697
Views
28
CrossRef citations to date
0
Altmetric
Report

Chromatin PTEN is involved in DNA damage response partly through regulating Rad52 sumoylation

, &
Pages 3442-3447 | Received 10 Sep 2013, Accepted 11 Sep 2013, Published online: 18 Sep 2013

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Mo Chen, Tianmu Wen, Hudson T. Horn, Vishwanatha K. Chandrahas, Narendra Thapa, Suyong Choi, Vincent L. Cryns & Richard A. Anderson. (2020) The nuclear phosphoinositide response to stress. Cell Cycle 19:3, pages 268-289.
Read now
Prerna Malaney, Emily Palumbo, Jonathan Semidey-Hurtado, Jamaal Hardee, Katherine Stanford, Jaymin J. Kathiriya, Deepal Patel, Zhi Tian, Diane Allen-Gipson & Vrushank Davé. (2018) PTEN Physically Interacts with and Regulates E2F1-mediated Transcription in Lung Cancer. Cell Cycle 17:8, pages 947-962.
Read now
Zhiyuan Shen. (2013) PTEN sumo-wrestles human RAD52 to mystery land. Cell Cycle 12:23, pages 3585-3585.
Read now

Articles from other publishers (25)

Jason G. Dumelie, Qiuying Chen, Dawson Miller, Nabeel Attarwala, Steven S. Gross & Samie R. Jaffrey. (2023) Biomolecular condensates create phospholipid-enriched microenvironments. Nature Chemical Biology.
Crossref
Casey G. Langdon. (2023) Nuclear PTEN’s Functions in Suppressing Tumorigenesis: Implications for Rare Cancers. Biomolecules 13:2, pages 259.
Crossref
Byeong Hyeok Choi, Tania Marlyn Colon, Eunji Lee, Ziyue Kou & Wei Dai. (2021) CBX8 interacts with chromatin PTEN and is involved in regulating mitotic progression. Cell Proliferation 54:11.
Crossref
Sandip Misra, Ginia Ghosh, Sougata Ghosh Chowdhury & Parimal Karmakar. (2021) Non-canonical function of nuclear PTEN and its implication on tumorigenesis. DNA Repair 107, pages 103197.
Crossref
Takashi Kato, Tatsuya Yamada, Hideki Nakamura, Atsushi Igarashi, Robert A. Anders, Hiromi Sesaki & Miho Iijima. (2020) The Loss of Nuclear PTEN Increases Tumorigenesis in a Preclinical Mouse Model for Hepatocellular Carcinoma. iScience 23:10, pages 101548.
Crossref
Xinyi Fan, Jeffrey Kraynak, Jonathan P.S. Knisely, Silvia C. Formenti & Wen H. Shen. (2020) PTEN as a Guardian of the Genome: Pathways and Targets. Cold Spring Harbor Perspectives in Medicine 10:9, pages a036194.
Crossref
Jason Ho, Edward S. Cruise, Ryan J.O. Dowling & Vuk Stambolic. (2020) PTEN Nuclear Functions. Cold Spring Harbor Perspectives in Medicine 10:5, pages a036079.
Crossref
Augusto Nogueira, Mara Fernandes, Raquel Catarino & Rui Medeiros. (2019) RAD52 Functions in Homologous Recombination and Its Importance on Genomic Integrity Maintenance and Cancer Therapy. Cancers 11:11, pages 1622.
Crossref
Bolin Hou, Shanshan Xu, Yang Xu, Quan Gao, Caining Zhang, Ling Liu, Huaiyi Yang, Xuejun Jiang & Yongsheng Che. (2019) Grb2 binds to PTEN and regulates its nuclear translocation to maintain the genomic stability in DNA damage response. Cell Death & Disease 10:8.
Crossref
Satoru Matsuda, Yuka Ikeda, Mutsumi Murakami, Yukie Nakagawa, Ai Tsuji & Yasuko Kitagishi. (2019) Roles of PI3K/AKT/GSK3 Pathway Involved in Psychiatric Illnesses. Diseases 7:1, pages 22.
Crossref
Parker L. Sulkowski, Susan E. Scanlon, Sebastian Oeck & Peter M. Glazer. (2018) PTEN Regulates Nonhomologous End Joining By Epigenetic Induction of NHEJ1/XLF. Molecular Cancer Research 16:8, pages 1241-1254.
Crossref
