Search in:

Cell Cycle Volume 11, 2012 - Issue 10

Submit an article Journal homepage

Free access

749

Views

CrossRef citations to date

Altmetric

Extra Views

Wip1 sensitizes p53-negative tumors to apoptosis by regulating the Bax/Bcl-x_L ratio

Anastasia R. Goloudina Institut National de la Santé et de la Recherche Médicale; Unité Mixte de Recherche 866; University of Burgundy; Dijon, France

Sharlyn J. Mazur Laboratory of Cell Biology; National Cancer Institute; National Institutes of Health; Bethesda, MD, USA

Ettore Appella Laboratory of Cell Biology; National Cancer Institute; National Institutes of Health; Bethesda, MD, USA

Carmen Garrido Institut National de la Santé et de la Recherche Médicale; Unité Mixte de Recherche 866; University of Burgundy; Dijon, France; Faculty of Medicine and Pharmacy; University of Burgundy; Dijon, France; Centre Hospitalier Universitaire Dijon; Dijon, France

Oleg N. Demidov Institut National de la Santé et de la Recherche Médicale; Unité Mixte de Recherche 866; University of Burgundy; Dijon, France; Faculty of Medicine and Pharmacy; University of Burgundy; Dijon, FranceCorrespondence[email protected]

Pages 1883-1887 | Published online: 15 May 2012

Cite this article
https://doi.org/10.4161/cc.19901

Full Article
Figures & data
References
Citations
Metrics
Reprints & Permissions
View PDF PDF

Citations (29)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Articles from other publishers (29)

Sheng Yin, Lina Yang, Yiyan Zheng & Rongyu Zang. (2022) Wip1 suppresses angiogenesis through the STAT3-VEGF signalling pathway in serous ovarian cancer. Journal of Ovarian Research 15:1.
Crossref

Victor Clausse, Yuhong Fang, Dingyin Tao, Harichandra D. Tagad, Hongmao Sun, Yuhong Wang, Surendra Karavadhi, Kelly Lane, Zhen-Dan Shi, Olga Vasalatiy, Christopher A. LeClair, Rebecca Eells, Min Shen, Samarjit Patnaik, Ettore Appella, Nathan P. Coussens, Matthew D. Hall & Daniel H. Appella. (2022) Discovery of Novel Small-Molecule Scaffolds for the Inhibition and Activation of WIP1 Phosphatase from a RapidFire Mass Spectrometry High-Throughput Screen. ACS Pharmacology & Translational Science 5:10, pages 993-1006.
Crossref

Rui Kamada, Fuki Kudoh, Shogo Ito, Itsumi Tani, Jose Isagani B. Janairo, James G. Omichinski & Kazuyasu Sakaguchi. (2020) Metal-dependent Ser/Thr protein phosphatase PPM family: Evolution, structures, diseases and inhibitors. Pharmacology & Therapeutics 215, pages 107622.
Crossref

Jie Zhang, Huan Fang, Jinguo Zhang, Wencai Guan & Guoxiong Xu. (2020) Garcinol Alone and in Combination With Cisplatin Affect Cellular Behavior and PI3K/AKT Protein Phosphorylation in Human Ovarian Cancer Cells. Dose-Response 18:2, pages 155932582092673.
Crossref

Victor Clausse, Dingyin Tao, Subrata Debnath, Yuhong Fang, Harichandra D. Tagad, Yuhong Wang, Hongmao Sun, Christopher A. LeClair, Sharlyn J. Mazur, Kelly Lane, Zhen-Dan Shi, Olga Vasalatiy, Rebecca Eells, Lynn K. Baker, Mark J. Henderson, Martin R. Webb, Min Shen, Matthew D. Hall, Ettore Appella, Daniel H. Appella & Nathan P. Coussens. (2019) Physiologically relevant orthogonal assays for the discovery of small-molecule modulators of WIP1 phosphatase in high-throughput screens. Journal of Biological Chemistry 294:46, pages 17654-17668.
Crossref

Sujeenthar Tharmalingam, Shayenthiran Sreetharan, Antone L. Brooks & Douglas R. Boreham. (2019) Re-evaluation of the linear no-threshold (LNT) model using new paradigms and modern molecular studies. Chemico-Biological Interactions 301, pages 54-67.
Crossref

