2,478
Views
61
CrossRef citations to date
0
Altmetric
Extra Views

Reconciliation of classification systems defining molecular subtypes of colorectal cancer

Interrelationships and clinical implications

, , , , , & show all
Pages 353-357 | Received 12 Dec 2013, Accepted 08 Jan 2014, Published online: 09 Jan 2014

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (1)

Ulf Hammerling, Jonas Bergman Laurila, Roland Grafström & Nils-Gunnar Ilbäck. (2016) Consumption of Red/Processed Meat and Colorectal Carcinoma: Possible Mechanisms Underlying the Significant Association. Critical Reviews in Food Science and Nutrition 56:4, pages 614-634.
Read now

Articles from other publishers (60)

Manish Pratap Singh, Sandhya Rai, Sarvesh K. Gupta, Nand K. Singh & Sameer Srivastava. (2023) Unsupervised machine learning-based clustering identifies unique molecular signatures of colorectal cancer with distinct clinical outcomes. Genes & Diseases 10:6, pages 2270-2273.
Crossref
Jaime González-Montero, Mauricio Burotto, Guillermo Valenzuela, Debora Mateluna, Florencia Buen-Abad, Jessica Toro, Olga Barajas & Katherine Marcelain. (2023) Classification of patients with metastatic colorectal cancer into consensus molecular subtypes into real-world: A pilot study. World Journal of Clinical Oncology 14:10, pages 409-419.
Crossref
Lawrence D. Wagman, David A. Geller, Samuel A. Jacobs, Nicholas J. Petrelli, Carmen J. Allegra, Corey Lipchik, Katherine L. Pogue‐Geile, Ashok Srinivasan, Ying Wang & Michael J. O'Connell. (2022) NSABP FC‐6: Surgical conversion rate in colorectal cancer patients with unresectable, KRAS wild‐type liver metastases receiving mFOLFOX7 plus cetuximab. Journal of Surgical Oncology 126:8, pages 1494-1503.
Crossref
Saima Hassan, Joe W. Gray & Laura M. Heiser. 2017. Holland‐Frei Cancer Medicine. Holland‐Frei Cancer Medicine 1 11 .
Alya R Alnuaimi, Vidhya A Nair, Lara J Bou Malhab, Eman Abu-Gharbieh, Anu Vinod Ranade, Gianfranco Pintus, Mohamad Hamad, Hauke Busch, Jutta Kirfel, Rifat Hamoudi & Wael M Abdel-Rahman. (2022) Emerging role of caldesmon in cancer: A potential biomarker for colorectal cancer and other cancers. World Journal of Gastrointestinal Oncology 14:9, pages 1637-1653.
Crossref
Mamoru Ito, Michitaka Nakano, Hiroshi Ariyama, Kyoko Yamaguchi, Risa Tanaka, Yuichiro Semba, Takeshi Sugio, Kohta Miyawaki, Yoshikane Kikushige, Shinichi Mizuno, Taichi Isobe, Kenro Tanoue, Ryosuke Taguchi, Shohei Ueno, Takahito Kawano, Masaharu Murata, Eishi Baba & Koichi Akashi. (2022) Macrophages are primed to transdifferentiate into fibroblasts in malignant ascites and pleural effusions. Cancer Letters 532, pages 215597.
Crossref
Kathleen M. McAndrews, Karina Vázquez-Arreguín, Changsoo Kwak, Hikaru Sugimoto, Xiaofeng Zheng, Bingrui Li, Michelle L. Kirtley, Valerie S. LeBleu & Raghu Kalluri. (2021) αSMA+ fibroblasts suppress Lgr5+ cancer stem cells and restrain colorectal cancer progression. Oncogene 40:26, pages 4440-4452.
Crossref
Yuru Shang, Xianbin Zhang, Lili Lu, Ke Jiang, Mathias Krohn, Stephanie Matschos, Christina Susanne Mullins, Brigitte Vollmar, Dietmar Zechner, Peng Gong & Michael Linnebacher. (2021) Pharmaceutical immunoglobulin G impairs anti-carcinoma activity of oxaliplatin in colon cancer cells. British Journal of Cancer 124:8, pages 1411-1420.
Crossref
Manish Pratap Singh, Sandhya Rai, Ashutosh Pandey, Nand K. Singh & Sameer Srivastava. (2021) Molecular subtypes of colorectal cancer: An emerging therapeutic opportunity for personalized medicine. Genes & Diseases 8:2, pages 133-145.
Crossref
Begum Dariya & Ganji Purnachandra Nagaraju. 2021. Colon Cancer Diagnosis and Therapy. Colon Cancer Diagnosis and Therapy 1 13 .
