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Cell Cycle Volume 12, 2013 - Issue 1
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Lin28 regulates BMP4 and functions with Oct4 to affect ovarian tumor microenvironment

Wei Ma Department of Obstetrics, Gynecology and Reproductive Sciences; Yale Stem Cell Center; Yale University School of Medicine; New Haven, CT USA; Clinical Department; School of Medicine; Northwest University for Nationalities; Lanzhou, Gansu, P.R. China
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Jing Ma Department of Obstetrics, Gynecology and Reproductive Sciences; Yale Stem Cell Center; Yale University School of Medicine; New Haven, CT USA; Obstetrics and Gynecology Department; Third Xiangya Hospital of Central South University; Changsha, Hunan, P.R. China
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Jie Xu Department of Obstetrics, Gynecology and Reproductive Sciences; Yale Stem Cell Center; Yale University School of Medicine; New Haven, CT USA
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Chong Qiao Department of Obstetrics, Gynecology and Reproductive Sciences; Yale Stem Cell Center; Yale University School of Medicine; New Haven, CT USA; Department of Obstetrics and Gynecology; Shengjing Hospital; China Medial University; Shengyang, Liaoning, P.R. China
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Adam Branscum Biostatistics Program; School of Biological and Population Health Sciences; Oregon State University; Corvallis, OR USA
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Andres Cardenas Biostatistics Program; School of Biological and Population Health Sciences; Oregon State University; Corvallis, OR USA
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Andre T. Baron Department of Epidemiology; University of Kentucky; Lexington, KY USA; Department of Obstetrics and Gynecology; Division of Gynecologic Oncology; University of Kentucky; Lexington, KY USA
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Peter Schwartz Department of Obstetrics, Gynecology and Reproductive Sciences; Yale Stem Cell Center; Yale University School of Medicine; New Haven, CT USA
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Nita J. Maihle Department of Obstetrics, Gynecology and Reproductive Sciences; Yale Stem Cell Center; Yale University School of Medicine; New Haven, CT USA; Department of Pathology; Yale University School of Medicine; New Haven, CT USA
&
Yingqun Huang Department of Obstetrics, Gynecology and Reproductive Sciences; Yale Stem Cell Center; Yale University School of Medicine; New Haven, CT USACorrespondence[email protected]
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Pages 88-97 | Published online: 19 Dec 2012

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Karen McLean. (2013) BMPs morph into new roles in ovarian cancer. Cell Cycle 12:3, pages 389-389.
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Ahmed Maklad, Mohammed Sedeeq, Kai Man Chan, Nuri Gueven & Iman Azimi. (2023) Exploring Lin28 proteins: Unravelling structure and functions with emphasis on nervous system malignancies. Life Sciences 335, pages 122275.
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Yu Qiao, Oluwafemi Solomon Agboola, Xinglin Hu, Yanshuang Wu & Lei Lei. (2020) Tumorigenic and Immunogenic Properties of Induced Pluripotent Stem Cells: a Promising Cancer Vaccine. Stem Cell Reviews and Reports 16:6, pages 1049-1061.
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Abhijeet Behera, Rahail Ashraf, Amit Kumar Srivastava & Sanjay Kumar. (2020) Bioinformatics analysis and verification of molecular targets in ovarian cancer stem-like cells. Heliyon 6:9, pages e04820.
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Tempei Sato, Kensuke Kataoka, Yoshiaki Ito, Shigetoshi Yokoyama, Masafumi Inui, Masaki Mori, Satoru Takahashi, Keiichi Akita, Shuji Takada, Hiroe Ueno-Kudoh & Hiroshi Asahara. (2020) Lin28a/let-7 pathway modulates the Hox code via Polycomb regulation during axial patterning in vertebrates. eLife 9.
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Katja Kaipio, Ping Chen, Pia Roering, Kaisa Huhtinen, Piia Mikkonen, Päivi Östling, Laura Lehtinen, Naziha Mansuri, Taina Korpela, Swapnil Potdar, Johanna Hynninen, Annika Auranen, Seija Grénman, Krister Wennerberg, Sampsa Hautaniemi & Olli Carpén. (2019) ALDH1A1‐related stemness in high‐grade serous ovarian cancer is a negative prognostic indicator but potentially targetable by EGFR/mTOR‐PI3K/aurora kinase inhibitors. The Journal of Pathology 250:2, pages 159-169.
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Jiayi Zhang, Aiming Xu, Chenkui Miao, Jie Yang, Min Gu & Ninghong Song. (2019) Prognostic value of Lin28A and Lin28B in various human malignancies: a systematic review and meta-analysis. Cancer Cell International 19:1.