Raziyeh Salmanzadeh, Morteza Eskandani, Ahad Mokhtarzadeh, Somayeh Vandghanooni, Roghaiyeh Ilghami, Hadi Maleki, Nazli Saeeidi & Yadollah Omidi. (2018) Propyl gallate (PG) and tert-butylhydroquinone (TBHQ) may alter the potential anti-cancer behavior of probiotics. Food Bioscience 24, pages 37-45.
Crossref

Zhi-Peng Wang, Ye Tian & Jun Lin. (2017) Role of wild-type p53-induced phosphatase 1 in cancer. Oncology Letters 14:4, pages 3893-3898.
Crossref

Soňa Pecháčková, Kamila Burdová & Libor Macurek. (2017) WIP1 phosphatase as pharmacological target in cancer therapy. Journal of Molecular Medicine 95:6, pages 589-599.
Crossref

Pedro A. Lazo. (2017) Reverting p53 activation after recovery of cellular stress to resume with cell cycle progression. Cellular Signalling 33, pages 49-58.
Crossref

Yanping Feng, Fang Liu, Zhixiang Du, Dongjie Zhao, Jianxin Cheng & Wei Guo. (2017) Wip1 regulates SKOV3 cell apoptosis through the p38 MAPK signaling pathway. Molecular Medicine Reports.
Crossref

B Uyanik, B B Grigorash, A R Goloudina & O N Demidov. (2017) DNA damage-induced phosphatase Wip1 in regulation of hematopoiesis, immune system and inflammation. Cell Death Discovery 3:1.
Crossref

Ruizhen Liu, Xinming Zhong, Jing Zeng, Zhihua Huang, Xiao Li, Hai Xiao, Qin Chen & Dongliang Li. (2017) 3′-Daidzein sulfonate sodium inhibits neuronal apoptosis induced by cerebral ischemia-reperfusion. International Journal of Molecular Medicine 39:4, pages 1021-1028.
Crossref

Xiaoyu Ma, Xiaolong Liu, Di Zhou, Yajiao Bai, Beibei Gao, Zhifeng Zhang & Zhenkui Qin. (2016) The NF-κB pathway participates in the response to sulfide stress in Urechis unicinctus. Fish & Shellfish Immunology 58, pages 229-238.
Crossref

Anastasia R. Goloudina, Elena Y. Kochetkova, Tatyana V. Pospelova & Oleg N. Demidov. (2016) Wip1 phosphatase: between p53 and MAPK kinases pathways. Oncotarget 7:21, pages 31563-31571.
Crossref

Sheng Yin, Pan Wang, Lina Yang, Yang Liu, Yan Wang, Mingming Liu, Zihao Qi, Jiao Meng, Ting-Yan Shi, Gong Yang & Rongyu Zang. (2016) Wip1 suppresses ovarian cancer metastasis through the ATM/AKT/Snail mediated signaling. Oncotarget 7:20, pages 29359-29370.
Crossref

V Clausse, A R Goloudina, B Uyanik, E Y Kochetkova, S Richaud, O A Fedorova, A Hammann, M Bardou, N A Barlev, C Garrido & O N Demidov. (2016) Wee1 inhibition potentiates Wip1-dependent p53-negative tumor cell death during chemotherapy. Cell Death & Disease 7:4, pages e2195-e2195.
Crossref

Sona Pechackova, Kamila Burdova, Jan Benada, Petra Kleiblova, Gabriela Jenikova & Libor Macurek. (2016) Inhibition of WIP1 phosphatase sensitizes breast cancer cells to genotoxic stress and to MDM2 antagonist nutlin-3. Oncotarget 7:12, pages 14458-14475.
Crossref

Chih-Wei Fu, Yun-Jung Hsieh, Tzu Ting Chang, Chia-Ling Chen, Cheng-Yu Yang, Anne Liao, Pei-Wen Hsiao & Wen-Shan Li. (2015) Anticancer efficacy of unique pyridine-based tetraindoles. European Journal of Medicinal Chemistry 104, pages 165-176.
Crossref

