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Editorials: Cell Cycle Features

Inactivation of myofibroblasts during regression of liver fibrosis

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Pages 381-382 | Published online: 16 Jan 2013

Keep up to date with the latest research on this topic with citation updates for this article.

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Fujun Yu, Zhongqiu Lu, Jing Cai, Kate Huang, Bicheng Chen, Guojun Li, Peihong Dong & Jianjian Zheng. (2015) MALAT1 functions as a competing endogenous RNA to mediate Rac1 expression by sequestering miR-101b in liver fibrosis. Cell Cycle 14:24, pages 3885-3896.
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Articles from other publishers (33)

Hyun Young Kim, Sadatsugu Sakane, Alvaro Eguileor, Raquel Carvalho Gontijo Weber, Wonseok Lee, Xiao Liu, Kevin Lam, Kei Ishizuka, Sara Brin Rosenthal, Karin Diggle, David A. Brenner & Tatiana Kisseleva. (2024) The Origin and Fate of Liver Myofibroblasts. Cellular and Molecular Gastroenterology and Hepatology 17:1, pages 93-106.
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V. N. Slautin, D. Yu. Grebnev, I. Yu. Maklakova, S. V. Sazonov, I. V. Gavrilov & E. I. Gavrilova. (2023) The effect of fucoxanthin on the development of CCl<sub>4</sub>-induced liver fibrosis. Fundamental and Clinical Medicine 8:2, pages 8-18.
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Ting Guo, Cindy Wantono, Yuyong Tan, Feihong Deng, Tianying Duan & Deliang Liu. (2023) Regulators, functions, and mechanotransduction pathways of matrix stiffness in hepatic disease. Frontiers in Physiology 14.
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Tatjana Seitz & Claus Hellerbrand. (2021) Role of fibroblast growth factor signalling in hepatic fibrosis. Liver International 41:6, pages 1201-1215.
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Salwa A. IbrahimMervat Z. MohamedNashwa F. El-TahawyAly M. Abdelrahman. (2021) Antifibrotic effects of bezafibrate and pioglitazone against thioacetamide-induced liver fibrosis in albino rats. Canadian Journal of Physiology and Pharmacology 99:3, pages 313-320.
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Tatiana Kisseleva & David Brenner. (2020) Molecular and cellular mechanisms of liver fibrosis and its regression. Nature Reviews Gastroenterology & Hepatology 18:3, pages 151-166.
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Klev Diamanti, Juan Salvador Inda Díaz, Amanda Raine, Gang Pan, Claes Wadelius & Marco Cavalli. (2020) Single nucleus transcriptomics data integration recapitulates the major cell types in human liver. Hepatology Research 51:2, pages 233-238.
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Hong Zhu, Changsheng He, Huizi Zhao, Wenjuan Jiang, Songbing Xu, Jun Li, Taotao Ma & Cheng Huang. (2020) Sennoside A prevents liver fibrosis by binding DNMT1 and suppressing DNMT1‐mediated PTEN hypermethylation in HSC activation and proliferation. The FASEB Journal 34:11, pages 14558-14571.
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Danhua Zhou, Wei Huang, Jinhuan Wei, Jingxin Zhang, Zhaoxiu Liu, Ran Ji, Sijia Ge, Mingbing Xiao, Yihui Fan & Cuihua Lu. (2020) RelB promotes liver fibrosis via inducing the release of injury‐associated inflammatory cytokines. Journal of Cellular and Molecular Medicine 24:11, pages 6008-6014.
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Robert F. Schwabe, Ira Tabas & Utpal B. Pajvani. (2020) Mechanisms of Fibrosis Development in Nonalcoholic Steatohepatitis. Gastroenterology 158:7, pages 1913-1928.
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Qinghua Li, Youcheng Ding, Xinlai Guo, Shenggen Luo, Huiren Zhuang, JingE Zhou, Nan Xu & Zhiqiang Yan. (2019) Chemically modified liposomes carrying TRAIL target activated hepatic stellate cells and ameliorate hepatic fibrosis in vitro and in vivo. Journal of Cellular and Molecular Medicine 23:3, pages 1951-1962.
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Anca D. Petrescu, Stephanie Grant, Gabriel Frampton, Matthew McMillin, Jessica Kain, Maheedhar Kodali, Ashok K. Shetty & Sharon DeMorrow. (2018) Gulf war illness-related chemicals increase CD11b/c+ monocyte infiltration into the liver and aggravate hepatic cholestasis in a rodent model. Scientific Reports 8:1.
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Eszter Regős, Hadeer Hesham Abdelfattah, Andrea Reszegi, László Szilák, Klára Werling, Gábor Szabó, András Kiss, Zsuzsa Schaff, Ilona Kovalszky & Kornélia Baghy. (2018) Syndecan-1 inhibits early stages of liver fibrogenesis by interfering with TGFβ1 action and upregulating MMP14. Matrix Biology 68-69, pages 474-489.
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Pardis Pakshir & Boris Hinz. (2018) The big five in fibrosis: Macrophages, myofibroblasts, matrix, mechanics, and miscommunication. Matrix Biology 68-69, pages 81-93.
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Fang-Tian Bu, Yu Chen, Hai-Xia Yu, Xin Chen, Yang Yang, Xue-Yin Pan, Qin Wang, Yu-Ting Wu, Cheng Huang, Xiao-Ming Meng & Jun Li. (2018) SENP2 alleviates CCl4-induced liver fibrosis by promoting activated hepatic stellate cell apoptosis and reversion. Toxicology Letters 289, pages 86-98.