Takeshi Yasuda, Wataru Kagawa, Tomoo Ogi, Takamitsu A. Kato, Takehiro Suzuki, Naoshi Dohmae, Kazuya Takizawa, Yuka Nakazawa, Matthew D. Genet, Mika Saotome, Michio Hama, Teruaki Konishi, Nakako Izumi Nakajima, Masaharu Hazawa, Masanori Tomita, Manabu Koike, Katsuko Noshiro, Kenichi Tomiyama, Chizuka Obara, Takaya Gotoh, Ayako Ui, Akira Fujimori, Fumiaki Nakayama, Fumio Hanaoka, Kaoru Sugasawa, Ryuichi Okayasu, Penny A. Jeggo & Katsushi Tajima. (2018) Novel function of HATs and HDACs in homologous recombination through acetylation of human RAD52 at double-strand break sites. PLOS Genetics 14:3, pages e1007277.
Crossref
Byeong H. Choi, Steve Xie & Wei Dai. (2017) PTEN is a negative regulator of mitotic checkpoint complex during the cell cycle. Experimental Hematology & Oncology 6:1.
Crossref
Davide Caruso, Anselmo Papa, Silverio Tomao, Patrizia Vici, Pierluigi Benedetti Panici & Federica Tomao. (2017) Niraparib in ovarian cancer: results to date and clinical potential. Therapeutic Advances in Medical Oncology 9:9, pages 579-588.
Crossref
Yinan Kan, Nizar N. Batada & Eric A. Hendrickson. (2017) Human somatic cells deficient for RAD52 are impaired for viral integration and compromised for most aspects of homology-directed repair. DNA Repair 55, pages 64-75.
Crossref
Youn-Jung Kang, Barbara Balter, Eva Csizmadia, Brian Haas, Himanshu Sharma, Roderick Bronson & Catherine T. Yan. (2017) Contribution of classical end-joining to PTEN inactivation in p53-mediated glioblastoma formation and drug-resistant survival. Nature Communications 8:1.
Crossref
Kritika Hanamshet, Olga Mazina & Alexander Mazin. (2016) Reappearance from Obscurity: Mammalian Rad52 in Homologous Recombination. Genes 7:9, pages 63.
Crossref
Stéphane Collaud, Verena Tischler, Andrej Atanassoff, Thomas Wiedl, Paul Komminoth, Christian Oehlschlegel, Walter Weder & Alex Soltermann. (2015) Lung neuroendocrine tumors: correlation of ubiquitinylation and sumoylation with nucleo-cytosolic partitioning of PTEN. BMC Cancer 15:1.
Crossref
Mahmoud Toulany & H. Peter Rodemann. (2015) Phosphatidylinositol 3-kinase/Akt signaling as a key mediator of tumor cell responsiveness to radiation. Seminars in Cancer Biology 35, pages 180-190.
Crossref
Anand Krishnan & Douglas W. Zochodne. (2014) Is Cytoplasmic PTEN a Specific Target for Neuronal Survival?. Molecular Neurobiology 52:3, pages 1758-1764.
Crossref
Carlo C. Campa, Miriam Martini, Maria C. De Santis & Emilio Hirsch. (2015) How PI3K-derived lipids control cell division. Frontiers in Cell and Developmental Biology 3.
Crossref
Xiao Zou, Gal Levy-Cohen & Michael Blank. (2015) Molecular functions of NEDD4 E3 ubiquitin ligases in cancer. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1856:1, pages 91-106.
Crossref
Lindsay A. Bonsignore, Jill Sergesketter Butler, Carolyn M. Klinge & Christine E. Schaner Tooley. (2015) Loss of the N-terminal methyltransferase NRMT1 increases sensitivity to DNA damage and promotes mammary oncogenesis. Oncotarget 6:14, pages 12248-12263.
Crossref
Sandip Misra, Ananda Mukherjee & Parimal Karmakar. (2014) Phosphorylation of PTEN at STT motif is associated with DNA damage response. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 770, pages 112-119.
Crossref
Byeong Hyeok Choi, Michele Pagano & Wei Dai. (2014) Plk1 Protein Phosphorylates Phosphatase and Tensin Homolog (PTEN) and Regulates Its Mitotic Activity during the Cell Cycle. Journal of Biological Chemistry 289:20, pages 14066-14074.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.