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Review: Spotlight on Cardiology

Cyclins That Don’t Cycle : Cyclin T/Cyclin-Dependent Kinase-9 Determines Cardiac Muscle Cell Size

Pages 98-104 | Published online: 07 Mar 2003

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Toshitsugu Fujita & Werner Schlegel. (2010) Promoter-proximal pausing of RNA polymerase II: an opportunity to regulate gene transcription. Journal of Receptors and Signal Transduction 30:1, pages 31-42.
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Annemieke A. Michels, Van Trung Nguyen, Alessandro Fraldi, Valérie Labas, Mia Edwards, François Bonnet, Luigi Lania & Olivier Bensaude. (2003) MAQ1 and 7SK RNA Interact with CDK9/Cyclin T Complexes in a Transcription-Dependent Manner. Molecular and Cellular Biology 23:14, pages 4859-4869.
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Sylvain Egloff. (2021) CDK9 keeps RNA polymerase II on track. Cellular and Molecular Life Sciences 78:14, pages 5543-5567.
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Marwa Matboli, Ayman E. Shafei, Sara H.A. Agwa, Sherif Sammir Elzahy, Ahmed K. Anwar, Amr R. Mansour, Ahmed I. Gaber, Ali E.A. Said, Paula Lwis & Marwa Hamdy. (2019) Identification of Novel Molecular Network Expression in Acute Myocardial Infarction. Current Genomics 20:5, pages 340-348.
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Sailay Siddiqi & Mark A. Sussman. (2014) The Heart: Mostly Postmitotic or Mostly Premitotic? Myocyte Cell Cycle, Senescence, and Quiescence. Canadian Journal of Cardiology 30:11, pages 1270-1278.
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Ajay K. Jha, Yixing Wang, Brian S. Hercyk, Hwa-Soo Shin, Rujin Chen & Ming Yang. (2014) The role for CYCLIN A1;2/TARDY ASYNCHRONOUS MEIOSIS in differentiated cells in Arabidopsis. Plant Molecular Biology 85:1-2, pages 81-94.
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Brian M. Friedrich, Natallia Dziuba, Guangyu Li, Mark A. Endsley, James L. Murray & Monique R. Ferguson. (2011) Host factors mediating HIV-1 replication. Virus Research 161:2, pages 101-114.
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Józefa Węsierska-Gądek, Margarita Maurer, Nora Zulehner & Oxana Komina. (2011) Whether to target single or multiple CDKs for therapy? That is the question. Journal of Cellular Physiology 226:2, pages 341-349.
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Judit Garriga, Hongbo Xie, Zoran Obradovic & Xavier Graña. (2010) Selective control of gene expression by CDK9 in human cells. Journal of Cellular Physiology 222:1, pages 200-208.
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Józefa Węsierska-GądekIvo Chamrád & Vladimír Kryštof. (2009) Novel potent pharmacological cyclin-dependent kinase inhibitors. Future Medicinal Chemistry 1:9, pages 1561-1581.
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A Satyanarayana & P Kaldis. (2009) Mammalian cell-cycle regulation: several Cdks, numerous cyclins and diverse compensatory mechanisms. Oncogene 28:33, pages 2925-2939.
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Eduardo Mascareno, Irena Manukyan, Dipak K. Das & M. A. Q. Siddiqui. (2008) Down‐regulation of cardiac lineage protein (CLP‐1) expression in CLP‐1 +/− mice affords cardioprotection against ischaemic stress. Journal of Cellular and Molecular Medicine 13:8b, pages 2744-2753.
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Jorge Espinoza-DeroutMichael WagnerLouis SalciccioliJason M. LazarSikha BhaduriEduardo MascarenoBrahim ChaqourM.A.Q. Siddiqui. (2009) Positive Transcription Elongation Factor b Activity in Compensatory Myocardial Hypertrophy is Regulated by Cardiac Lineage Protein-1. Circulation Research 104:12, pages 1347-1354.
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Haiqing Zhu, Joanne R. Doherty, Emin Kuliyev & Paul E. Mead. (2009) CDK9/cyclin complexes modulate endoderm induction by direct interaction with Mix.3/ mixer . Developmental Dynamics 238:6, pages 1346-1357.