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Min Cong, Jidong Jia, Tatiana Kisseleva & David A. Brenner. 2018. Zakim and Boyer's Hepatology. Zakim and Boyer's Hepatology 77 83.e5 .
Hongyu Zhang, Fangyan Chen, Xu Fan, Cong Lin, Yunwei Hao, Handong Wei, Weiran Lin, Ying Jiang & Fuchu He. (2017) Quantitative Proteomic analysis on Activated Hepatic Stellate Cells reversion Reveal STAT1 as a key regulator between Liver Fibrosis and recovery. Scientific Reports 7:1.
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Yue Yang, Minkyung Bae, Young-Ki Park, Yoojin Lee, Tho X. Pham, Swetha Rudraiah, José Manautou, Sung I. Koo & Ji-Young Lee. (2017) Histone deacetylase 9 plays a role in the antifibrogenic effect of astaxanthin in hepatic stellate cells. The Journal of Nutritional Biochemistry 40, pages 172-177.
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Li Chen, Ruju Chen, Victoria M. Velazquez & David R. Brigstock. (2016) Fibrogenic Signaling Is Suppressed in Hepatic Stellate Cells through Targeting of Connective Tissue Growth Factor (CCN2) by Cellular or Exosomal MicroRNA-199a-5p. The American Journal of Pathology 186:11, pages 2921-2933.
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Natalie J. Torok. (2016) Dysregulation of redox pathways in liver fibrosis. American Journal of Physiology-Gastrointestinal and Liver Physiology 311:4, pages G667-G674.
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David Y Zhang, Nicolas Goossens, Jinsheng Guo, Ming-Chao Tsai, Hsin-I Chou, Civan Altunkaynak, Angelo Sangiovanni, Massimo Iavarone, Massomo Colombo, Masahiro Kobayashi, Hiromitsu Kumada, Augusto Villanueva, Josep M Llovet, Yujin Hoshida & Scott L Friedman. (2016) A hepatic stellate cell gene expression signature associated with outcomes in hepatitis C cirrhosis and hepatocellular carcinoma after curative resection. Gut 65:10, pages 1754-1764.
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Yue Yang, Minkyung Bae, Bohkyung Kim, Young-Ki Park, Sung I. Koo & Ji-Young Lee. (2016) Astaxanthin prevents and reverses the activation of mouse primary hepatic stellate cells. The Journal of Nutritional Biochemistry 29, pages 21-26.
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Pei-Jie Chen, Shuang-Peng Cai, Yang Yang, Wan-Xia Li, Cheng Huang, Xiao-Ming Meng & Jun Li. (2016) PTP1B confers liver fibrosis by regulating the activation of hepatic stellate cells. Toxicology and Applied Pharmacology 292, pages 8-18.
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Claus Hellerbrand. (2015) Role of Fibroblast Growth Factors and Their Receptors in Liver Fibrosis and Repair. Current Pathobiology Reports 3:4, pages 235-241.
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Joeri Lambrecht, Inge Mannaerts & Leo A. van Grunsven. (2015) The role of miRNAs in stress-responsive hepatic stellate cells during liver fibrosis. Frontiers in Physiology 6.
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Jun Xu & Tatiana Kisseleva. (2015) Bone marrow-derived fibrocytes contribute to liver fibrosis. Experimental Biology and Medicine 240:6, pages 691-700.
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Nilesh P. Talele, Julie Fradette, John E. Davies, Andras Kapus & Boris Hinz. (2015) Expression of α-Smooth Muscle Actin Determines the Fate of Mesenchymal Stromal Cells. Stem Cell Reports 4:6, pages 1016-1030.
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Daniel Shouval & Scott L. Friedman. (2014) Focusing on the past, present, and future of hepatology. Journal of Hepatology 61:6, pages 1196-1198.
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Keiko Iwaisako, Kojiro Taura, Yukinori Koyama, Kenji Takemoto & Masataka Asagiri. (2014) Strategies to Detect Hepatic Myofibroblasts in Liver Cirrhosis of Different Etiologies. Current Pathobiology Reports 2:4, pages 209-215.
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Peter Fickert, Marion J. Pollheimer, Ulrich Beuers, Carolin Lackner, Gideon Hirschfield, Chantal Housset, Verena Keitel, Christoph Schramm, Hanns-Ulrich Marschall, Tom H. Karlsen, Espen Melum, Arthur Kaser, Bertus Eksteen, Mario Strazzabosco, Michael Manns & Michael Trauner. (2014) Characterization of animal models for primary sclerosing cholangitis (PSC). Journal of Hepatology 60:6, pages 1290-1303.
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Cristina Machado Bragança de Moraes, Shanna Bitencourt, Fernanda Cristina de Mesquita, Denizar Mello, Leticia Paranhos de Oliveira, Gabriela Viegas da Silva, Vinicius Lorini, Eduardo Caberlon, Bruno de Souza Basso, Julia Schmid, Gabriela Acevedo Ferreira & Jarbas Rodrigues de Oliveira. (2014) (+)-Catechin attenuates activation of hepatic stellate cells. Cell Biology International 38:4, pages 526-530.
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D. Firrincieli, T. Braescu, C. Housset & N. Chignard. (2014) Illuminating liver fibrosis with vitamin D. Clinics and Research in Hepatology and Gastroenterology 38:1, pages 5-8.
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Xiao Liu, Jun Xu, David A. Brenner & Tatiana Kisseleva. (2013) Reversibility of Liver Fibrosis and Inactivation of Fibrogenic Myofibroblasts. Current Pathobiology Reports 1:3, pages 209-214.
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