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Cell Cycle Volume 12, 2013 - Issue 4

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Cell Cycle News & Views

A new BET on the control of HIV latency

Jonathan Karn Department of Molecular Biology and Microbiology; Case School of Medicine; Cleveland, OH USACorrespondence[email protected]

Pages 545-546 | Published online: 31 Jan 2013

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https://doi.org/10.4161/cc.23679

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Zhi-Qiang Wang, Zhao-Cong Zhang, Yu-Yang Wu, Ya-Nan Pi, Sheng-Han Lou, Tian-Bo Liu, Ge Lou & Chang Yang. (2023) Bromodomain and extraterminal (BET) proteins: biological functions, diseases, and targeted therapy. Signal Transduction and Targeted Therapy 8:1.
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Jiawei Guo, Qingquan Zheng & Yong Peng. (2023) BET proteins: Biological functions and therapeutic interventions. Pharmacology & Therapeutics 243, pages 108354.
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Thanarat Salahong, Christian Schwartz & Rungroch Sungthong. (2021) Are BET Inhibitors yet Promising Latency-Reversing Agents for HIV-1 Reactivation in AIDS Therapy?. Viruses 13:6, pages 1026.
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Xuan-xuan Zhang, Jian Lin, Tai-zhen Liang, Heng Duan, Xing-hua Tan, Bao-min Xi, Lin Li & Shu-wen Liu. (2018) The BET bromodomain inhibitor apabetalone induces apoptosis of latent HIV-1 reservoir cells following viral reactivation. Acta Pharmacologica Sinica 40:1, pages 98-110.
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Grant R. Campbell, Rachel S. Bruckman, Shayna D. Herns, Shweta Joshi, Donald L. Durden & Stephen A. Spector. (2018) Induction of autophagy by PI3K/MTOR and PI3K/MTOR/BRD4 inhibitors suppresses HIV-1 replication. Journal of Biological Chemistry 293:16, pages 5808-5820.
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Huachao Huang, Shuai Liu, Maxime Jean, Sydney Simpson, He Huang, Mark Merkley, Tsuyoshi Hayashi, Weili Kong, Irene Rodríguez-Sánchez, Xiaofeng Zhang, Hailemichael O. Yosief, Hongyu Miao, Jianwen Que, James J. Kobie, James Bradner, Netty G. Santoso, Wei Zhang & Jian Zhu. (2017) A Novel Bromodomain Inhibitor Reverses HIV-1 Latency through Specific Binding with BRD4 to Promote Tat and P-TEFb Association. Frontiers in Microbiology 8.
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Zora Melkova, Prakash Shankaran, Michaela Madlenakova & Josef Bodor. (2016) Current views on HIV-1 latency, persistence, and cure. Folia Microbiologica 62:1, pages 73-87.
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Biswajit Das, Curtis Dobrowolski, Abdel-Malek Shahir, Zhimin Feng, Xiaolan Yu, Jinfeng Sha, Nabil F. Bissada, Aaron Weinberg, Jonathan Karn & Fengchun Ye. (2015) Short chain fatty acids potently induce latent HIV-1 in T-cells by activating P-TEFb and multiple histone modifications. Virology 474, pages 65-81.
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David F. Tough, Inmaculada Rioja & Rab K. Prinjha. 2015. Histone Recognition. Histone Recognition 199 223 .

Xiangming Hu, Xiaodong Lu, Runzhong Liu, Nanping Ai, Zhenhua Cao, Yannan Li, Jiangfang Liu, Bin Yu, Kai Liu, Huiping Wang, Chao Zhou, Yu Wang, Aidong Han, Feng Ding & Ruichuan Chen. (2014) Histone Cross-talk Connects Protein Phosphatase 1α (PP1α) and Histone Deacetylase (HDAC) Pathways to Regulate the Functional Transition of Bromodomain-containing 4 (BRD4) for Inducible Gene Expression. Journal of Biological Chemistry 289:33, pages 23154-23167.
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Uri Mbonye & Jonathan Karn. (2014) Transcriptional control of HIV latency: Cellular signaling pathways, epigenetics, happenstance and the hope for a cure. Virology 454-455, pages 328-339.
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Nancie M. Archin & David M. Margolis. (2014) Emerging strategies to deplete the HIV reservoir. Current Opinion in Infectious Diseases 27:1, pages 29-35.
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Ruichuan Chen, Jasper H. N. Yik, Qiao Jing Lew & Sheng-Hao Chao. (2014) Brd4 and HEXIM1: Multiple Roles in P-TEFb Regulation and Cancer. BioMed Research International 2014, pages 1-11.
Crossref

Alexander Tarakhovsky. 2013. 107 133 .

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