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Masanori Nojima, Yehong Huang, Mudit Tyagi, Hung-Ying Kao & Koh Fujinaga. (2008) The Positive Transcription Elongation Factor b Is an Essential Cofactor for the Activation of Transcription by Myocyte Enhancer Factor 2. Journal of Molecular Biology 382:2, pages 275-287.
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Marcos Malumbres. 2008. Principles of Molecular Oncology. Principles of Molecular Oncology 207 237 .
Li Wang, Jie Zhang & Karl Herrup. 2008. Cyclin Dependent Kinase 5 (Cdk5). Cyclin Dependent Kinase 5 (Cdk5) 119 137 .
Tara M. Young, Michael Tsai, Bin Tian, Michael B. Mathews & Tsafi Pe'ery. (2007) Cellular mRNA Activates Transcription Elongation by Displacing 7SK RNA. PLoS ONE 2:10, pages e1010.
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Maitreyi Das, David J. Wiley, Saskia Medina, Helen A. Vincent, Michelle Larrea, Andrea Oriolo & Fulvia Verde. (2007) Regulation of Cell Diameter, For3p Localization, and Cell Symmetry by Fission Yeast Rho-GAP Rga4p. Molecular Biology of the Cell 18:6, pages 2090-2101.
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Qintong Li, Jeffrey J. Cooper, Gary H. Altwerger, Michael D. Feldkamp, Madeline A. Shea & David H. Price. (2007) HEXIM1 is a promiscuous double-stranded RNA-binding protein and interacts with RNAs in addition to 7SK in cultured cells. Nucleic Acids Research 35:8, pages 2503-2512.
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Andreia Machado Leopoldino, Fernanda Canduri, Hamilton Cabral, Magno Junqueira, Alessandra Bernadete Trovó de Marqui, Luciano H. Apponi, Isabel Osório da Fonseca, Gilberto Barbosa Domont, Diógenes S. Santos, Sandro Valentini, Gustavo Orlando Bonilla-Rodriguez, Marcelo Andrés Fossey, Walter Filgueira de AzevedoJr.Jr. & Eloiza Helena Tajara. (2006) Expression, purification, and circular dichroism analysis of human CDK9. Protein Expression and Purification 47:2, pages 614-620.
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Jayalakshmi Sridhar, Nagaraju Akula & Nagarajan Pattabiraman. (2006) Selectivity and potency of cyclin-dependent kinase inhibitors. The AAPS Journal 8:1, pages E204-E221.
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Maureen Caligiuri, Frank Becker, Krishna Murthi, Faith Kaplan, Severine Dedier, Christine Kaufmann, Andy Machl, Gabriele Zybarth, Judson Richard, Nick Bockovich, Art Kluge & Nikolai Kley. (2005) A Proteome-Wide CDK/CRK-Specific Kinase Inhibitor Promotes Tumor Cell Death in the Absence of Cell Cycle Progression. Chemistry & Biology 12:10, pages 1103-1115.
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Qintong Li, Jason P. Price, Sarah A. Byers, Dongmei Cheng, Junmin Peng & David H. Price. (2005) Analysis of the Large Inactive P-TEFb Complex Indicates That It Contains One 7SK Molecule, a Dimer of HEXIM1 or HEXIM2, and Two P-TEFb Molecules Containing Cdk9 Phosphorylated at Threonine 186. Journal of Biological Chemistry 280:31, pages 28819-28826.
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Sarah A. Byers, Jason P. Price, Jeffrey J. Cooper, Qintong Li & David H. Price. (2005) HEXIM2, a HEXIM1-related Protein, Regulates Positive Transcription Elongation Factor b through Association with 7SK. Journal of Biological Chemistry 280:16, pages 16360-16367.
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Olga A. Koroleva, Matthew L. Tomlinson, David Leader, Peter Shaw & John H. Doonan. (2004) High-throughput protein localization in Arabidopsis using Agrobacterium-mediated transient expression of GFP-ORF fusions. The Plant Journal 41:1, pages 162-174.
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Judit Garriga & Xavier Graña. (2004) Cellular control of gene expression by T-type cyclin/CDK9 complexes. Gene 337, pages 15-23.
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Ruichuan Chen, Zhiyuan Yang & Qiang Zhou. (2004) Phosphorylated Positive Transcription Elongation Factor b (P-TEFb) Is Tagged for Inhibition through Association with 7SK snRNA. Journal of Biological Chemistry 279:6, pages 4153-4160.
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