Joyce Y. Buikhuisen, Arezo Torang & Jan Paul Medema. (2020) Exploring and modelling colon cancer inter-tumour heterogeneity: opportunities and challenges. Oncogenesis 9:7.
Crossref
Judith E.K.R. Hentzen, Willemijn Y. van der Plas, Hendrien Kuipers, Swades Ramcharan, Lukas B. Been, Frederik J.H. Hoogwater, Robert J. van Ginkel, Gooitzen M. van Dam, Patrick H.J. Hemmer & Schelto Kruijff. (2020) Delta peritoneal cancer index (ΔPCI): A new dynamic prognostic parameter for survival in patients with colorectal peritoneal metastases. European Journal of Surgical Oncology 46:4, pages 590-599.
Crossref
Francis Yew Fu Tieng, Rashidah Baharudin, Nadiah Abu, Ryia-Illani Mohd Yunos, Learn-Han Lee & Nurul-Syakima Ab Mutalib. (2020) Single Cell Transcriptome in Colorectal Cancer—Current Updates on Its Application in Metastasis, Chemoresistance and the Roles of Circulating Tumor Cells. Frontiers in Pharmacology 11.
Crossref
Aditi Bhatt & Olivier Glehen. 2020. Pathology of Peritoneal Metastases. Pathology of Peritoneal Metastases 67 87 .
Michele Pietrafesa, Francesca Maddalena, Luciana Possidente, Valentina Condelli, Pietro Zoppoli, Valeria Li Bergolis, Maria Grazia Rodriquenz, Michele Aieta, Giulia Vita, Franca Esposito & Matteo Landriscina. (2019) Gene Copy Number and Post-Transductional Mechanisms Regulate TRAP1 Expression in Human Colorectal Carcinomas. International Journal of Molecular Sciences 21:1, pages 145.
Crossref
Laura M. López‐Sánchez, Rafael Jiménez‐Izquierdo, Jon Peñarando, Rafael Mena, Silvia Guil‐Luna, Marta Toledano, Francisco Conde, Carlos Villar, César Díaz, Ignacio Ortea, Juan R. De la Haba‐Rodríguez, Enrique Aranda & Antonio Rodríguez‐Ariza. (2019) SWATH‐based proteomics reveals processes associated with immune evasion and metastasis in poor prognosis colorectal tumours. Journal of Cellular and Molecular Medicine 23:12, pages 8219-8232.
Crossref
Pawan Poudel, Gift Nyamundanda, Yatish Patil, Maggie Chon U Cheang & Anguraj Sadanandam. (2019) Heterocellular gene signatures reveal luminal-A breast cancer heterogeneity and differential therapeutic responses. npj Breast Cancer 5:1.
Crossref
Judith E. K. R. Hentzen, Koen P. Rovers, Hendrien Kuipers, Willemijn Y. van der Plas, Lukas B. Been, Frederik J. H. Hoogwater, Robert J. van Ginkel, Patrick H. J. Hemmer, Gooitzen M. van Dam, Ignace H. J. T. de Hingh & Schelto Kruijff. (2019) Impact of Synchronous Versus Metachronous Onset of Colorectal Peritoneal Metastases on Survival Outcomes After Cytoreductive Surgery (CRS) with Hyperthermic Intraperitoneal Chemotherapy (HIPEC): A Multicenter, Retrospective, Observational Study. Annals of Surgical Oncology 26:7, pages 2210-2221.
Crossref
Wei Wang, Raju Kandimalla, Hao Huang, Lina Zhu, Ying Li, Feng Gao, Ajay Goel & Xin Wang. (2019) Molecular subtyping of colorectal cancer: Recent progress, new challenges and emerging opportunities. Seminars in Cancer Biology 55, pages 37-52.
Crossref
Avani Athauda, Eva Segelov, Zohra Ali & Ian Chau. (2019) Integrative molecular analysis of colorectal cancer and gastric cancer: What have we learnt?. Cancer Treatment Reviews 73, pages 31-40.
Crossref
Elizabeth Alwers, Min Jia, Matthias Kloor, Hendrik Bläker, Hermann Brenner & Michael Hoffmeister. (2019) Associations Between Molecular Classifications of Colorectal Cancer and Patient Survival: A Systematic Review. Clinical Gastroenterology and Hepatology 17:3, pages 402-410.e2.
Crossref
Xavier Sagaert, Arno Vanstapel & Sanne Verbeek. (2019) Tumorheterogenität des kolorektalen Karzinoms: Was wir bisher wissen. Kompass Onkologie 6:2, pages 76-88.
