysis of in vivo degrons. Molecular Biology of the Cell 26:5, pages 843-858.
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Ming Qi, Dongmei Liu, Shuhong Zhang, Peixin Hu & Tan Sang. (2015) Inhibition of S-phase kinase-associated protein�2-mediated p27 degradation suppresses tumorigenesis and the progression of hepatocellular carcinoma. Molecular Medicine Reports.
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FUQIANG XU, XIAOMING ZHU, TAO HAN, XIAONA YOU, FABAO LIU, LIHONG YE, XIAODONG ZHANG, XIAOHONG WANG & YUANQING YAO. (2014) The oncoprotein hepatitis B X-interacting protein promotes the migration of ovarian cancer cells through the upregulation of S-phase kinase-associated protein 2 by Sp1. International Journal of Oncology 45:1, pages 255-263.
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Sayuri Suzuki, Naro Ohashi & Masatoshi Kitagawa. (2012) Roles of the Skp2/p27 axis in the progression of chronic nephropathy. Cellular and Molecular Life Sciences 70:18, pages 3277-3287.
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Yan Lv, Yun Niu, Xiu-min Ding & Xu-qi Xiao. (2012) Oncogenic Role of Skp2 and p27Kip1 in Intraductal Proliferative Lesions of the Breast. Chinese Medical Sciences Journal 27:3, pages 161-166.
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Mazin A. Al-Salihi, Lina Herhaus & Gopal P. Sapkota. (2012) Regulation of the transforming growth factor β pathway by reversible ubiquitylation. Open Biology 2:5, pages 120082.
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Paola Bargagna-Mohan, Riya R. Paranthan, Adel Hamza, Chang-Guo Zhan, Do-Min Lee, Kyung Bo Kim, Daniel L. Lau, Cidambi Srinivasan, Keiko Nakayama, Keiichi I. Nakayama, Harald Herrmann & Royce Mohan. (2012) Corneal Antifibrotic Switch Identified in Genetic and Pharmacological Deficiency of Vimentin. Journal of Biological Chemistry 287:2, pages 989-1006.
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Dong Hu, Xinxian Qiao, George Wu & Yong Wan. (2011) The emerging role of APC/CCdh1 in development. Seminars in Cell & Developmental Biology 22:6, pages 579-585.
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