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Cell Cycle News & Views

p53-dependent growth arrest and induction of p21: A critical role for PCAF-mediated histone acetylation

Page 2591 | Received 12 Jun 2012, Accepted 15 Jun 2012, Published online: 15 Jul 2012

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Giovanni Chillemi, Pavel Davidovich, Marco D’Abramo, Tazhir Mametnabiev, Alexander Vasilievich Garabadzhiu, Alessandro Desideri & Gerry Melino. (2013) Molecular dynamics of the full-length p53 monomer. Cell Cycle 12:18, pages 3098-3108.
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Jinze Shen, Qurui Wang, Yunan Mao, Wei Gao & Shiwei Duan. (2023) Targeting the p53 signaling pathway in cancers: Molecular mechanisms and clinical studies. MedComm 4:3.
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Izabela Szymczak-Pajor, Józef Drzewoski, Ewa Świderska, Justyna Strycharz, Anna Gabryanczyk, Jacek Kasznicki, Marta Bogdańska & Agnieszka Śliwińska. (2023) Metformin Induces Apoptosis in Human Pancreatic Cancer (PC) Cells Accompanied by Changes in the Levels of Histone Acetyltransferases (Particularly, p300/CBP-Associated Factor (PCAF) Protein Levels). Pharmaceuticals 16:1, pages 115.
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Shumin Zhou, Pin Li, Li Qin, Shuhong Huang & Ningning Dang. (2022) Transcription factor YY1 contributes to human melanoma cell growth through modulating the p53 signalling pathway. Experimental Dermatology 31:10, pages 1563-1578.
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Chao Xu, Su Ni, Chao Zhuang, Chenkai Li, Gongyin Zhao, Shijie Jiang, Liangliang Wang, Ruixia Zhu, Andre J. van Wijnen & Yuji Wang. (2021) Polysaccharide from Angelica sinensis attenuates SNP-induced apoptosis in osteoarthritis chondrocytes by inducing autophagy via the ERK1/2 pathway. Arthritis Research & Therapy 23:1.
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Yixin Xu, Jia Liu, Tao Jiang, Linsen Shi, Liang Shang, Jun Song & Leping Li. (2021) PDRG1 predicts a poor prognosis and facilitates the proliferation and metastasis of colorectal cancer. Experimental Cell Research 409:2, pages 112924.
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Yiwei Liu, Hairong Chen, Xiangcheng Li, Feng Zhang, Lianbao Kong, Xuehao Wang, Jin Bai & Xiaofeng Wu. (2021) PSMC2 Regulates Cell Cycle Progression Through the p21/Cyclin D1 Pathway and Predicts a Poor Prognosis in Human Hepatocellular Carcinoma. Frontiers in Oncology 11.
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Lijun Zhao, Kexin Hu, Jianzhong Cao, Pan Wang, Jun Li, Kewu Zeng, Xiaodong He, Peng-Fei Tu, Tanjun Tong & Limin Han. (2019) lncRNA miat functions as a ceRNA to upregulate sirt1 by sponging miR-22-3p in HCC cellular senescence. Aging 11:17, pages 7098-7122.
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Kelly Goulart Lima, Gabriele Catyana Krause, Elisa Feller Gonçalves da Silva, Léder Leal Xavier, Léo Anderson Meira Martins, Laura Manzoli Alice, Luiza Bueno da Luz, Rodrigo Benedetti Gassen, Eduardo Cremonese Filippi-Chiela, Gabriela Viegas Haute, Maria Claudia Rosa Garcia, Giselle Afonso Funchal, Leonardo Pedrazza, Camille Kirinus Reghelin & Jarbas Rodrigues de Oliveira. (2018) Octyl gallate reduces ATP levels and Ki67 expression leading HepG2 cells to cell cycle arrest and mitochondria-mediated apoptosis. Toxicology in Vitro 48, pages 11-25.
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Dongfang Liu, Jingjing Zhang, Yang Wu, Guodong Shi, Hao Yuan, Zipeng Lu, Qicong Zhu, Pengfei Wu, Cheng Lu, Feng Guo, Jianmin Chen, Kuirong Jiang & Yi Miao. (2017) RETRACTED: YY1 suppresses proliferation and migration of pancreatic ductal adenocarcinoma by regulating the CDKN3/MdM2/P53/P21 signaling pathway . International Journal of Cancer 142:7, pages 1392-1404.
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Guihua Wang, Yinjia Fu, Fuqing Hu, Jinqing Lan, Feng Xu, Xi Yang, Xuelai Luo, Jing Wang & Junbo Hu. (2017) Loss of BRG1 induces CRC cell senescence by regulating p53/p21 pathway. Cell Death & Disease 8:2, pages e2607-e2607.
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Jing Zhang, Liangfang Shen & Lun-Quan Sun. (2015) The regulation of radiosensitivity by p53 and its acetylation. Cancer Letters 363:2, pages 108-118.
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Shuguang Zhang, Guan Sun, Zhimin Wang, Yi Wan, Jun Guo & Lei Shi. (2014) PCAF-mediated Akt1 acetylation enhances the proliferation of human glioblastoma cells. Tumor Biology 36:3, pages 1455-1462.
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Qiao Jing Lew, Kai Ling Chu, Yi Ling Chia, Benjamin Soo, Jia Pei Ho, Chew Har Ng, Hui Si Kwok, Cheng-Ming Chiang, Yao Chang & Sheng-Hao Chao. (2014) GCN5 inhibits XBP-1S-mediated transcription by antagonizing PCAF action. Oncotarget 6:1, pages 271-287.
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KEMIN CAI, YI WAN, ZHIMIN WANG, YU WANG, XIAOJUN ZHAO & XUELI BAO. (2014) C5a promotes the proliferation of human nasopharyngeal carcinoma cells through PCAF-mediated STAT3 acetylation. Oncology Reports 32:5, pages 2260-2266.
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C. Blattmann, M. Thiemann, A. Stenzinger, A. Christmann, E. Roth, V. Ehemann, J. Debus, A.E. Kulozik, W. Weichert, P.E. Huber, S. Oertel & A. Abdollahi. (2013) Radiosensitization by histone deacetylase inhibition in an osteosarcoma mouse modelRadiosensitivierung durch Histon-Deacetylasehemmung im Osteosarkom- Mausmodell. Strahlentherapie und Onkologie 189:11, pages 957-966.
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