Crossref
Rob Glynne-Jones & Marcia Hall. 2019. Comprehensive Rectal Cancer Care. Comprehensive Rectal Cancer Care 407 444 .
Mandana Kamgar & W. Michael Korn. 2019. Textbook of Gastrointestinal Oncology. Textbook of Gastrointestinal Oncology 613 631 .
Katherine Eason, Gift Nyamundanda & Anguraj Sadanandam. (2018) polyClustR: defining communities of reconciled cancer subtypes with biological and prognostic significance. BMC Bioinformatics 19:1.
Crossref
Ugo Testa, Elvira Pelosi & Germana Castelli. (2018) Colorectal Cancer: Genetic Abnormalities, Tumor Progression, Tumor Heterogeneity, Clonal Evolution and Tumor-Initiating Cells. Medical Sciences 6:2, pages 31.
Crossref
Xavier Sagaert, Arno Vanstapel & Sanne Verbeek. (2018) Tumor Heterogeneity in Colorectal Cancer: What Do We Know So Far?. Pathobiology 85:1-2, pages 72-84.
Crossref
Komal Qureshi-Baig, Pit Ullmann, Serge Haan & Elisabeth Letellier. (2017) Tumor-Initiating Cells: a criTICal review of isolation approaches and new challenges in targeting strategies. Molecular Cancer 16:1.
Crossref
Woo Gyeong Kim, Joo Yeon Kim & Do Youn Park. (2017) Simple classifiers for molecular subtypes of colorectal cancer. Arab Journal of Gastroenterology 18:4, pages 191-200.
Crossref
Laura A. E. Hughes, Colinda C. J. M. Simons, Piet A. van den Brandt, Manon van Engeland & Matty P. Weijenberg. (2017) Lifestyle, Diet, and Colorectal Cancer Risk According to (Epi)genetic Instability: Current Evidence and Future Directions of Molecular Pathological Epidemiology. Current Colorectal Cancer Reports 13:6, pages 455-469.
Crossref
K Trumpi, I Ubink, A Trinh, M Djafarihamedani, J M Jongen, K M Govaert, S G Elias, S R van Hooff, J P Medema, M M Lacle, L Vermeulen, I H M Borel Rinkes & O Kranenburg. (2017) Neoadjuvant chemotherapy affects molecular classification of colorectal tumors. Oncogenesis 6:7, pages e357-e357.
Crossref
R. Glynne-Jones, L. Wyrwicz, E. Tiret, G. Brown, C. Rödel, A. Cervantes & D. Arnold. (2017) Rectal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Annals of Oncology 28, pages iv22-iv40.
Crossref
Claudio Isella, Francesco Brundu, Sara E. Bellomo, Francesco Galimi, Eugenia Zanella, Roberta Porporato, Consalvo Petti, Alessandro Fiori, Francesca Orzan, Rebecca Senetta, Carla Boccaccio, Elisa Ficarra, Luigi Marchionni, Livio Trusolino, Enzo Medico & Andrea Bertotti. (2017) Selective analysis of cancer-cell intrinsic transcriptional traits defines novel clinically relevant subtypes of colorectal cancer. Nature Communications 8:1.
Crossref
Huipeng Li, Elise T Courtois, Debarka Sengupta, Yuliana Tan, Kok Hao Chen, Jolene Jie Lin Goh, Say Li Kong, Clarinda Chua, Lim Kiat Hon, Wah Siew Tan, Mark Wong, Paul Jongjoon Choi, Lawrence J K Wee, Axel M Hillmer, Iain Beehuat Tan, Paul Robson & Shyam Prabhakar. (2017) Reference component analysis of single-cell transcriptomes elucidates cellular heterogeneity in human colorectal tumors. Nature Genetics 49:5, pages 708-718.
Crossref
M. Del Rio, C. Mollevi, F. Bibeau, N. Vie, J. Selves, J.-F. Emile, P. Roger, C. Gongora, J. Robert, N. Tubiana-Mathieu, M. Ychou & P. Martineau. (2017) Molecular subtypes of metastatic colorectal cancer are associated with patient response to irinotecan-based therapies. European Journal of Cancer 76, pages 68-75.
Crossref
Cornelis J. A. Punt, Miriam Koopman & Louis Vermeulen. (2016) From tumour heterogeneity to advances in precision treatment of colorectal cancer. Nature Reviews Clinical Oncology 14:4, pages 235-246.