A Emelyanov & D V Bulavin. (2014) Wip1 phosphatase in breast cancer. Oncogene 34:34, pages 4429-4438.
Crossref

S. Vimalraj, B. Arumugam, P.J. Miranda & N. Selvamurugan. (2015) Runx2: Structure, function, and phosphorylation in osteoblast differentiation. International Journal of Biological Macromolecules 78, pages 202-208.
Crossref

Xia Ma, Jingling Han, Qiyun Wu, Hanzhang Liu, Shangshi Shi, Cheng Wang, Yueran Wang, Jing Xiao, Jianya Zhao, Junkang Jiang & Chunhua Wan. (2015) Involvement of dysregulated Wip1 in manganese-induced p53 signaling and neuronal apoptosis. Toxicology Letters 235:1, pages 17-27.
Crossref

Yongquan Zhang, Hong Sun, Guangxiang He, An Liu, Fengjun Wang & Lu Wang. (2014) WIP1 regulates the proliferation and invasion of nasopharyngeal carcinoma in vitro. Tumor Biology 35:8, pages 7651-7657.
Crossref

TE-CHUN HSIA, CHIEN-CHIH YU, SHU-CHUN HSU, NOU-YING TANG, HSU-FENG LU, YI-PING HUANG, SHIN-HWAR WU, JAUNG-GENG LIN & JING-GUNG CHUNG. (2014) Cantharidin induces apoptosis of H460 human lung cancer cells through mitochondria-dependent pathways. International Journal of Oncology 45:1, pages 245-254.
Crossref

Ji-Seon Lee, Jeong-Rak Park, Ok-Seon Kwon, Hyongbum Kim, Albert J. FornaceJr.Jr. & Hyuk-Jin Cha. (2014) Off-target response of a Wip1 chemical inhibitor in skin keratinocytes. Journal of Dermatological Science 73:2, pages 125-134.
Crossref

J-Y Song, S-H Ryu, Y M Cho, Y S Kim, B-M Lee, S-W Lee & J Choi. (2013) Wip1 suppresses apoptotic cell death through direct dephosphorylation of BAX in response to γ-radiation. Cell Death & Disease 4:8, pages e744-e744.
Crossref

Rouba Hage-Sleiman, Maria Esmerian, Hadile Kobeissy & Ghassan Dbaibo. (2013) p53 and Ceramide as Collaborators in the Stress Response. International Journal of Molecular Sciences 14:3, pages 4982-5012.
Crossref

Zhou Yunlei, Chen Zhe, Lei Yan, Wang Pengcheng, Zheng Yanbo, Sun Le & Liang Qianjin. (2012) INMAP, a novel truncated version of POLR3B, represses AP-1 and p53 transcriptional activity. Molecular and Cellular Biochemistry 374:1-2, pages 81-89.
Crossref

S. Manoharan, D. Palanimuthu, N. Baskaran & S. Silvan. (2012) Modulating Effect of Lupeol on the Expression Pattern of Apoptotic Markers in 7, 12-Dimethylbenz(a)anthracene Induced Oral Carcinogenesis. Asian Pacific Journal of Cancer Prevention 13:11, pages 5753-5757.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Share icon
Back to Top

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.

People also read
Recommended articles
Cited by

To cite this article:

Reference style: APA Chicago Harvard

Citation copied to clipboard

Reference styles above use APA (6th edition), Chicago (16th edition) & Harvard (10th edition)

Download citation

Download a citation file in RIS format that can be imported by citation management software including EndNote, ProCite, RefWorks and Reference Manager.

Choose format: RIS BibTex RefWorks Direct Export

Choose options: Citation Citation & abstract Citation & references

Wip1 sensitizes p53-negative tumors to apoptosis by regulating the Bax/Bcl-x_L ratio

Articles from other publishers (29)

Information for

Open access

Opportunities

Help and information

Your download is now in progress and you may close this window

Login or register to access this feature

Wip1 sensitizes p53-negative tumors to apoptosis by regulating the Bax/Bcl-xL ratio

Citations (29)

Articles from other publishers (29)

Reprints and Corporate Permissions

Academic Permissions

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date

Wip1 sensitizes p53-negative tumors to apoptosis by regulating the Bax/Bcl-x_L ratio