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MYC directs transcription of MCL1 and eIF4E genes to control sensitivity of gastric cancer cells toward HDAC inhibitors

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Pages 1593-1602 | Published online: 15 Apr 2012

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Yingyan Han, Zhi Wang, Shujuan Sun, Zeyu Zhang, Jia Liu, Xin Jin, Peng Wu, Teng Ji, Wencheng Ding, Beibei Wang & Qinglei Gao. (2020) Decreased DHRS2 expression is associated with HDACi resistance and poor prognosis in ovarian cancer. Epigenetics 15:1-2, pages 122-133.
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Filippa Pettersson, Sonia V del Rincon & Wilson H Miller$suffix/text()$suffix/text(). (2014) Eukaryotic translation initiation factor 4E as a novel therapeutic target in hematological malignancies and beyond. Expert Opinion on Therapeutic Targets 18:9, pages 1035-1048.
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Amandine Badie, Christian Gaiddon & Georg Mellitzer. (2022) Histone Deacetylase Functions in Gastric Cancer: Therapeutic Target?. Cancers 14:21, pages 5472.
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Khaled Alsayegh, Katsuhisa Matsuura, Hidekazu Sekine & Tatsuya Shimizu. (2017) Dinaciclib potently suppresses MCL-1 and selectively induces the cell death in human iPS cells without affecting the viability of cardiac tissue. Scientific Reports 7:1.
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Xingchao Zhu, Kaiguang Zhang, Qiaomin Wang, Si Chen, Yawen Gou, Yufang Cui & Qin Li. (2015) Cisplatin-mediated c-myc overexpression and cytochrome c (cyt c) release result in the up-regulation of the death receptors DR4 and DR5 and the activation of caspase 3 and caspase 9, likely responsible for the TRAIL-sensitizing effect of cisplatin. Medical Oncology 32:4.
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Tobias Wagner, Peter Brand, Thorsten Heinzel & Oliver H. Krämer. (2014) Histone deacetylase 2 controls p53 and is a critical factor in tumorigenesis. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1846:2, pages 524-538.
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Lorenzo Colarossi, Lorenzo Memeo, Cristina Colarossi, Eleonora Aiello, Antonio Iuppa, Virginia Espina, Lance Liotta & Claudius Mueller. (2014) Inhibition of histone deacetylase 4 increases cytotoxicity of docetaxel in gastric cancer cells. PROTEOMICS - Clinical Applications 8:11-12, pages 924-931.
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Edmond Chipumuro, Eugenio Marco, Camilla L. Christensen, Nicholas Kwiatkowski, Tinghu Zhang, Clark M. Hatheway, Brian J. Abraham, Bandana Sharma, Caleb Yeung, Abigail Altabef, Antonio Perez-Atayde, Kwok-Kin Wong, Guo-Cheng Yuan, Nathanael S. Gray, Richard A. Young & Rani E. George. (2014) CDK7 Inhibition Suppresses Super-Enhancer-Linked Oncogenic Transcription in MYCN-Driven Cancer. Cell 159:5, pages 1126-1139.
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