Crossref
Francesca Maddalena, Vittorio Simeon, Giulia Vita, Annamaria Bochicchio, Luciana Possidente, Lorenza Sisinni, Giacomo Lettini, Valentina Condelli, Danilo Swann Matassa, Valeria Li Bergolis, Alberto Fersini, Sante Romito, Michele Aieta, Antonio Ambrosi, Franca Esposito & Matteo Landriscina. (2017) TRAP1 protein signature predicts outcome in human metastatic colorectal carcinoma. Oncotarget 8:13, pages 21229-21240.
Crossref
Saima Hassan, Laura M. Heiser & Joe W. Gray. 2016. Holland-Frei Cancer Medicine. Holland-Frei Cancer Medicine 1 10 .
Nuria Rodriguez-Salas, Gema Dominguez, Rodrigo Barderas, Marta Mendiola, Xabier García-Albéniz, Juan Maurel & Jaime Feliu Batlle. (2017) Clinical relevance of colorectal cancer molecular subtypes. Critical Reviews in Oncology/Hematology 109, pages 9-19.
Crossref
Vincent Vuaroqueaux, Anne-Lise Peille, Bruno Zeitouni, Anne-Marie Eades-Perner & Heinz-Herbert Fiebig. 2017. Patient-Derived Mouse Models of Cancer. Patient-Derived Mouse Models of Cancer 227 243 .
Elisa Fontana, Krisztian Homicsko, Katherine Eason & Anguraj Sadanandam. (2016) Molecular Classification of Colon Cancer: Perspectives for Personalized Adjuvant Therapy. Current Colorectal Cancer Reports 12:6, pages 296-302.
Crossref
Katie S. Lennard, Ryan W. Goosen & Jonathan M. Blackburn. (2016) Bacterially-Associated Transcriptional Remodelling in a Distinct Genomic Subtype of Colorectal Cancer Provides a Plausible Molecular Basis for Disease Development. PLOS ONE 11:11, pages e0166282.
Crossref
T T Vellinga, S den Uil, I H B Rinkes, D Marvin, B Ponsioen, A Alvarez-Varela, S Fatrai, C Scheele, D A Zwijnenburg, H Snippert, L Vermeulen, J P Medema, H B Stockmann, J Koster, R J A Fijneman, J de Rooij & O Kranenburg. (2016) Collagen-rich stroma in aggressive colon tumors induces mesenchymal gene expression and tumor cell invasion. Oncogene 35:40, pages 5263-5271.
Crossref
Jonathan A. Nowak & Jason L. Hornick. (2016) Molecular Evaluation of Colorectal Adenocarcinoma. Surgical Pathology Clinics 9:3, pages 427-439.
Crossref
A. Morley-Bunker, L. C. Walker, M. J. Currie, J. Pearson & T. Eglinton. (2016) Translating colorectal cancer genetics into clinically useful biomarkers. Colorectal Disease 18:8, pages 749-762.
Crossref
Annelies W. Turksma, Veerle M.H. Coupé, Marc C. Shamier, Kevin L.H. Lam, Vincent A. de Weger, Jeroen A.M. Belien, Alfons J. van den Eertwegh, Gerrit A. Meijer, Chris J.L.M. Meijer & Erik Hooijberg. (2016) Extent and Location of Tumor-Infiltrating Lymphocytes in Microsatellite-Stable Colon Cancer Predict Outcome to Adjuvant Active Specific Immunotherapy. Clinical Cancer Research 22:2, pages 346-356.
Crossref
Nathalie Britzen-Laurent, Christian Herrmann, Elisabeth Naschberger, Roland S Croner & Michael Stürzl. (2016) Pathophysiological role of guanylate-binding proteins in gastrointestinal diseases. World Journal of Gastroenterology 22:28, pages 6434.
Crossref
Elaine E. Storm, Steffen Durinck, Felipe de Sousa e Melo, Jarrod Tremayne, Noelyn Kljavin, Christine Tan, Xiaofen Ye, Cecilia Chiu, Thinh Pham, Jo-Anne Hongo, Travis Bainbridge, Ron Firestein, Elizabeth Blackwood, Ciara Metcalfe, Eric W. Stawiski, Robert L. Yauch, Yan Wu & Frederic J. de Sauvage. (2015) Targeting PTPRK-RSPO3 colon tumours promotes differentiation and loss of stem-cell function. Nature 529:7584, pages 97-100.
Crossref
Victor Moreno & Rebeca Sanz-Pamplona. (2015) Altered pathways and colorectal cancer prognosis. BMC Medicine 13:1.