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Asghar Ali, Russell V. Anthony, Gerrit J. Bouma & Quinton A. Winger. (2019) LIN28‐ let‐7 axis regulates genes in immortalized human trophoblast cells by targeting the ARID3B‐complex . The FASEB Journal 33:11, pages 12348-12363.
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Ying Wang, Bin Yang, Jinping Zhao, Xiaohui Yu, Xing Liu, Long Zhang, Yunjing Zhang, Xiaoli Li & Zhenhua Zhai. (2019) Epithelial‑mesenchymal transition induced by bone morphogenetic protein 9 hinders cisplatin efficacy in ovarian cancer cells. Molecular Medicine Reports.
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Yao He, Hui Wang, Meina Yan, Xinxin Yang, Rong Shen, Xiaoge Ni, Xiaokun Chen, Peifang Yang, Miao Chen, Xiaodong Lu, Genbao Shao, Xiaoming Zhou & Qixiang Shao. (2018) High LIN28A and PLK4 co‑expression is associated with poor prognosis in epithelial ovarian cancer. Molecular Medicine Reports.
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Xiaofen Wu, Lei Ruan, Yi Yang & Qi Mei. (2017) Analysis of gene expression changes associated with human carcinoma-associated fibroblasts in non-small cell lung carcinoma. Biological Research 50:1.
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Shu Tan, Boya Feng, Mingzhu Yin, Huanjiao Jenny Zhou, Ge Lou, Weidong Ji, Yonghao Li & Wang Min. (2017) Stromal Senp1 promotes mouse early folliculogenesis by regulating BMP4 expression. Cell & Bioscience 7:1.
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Julien Balzeau, Miriam R. Menezes, Siyu Cao & John P. Hagan. (2017) The LIN28/let-7 Pathway in Cancer. Frontiers in Genetics 8.
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Patrícia Benites Gonçalves da Silva, Márcia Cristina Teixeira dos Santos, Carolina Oliveira Rodini, Carolini Kaid, Márcia Cristina Leite Pereira, Gabriela Furukawa, Daniel Sanzio Gimenes da Cruz, Mauricio Barbugiani Goldfeder, Clarissa Ribeiro Reily Rocha, Carla Rosenberg & Oswaldo Keith Okamoto. (2017) High OCT4A levels drive tumorigenicity and metastatic potential of medulloblastoma cells. Oncotarget 8:12, pages 19192-19204.
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Ho Park & Seung Joo Jekal. (2015) MicroRNA-126 Regulates the Expression of Stem Cell Transcription Factors (Sox2 and Lin28) in Various Ovarian Tumors. Korean Journal of Clinical Laboratory Science 47:4, pages 298-305.
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Yun-Jung ChoiPatrick N. IngramKun YangLan CoffmanMangala IyengarShoumei BaiDafydd G. ThomasEuisik YoonRonald J. Buckanovich. (2015) Identifying an ovarian cancer cell hierarchy regulated by bone morphogenetic protein 2. Proceedings of the National Academy of Sciences 112:50.
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Deepa Bhartiya & Jarnail Singh. (2015) FSH–FSHR3–stem cells in ovary surface epithelium: basis for adult ovarian biology, failure, aging, and cancer. REPRODUCTION 149:1, pages R35-R48.
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Bin Bao, Asfar S. Azmi, Amro Aboukameel, Aamir Ahmad, Aliccia Bolling-Fischer, Seema Sethi, Shadan Ali, Yiwei Li, Dejuan Kong, Sanjeev Banerjee, Jessica Back & Fazlul H. Sarkar. (2014) Pancreatic Cancer Stem-like Cells Display Aggressive Behavior Mediated via Activation of FoxQ1. Journal of Biological Chemistry 289:21, pages 14520-14533.
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Yixin Yao, Yinghua Lu, Wen-chi Chen, Yongping Jiang, Tao Cheng, Yupo Ma, Lou Lu & Wei Dai. (2014) Cobalt and Nickel Stabilize Stem Cell Transcription Factor OCT4 through Modulating Its Sumoylation and Ubiquitination. PLoS ONE 9:1, pages e86620.
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Blair B. Madison, Qi Liu, Xue Zhong, Christopher M. Hahn, Nan Lin, Matthew J. Emmett, Ben Z. Stanger, Ju-Seog Lee & Anil K. Rustgi. (2013) LIN28B promotes growth and tumorigenesis of the intestinal epithelium via Let-7. Genes & Development 27:20, pages 2233-2245.
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Garyfallia Papaioannou, Jennifer B. Inloes, Yukio Nakamura, Elena Paltrinieri & Tatsuya Kobayashi. (2013) let-7 and miR-140 microRNAs coordinately regulate skeletal development. Proceedings of the National Academy of Sciences 110:35.
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