Crossref
Anguraj Sadanandam, Stephan Wullschleger, Costas A. Lyssiotis, Carsten Grötzinger, Stefano Barbi, Samantha Bersani, Jan Körner, Ismael Wafy, Andrea Mafficini, Rita T. Lawlor, Michele Simbolo, John M. Asara, Hendrik Bläker, Lewis C. Cantley, Bertram Wiedenmann, Aldo Scarpa & Douglas Hanahan. (2015) A Cross-Species Analysis in Pancreatic Neuroendocrine Tumors Reveals Molecular Subtypes with Distinctive Clinical, Metastatic, Developmental, and Metabolic Characteristics. Cancer Discovery 5:12, pages 1296-1313.
Crossref
N. P. Tobin, T. Foukakis, L. De Petris & J. Bergh. (2015) The importance of molecular markers for diagnosis and selection of targeted treatments in patients with cancer. Journal of Internal Medicine 278:6, pages 545-570.
Crossref
Ana Sebio & Heinz-Josef Lenz. (2015) The Molecular Taxonomy of Colorectal Cancer: What’s New?. Current Colorectal Cancer Reports 11:3, pages 118-124.
Crossref
Alexandre Calon, Enza Lonardo, Antonio Berenguer-Llergo, Elisa Espinet, Xavier Hernando-Momblona, Mar Iglesias, Marta Sevillano, Sergio Palomo-Ponce, Daniele V F Tauriello, Daniel Byrom, Carme Cortina, Clara Morral, Carles Barceló, Sebastien Tosi, Antoni Riera, Camille Stephan-Otto Attolini, David Rossell, Elena Sancho & Eduard Batlle. (2015) Stromal gene expression defines poor-prognosis subtypes in colorectal cancer. Nature Genetics 47:4, pages 320-329.
Crossref
Claudio Isella, Andrea Terrasi, Sara Erika Bellomo, Consalvo Petti, Giovanni Galatola, Andrea Muratore, Alfredo Mellano, Rebecca Senetta, Adele Cassenti, Cristina Sonetto, Giorgio Inghirami, Livio Trusolino, Zsolt Fekete, Mark De Ridder, Paola Cassoni, Guy Storme, Andrea Bertotti & Enzo Medico. (2015) Stromal contribution to the colorectal cancer transcriptome. Nature Genetics 47:4, pages 312-319.
Crossref
Teodoro VargasJuan Moreno-RubioJesús HerranzPaloma CejasSusana MolinaMargarita González-VallinasMarta MendiolaEmilio BurgosCristina AguayoAna B. CustodioIsidro MachadoDavid RamosMeritxell GironellaIsabel Espinosa-SalinasRicardo RamosRoberto Martín-HernándezAlberto RisueñoJavier De Las RivasGuillermo RegleroRicardo YayaCarlos Fernández-MartosJorge AparicioJoan MaurelJaime FeliuAna Ramírez de Molina. (2015) ColoLipidGene: signature of lipid metabolism-related genes to predict prognosis in stage-II colon cancer patients. Oncotarget 6:9, pages 7348-7363.
Crossref
Lloyd Pereira, John M. Mariadason, Ross D. Hannan & Amardeep S. Dhillon. (2015) Implications of Epithelial–Mesenchymal Plasticity for Heterogeneity in Colorectal Cancer. Frontiers in Oncology 5.
Crossref
Janneke F. Linnekamp, Xin Wang, Jan Paul Medema & Louis Vermeulen. (2015) Colorectal Cancer Heterogeneity and Targeted Therapy: A Case for Molecular Disease Subtypes. Cancer Research 75:2, pages 245-249.
Crossref
Teodoro Vargas, Juan Moreno-Rubio, Jesús Herranz, Paloma Cejas, Susana Molina, Margarita González-Vallinas, Ricardo Ramos, Emilio Burgos, Cristina Aguayo, Ana B. Custodio, Guillermo Reglero, Jaime Feliu & Ana Ramírez de Molina. (2014) Genes associated with metabolic syndrome predict disease‐free survival in stage II colorectal cancer patients. A novel link between metabolic dysregulation and colorectal cancer. Molecular Oncology 8:8, pages 1469-1481.
Crossref
Benjamin L. Emmink, Jamila Laoukili, Anna P. Kipp, Jan Koster, Klaas M. Govaert, Szabolcs Fatrai, Andre Verheem, Ernst J.A. Steller, Regina Brigelius-Flohé, Connie R. Jimenez, Inne H.M. Borel Rinkes & Onno Kranenburg. (2014) GPx2 Suppression of H2O2 Stress Links the Formation of Differentiated Tumor Mass to Metastatic Capacity in Colorectal Cancer. Cancer Research 74:22, pages 6717-6730.
Crossref
Anguraj Sadanandam, Joe Gray & Douglas Hanahan. (2014) Reply to Colorectal cancer classification based on gene expression is not associated with FOLFIRI response. Nature Medicine 20:11, pages 1231-1232.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.